Tushar kshirsagar (35 resultados)

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Paperback. Condición: Brand New. reprint edition. 243 pages. 9.75x6.75x0.50 inches. In Stock.

Condición: Hervorragend. Zustand: Hervorragend | Seiten: 256 | Sprache: Englisch | Produktart: Bücher | A single source on parallel synthesis for lead optimization, this book features real-world examples and contributions from well-known scientists. It explores the shift to conducting parallel lead optimization in-house while outsourcing most of the screening libraries synthesis. With more than 15 case studies that encompass a range of biological targets for application in different therapeutic areas, the text contains examples of solid and solution-phase techniques for the synthesis of directed libraries. The authors explain the design principles they used to direct the choice of templates and diversity elements and they explore how this technology, when applied to library design, can speed up drug discovery.…

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HRD. Condición: New. New Book. Shipped from UK. Established seller since 2000.

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Condición: New. pp. 256.

Hardcover. Condición: new. Hardcover. A Single Source on Parallel Synthesis for Lead OptimizationThe end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library development is necessary to generate high quality hits. More recently, the use of parallel synthesis techniques has shifted to applications beyond screening collections. Exploring the nuances of this technology, High-Throughput Lead Optimization in Drug Discovery describes the application of parallel synthesis to lead optimization and the design and synthesis of targeted libraries. Examine Case Studies that Cover a Range of Different Biological Targets Featuring real-world examples and contributions from well-known scientists, the book explores the shift to conducting parallel lead optimization in-house while outsourcing most of the screening libraries synthesis. It includes more than 15 case studies that encompass a range of biological targets for application in different therapeutic areas. The text contains examples of solid and solution-phase techniques for the synthesis of directed libraries. The chapter authors explain the design principles they used to direct the choice of templates and diversity elements. Speed Up Drug Discovery and the Hit-to-Lead Process Focusing on the application of combinatorial chemistry to medicinal chemistry, this volume compiles a series of optimization projects that give you a snapshot of successes and challenges in the use of parallel synthesis for lead optimization. It explores how this technology, when applied to library design, can speed up drug discovery. Describes the application of parallel synthesis to lead optimization and the design and synthesis of targeted libraries. This book examines case studies that cover different biological targets. It explores the shift to conducting parallel lead optimization in-house while outsourcing the screening libraries synthesis. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

Hardcover. Condición: Brand New. 1st edition. 243 pages. 10.00x7.25x0.75 inches. In Stock.

Condición: New. Tushar KshirsagarA Single Source on Parallel Synthesis for Lead OptimizationThe end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. .

Condición: New. pp. 256.

Condición: New. Describes the application of parallel synthesis to lead optimization and the design and synthesis of targeted libraries. This book examines case studies that cover different biological targets. It explores the shift to conducting parallel lead optimization in-house while outsourcing the screening libraries synthesis. Editor(s): Kshirsagar, Tushar. Series: Critical Reviews in Combinatorial Chemistry. Num Pages: 256 pages, 177 black & white illustrations, 37 black & white tables. BIC Classification: TDCW. Category: (P) Professional & Vocational. Dimension: 254 x 178. Weight in Grams: 589. . 2008. Hardback. . . . .…

Buch. Condición: Neu. Neuware - A Single Source on Parallel Synthesis for Lead OptimizationThe end of the previous millennium saw an explosion in the application of parallel synthesis techniques for making compounds for high-throughput screening. Over time, it became clear that more thought in the design phase of library development is necessary to generate high quality hits. More recently, the use of parallel synthesis techniques has shifted to applications beyond screening collections. Exploring the nuances of this technology, High-Throughput Lead Optimization in Drug Discovery describes the application of parallel synthesis to lead optimization and the design and synthesis of targeted libraries. Examine Case Studies that Cover a Range of Different Biological Targets Featuring real-world examples and contributions from well-known scientists, the book explores the shift to conducting parallel lead optimization in-house while outsourcing most of the screening libraries synthesis. It includes more than 15 case studies that encompass a range of biological targets for application in different therapeutic areas. The text contains examples of solid and solution-phase techniques for the synthesis of directed libraries. The chapter authors explain the design principles they used to direct the choice of templates and diversity elements. Speed Up Drug Discovery and the Hit-to-Lead Process Focusing on the application of combinatorial chemistry to medicinal chemistry, this volume compiles a series of optimization projects that give you a snapshot of successes and challenges in the use of parallel synthesis for lead optimization. It explores how this technology, when applied to library design, can speed up drug discovery.…

Hardcover. Condición: Brand New. 1st edition. 243 pages. 10.00x7.25x0.75 inches. In Stock.