Isbn: 9780387250007 - hypocretins: integrators of physiological signals (17 resultados)

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Condición: New. pp. 468.

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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The hypocretins (orexins) are a newly identified (1998) peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. Recent observations suggest an involvement of these peptides, located primarily in the hypothalmus, in the regulation of behavioral state. They are involved in circadian rhythms, metabolism, hormone secretion, body temperature, appetite, cardiovascular functions (e.g., blood pressure), and sleep abnormalities (e.g., narcolepsy and cataplexy). 468 pp. Englisch.…

Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Represents an interdisciplinary approach to hypocretins that reviews the role of these neuropeptides in neurological diseaseThe first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to.…

Buch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The hypocretins (orexins) are a newly identified (1998) peptide family comprised of two peptides, hypocretin-1 and hypocretin-2. Recent observations suggest an involvement of these peptides, located primarily in the hypothalmus, in the regulation of behavioral state. They are involved in circadian rhythms, metabolism, hormone secretion, body temperature, appetite, cardiovascular functions (e.g., blood pressure), and sleep abnormalities (e.g., narcolepsy and cataplexy).…

Buch. Condición: Neu. Hypocretins | Integrators of Physiological Signals | J. Gregor Sutcliffe (u. a.) | Buch | xxiv | Englisch | 2005 | Springer US | EAN 9780387250007 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. …

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The first report that rapid eye movements occur in sleep in humans was published in 1953. The research journey from this point to the realization that sleep consists of two entirely independent states of being (eventually labeled REM sleep and non-REM sleep) was convoluted, but by 1960 the fundamental duality of sleep was well established including the description of REM sleep in cats associated with ¿wide awake¿ EEG patterns and EMG suppression. The first report linking REM sleep to a pathology occurred in 1961 and a clear association of sleep onset REM periods, cataplexy, hypnagogic hallucinations and sleep paralysis was fully established by 1966. When a naïve individual happens to observe a full-blown cataplexy attack, it is both dramatic and unnerving. Usually the observer assumes that the loss of muscle tone represents syncope or seizure. In order to educate health professionals and the general public, Christian Guilleminault and I made movies of full-blown cataplectic episodes (not an easy task). We showed these movies of cataplexy attacks to a number of professional audiences, and were eventually rewarded with the report of a similar abrupt loss of muscle tone in a dog. We were able to bring the dog to Stanford University and with this as the trigger, we were able to develop the Stanford Canine Narcolepsy Colony. Breeding studies revealed the genetic determinants of canine narcolepsy, an autosomal recessive gene we termed canarc1. Emmanuel Mignot took over the colony in 1986 and began sequencing DNA, finally isolating canarc1 in 1999.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 468 pp. Englisch.…