Karthickeyan (22 resultados)

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Taschenbuch. Condición: Neu. Drug-drug interactions of gemfibrozil and rosiglitazone-Indian study | Krishnan Karthickeyan (u. a.) | Taschenbuch | 104 S. | Englisch | 2014 | LAP LAMBERT Academic Publishing | EAN 9783659115264 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The study designed to investigate the effect of gemfibrozil on the pharmacokinetics of rosiglitazone in Indian healthy adult male volunteers. This prospective open label randomized two-way crossover study was conducted in 12 Indian healthy adult male volunteers after ethical committee approval. Rosiglitazone 4mg tablet was administered either with or without pre-treatment of gemfibrozil 600mg tablets twice daily for 3 days. Plasma drug concentrations from time 0 to 12 hours were estimated by validated HPLC-UV method. The pharmacokinetic parameters were calculated and compared for statistical significance and 95% confidence interval (CI). Gemfibrozil increased the bioavailability of rosiglitazone to the extent comparable with the reports found in literature. But the increased bioavailability of rosiglitazone even without interacting drug enhanced the risk of concentration dependent adverse effects of rosiglitazone in Indian subjects. This was further augmented by co-administration of gemfibrozil. These findings supported the regulator's recent decision to ban the drug in the country. 104 pp. Englisch.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The study designed to investigate the effect of gemfibrozil on the pharmacokinetics of rosiglitazone in Indian healthy adult male volunteers. This prospective open label randomized two-way crossover study was conducted in 12 Indian healthy adult male volunteers after ethical committee approval. Rosiglitazone 4mg tablet was administered either with or without pre-treatment of gemfibrozil 600mg tablets twice daily for 3 days. Plasma drug concentrations from time 0 to 12 hours were estimated by validated HPLC-UV method. The pharmacokinetic parameters were calculated and compared for statistical significance and 95% confidence interval (CI). Gemfibrozil increased the bioavailability of rosiglitazone to the extent comparable with the reports found in literature. But the increased bioavailability of rosiglitazone even without interacting drug enhanced the risk of concentration dependent adverse effects of rosiglitazone in Indian subjects. This was further augmented by co-administration of gemfibrozil. These findings supported the regulator's recent decision to ban the drug in the country.…

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Chandra Shekar MottapallyChandra Shekar. M, Studied Master of Biotechnology at University of Madras and Pursuing Doctor of Philosophy at CAS in Marine Biology, Annamali University.,India.The microsatellites markers are highly .…

Condición: New. Print on Demand pp. 104 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Karthickeyan KrishnanKrishnan Karthickeyan, clinical pharmacist in JSS college of pharmacy, ooty and also pursuing PhD in pharmaceutical sciences. Completed master of pharmacy in pharmacy practice in 2008 with gold medal and bachelor.…

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Condición: New. PRINT ON DEMAND pp. 104.

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Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The study designed to investigate the effect of gemfibrozil on the pharmacokinetics of rosiglitazone in Indian healthy adult male volunteers. This prospective open label randomized two-way crossover study was conducted in 12 Indian healthy adult male volunteers after ethical committee approval. Rosiglitazone 4mg tablet was administered either with or without pre-treatment of gemfibrozil 600mg tablets twice daily for 3 days. Plasma drug concentrations from time 0 to 12 hours were estimated by validated HPLC-UV method. The pharmacokinetic parameters were calculated and compared for statistical significance and 95% confidence interval (CI). Gemfibrozil increased the bioavailability of rosiglitazone to the extent comparable with the reports found in literature. But the increased bioavailability of rosiglitazone even without interacting drug enhanced the risk of concentration dependent adverse effects of rosiglitazone in Indian subjects. This was further augmented by co-administration of gemfibrozil. These findings supported the regulator's recent decision to ban the drug in the country.OmniScriptum SRL, Str. Armeneasca 28/1, office 1, 2012 Chisinau 104 pp. Englisch.…