Stem cell microenvironment role (45 resultados)

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Condición: New. Cristian Pablo Pennisi, Mayuri Sinha Prasad, Pranela RameshwarHow stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or .

Taschenbuch. Condición: Neu. Neuware - How stem cells behave is very much a factor of their local microenvironment, also known as the stem cell niche. Physical, chemical, or electrical signals from the neighboring cells or biochemical signals from distant cells are crucial in the cell fate decision process. A major challenge of tissue engineering is to mimic the natural cell environment by designing very sophisticated scaffolds able not only to mechanically support cells, but also to release signals biologically relevant for governing stem cell fate. In addition, increasing evidence suggests that abnormal interaction of stem cells with their niche is responsible for altered cell function leading to malignant transformation. This book discusses some of the recent advances in stem cell research that may help understanding the properties of the niche that govern stem cell fate. Technical topics discussed include:Stem cell biologyCancer stem cellsStem cell interactions with biomaterialsEngineering the stem cell microenvironmentStem cells in tissue regeneration and repairThe Disputationes Workshop series is an international initiative aimed at disseminating stem cell related cutting edge knowledge among scientists, healthcare workers, students and policy makers. This book emerges as a result of the scientific contributions presented and discussed during the fifth Disputationes Workshop held in Aalborg (Denmark) in April 2014. The stem cell microenvironment and its role in regenerative medicine and cancer pathogenesis is ideal for academic staff and master/research students in biomedical and health sciences.…

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Condición: New. pp. 144.

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Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Rhim and Kremer's state-of-the-art volume on Human Cell Transformation: Role of Stem Cells and the Microenvironment highlights the latest findings on the current state of human cell transformation model systems and provides the insight into the molecular and cellular changes involved in the conversion of normal cells to neoplastic cells.Chapters cover all recently developed novel human cell models. In addition, the rapidly growing fields of knowledge regarding not only stem cells in cancer progression, but also the role of the microenvironments in human carcinogenesis are discussed. A wealth of topics is presented including: Derivation of epithelial, fibroblastic, and hematopoietic in vitro model systems Oncogenes Tumor suppressor genes Viral transformation In vitro model systems for viral, chemical and radiation carcinogenesis Cell aging The multistep nature of human carcinogenesis The role of stem cells and the microenvironment in tumorigenesis The genes involved in multistep carcinogenesisUnique in both scope and focus - devoted solely to human cell transformation systems - Human Cell Transformation: Role of Stem Cells and the Microenvironment provides unparalleled, in-depth coverage for cancer researchers, cell and molecular biologists, hematologists, virologists, and workers in related fields.Essential reading for everyone who needs to be kept up-to-date in this fast-paced area! FeaturesØ Multistep modelsØ Breast cancer/Stem cellsØ Prostate cancer/Stem cells Ø Multistep / Genes.…

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