9781493937356 - thyroid hormone disruption and neurodevelopment (contemporary clinical neuroscience) (12 resultados)
Idioma: Inglés
Editorial: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Midtown Scholar Bookstore, Harrisburg, PA, Estados Unidos de AmericaMidtown Scholar Bookstore
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hardcover. Condición: Very Good. No dust jacket as issued. No dust jacket. Very Good hardcover with light shelfwear - NICE! Standard-sized.
Idioma: Inglés
Editorial: Springer New York 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Buchpark, Trebbin, AlemaniaBuchpark
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Condición: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However,… the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a ¿repressor¿ of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood. ¿.
Idioma: Inglés
Editorial: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Ria Christie Collections, Uxbridge, Reino UnidoRia Christie Collections
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Condición: New. In.
Idioma: Inglés
Editorial: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Books Puddle, New York, NY, Estados Unidos de AmericaBooks Puddle
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Condición: New. pp. 260.
Idioma: Inglés
Editorial: Springer New York, Springer US 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH
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Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. However, the mo…lecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first bookto comprehensively describethe effect of thyroid hormone disruptionin the central nervous system.The first section deals with the disruption of thyroid hormone action at themolecular level. Firstthe authorsprovide a summary ofthe possible molecular mechanisms of thyroid hormone action in the brain, thenthey discussseveral factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a'repressor' of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanismsthat createeach abnormal phenotype are not fully understood.
Idioma: Inglés
Editorial: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Revaluation Books, Exeter, Reino UnidoRevaluation Books
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Hardcover. Condición: Brand New. 9.50x6.25x0.75 inches. In Stock.
Idioma: Inglés
Editorial: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand
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Condición: new. Questo è un articolo print on demand.
Idioma: Inglés
Editorial: Springer New York 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: moluna, Greven, Alemaniamoluna
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Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. The first book to describe the effects of thyroid hormone disruptions on neurodevelopmentProvides perspectives from molecular studies, animal studies, and human studies Suitable for both basic researcher…s and clinici.
Idioma: Inglés
Editorial: Springer New York Nov 2016 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans.… However, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first bookto comprehensively describethe effect of thyroid hormone disruptionin the central nervous system.The first section deals with the disruption of thyroid hormone action at themolecular level. Firstthe authorsprovide a summary ofthe possible molecular mechanisms of thyroid hormone action in the brain, thenthey discussseveral factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a'repressor' of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanismsthat createeach abnormal phenotype are not fully understood. 220 pp. Englisch.
Idioma: Inglés
Editorial: Springer, Springer US Nov 2016 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemaniabuchversandmimpf2000
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EUR 181,89
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Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Thyroid hormone plays an important role in development and functional maintenance in the central nervous system. Deficiency of thyroid hormone during fetal and early postnatal life induces abnormal development known as cretinism in humans. How…ever, the molecular mechanism of thyroid hormone action has not yet been fully understood. Thyroid hormone action in the brain may be disrupted under various pathological conditions. In addition, environmental factors including endocrine-disrupting chemicals and bacterial endotoxins may disrupt thyroid hormone action in brain, causing abnormal brain development and functional disruption. This is a first book to comprehensively describe the effect of thyroid hormone disruption in the central nervous system. The first section deals with the disruption of thyroid hormone action at the molecular level. First the authors provide a summary of the possible molecular mechanisms of thyroid hormone action in the brain, then they discuss several factors that may disrupt thyroid hormone action. In the second section, animal models to study thyroid hormone action will be introduced. An interesting character of thyroid hormone deficiency is that, without thyroid hormone, the thyroid hormone receptor may act as a 'repressor' of gene expression, causing more severe consequence than those of thyroid hormone receptor knockout animals. Thus, several different kind of animal models may be used to clarify the role of thyroid hormone and its receptor in the brain. In the third section, human studies on thyroid disease and neurodevelopment will be introduced. Although endemic cretinism induced by iodine deficiency and sporadic cretinism by various thyroid mutation are well known, the pathophysiological mechanisms that create each abnormal phenotype are not fully understood. ¿Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 220 pp. Englisch.
Idioma: Inglés
Editorial: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Majestic Books, Hounslow, Reino UnidoMajestic Books
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EUR 258,85
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Condición: New. Print on Demand pp. 260.
Idioma: Inglés
Editorial: Springer 2016
Serie: Contemporary Clinical Neuroscience, Libro 13 de 20. Libro 13 de 20 - Contemporary Clinical Neuroscience
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Librería: Biblios, frankfurt am main, HESSE, AlemaniaBiblios
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EUR 256,16
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Condición: New. PRINT ON DEMAND pp. 260.
