Springer new york aug 2016 (979 resultados)

Taschenbuch. Condición: Neu. Neuware -Pattern recognition has its origins in engineering, whereas machine learning grew out of computer science. However, these activities can be viewed as two facets of the same field, and together they have undergone substantial development over the past ten years. In particular, Bayesian methods have grown from a specialist niche to become mainstream, while graphical models have emerged as a general framework for describing and applying probabilistic models. Also, the practical applicability of Bayesian methods has been greatly enhanced through the development of a range of approximate inference algorithms such as variational Bayes and expectation pro- gation. Similarly, new models based on kernels have had significant impact on both algorithms and applications. This new textbook reacts these recent developments while providing a comprehensive introduction to the fields of pattern recognition and machine learning. It is aimed at advanced undergraduates or first year PhD students, as wellas researchers and practitioners, and assumes no previous knowledge of pattern recognition or - chine learning concepts. Knowledge of multivariate calculus and basic linear algebra is required, and some familiarity with probabilities would be helpful though not essential as the book includes a self-contained introduction to basic probability theory.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 760 pp. Englisch. …

Taschenbuch. Condición: Neu. Neuware - Principles and Practice of Interventional Pulmonology provides a comprehensive text covering all aspects of Interventional Pulmonology. Providing both pathophysiologic background as well as illustrated and clear instruction on how procedures ought to be performed, this text will be of great value to interventional pulmonologists, thoracic surgeons, surgical oncologists, and interventional radiologists.…

Taschenbuch. Condición: Neu. Neuware - The complex intersecting of genetic, biological, and environmental factors can make intellectual impairments difficult for clinicians to assess and treat. When such comorbid conditions as substance abuse or bipolar disorder are part of the equation, so are increased risks for clinical uncertainties and therapeutic dead-ends.The Handbook of Psychopathology in Intellectual Disability reflects the diversity of its subject in prevalence and presentation, testing methods and treatment options. Besides focusing on specific pathologies as they affect the course of intellectual disability (ID), its coverage spans the field from in-depth analyses of psychosocial aspects of ID to promising new findings in genetics and the ongoing challenge of providing personalized care tailored to individual client needs. Expert contributors bridge gaps between the evidence base and best practices and improved policy for maximum utility. In addition, chapters are written to benefit the widest variety of professionals treating clients with ID across disciplines. Key areas featured in the Handbook include:General issues and assessment methods.Core etiological approaches, including neuroimaging.Comorbid psychopathology, including mood, anxiety, and personality disorders.Common clinical conditions, such as ADHD, autism, and behavior problems.Medical and psychological interventions as well as community and inpatient services.Future directions in research and evidence-based practices.The Handbook of Psychopathology in Intellectual Disability is an essential reference for researchers, professors, and graduate students as well as clinicians and other scientist-practitioners in clinical psychology, psychiatry, social work, rehabilitation medicine, public health, and neuropsychology.…

