Librería: Anybook.com, Lincoln, Reino Unido
EUR 17,89
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Añadir al carritoCondición: Good. This is an ex-library book and may have the usual library/used-book markings inside.This book has hardback covers. Clean from markings In good all round condition. Please note the Image in this listing is a stock photo and may not match the covers of the actual item,1250grams, ISBN:9780896035966.
Librería: GreatBookPrices, Columbia, MD, Estados Unidos de America
EUR 58,71
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Añadir al carritoCondición: As New. Unread book in perfect condition.
Librería: GreatBookPrices, Columbia, MD, Estados Unidos de America
EUR 58,95
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Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 54,51
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Librería: GreatBookPricesUK, Woodford Green, Reino Unido
EUR 54,50
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Añadir al carritoCondición: New.
Librería: GreatBookPricesUK, Woodford Green, Reino Unido
EUR 59,52
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Añadir al carritoCondición: As New. Unread book in perfect condition.
Librería: BennettBooksLtd, Los Angeles, CA, Estados Unidos de America
EUR 81,89
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Añadir al carritoHardcover. Condición: New. In shrink wrap. Looks like an interesting title!
Librería: Romtrade Corp., STERLING HEIGHTS, MI, Estados Unidos de America
EUR 102,69
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Añadir al carritoCondición: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Librería: Basi6 International, Irving, TX, Estados Unidos de America
EUR 102,69
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Añadir al carritoCondición: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Librería: SHIMEDIA, Brooklyn, NY, Estados Unidos de America
EUR 117,53
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Añadir al carritoCondición: New. Satisfaction Guaranteed or your money back.
Librería: Romtrade Corp., STERLING HEIGHTS, MI, Estados Unidos de America
EUR 129,23
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Añadir al carritoCondición: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.
Librería: Basi6 International, Irving, TX, Estados Unidos de America
EUR 129,23
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Añadir al carritoCondición: Brand New. New. US edition. Expediting shipping for all USA and Europe orders excluding PO Box. Excellent Customer Service.
Librería: Books Puddle, New York, NY, Estados Unidos de America
EUR 127,59
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Añadir al carritoCondición: Used. pp. 272.
Librería: Majestic Books, Hounslow, Reino Unido
EUR 132,43
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Añadir al carritoCondición: Used. pp. 272 69 Illus. (22 Col.).
Librería: Biblios, Frankfurt am main, HESSE, Alemania
EUR 131,49
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Añadir al carritoCondición: Used. pp. 272.
Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 164,50
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Librería: Books Puddle, New York, NY, Estados Unidos de America
EUR 177,78
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Añadir al carritoCondición: Used. pp. 472.
Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 164,50
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Librería: Majestic Books, Hounslow, Reino Unido
EUR 184,53
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Añadir al carritoCondición: Used. pp. 472.
EUR 136,16
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EUR 136,16
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Añadir al carritoGebunden. Condición: New.
EUR 84,76
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Añadir al carritoCondición: Sehr gut. Zustand: Sehr gut | Seiten: 268 | Sprache: Englisch | Produktart: Bücher | Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase inhibitor, methotrexate, and the thymidylate synthase inhibitors, raltitrexed and pemetrexed. Major advances in folate research made within the last decade include (i) the approval of pemetrexed for the treatment of lung cancer and mesothelioma, and (ii) the demonstration that cell membrane-anchored folate receptors (FR) are exploitable for cancer and inflammatory disease management. FRs are not widely distributed in normal tissues, except on some luminal surfaces; however, they are accessible to systemically administered agents when expressed on many cancers as well as on activated macrophages involved in various inflammatory diseases. High affinity folate-radioisotope conjugates have been developed for imaging pathogenic FR-positive diseases, including cancer. Since the FR transports folates via a low capacity but high affinity endocytic pathway, a variety of FR-targeted antifolate drugs and folate conjugates bearing a wide range of payloads (including cytotoxic drugs) are currently being developed which exploit this property. The FR is also being utilized in immunotherapy approaches for the treatment of overexpressing cancers.
Librería: Biblios, Frankfurt am main, HESSE, Alemania
EUR 184,23
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Añadir al carritoCondición: Used. pp. 472.
EUR 140,00
Cantidad disponible: 5 disponibles
Añadir al carritoTaschenbuch. Condición: Neu. Targeted Drug Strategies for Cancer and Inflammation | Christopher P. Leamon (u. a.) | Taschenbuch | xi | Englisch | 2014 | Springer | EAN 9781489988867 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Librería: GreatBookPricesUK, Woodford Green, Reino Unido
EUR 216,38
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Añadir al carritoCondición: New.
Librería: GreatBookPrices, Columbia, MD, Estados Unidos de America
EUR 232,69
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Añadir al carritoCondición: New.
Librería: California Books, Miami, FL, Estados Unidos de America
EUR 235,09
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Añadir al carritoCondición: New.
Idioma: Inglés
Publicado por Springer New York, Springer US, 2011
ISBN 10: 144198416X ISBN 13: 9781441984166
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 164,49
Cantidad disponible: 1 disponibles
Añadir al carritoBuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase inhibitor, methotrexate, and the thymidylate synthase inhibitors, raltitrexed and pemetrexed. Major advances in folate research made within the last decade include (i) the approval of pemetrexed for the treatment of lung cancer and mesothelioma, and (ii) the demonstration that cell membrane-anchored folate receptors (FR) are exploitable for cancer and inflammatory disease management. FRs are not widely distributed in normal tissues, except on some luminal surfaces; however, they are accessible to systemically administered agents when expressed on many cancers as well as on activated macrophages involved in various inflammatory diseases. High affinity folate-radioisotope conjugates have been developed for imaging pathogenic FR-positive diseases, including cancer. Since the FR transports folates via a low capacity but high affinity endocytic pathway, a variety of FR-targeted antifolate drugs and folate conjugates bearing a wide range of payloads (including cytotoxic drugs) are currently being developed which exploit this property. The FR is also being utilized in immunotherapy approaches for the treatment of overexpressing cancers.
Idioma: Inglés
Publicado por Springer, Springer New York, 2014
ISBN 10: 1489988866 ISBN 13: 9781489988867
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 167,14
Cantidad disponible: 1 disponibles
Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Folate pathways are essential in metabolism and macromolecule synthesis. Antifolate drugs that are largely transported via a high capacity folate transporter (i.e. the reduced-folate carrier) and inhibit folate-dependent enzymes include the dihydrofolate reductase inhibitor, methotrexate, and the thymidylate synthase inhibitors, raltitrexed and pemetrexed. Major advances in folate research made within the last decade include (i) the approval of pemetrexed for the treatment of lung cancer and mesothelioma, and (ii) the demonstration that cell membrane-anchored folate receptors (FR) are exploitable for cancer and inflammatory disease management. FRs are not widely distributed in normal tissues, except on some luminal surfaces; however, they are accessible to systemically administered agents when expressed on many cancers as well as on activated macrophages involved in various inflammatory diseases. High affinity folate-radioisotope conjugates have been developed for imaging pathogenic FR-positive diseases, including cancer. Since the FR transports folates via a low capacity but high affinity endocytic pathway, a variety of FR-targeted antifolate drugs and folate conjugates bearing a wide range of payloads (including cytotoxic drugs) are currently being developed which exploit this property. The FR is also being utilized in immunotherapy approaches for the treatment of overexpressing cancers.
Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 225,60
Cantidad disponible: Más de 20 disponibles
Añadir al carritoCondición: New. In.