9781607615422 - Protein Kinase C in Cancer Signaling and Therapy (Current Cancer Research) (14 resultados)

Condición: Sehr gut. Zustand: Sehr gut | Seiten: 508 | Sprache: Englisch | Produktart: Bücher | Protein kinase C (PKC), a family of serine-threonine kinases, rocketed to the forefront of the cancer research field in the early 1980¿s with its identification as an effector of phorbol esters, natural products with tumor promoting activity. Phorbol esters had long been of interest to the cancer research field due to early studies in the mouse skin carcinogenesis model, which showed that prolonged topical application of phorbol esters promoted the formation of skin tumors on mice previously treated with mutagenic agents. Research in the last years has established key roles for PKC isozymes in the control of cell proliferation, migration, adhesion, and malignant transformation. In addition, there is a large body of evidence linking PKC to invasion and cancer cell metastasis. Moreover, it is now well established that the expression of PKC isozymes is altered in various types of cancers. More importantly, small molecule inhibitors have been developed with significant anti-cancer activity. The relevance of PKC isozymes in cancer signaling is therefore remarkable. This book will have 4 sections. There will be 23 chapters. Each section will have a brief introduction by an expert in the field (~ 1-2 pages).

Condición: New. In.

Condición: New. pp. 510.

Condición: New. Editor(s): Kazanietz, Marcelo G. Series: Current Cancer Research. Num Pages: 494 pages, 26 black & white illustrations, 11 colour illustrations, 6 black & white tables, biograph. BIC Classification: MJCL; MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 33. Weight in Grams: 1010. . 2010. Hardback. . . . .

Hardcover. Condición: Brand New. 1st edition. 494 pages. 9.25x6.25x1.25 inches. In Stock.

Hardcover. Condición: Like New. Like New. book.

Condición: New. Editor(s): Kazanietz, Marcelo G. Series: Current Cancer Research. Num Pages: 494 pages, 26 black & white illustrations, 11 colour illustrations, 6 black & white tables, biograph. BIC Classification: MJCL; MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 33. Weight in Grams: 1010. . 2010. Hardback. . . . . Books ship from the US and Ireland.

Condición: new. Questo è un articolo print on demand.

Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Focuses specifically on PKC signaling at a mechanistic level in the context of cancerThe first to present in a very detailed manner the implication of PKC isozymes in different types of cancersThere will be a full section on anticancer agen.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Protein kinase C (PKC), a family of serine-threonine kinases, rocketed to the forefront of the cancer research field in the early 1980's with its identification as an effector of phorbol esters, natural products with tumor promoting activity. Phorbol esters had long been of interest to the cancer research field due to early studies in the mouse skin carcinogenesis model, which showed that prolonged topical application of phorbol esters promoted the formation of skin tumors on mice previously treated with mutagenic agents. Research in the last years has established key roles for PKC isozymes in the control of cell proliferation, migration, adhesion, and malignant transformation. In addition, there is a large body of evidence linking PKC to invasion and cancer cell metastasis. Moreover, it is now well established that the expression of PKC isozymes is altered in various types of cancers. More importantly, small molecule inhibitors have been developed with significant anti-cancer activity. The relevance of PKC isozymes in cancer signaling is therefore remarkable.This book will have 4 sections. There will be 23 chapters. Each section will have a brief introduction by an expert in the field (~ 1-2 pages). 508 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Protein kinase C (PKC), a family of serine-threonine kinases, rocketed to the forefront of the cancer research field in the early 1980¿s with its identification as an effector of phorbol esters, natural products with tumor promoting activity. Phorbol esters had long been of interest to the cancer research field due to early studies in the mouse skin carcinogenesis model, which showed that prolonged topical application of phorbol esters promoted the formation of skin tumors on mice previously treated with mutagenic agents. Research in the last years has established key roles for PKC isozymes in the control of cell proliferation, migration, adhesion, and malignant transformation. In addition, there is a large body of evidence linking PKC to invasion and cancer cell metastasis. Moreover, it is now well established that the expression of PKC isozymes is altered in various types of cancers. More importantly, small molecule inhibitors have been developed with significant anti-cancer activity. The relevance of PKC isozymes in cancer signaling is therefore remarkable.This book will have 4 sections. There will be 23 chapters. Each section will have a brief introduction by an expert in the field (~ 1-2 pages).Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 508 pp. Englisch.

Condición: New. Print on Demand pp. 510.

Buch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Protein kinase C (PKC), a family of serine-threonine kinases, rocketed to the forefront of the cancer research field in the early 1980's with its identification as an effector of phorbol esters, natural products with tumor promoting activity. Phorbol esters had long been of interest to the cancer research field due to early studies in the mouse skin carcinogenesis model, which showed that prolonged topical application of phorbol esters promoted the formation of skin tumors on mice previously treated with mutagenic agents. Research in the last years has established key roles for PKC isozymes in the control of cell proliferation, migration, adhesion, and malignant transformation. In addition, there is a large body of evidence linking PKC to invasion and cancer cell metastasis. Moreover, it is now well established that the expression of PKC isozymes is altered in various types of cancers. More importantly, small molecule inhibitors have been developed with significant anti-cancer activity. The relevance of PKC isozymes in cancer signaling is therefore remarkable.This book will have 4 sections. There will be 23 chapters. Each section will have a brief introduction by an expert in the field (~ 1-2 pages).

Condición: New. PRINT ON DEMAND pp. 510.