Petronis arturas (32 resultados)

Hardcover. Condición: fine. no jacket. 1st edition. Hardcover, 230 pages, many b/w illustrations. There is a compact plastic disc with digital data at rear inside cover "After introducing basic statistics, the disc describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systemic artifacts resulting from measurement imperfections". "Explores well-established statistical methods, such as linear and Markov models, clustering, and t, f, and permutation tests.". many b/w illustrations (ilustrador).…

Condición: Sehr gut. Zustand: Sehr gut | Seiten: 336 | Sprache: Englisch | Produktart: Bücher | Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions? Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease? If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment? Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.…

Condición: As New. Unread book in perfect condition.

Condición: New.

Condición: As New. Unread book in perfect condition.

Condición: New.

Condición: New. A brand new book in pristine condition. Showing zero signs of shelf wear, creases, or damage.

Condición: New.

Condición: New.

Condición: As New. Unread book in perfect condition.

Condición: As New. Unread book in perfect condition.

Taschenbuch. Condición: Neu. Brain, Behavior and Epigenetics | Arturas Petronis (u. a.) | Taschenbuch | Epigenetics and Human Health | xvi | Englisch | 2013 | Springer | EAN 9783642268328 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Condición: New. In English.

Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Epigenetic processes can explain some of the epidemiological associations between environmental exposure and disease, particularly when the exposure occurs at a critical delopmental stage.Epigenetics, a cellular mechanism once considered to be stable after development, has now been found to be a dynamic process that occurs in fully differentiated, post-mitotic cells of central nervous system in response to environmental signals. Epigenetic mechanisms regulate the structure of the chromatin through post-translational modifications of histone proteins and covalent DNA modifications. Though the mechanisms through which these effects are achieved likely involve diverse cellular and molecular pathways, there is emerging evidence supporting the hypothesis that epigenetic changes, such as DNA methylation and histone modifications, may mediate the effects of early-life variations in the social interactions between mothers and infants.…

Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.…

Condición: New. In English.

Condición: New. pp. 336.

Condición: New. pp. 336.

Paperback. Condición: Brand New. 2011 edition. 345 pages. 9.00x6.10x0.80 inches. In Stock.

Hardcover. Condición: Brand New. 1st edition. 317 pages. 9.50x6.25x0.75 inches. In Stock.

Condición: new. Questo è un articolo print on demand.

Condición: new. Questo è un articolo print on demand.

Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Art Petronis and Jon Mill s research is dedicated to the understanding of the role of epigenetic risk factors in complex diseasesEpigenetic processes can explain some of the epidemiological associations between environmental exposure and disease..…

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Art Petronis and Jon Mill s research is dedicated to the understanding of the role of epigenetic risk factors in complex diseasesEpigenetic processes can explain some of the epidemiological associations between environmental exposure and disease..…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases. 336 pp. Englisch.…

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Epigenetic processes can explain some of the epidemiological associations between environmental exposure and disease, particularly when the exposure occurs at a critical delopmental stage.Epigenetics, a cellular mechanism once considered to be stable after development, has now been found to be a dynamic process that occurs in fully differentiated, post-mitotic cells of central nervous system in response to environmental signals. Epigenetic mechanisms regulate the structure of the chromatin through post-translational modifications of histone proteins and covalent DNA modifications. Though the mechanisms through which these effects are achieved likely involve diverse cellular and molecular pathways, there is emerging evidence supporting the hypothesis that epigenetic changes, such as DNA methylation and histone modifications, may mediate the effects of early-life variations in the social interactions between mothers and infants. 336 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -InhaltsangabePreface.-1. Post-translational histone modifications and the neurobiology of psychosis.- 2. Epigenetic regulation of GABAergic targets in psychiatry.- 3. Possible roles of DNA methylation in bipolar disorder.- 4. The epigenetics of depression and suicide.- 5. Epidemiology research and epigenetics: Translational epidemiology of schizophrenia.-6. Environmental studies as a tool for detecting epigenetic mechanisms in schizophrenia.-7. Imprinting, inactivation and the behavioural genetics of the X-chromosome.-8. The strategies of the genes: genomic conflicts, attachment theory and development of the social brain.- 9. Genomic imprinting effects on brain and behavior; future directions.- 10. Epigenetic influence of the social environment.- 11. Towards an understanding of the dynamic inter-dependence of genes and environment in the regulation of phenotype. Nurturing our epigenetic nature.-12. Histone deacetylase inhibitors: a novel therapeutic approach for cognitive disorders.-13. Epigenetic mechanisms of memory consolidation.- 14. Epigenetic mechanisms in memory formation.- Subject index.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch.…

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Biomedical research in the first decade of the 21st century has been marked by a rapidly growing interest in epigenetics. The reasons for this are numerous, but primarily it stems from the mounting realization that research programs focused solely on DNA sequence variation, despite their breadth and depth, are unlikely to address all fundamental aspects of human biology. Some questions are evident even to non-biologists. How does a single zygote develop into a complex multicellular organism composed of dozens of different tissues and hundreds of cell types, all genetically identical but performing very different functions Why do monozygotic twins, despite their stunning external similarities, often exhibit significant differences in personality and predisposition to disease If environmental factors are solely the cause of such variation, why are similar differences also observed between genetically identical animals housed in a uniform environment Over the last couple of decades, epigenetics has undergone a significant metamorphosis from an abstract developmental theory to a very dynamic and rapidly developing branch of molecular biology. This volume represents a compilation of our current understanding about the key aspects of epigenetic processes in the brain and their role in behavior. The chapters in this book bring together some of the leading researchers in the field of behavioral epigenetics. They explore many of the epigenetic processes which operate or may be operating to mediate neurobiological functions in the brain and describe how perturbations to these systems may play a key role in mediating behavior and the origin of brain diseases.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 336 pp. Englisch.…

Condición: New. Print on Demand pp. 336.

Condición: New. Print on Demand pp. 336.