springer springer jun 2000 (381 resultados)

Buch. Condición: Neu. Neuware - Modern cell biology has brought improvements in therapy for advanced malignant diseases through immunomodulation, hematopoietic stem cell transplantation, and other advanced techniques. Collected here are selected papers from the Fifth International Symposium of Keio University for Life Sciences and Medicine on Cell Therapy.All chapters include innovative basic research for clinical application: immunotherapy, cancer vaccination, molecular biology of hematopoietic stem cells, stem cell processing, and gene therapy.The book is divided into three parts: Immunotherapy for malignant diseases; Hematopoietic stem cell biology and clinical application; and International collaboration in hematopoietic stem cell transplantation. Included in the third part is information on bone marrow registries from around the world.The book thus presents up-to-date information on biological and clinical aspects of treatment, with insight into the future of cell therapy.

Buch. Condición: Neu. Neuware - The emergence of multidrug-resistant tuberculosis (MDRTB) threatens TB control programs worldwide. Outbreaks of MDRTB in the United States grabbed the attention of the medical community and the general public, and subsequent surveys have found 'hot spots' of MDRTB in low- and middle-income countries on four continents. Unlike other textbooks that contain only a single chapter on MDRTB, this book is devoted to the subject. Contributions from experts from multi disciplines provide detailed descriptions, causation, molecular biology, laboratory diagnosis, treatment, prevention, and public health, aspect of this disease. This book provides an authoritative overview of MDRTB and will be a useful reference book for clinicians, scientists and other health personnel involved in the care of TB and MDRTB patients in industrialized and developing countries.

Buch. Condición: Neu. Neuware - There have been major changes in the heat content and ice cover of the Arctic Ocean since 1990. Year after year, this observational evidence underscores the likelihood that predictions of global climatic effects will turn out to be true. Changes in the freshwater flow from the Arctic Ocean may have very significant consequences for humanity, including those alive today. It is vital that we develop the capability to predict the magnitude of such effects with far greater certainty, as well as the probability of their occurrence within a giver time frame. To do so, we need the internationally organised commitment of scientific labour and funding. This book has been written by many of the world's most knowledgable polar oceanographers, meteorologists and hydrologists, takes full account of the latest results and discusses their significance. It draws together assessments by many specialists to present an integrated view of possible future changes in the climate of the Northern hemisphere.

Buch. Condición: Neu. Neuware - The largest workshop ever held has produced the most comprehensive review of Radio Frequency Dosimetry and Bioeffects available. Over 80 of the world's leading scientists and technical experts from nine NATO countries and six NATO Partner for Peace countries, and others, review the state of the art in radio frequency radiation dosimetry, measurements and the relationship between SAR, power density and the biological effects of the electromagnetic fields.

Buch. Condición: Neu. Neuware - Dr. Olcbee Lee SchoolofEducation, UniversityofMiami Coral Gables, Florida 33124 I remember my excitement and appreciation several years ago when I first read World View Theory and Science Education Research by Bill Cobern (1991). It was a comprehensive, theoretical discussion ofworldview theory in science education. I am delighted to see that Cobern has taken the next step to provide empirical accountsofworldview in Everyday Thoughts about Nature. . The primary goal of the book is to understand how typical- ninth grade students and their science teachers think about Nature or the natural world, and how their thoughts are related to science. In pursuing this goal, the book raises a basicquestion about the purpose ofscienceeducationfor the public: Should science education seek to educate 'scientific thinkers' in the pattern of the science teachers Or, should science education seek to foster sound science learning within the matrices ofvari ous cultural perspectives (p. 3) The answer to this question becomes clear, thanks to Cobern's excellent research and persuasivearguments. First, this research takes a humanistic approach in understanding what students and teachers think about Nature 'through the language and ideas voluntarily expressed' (p. I). The research used multi directional prompts and encouraged students and teachers to speak freely and at length in any directions they wished. This humanistic approach is stated clearly: '[T]he research seeks to illuminate some of the various ways in which students think aboutNature withoutjudging eventhe most unorthodox perspectives' (p. 14).

