ISBN: 9781468498417 - anticancer drug development guide: preclinical screening, clinical trials, and approval (cancer drug discovery and development) (13 resultados)

Condición: New. In English.

Condición: New. Editor(s): Teicher, Beverly A.; Andrews, Paul A. Series: Cancer Drug Discovery and Development. Num Pages: 451 pages, 161 black & white illustrations, biography. BIC Classification: MJCL; MMG. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 24. Weight in Grams: 883. . 2012. Softcover reprint of the original 1st ed. 2004. Paperback. . . . . …

Taschenbuch. Condición: Neu. Anticancer Drug Development Guide | Preclinical Screening, Clinical Trials, and Approval | Beverly A. Teicher (u. a.) | Taschenbuch | Cancer Drug Discovery and Development | xiv | Englisch | 2012 | Humana | EAN 9781468498417 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.…

Condición: New. pp. 468.

Paperback. Condición: Brand New. reprint edition. 465 pages. 9.75x7.00x1.25 inches. In Stock.

Condición: New. Editor(s): Teicher, Beverly A.; Andrews, Paul A. Series: Cancer Drug Discovery and Development. Num Pages: 451 pages, 161 black & white illustrations, biography. BIC Classification: MJCL; MMG. Category: (P) Professional & Vocational. Dimension: 254 x 178 x 24. Weight in Grams: 883. . 2012. Softcover reprint of the original 1st ed. 2004. Paperback. . . . . Books ship from the US and Ireland. …

Condición: new. Questo è un articolo print on demand.

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This unique volume traces the critically important pathway by which a molecule becomes an anticancer agent. The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink m.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This unique volume traces the critically important pathway by which a 'molecule' becomes an 'anticancer agent. ' The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these 'anticancer' molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of 'antileukemia' agents, but that other tumor models would be needed to discover drugs active against solid tumors. 468 pp. Englisch.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This unique volume traces the critically important pathway by which a 'molecule' becomes an 'anticancer agent. ' The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these 'anticancer' molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of 'antileukemia' agents, but that other tumor models would be needed to discover drugs active against solid tumors.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This unique volume traces the critically important pathway by which a 'molecule' becomes an 'anticancer agent. ' The recognition following World War I that the administration of toxic chemicals such as nitrogen mustards in a controlled manner could shrink malignant tumor masses for relatively substantial periods of time gave great impetus to the search for molecules that would be lethal to specific cancer cells. Weare still actively engaged in that search today. The question is how to discover these 'anticancer' molecules. Anticancer Drug Development Guide: Preclinical Screening, Clinical Trials, and Approval, Second Edition describes the evolution to the present of preclinical screening methods. The National Cancer Institute's high-throughput, in vitro disease-specific screen with 60 or more human tumor cell lines is used to search for molecules with novel mechanisms of action or activity against specific phenotypes. The Human Tumor Colony-Forming Assay (HTCA) uses fresh tumor biopsies as sources of cells that more nearly resemble the human disease. There is no doubt that the greatest successes of traditional chemotherapy have been in the leukemias and lymphomas. Since the earliest widely used in vivo drug screening models were the murine L 1210 and P388 leukemias, the community came to assume that these murine tumor models were appropriate to the discovery of 'antileukemia' agents, but that other tumor models would be needed to discover drugs active against solid tumors.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 468 pp. Englisch.…

Condición: New. Print on Demand pp. 468.

Condición: New. PRINT ON DEMAND pp. 468.