Librería: Books Puddle, New York, NY, Estados Unidos de America
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Añadir al carritoCondición: New. pp. 126.
EUR 76,59
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Añadir al carritoPaperback. Condición: Brand New. 1st edition. 118 pages. 8.75x6.00x0.50 inches. In Stock.
Idioma: Inglés
Publicado por Springer International Publishing, Springer, 2014
ISBN 10: 3319050257 ISBN 13: 9783319050256
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 53,49
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Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation. These two related, multi-subunit E3 ubiquitin ligase enzymes, APC and SCF are thought to be the major driving forces governing proper cell cycle progression. Defective cell cycle regulation leads to genomic instability and ultimately, cancer development. Selective degradation of key cell cycle regulators by the ubiquitin-proteasome system has been proven to be a major regulatory mechanism for ensuring ordered and coordinated cell cycle progression. The SCF and APC E3 ligases have been characterized to play pivotal roles in regulating the cell cycle progression by timely degrading various critical cell cycle regulators. This Brief reviews recent studies that have shown that deregulation of signaling pathways in which the two ubiquitin ligases are involved causes aberrant cell cycle regulation, in turn leading to tumorigenesis. The text also discusses how SCF and APC may present promising therapeutic targets to treat various cancers.
Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 162,37
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Librería: Ria Christie Collections, Uxbridge, Reino Unido
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Librería: GreatBookPrices, Columbia, MD, Estados Unidos de America
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Librería: GreatBookPricesUK, Woodford Green, Reino Unido
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Librería: GreatBookPrices, Columbia, MD, Estados Unidos de America
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Librería: GreatBookPricesUK, Woodford Green, Reino Unido
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Librería: Books Puddle, New York, NY, Estados Unidos de America
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Añadir al carritoCondición: New. 1st ed. 2020 edition NO-PA16APR2015-KAP.
Librería: Books Puddle, New York, NY, Estados Unidos de America
EUR 212,95
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Añadir al carritoCondición: New. pp. VIII, 372 119 illus., 68 illus. in color. 1st ed. 2020 edition NO-PA16APR2015-KAP.
Librería: preigu, Osnabrück, Alemania
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Añadir al carritoTaschenbuch. Condición: Neu. Cullin-RING Ligases and Protein Neddylation | Biology and Therapeutics | Yi Sun (u. a.) | Taschenbuch | Advances in Experimental Medicine and Biology | viii | Englisch | 2021 | Springer | EAN 9789811510274 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Idioma: Inglés
Publicado por Springer Nature Singapore, Springer Nature Singapore, 2020
ISBN 10: 9811510245 ISBN 13: 9789811510243
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 166,62
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Añadir al carritoBuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 168,73
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Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine.
Librería: Revaluation Books, Exeter, Reino Unido
EUR 235,49
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Añadir al carritoPaperback. Condición: Brand New. 380 pages. 10.00x7.01x0.90 inches. In Stock.
Librería: Revaluation Books, Exeter, Reino Unido
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Añadir al carritoHardcover. Condición: Brand New. 382 pages. 10.00x7.00x1.10 inches. In Stock.
Idioma: Inglés
Publicado por Springer International Publishing Apr 2014, 2014
ISBN 10: 3319050257 ISBN 13: 9783319050256
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
EUR 53,49
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Añadir al carritoTaschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This SpringerBrief explores the physiological roles of Skp1-Cullin1-F-box Complex (SCF) and Anaphase Promoting Complex (APC) in normal cells and in tumor formation. These two related, multi-subunit E3 ubiquitin ligase enzymes, APC and SCF are thought to be the major driving forces governing proper cell cycle progression. Defective cell cycle regulation leads to genomic instability and ultimately, cancer development. Selective degradation of key cell cycle regulators by the ubiquitin-proteasome system has been proven to be a major regulatory mechanism for ensuring ordered and coordinated cell cycle progression. The SCF and APC E3 ligases have been characterized to play pivotal roles in regulating the cell cycle progression by timely degrading various critical cell cycle regulators. This Brief reviews recent studies that have shown that deregulation of signaling pathways in which the two ubiquitin ligases are involved causes aberrant cell cycle regulation, in turn leading to tumorigenesis. The text also discusses how SCF and APC may present promising therapeutic targets to treat various cancers. 124 pp. Englisch.
Librería: Majestic Books, Hounslow, Reino Unido
EUR 76,52
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Añadir al carritoCondición: New. Print on Demand pp. 126 11 Illus. (Col.).
Librería: Biblios, Frankfurt am main, HESSE, Alemania
EUR 72,19
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Añadir al carritoCondición: New. PRINT ON DEMAND pp. 126.
Idioma: Inglés
Publicado por Springer International Publishing, 2014
ISBN 10: 3319050257 ISBN 13: 9783319050256
Librería: moluna, Greven, Alemania
EUR 48,37
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Añadir al carritoCondición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes updated profiles of SCF and APC cellular functions and their characterized ubiquitin substratesIntroduces the emergent SCF family members in the human genome and summarizes phenotypes in which the adapter proteins of SCF and APC are manip.
Librería: Brook Bookstore On Demand, Napoli, NA, Italia
EUR 126,26
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Librería: Brook Bookstore On Demand, Napoli, NA, Italia
EUR 126,26
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Añadir al carritoCondición: new. Questo è un articolo print on demand.
Idioma: Inglés
Publicado por Springer Nature Singapore Jan 2020, 2020
ISBN 10: 9811510245 ISBN 13: 9789811510243
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
EUR 160,49
Cantidad disponible: 2 disponibles
Añadir al carritoBuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine. 380 pp. Englisch.
Idioma: Inglés
Publicado por Springer Nature Singapore Jan 2021, 2021
ISBN 10: 981151027X ISBN 13: 9789811510274
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
EUR 160,49
Cantidad disponible: 2 disponibles
Añadir al carritoTaschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book summarizes all the important aspects of CRLs (Cullin-RING E3 Ubiquitin Ligases), while providing details of mechanistic specifics that go beyond protein ubiquitination and neddylation. Ubiquitin ligases, including the CRLs, which are activated by neddylation, play an important role in diverse biological processes and are involved in various human diseases, particularly cancer. The book covers various topics, such as CRL structure, biology, genetics, its regulation by neddylation, its pivotal role in human disease, and its potential in drug discovery and targeted therapies. The book appeals to biochemists and biologists working in other fields, and, given the importance of CRLs in all aspects of cell biology and the great promise of targeting these complexes for therapy, is a valuable resource anyone interested in modern biology or medicine. 380 pp. Englisch.
Librería: moluna, Greven, Alemania
EUR 136,16
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Añadir al carritoCondición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Summarizes all the important aspects of CRLsProvides potential strategies for targeting various human diseasesWritten by pioneers in the field of ubiquitin and neddylationDr. Yi Sun.
Librería: moluna, Greven, Alemania
EUR 136,16
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Añadir al carritoGebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Summarizes all the important aspects of CRLsProvides potential strategies for targeting various human diseasesWritten by pioneers in the field of ubiquitin and neddylationDr. Yi Sun.
Librería: Majestic Books, Hounslow, Reino Unido
EUR 201,10
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Librería: Majestic Books, Hounslow, Reino Unido
EUR 201,63
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Añadir al carritoCondición: New. Print on Demand pp. VIII, 372 119 illus., 68 illus. in color.
Librería: Biblios, Frankfurt am main, HESSE, Alemania
EUR 203,37
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Librería: Biblios, Frankfurt am main, HESSE, Alemania
EUR 203,70
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Añadir al carritoCondición: New. PRINT ON DEMAND pp. VIII, 372 119 illus., 68 illus. in color.