Taschenbuch. Condición: Neu. Neuware - Agriculture is a crucial component of the economies of many of the countries in transition from a centrally-planned to a market economy and the sector is by no means immune to the environmental and socioeconomic problems confronting the countries as a whole. The concept of sustainable development provides a convenient framework for the formulation of government environmental policy for such countries, especially those of them that aspire to join the EU and would thus be expected to meet EU environmental standards. For agriculture, this inevitably involves appropriate strategies for balancing crop and animal production while protecting the quality of the national soil and water resources. There is thus an urgent need to compile, exchange and evaluate current information on the quality of soils in these countries, and to assess the potential impact of new management practices on the soil and on the wider environment.

Buch. Condición: Neu. Neuware - t/c with MS.

Buch. Condición: Neu. Neuware - Financial systems around the world are undergoing a process of modernization due to many different forces. Advances in information technology, product and market innovations, and recent regional financial crises have contributed to this movement. As a result, evolution in the financial sector is leading to larger, more complex financial organizations that render inadequate the supervisory and regulatory structures currently in place. While some changes in regulatory policies have already occurred, the adaptation of supervisory oversight and regulation in the face of these new developments is expected to continue for many years to come. This book collects papers originally presented in September 1998 at the Financial Modernization and Regulation Conference co-sponsored by the Federal Reserve Banks of Atlanta and San Francisco. Revised before publication, the papers seek to identify the reasons for changes in the financial services sector, and the implications these changes pose for financial supervision and regulation. Taken together, the papers offer valuable insights on 1) the forces behind financial modernization; 2) the implications financial modernization poses for corporate structure, market discipline, and financial regulation; 3) how to price deposit insurance accurately to reflect banks' risk-taking; and 4) balancing private versus public interests and managing potentially conflicting public policy goals.

Buch. Condición: Neu. Neuware - This important, state-of-the-art book brings together for the first time in one volume the two areas of Legacy Systems and Business Processes. The research discussed has arisen from the EPSRC research programme on Systems Engineering for Business Process Change, and the book contains contributions from leading experts in the field.Both the consumer and supplier of IT have problems with legacy systems and business process change, so Systems Engineering for Business Process Change will be of great interest to practitioners who are encountering, or likely to encounter, problems with legacy systems and business process change, as well as researchers preparing future research programmes, and those studying system and business evolution.

Buch. Condición: Neu. Neuware - Interfaces between media, whether air-water or sediment-water interfaces or organisms themselves, pose considerable problems to marine organisms attempting to live at these boundaries. In the present volume, a number of authors address various aspects of these two topics. Locations under scrutiny range from intertidal areas to the deep sea, while both macro-and meiofaunal organisms are investigated. Distribution patterns and effects of variable temperatures, pressures, and salinities are analysed. Aspects of fouling induction and prevention are also addressed. This book is intended as a progress report from the 33rd European Marine Biology Symposium held in Wilhelmshaven, Germany, in September 1998.

Buch. Condición: Neu. Neuware - System Modelling and Optimization covers research issues within systems theory, optimization, modelling, and computing. It includes contributions to structural mechanics, integer programming, nonlinear programming, interior point methods, dynamical systems, stability analysis, stochastic optimization, bilevel optimization, and semidefinite programming. Several survey papers written by leading experts in their fields complement new developments in theory and applications. This book contains most of the invited papers and a few carefully selected submitted papers that were presented at the 19th IFIP TC7 Conference on System Modelling and Optimization, which was held in Cambridge, England, from July 12 to 16, 1999, and sponsored by the International Federation for Information Processing (IFIP).

Buch. Condición: Neu. Neuware - An Aspen Food Engineering Series Book. This new reference work in the Food Engineering Series covers basic and new information and issues, and new and refined existing technologies in the preservation of fruits and vegetables with a minimum of processing. It begins with a section on detecting and controlling good and harmful microorganisms in fruits and vegetable tissues, then surveys a range of preservation technologies, talks about new technologies being developed in landmark multinational projects, and ends by covering the legal aspects of minimally processed produce in the United States, Europe, South America, and Asia.

