mark pepys (29 resultados)

Hardcover. Condición: Very Good. Estado de la sobrecubierta: Good. First Edition. First Edition, same date of 1947; lg. 8vo, textured blue cloth, vg (spine ends and corners bumped and worn; erased pencil writing to margins of pp3 and 47; crease to edge of fold-out map) in good dj (spine and edges sunned; soiled; tears and scar to middle of spine; erased pencil notes on rear panel; edges chipped, torn and worn). 473pp incl. index.

Condición: Good. Boards have some wear, soiling marks, fading, scuffs to spine. Content has light toning. Ex libris to paste down. Book has a lean.

HARDCOVER. Condición: Very Good. London: Collins, 1937. First Edition. Numerous illustrations, fold-out map. Light wear, some discoloration to covers, a Very Good copy.

Thick large 8vo, original cloth, light rubbing and foxing, 473pp. Folding map inserted. Numerous halftone plate illustrations. His trip was accomplished, from New York to Los Angeles and San Francisco, with the help of automobile, bus, airplane & boat. He did 11,000 miles in 15 days, more than half of it in a Chrysler "Airflow." First Edition. BLISS #62.

hardcover. Condición: Good. 1932 first cassell edition on blue cloth some intermittent spotting.

Condición: New. In.

Hardcover. Condición: Good. No jacket. Cover has shelf and edge wear. Pages are clean and intact.

Paperback / softback. Condición: New. New copy - Usually dispatched within 7-11 working days.

Condición: New. pp. 232.

Paperback. Condición: Brand New. 228 pages. 9.53x6.69x0.53 inches. In Stock.

Taschenbuch. Condición: Neu. Acute Phase Proteins in the Acute Phase Response | Mark B. Pepys | Taschenbuch | xviii | Englisch | 2012 | Springer | EAN 9781447117414 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.

Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The discovery of C-reactive protein in the laboratory of O. T. Avery at Rockefeller University in 1929-30 was the first specific obser vation of the acute phase plasma protein response (Tillett and Francis 1930). This was one of three contributions of fundamental importance which emerged from that laboratory, the other two being the recognition that polysaccharides could act as antigens and that DNA transmits genetic information. In the course of charac terization of pneumococcal carbohydrate antigens, a somatic poly saccharide common to all Rand S forms of pneumococci was identified and designated Fraction 'C' (Tillet et al. 1930). Testing of sera from patients with pneumococcal infection revealed the presence of material which precipitated with the C-polysaccharide but which differed from antibody in that calcium was required for the reaction. Furthermore, the amount of reactive material was greatest when patients were acutely ill and decreased in the convalescent phase, the precise opposite of specific anti-pneumo coccal antibodies. Subsequently, the C-reactive material was shown to be a protein and to be present in the sera of individuals who were acutely ill with other, non-pneumococcal infections and tissue damaging conditions, hence Avery coined the term 'acute phase' and called the protein 'acute phase protein' (Abernethy and Avery 1941; MacLeod and Avery 1941). At that time methods were too insensitive to detect C-reative protein (CRP) in sera of healthy subjects and it was considered to be a pathological product.

Octavo, black buckram boards, grey lettering to spine, 335pp, VG (spine cocked, moderate scuffing & bruising to extrems, moderate fading & chafing to spine, sl chafing to boards, light to moderate tanning & foxing/soiling to page edges, light tanning to eps, light cracking to gutters, light occasional soiling to pages).

FIRST EDITION 8vo. grey/blue textured cloth hardback, silver gilt. No dust jacket. 335pp. Modern bookplate to front pastedown. Occasional light foxing, heavy to foredge. A VERY GOOD COPY. (Shelf 89) Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.** Pictures available upon request.** Visit our homepage for our shop opening hours. Over 20,000 books in stock - come and browse. PayPal, credit and most debit cards welcome. Books posted worldwide. For any queries please contact us direct.

Soft cover. Condición: Good. No Jacket. 1st Edition. Pepys, Mark, 6th Earl of Cottenham. All out : the story of Tom Furness's adventure. First edition. London: Cassell and Company Limited, 1932. Hardback, Good. Blue cloth, bumped to corners and top/base of spine; minor damage to base of spine. A few small marks and blemishes to boards. Binding firm, slightly cocked forward. Small ownership signature to ffep. Foxing to prelims and final two pages. 335pp., contents clean and bright. Mark Everard Pepys, 6th Earl of Cottenham (29 May 1903 19 July 1943) was an English peer, baronet, motor racing driver, member of the House of Lords, and MI5 officer. Cottenham's novel All Out (1932), dedicated to the widow of his old racing companion Henry Segrave, tells the story of a group of motoring friends fighting a gang of international criminals and includes a dramatic racing crash which was drawn from experience. RightWayUp Books aims to provide accurate and detailed descriptions. All images are of the actual book for sale - no stock images are ever used.

