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Publicado por Humana Press, New York, 2009
ISBN 10: 1603273344 ISBN 13: 9781603273343
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Añadir al carritoHardback. Condición: Very Good. x + 290 pp. The Receptors. Rubber-stamped on front free endpaper. book.
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Añadir al carritoCondición: New. pp. xxvi + 226 2009th edition.
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Añadir al carritoCondición: Sehr gut. Zustand: Sehr gut | Seiten: 292 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.
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Idioma: Inglés
Publicado por Humana Press Inc., Totowa, NJ, 2009
ISBN 10: 1603273344 ISBN 13: 9781603273343
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Añadir al carritoHardcover. Condición: new. Hardcover. Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, and for the design of experiments to characterize receptor function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessible and authoritative, Functional Selectivity of G Protein-Coupled Receptors is a valuable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.
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Añadir al carritoCondición: New. In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. Editor(s): Neve, Kim. Series: The Receptors. Num Pages: 292 pages, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 20. Weight in Grams: 558. . 2009. Hardback. . . . .
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Añadir al carritoCondición: New. Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at path.
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Añadir al carritoBuch. Condición: Neu. Neuware - Functional selectivity refers to the ability of different ligands acting at one receptor subtype to activate multiple signaling pathways in unique combinations; that is, one drug can be an agonist at pathway A and an antagonist or partial agonist at pathway B, and another drug can have the reverse profile. Functional selectivity has profound implications for drug development, for chemical biology, and for the design of experiments to characterize receptor function. In Functional Selectivity of G Protein-Coupled Receptors expert neuroscientists and pharmacologists review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. This exciting, comprehensive, and future-oriented volume includes chapters that focus on theoretical and mechanistic aspects of functional selectivity and that cut across subfamilies of GPCRs. Additional chapters focus on subfamilies of therapeutically relevant receptors where there is considerable evidence of ligand functional selectivity. Accessible and authoritative, Functional Selectivity of G Protein-Coupled Receptors is a valuable educational tool and reference source for students and scientists interested in drug development, chemical biology, and GPCR function.
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Añadir al carritoHardcover. Condición: Brand New. 1st edition. 290 pages. 9.25x6.25x0.75 inches. In Stock.
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Añadir al carritoCondición: New. In Functional Selectivity of G Protein-Coupled Receptors, experts review the work that demonstrated the existence of functional selectivity, placed it within a theoretical framework, and provided a mechanistic basis for the phenomenon. Editor(s): Neve, Kim. Series: The Receptors. Num Pages: 292 pages, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 235 x 155 x 20. Weight in Grams: 558. . 2009. Hardback. . . . . Books ship from the US and Ireland.
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Añadir al carritoHardcover. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
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