Buch. Condición: Neu. Neuware - Efficiency and Equity of Climate Change Policy is a comprehensive assessment of the economic effects of climate change policy, addressing the issues with a quantitative modelling approach. The book thus goes beyond the usual statements on the efficiency of economic instruments to identify the way gains and losses are distributed; who gains and who loses. Both the costs and benefits of climate change policies are analyzed. Most papers also provide useful information on the economic features of the Kyoto Protocol, its possible extensions, and the effect of different implementation strategies (such as the debate on emissions trading ceilings). Readership: Scientists and policy makers, students and specialists in climate related industries, members of NGOs, and policy advisors.

Buch. Condición: Neu. Neuware - From the perspective of the investigator, Graves' disease is a fascinating disorder with unique features and opportunities for study. The discovery in 1956 that Graves' disease was caused by a humoral factor, later shown to be an antibody to the TSH receptor, was a triumph for modern investigative medicine. Rapid progress is now being made in (i) understanding the molecular interaction between autoantibodies and the TSH receptor, (ii) identifying the genes that contribute to the predisposition to disease, (iii) developing an animal model of Graves' disease, and (iv) identifying the long-sought orbital antigen in ophthalmopathy. From the clinical standpoint, although Graves' disease is eminently treatable, there is no definitive cure. None of the therapeutic options are ideal. It is hoped that rapid progress in understanding the pathogenesis of the disease will lead to the ultimate goal of some form of immunotherapy that will make antithyroid drugs, radioiodine and thyroidectomy obsolete. The chapters in Graves' Disease: Pathogenesis and Treatment represent the viewpoints of many prominent clinicians and investigators working in the field. The editors are grateful for their contributions which cover an unusually comprehensive compendium of subjects relating to the disease.

Buch. Condición: Neu. Neuware - This timely publication fills a large gap in the ophthalmic literature which has so far lacked a monograph on the clinically very important subject of macular edema. The book presents the most up-to-date scientific concepts concerning the etiology and pathogenesis of blood retinal barrier breakdown such as tight junction associated protein dysfunction, and changes in fluid transport properties of the retinal pigment epithelium. The bulk of the book is clinically oriented and addresses novel imaging and diagnostic techniques for the detection of macular edema as well as the clinical context of a panoply of ocular diseases which induce macular edema, such as diabetes, other vasculopathies, uveitis, and many others. New light is shed on the association between highly active antiretroviral therapy and the induction of macular edema in HIV-positive patients. Novel drug treatment regimens with steroids and carbonic anhydrase inhibitors as well as new ways of applying laser and surgical therapies are also discussed in detail, and practical treatment guidelines are given. This book will be helpful for vitreoretinal specialists as well as for the practising ophthalmologist confronted with patients suffering from macular edema.

Buch. Condición: Neu. Neuware - of UB's medical school, that UB developed its School of Arts and Sciences, and thus, assumed its place among the other institutions of higher education. Had Fillmore lived throughout UB's first seventy years, he would probably have been elated by the success of his university, and he should have been satisfied and pleased that UB remained intrinsically bonded to its community while at the same time engrafting the values and standards important to higher education's mission in the region. UB and its medical school have undergone many challenging transitions since 1846. Included among them were: (1) the completion of an academic campus in the far northeast comer of the City of Buffalo while leaving its medical, dental and law schools firmly situated in the core of downtown Buffalo; (2) the eventual relocation, after the second world war, of the law school to the newer campus in Amherst, and the medical and dental school to the original academic campus: and (3) the merger with the State University of New York System in 1962. Despite these significant transitions, any one of which could have changed the intrinsic integrity of UB and disrupted the bonding between community and university, that did not happen. To this day, the ties between community and academe persist. Fillmore and White should celebrate their success and important contribution to Buffalo and Western New York.