FIRST EDITION. 8vo., dark grey clothbound hardback with silver gilt letters to spine; 358pp. Ink owner name dated 1936 to ffep. Light browning and foxing to edges, endpapers and prelims, boards a little worn at outer corners, a few small marks to front, spine a little sunned, ends chipped, short closed tear to top, lettering starting to flake. Good+ copy overall. No dust jacket. (Shelf 130) PLEASE NOTE: Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.** Pictures available upon request.** Visit our homepage for our shop opening hours. Over 20,000 books in stock - come and browse. PayPal, credit and most debit cards welcome. Books posted worldwide. For any queries please contact us direct.

FIRST EDITION. 8vo. dark grey clothbound hardback, silver gilt. 358pp. Previous owner's attractive bookplate to inside front cover. Light rubbing to bottom of spine and corners of front cover with wear to top of spine, including small closed tears, otherwise a VERY GOOD COPY. No dust jacket. (Shelf 2) Buyer is responsible for any additional duties, taxes, or fees required by recipient's country.** Pictures available upon request.** Visit our homepage for our shop opening hours. Over 20,000 books in stock - come and browse. PayPal, credit and most debit cards welcome. Books posted worldwide. For any queries please contact us direct.

Hardcover. Condición: Very good. First edition. First edition, first impression. 8vo. Original cloth. Dust-jacket, priced 16/-. A travel narrative recording Lord Cottenham's journey across the United States. He drives by motor-car from New York to Los Angeles, returns by aeroplane, spends time in Hollywood, and takes a police-escorted tour through San Francisco's nightlife. Bookplate to front pastedown; cloth very good; jacket chipped at head of spine and top edge of lower panel. Book.

Estado de la sobrecubierta: Poor. First Edition. A 1937 First Edition copy of Mark Pepys travel book It features several black and white photographs and a folding map and contains an overview of the authors travels across the United States This copy is complete with a worn dust jacket displaying pieces missing to the extremities The black cloth boards underneath are discoloured and worn The pages are clean despite light thumb marks to the endpapers and the remnants of a removed label to the front pastedownnbsp pp 473 A scarce copy and part of a huge aviation collection just acquired by St Marys Booksnbsp. book.

2nd Edition. 2nd edition (first cheap edition) June 1934. Lacks front free endpaper. Owner's name on front pastedown. Very light scattered foxing. Black cloth very faded on spine and near rear joint. White lettering on spine. Cloth a bit worn. Binding tight. Used - Good. Good hardback (no dust jacket).

London, 1928. 155 pp. B./w. ills. Hardcover, spine sl. discol. - Exlibris on first endpaper.

First Edition. Blue cloth with silver lettering on spine; cloth a little marked & worn; spine faded, softened at head & foot, with small split in cloth at head of spine; name and address written on front free end paper; some scattered foxing; binding tight. Used - Good. Good hardback (no dust jacket).

London, Cassell and Co., 1932. 243 pp. Hardcover. - Edges foxed.Dedication in pen on first end-paper. - Mark Everard Pepys, 6th Earl of Cottenham (29 May 1903 - 19 July 1943) was an English peer, baronet, motor racing driver, member of the House of Lords, and MI5 officer.

Condición: new. Questo è un articolo print on demand.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The discovery of C-reactive protein in the laboratory of O. T. Avery at Rockefeller University in 1929-30 was the first specific obser vation of the acute phase plasma protein response (Tillett and Francis 1930). This was one of three contributions of fundamental importance which emerged from that laboratory, the other two being the recognition that polysaccharides could act as antigens and that DNA transmits genetic information. In the course of charac terization of pneumococcal carbohydrate antigens, a somatic poly saccharide common to all Rand S forms of pneumococci was identified and designated Fraction 'C' (Tillet et al. 1930). Testing of sera from patients with pneumococcal infection revealed the presence of material which precipitated with the C-polysaccharide but which differed from antibody in that calcium was required for the reaction. Furthermore, the amount of reactive material was greatest when patients were acutely ill and decreased in the convalescent phase, the precise opposite of specific anti-pneumo coccal antibodies. Subsequently, the C-reactive material was shown to be a protein and to be present in the sera of individuals who were acutely ill with other, non-pneumococcal infections and tissue damaging conditions, hence Avery coined the term 'acute phase' and called the protein 'acute phase protein' (Abernethy and Avery 1941; MacLeod and Avery 1941). At that time methods were too insensitive to detect C-reative protein (CRP) in sera of healthy subjects and it was considered to be a pathological product. 232 pp. Englisch.

Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. 1 Interleukin-1 in the Acute Phase Response.- The Acute Phase Response.- Structure of IL-1.- Synthesis and Regulation of IL-1.- IL-1 Receptor.- Pleotropic Actions of IL-1.- IL-1 and Acute Phase Reactions.- Fever.- Leukocytosis.- Acute Phase Proteins.- IL-1 .

Condición: New. Print on Demand pp. 232 45 Figures, 67:B&W 6.69 x 9.61 in or 244 x 170 mm (Pinched Crown) Perfect Bound on White w/Gloss Lam.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -1 Interleukin-1 in the Acute Phase Response.- The Acute Phase Response.- Structure of IL-1.- Synthesis and Regulation of IL-1.- IL-1 Receptor.- Pleotropic Actions of IL-1.- IL-1 and Acute Phase Reactions.- IL-1 and Other Cytokines.- In Vivo Action of IL-1.- Summary.- 2 Regulation of Human SAA Gene Expression by Cytokines.- In Vitro Expression of Human SAA.- Cis-acting Sequences Responsible for PMA Induction of SAA.- Cytokine Control of SAA Expression.- 3 Transcriptional Regulation of Acute Phase Response Genes with Emphasis on the Human C-reactive Protein Gene.- The Physiological Role of the Acute Phase Response.- Systems for the Study of the Acute Phase Response.- Monokines Responsible for the Modulation of Liver-specific Gene Expression.- Transcriptional Regulation - the Mechanism.- Conclusions and Perspectives.- 4 Organization, Structure and Expression of Pentraxin Genes.- The Structure of Pentraxin Proteins.- The Structure of Pentraxin Genes.- Elements Responding to Cytokines.- Genetics.- 5 ApoSSA: Structure, Tissue Expression and Possible Functions.- SAA is an Apolipoprotein.- Where are SAAs Made and Where do They go .- 6 Regulation of Biosynthesis and Secretion of Human C-reactive Protein and Serum Amyloid A.- Regulation of Biosynthesis.- Heterogeneity in the Acute Phase Response.- Regulation of CRP Secretion.- CRP is Specifically Retained Within the Endoplasmic Reticulum.- Conclusions.- 7 Molecular Regulation of the Acute Phase Complement Proteins.- Factor B.- The Second Component, C2.- Constitutive Expression of Factor B and C2.- Regulated Gene Expression.- Interleukin-1 and Interferon- .- Tumor Necrosis Factor and Interleukin-6.- Summary.- 8 Biosynthesis of Acute Phase Proteins by the Liver Cells.- Role of Hepatocytes in the In Vivo Biosynthesis of APR.-Role of Sinusoidal Cells in the In Vivo Biosynthesis of APR.- Summary.- 9 The Plasma Serine Protease Inhibitors (Serpins): Structural Modifications in Inflammation.- The Serpins.- Antitrypsin.- The Reactive Centre.- The SR Conformational Change.- Other Structural Modifications in Inflammation.- Conclusions.- 10 The Three Dimensional Structure of SAP.- 11 Structure, Metabolism and Function of Acute Phase High Density Lipoprotein.- Apo-SAA in Plasma.- Structure of Apo-SAA.- Structure of Acute Phase HDL.- Metabolic Function of Normal HDL.- Synthesis of Apo-SAA.- Plasma Clearance of Apo-SAA.- Cellular Association and Degradation of Apo-SAA.- Functions of Apo-SAA.- Concluding Remarks.- 12 Clinical Measurement of Acute Phase Proteins to Detect and Monitor Infectious Diseases.- Microbial Growth and AP Protein Response.- Monitoring Disease Activity Using AP Protein Response.- Immunomodulation and AP Protein Response.- 13 C-reactive Protein: Clinical Aspects.- The Acute Phase Proteins.- The Erythrocyte Sedimentation Rate as an Indirect Indicator for the Acute Phase Reaction.- C-reactive Protein as a Direct Indicator of the Acute Phase Reaction.- Conclusion.- 14 Pathogenesis of AA Amyloidosis.- Definition and Classification of Amyloidosis.- Serum and Tissue Amyloid A Proteins.- Structure of SAA and AA.- Formation and Deposition of AA Amyloid.- Summary of Some Current Hypotheses Regarding AA Amyloid Formation.- 15 Serum Amyloid P Component: A Specific Molecular Targeting Vehicle in Amyloidosis.- Serum Amyloid P Component.- SAP and Amyloidosis.- Scintigraphic Imaging of Amyloid Deposits In Vivo.- Radiolabeled SAP Studies in Man.- Conclusions.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 232 pp. Englisch.

Condición: New. PRINT ON DEMAND pp. 232.