Buch. Condición: Neu. Neuware - The discovery of the human T cell leukemia virus type I in the late 1970s heralded a new era in retrovirology. For the first time, it was demonstrated that a retrovirus could play a role in the development of a human disease, in this case adult T cell leukemia (ATL). Several years later, the acquired immunodeficiency syndrome (AIDS) epidemic began, and it was dem- strated that a retrovirus, originally designated the human T cell lymp- tropic virus type 3, was the causal agent of this syndrome. This virus, later named the human immunodeficiency virus type 1 (HIV-1), has since been extensively studied in terms of its pathogenesis as well as its ability to elicit immune responses. In that time, a tremendous amount of information has been obtained about the virus. Although recent drug regimens have been useful in significantly lowering viral loads and perhaps maintaining an asymptomatic state among individuals infected with HIV-1, an established 'cure' for AIDS eludes us. In addition, the effective drug therapies are very expensive, and are not available to infected people in the third world, where greater than 90% of new infections occur. Furthermore, the development of viral resistance against the drug therapies is an additional concern. Despite extensive study, no effective vaccine has been developed. One of the problems in developing an effective vaccine against HIV-1 is the ability of the virus, particularly in the immunogenic envelop glycoprotein, to undergo amino acid hypervariability.

Taschenbuch. Condición: Neu. Neuware - For more than 25 years the Standard Model of particle physics has withstood the confrontation with experimental results of increasing precision, but this does not imply that the Standard Model can answer all questions about the ultimate constituents of nature. This book presents a critical examination of the latest experimental results and confronts them with the predictions of the Standard Model. Besides discussions of accelerator results from LEP, HERA and the TEVATRON, attention is paid to the unresolved problems of neutrino oscillations, CP violation, dark matter and cosmology. New theoretical ideas are also analyzed in order to explore possible extensions of the standard model. Realistic plans for future accelerators are presented and their physics potential is discussed, paving the way for the next generation of particle physics experiments.

Buch. Condición: Neu. Neuware - This book presents the most recent research advances in the theory, design, control and application of robotic systems, which are intended for a variety of purposes such as manipulation, manufacturing, automation, surgery, locomotion and biomechanics. The issues addressed are fundamentally kinematic in nature, including synthesis, calibration, redundancy, force control, dexterity, inverse and forward kinematics, kinematic singularities, as well as over-constrained systems. Methods used include line geometry, quaternion algebra, screw algebra, and linear algebra. These methods are applied to both parallel and serial multi-degree-of-freedom systems. The results should interest researchers, teachers and students, in fields of engineering and mathematics related to robot theory, design, control and application. All articles in the book were reported at the seventh international symposium on Advances in Robot Kinematics that was organised in June 2000 in the beautiful ancient Mediterranean town of Piran in Slovenia. The preceding symposia of the series took place in Ljubljana (1988), Linz (1990), Ferrara (1992), Ljubljana (1994), and Piran (1996), and Salzburg (1998).

Buch. Condición: Neu. Neuware - Regardless of the subject matter, our studies are always searching for a sense of the universal in the specific. Drawing, etchings and paintings are a way of communicating ideas and emotions. The key word here is to communicate. Whether the audience sees the work as laborious or poetic depends on the creative genius of the artist. Some painters use the play of light passing through a landscape or washing over a figure to create an evocative moment that will be both timeless and transitory. The essential role of art remains what is has always been, a way of human expression. This is the role that our participants concentrate on as they discuss art as the expression of the spirit, a creative act through which the artist makes manifest what is within him. Spirit suggests the unity of feeling and thought. Avoiding broad generalities, our participants address specific areas in orchestration with music, architecture, literature and phenomenology. Profs. Souiller, Scholz, Etlin, Sweetser, Josephs show us at what point art is an intimate, profound expression and the magic of a civilization as a whole, springing from its evolving thoughts and embodying ideals, such as the Renaissance, the Baroque, Modernism and at what point it reflects the trans formation of a particular society and its mode of life.

Buch. Condición: Neu. Neuware - While this book presents the results of comprehensive and cooperative international reseirch, this effort would not have been successful without the assistance of various institutions and personalities. Financial support for the conference was received from the Volkswagen Foundation, Germany, and the Deutsche Forschungsgemeinschaft (DFG) which is gratefully acknowledged. The Deutsche Ralffeisenverband kindly contributed to hosting the international group of researchers in Bonn. For their valuable comments we also thank: Uwe Eiteljorge, Johannes Jutting, Amim Kuhn, Witold-Roger Poganietz, Matin Qaim, Alexandra Schleier, Ludwig Striewe, Jllrgen Wandel, Peter Weingarten, Manfred Wiebelt and Susanna Wolf. The editors also acknowledge the help provided by James Creed, Karin Clark, and Ulla Knodt in checking language and style of the articles, most of them written by non-native speakers. Martin Grub, Tina Klebsch, and Andrea Stang have been helpful in providing technical assistance needed to prepare the manuscript. Bonn Peter Wehrheim Eugenia V. Serova Moscow Halle/Saale Klaus Frohberg Bonn Joachim von Braun January 2000 x Russia's Agro-food Sector: Towards Truly Functioning Markets Wehrheim, P., E. V. Serova, K. Frohberg, and J. von Braun (eds.) Kluwer Academic Publishers, pp. 1 - 8 SECTION 1 Introduction and Overview Peter Wehrheim, Eugenia V. Serova, Klaus Frohberg, and Joachim von Braun 1. INTRODUCTION This publication takes a close look at the agro-food economy in Russia.

Taschenbuch. Condición: Neu. Neuware - In dieser kurzgefaßten Anleitung werden die klinisch relevanten EKG-Veränderungen übersichtlich und praxisbezogen dargestellt. Anhand plausibler 'Grundregeln' wird am Beispiel vieler Original-EKG-Registrierungen exemplarisch der Weg zur richtigen elektrokardiographischen Diagnose gewiesen. Tabellarische Übersichten mit Leitliniencharakter erleichtern die Befundinterpretation. Knappe stichwortartige Texte bringen die EKG-Befunde auf den Punkt. Das Buch empfiehlt sich für alle im Not- und Nachtdienst mit akuten EKG-Befunden konfrontierten Ärzte. Es ist zudem ein hilfreicher Leitfaden für Studenten im praktischen Jahr, Ärzte im Praktikum sowie Assistenzärzte der inneren Medizin und angrenzender Fachgebiete.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Scattering theory is, roughly speaking, perturbation theory of self-adjoint operators on the (absolutely) continuous spectrum. It has its origin in mathematical problems of quantum mechanics and is intimately related to the theory of partial differential equations. Some recently solved problems, such as asymptotic completeness for the Schrödinger operator with long-range and multiparticle potentials, as well as open problems, are discussed. We construct also potentials for which asymptotic completeness is violated. This corresponds to a new class of asymptotic solutions of the time-dependent Schrödinger equation. Special attention is paid to the properties of the scattering matrix, which is the main observable of the theory. The book is addressed to readers interested in a deeper study of the subject. 192 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book systematically develops the nonlinear potential theory connected with the weighted Sobolev space Wm,pw( ), where the weight usually belongs to Muckenhoupt's class of Ap weights. These spaces occur as solutions spaces for degenerate elliptic partial differential equations. The Sobolev space theory covers results concerning approximation, extension, and interpolation, Sobolev and Poincare inequalities, Maz'ya type embedding theorems, and isoperimetric inequalities. In the chapter devoted to potential theory, several weighted capacities are investigated. Moreover, 'Kellogg lemmas' are established for various concepts of thinness. Applications of potential theory to weighted Sobolev spaces include quasi continuity of Sobolev functions, Poincare inequalities, and spectral synthesis theorems. 196 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As this Preface is being written, the twentieth century is coming to an end. Historians may perhaps come to refer to it as the century of information, just as its predecessor is associated with the process of industrialisation. Successive technological developments such as the telephone, radio, television, computers and the Internet have had profound effects on the way we live. We can see pic tures of the surface of Mars or the early shape of the Universe. The contents of a whole shelf-load of library books can be compressed onto an almost weight less piece of plastic. Billions of people can watch the same football match, or can keep in instant touch with friends around the world without leaving home. In short, massive amounts of information can now be stored, transmitted and processed, with surprising speed, accuracy and economy. Of course, these developments do not happen without some theoretical ba sis, and as is so often the case, much of this is provided by mathematics. Many of the first mathematical advances in this area were made in the mid-twentieth century by engineers, often relying on intuition and experience rather than a deep theoretical knowledge to lead them to their discoveries. Soon the math ematicians, delighted to see new applications for their subject, joined in and developed the engineers' practical examples into wide-ranging theories, com plete with definitions, theorems and proofs. 228 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this important text, Malcolm Payne shows how team members in care services can use networking and teambuilding to strengthen their practice by being open to work with wider networks of agencies, professionals and service users. He brings traditional team development up-to-date, including perspectives from research, from management ideas and from professional writings. Each chapter contains a concise account of new ideas in teamwork, practical guidance on teambuilding and teambuilding activities for team members. 288 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This fascinating and thought-provoking book provides much-needed philosophical background for counsellors, therapists and healthcare workers looking for broader, deeper foundations in the struggle to help and make sense of others. While examining the best among twentieth-century philosophy it shows the wealth of inspiration of earlier centuries, and demonstrates with remarkable clarity the way in which the ideas of, and the relations between, these philosophers can inspire, inform and underpin much of counselling and psychotherapy.The author ties the philosophies with practice in a pragmatic and exercise-based way, making it an excellent source for training courses. Each chapter is headed with 'key points' and their application to counselling and psychotherapy, and ends with practical questions, exercises and a detailed bibliography, including extensive listing of relevant websites. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -These arethe proceedingsof the Fourth InternationalWorkshopon Cooperative Information Agents, held in Boston Massachusetts, USA, July 7-9, 2000. Cooperative information agent research and development focused originally onaccessingmultiple,heterogeneous,anddistributedinformationsources. Ga- ingaccesstothesesystems,throughInternetsearchengines,applica tionprogram interfaces, wrappers, and web-based screens has been an important focus of - operative intelligent agents. Research has also focused on the integration of this information into a coherent model that combined data and knowledge from the multiple sources. Finally, this information is disseminated to a wide audience, giving rise to issues such as data quality, information pedigree, source reliability, information security, personal privacy, and information value. Research in - operative information agents has expanded to include agent negotiation, agent communities, agent mobility, as well as agent collaboration for information d- covery in constrained environments. TheinterdisciplinaryCIAworkshopseriesencompassesa widevarietyoft- ics dealing with cooperative information agents. All workshop proceedings have been published by Springer as Lecture Notes in Arti cial Intelligence, Volumes 1202 (1997), 1435 (1998), and 1652 (1999), respectively. This year, the theme of the CIA workshop was ''The Future of Information Agents in Cyberspace', a very tting topic as the use of agents for information gathering, negotiation, correlation, fusion, and dissemination becomes ever more prevalent. We noted a marked trend in CIA 2000 towards addressing issues related to communities of agents that: (1) negotiate for information resources, (2) build robust ontologies to enhance search capabilities, (3) communicate for planning and problem so- ing, (4) learn and evolve based on their experiences, and (5) assume increasing degrees of autonomy in the control of complex systems. 684 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -New technologies and the growing flow of information create new conditions for individuals who use these technologies in the work place. The existence and application of modern IT systems can result in new forms of work, tasks that have actually emerged as a result of modern computer and other systems. This second Work Life 2000 Yearbook contains the proceedings of European workshops, organised by the Swedish National Institute for Working Life. These workshops illuminate many different aspects of working life in many nations. 272 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In [Hardy and Williams, 1986] the authors exploited a very simple idea to obtain a linear congruence involving class numbers of imaginary quadratic fields modulo a certain power of 2. Their congruence provided a unified setting for many congruences proved previously by other authors using various means. The Hardy-Williams idea was as follows. Let d be the discriminant of a quadratic field. Suppose that d is odd and let d = PIP2 . . Pn be its unique decomposition into prime discriminants. Then, for any positive integer k coprime with d, the congruence holds trivially as each Legendre-Jacobi-Kronecker symbol (~) has the value + 1 or -1. Expanding this product gives ~ eld e:=l (mod4) where e runs through the positive and negative divisors of d and v (e) denotes the number of distinct prime factors of e. Summing this congruence for o k Idl/8, gcd(k, d) = 1, gives ~ (-It(e) ~ (~) =:O(mod2n). eld o 276 pp. Englisch.