Taschenbuch. Condición: Neu. Neuware -The International Handbook of Research on Teachers and Teaching provides a fresh look at the ever changing nature of the teaching profession throughout the world. This collection of over 70 original articles addresses a wide range of issues that are relevant for understanding the present educational climate in which the accountability of teachers and the standardized testing of students have become dominant.The international collection of authors brings to the handbook a breadth of knowledge and experience about the teaching profession and a wealth of material across a number of comparative dimensions, such as between developed and developing countries and between Eastern and Western cultures. In addition, many articles address the emerging challenges to education and to the lives of teachers which are brought about by the globalization trends of the 21st Century.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The word ''terraforming'' conjures up many exotic images and p- hapsevenwildemotions,butatitscoreitencapsulatestheideathat worldscanbechangedbydirecthumanaction.Theultimateaimof terraforming is to alter a hostile planetary environment into one that is Earth-like, and eventually upon the surface of the new and vibrant world that you or I could walk freely about and explore. It is not entirely clear that this high goal of terraforming can ever be achieved, however, and consequently throughout much of thisbooktheterraformingideasthatarediscussedwillapplytothe goal of making just some fraction of a world habitable. In other cases,theterraformingdescribedmightbeaimedatmakingaworld habitablenotforhumansbutforsomepotentialfoodsourcethat,of course, could be consumed by humans. The many icy moons that reside within the Solar System, for example, may never be ideal locationsforhumanhabitation,buttheypresentthegreatpotential for conversion into enormous hydroponic food-producing centers. The idea of transforming alien worlds has long been a literary backdrop for science fiction writers, and many a make-believe planet has succumbed to the actions of direct manipulation and the indomitable grinding of colossal machines. Indeed, there is something both liberating and humbling about the notion of tra- forming another world; it is the quintessential eucatastrophy espoused by J. R. R. Tolkien, the catastrophe that ultimately brings about a better world. When oxygen was first copiously produced by cyanobacterial activity on the Earth some three billion years ago, it was an act of extreme chemical pollution and a eucatastrophy. The original life-nurturing atmosphere was (eventually) changed f- ever, but an atmosphere that could support advanced life forms came about. 304 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Making a robot that looks and behaves like a human being has been the subject of many popular science fiction movies and books. Although the development of such a robot facesmanychallenges,themakingofavirtualhumanhaslongbeenpotentiallypossible. With recent advances in various key technologies related to hardware and software, the making of humanlike robots is increasingly becoming an engineering reality. Development of the required hardware that can perform humanlike functions in a lifelike manner has benefitted greatly from development in such technologies as biologically inspired materials, artificial intelligence, artificial vision, and many others. Producing a humanlike robot that makes body and facial expressions, communicates verbally using extensive vocabulary, and interprets speech with high accuracy is ext- mely complicated to engineer. Advances in voice recognition and speech synthesis are increasingly improving communication capabilities. In our daily life we encounter such innovations when we call the telephone operators of most companies today. As robotics technology continues to improve we are approaching the point where, on seeing such a robot, we will respond with ''Wow, this robot looks unbelievably real!'' just like the reaction to an artificial flower. The accelerating pace of advances in related fields suggests that the emergence of humanlike robots that become part of our daily life seems to be imminent. These robots are expected to raise ethical concerns and may also raise many complex questions related to their interaction with humans. 188 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Written by William Sheehan, a noted historian of astronomy, and Christopher J. Conselice, a professional astronomer specializing in galaxies in the early universe, this book tells the story of how astronomers have pieced together what is known about the vast and complicated systems of stars and dust known as galaxies. The first galaxies appeared as violently disturbed exotic objects when the Universe was only a few 100 million years old. From that tortured beginning, they have evolved though processes of accretion, merging and star formation into the majestic spirals and massive ellipticals that dominate our local part of the Universe. This of course includes the Milky Way, to which the Sun and Solar System belong; it is our galactic home, and the only galaxy we will ever know from the inside. Sheehan and Conselice show how astronomers' understanding has grown from the early catalogs of Charles Messier and William Herschel; developed through the pioneering efforts of astronomers like E.E. Barnard, V.M. Slipher, Henrietta Leavitt, Edwin Hubble and W.W. Morgan; and finally is reaching fruition in cutting-edge research with state-of-the-art instruments such as the Hubble Space Telescope that can see back to nearly the beginning of the Universe. By combining archival research that reveals fascinating details about the personalities, rivalries and insights of the astronomers who created extragalactic astronomy with the latest data gleaned from a host of observations, the authors provide a view of galaxies - and their place in our understanding of the Universe - as they have never been seen before. 400 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This is the story of the astronomer Milton La Salle Humason, whose career was integral to developing our understanding of stellar and universal evolution and who helped to build the analytical basis for the work of such notable astronomers and astrophysicists as Paul Merrill, Walter Adams, Alfred Joy, Frederick Seares, Fritz Zwicky, Walter Baade and Edwin Hubble. Humason's unlikely story began on the shores of the Mississippi River in Winona, Minnesota, in 1891 and led to the foot of Mount Wilson outside Los Angeles, California, twelve years later. It is there where he first attended summer camp in 1903 and was captivated by its surroundings. The mountain would become the backdrop for his life and career over the next six decades as he helped first build George Ellery Hale's observatory on the summit and then rose to become one of that institution's leading figures through the first half of the twentieth century. The story chronicles Humason's life on Mount Wilson, from his first trip to the mountain to his days as a muleskinner, leading teams of mules hauling supplies to the summit during the construction of the observatory, and follows him through his extraordinary career in spectroscopy, working beside Edwin Hubble as the two helped to reconstruct our concept of the universe. A patient, knowledgeable and persistent observer, Humason was later awarded an honorary doctorate for his work, despite having no formal education beyond the eighth grade. His skill at the telescope is legendary. During his career he photographed the spectra of stars, galaxies and other objects many thousands of times fainter than can be seen with the naked eye and pushed the boundary of the known universe deeper into space than any before him. His work, which included assisting in the formulation of Hubble's Law of redshifts, helped to set the field of cosmology solidly on its foundation. Milton Humason was one of the most charismatic characters in science during the first half of the 20th century. Uneducated, streetwise, moonshining, roguish, humble and thoroughly down to earth, he rose by sheer chance, innate ability and incredible will to become the leading deep space observer of his day. 'The Renaissance man of Mount Wilson,' as Harlow Shapley once referred to him, Humason's extraordinary life reminds us that passion and purpose may find us at any moment. 244 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mathematics in the Real World is a self-contained, accessible introduction to the world of mathematics for non-technical majors. With a focus on everyday applications and context, the topics in this textbook build in difficulty and are presented sequentially, starting with a brief review of sets and numbers followed by an introduction to elementary statistics, models, and graph theory. Data and identification numbers are then covered, providing the pathway to voting and finance. Each subject is covered in a concise and clear fashion through the use of real-world applications and the introduction of relevant terminology. Many sample problems - both writing exercises and multiple-choice questions - are included to help develop students' level of understanding and to offer a variety of options to instructors.Covering six major units and outlining a one-semester course, Mathematics in the Real World is aimed at undergraduate liberal art students fulfilling the mathematics requirement in their degree program. This introductory text will be an excellent resource for such courses, and will show students where mathematics arises in their everyday lives. 288 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text explores the many transformations that the mathematical proof has undergone from its inception to its versatile, present-day use, considering the advent of high-speed computing machines. Though there are many truths to be discovered in this book, by the end it is clear that there is no formalized approach or standard method of discovery to date. Most of the proofs are discussed in detail with figures and equations accompanying them, allowing both the professional mathematician and those less familiar with mathematics to derive the same joy from reading this book. 284 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The book is divided into two parts. In the first, the reader is taken on an ideal 'world tour' of many wonderful and enigmatic places in almost every continent, in search of traces of astronomical knowledge and lore of the sky. In the second part, Giulio Magli uses the elements presented in the tour to show that the fundamental idea which led to the construction of the astronomically-related giant monuments was the foundation of power, a foundation which was exploited by 'replicating' the sky. A possible interpretive model then emerges that is founded on the relationship the ancients had with 'nature', in the sense of everything that surrounded them, the cosmos. The numerous monumental astronomically aligned structures of the past then become interpretable as acts of will, expressions of power on the part of those who held it; the will to replicate the heavenly plane here on earth and to build sacred landscapes.Finally, having formulated his hypothesis, Professor Magli returns to visit one specific place in detail, searching for proof. This in-depth examination studies the most compelling, the most intensively studied, the most famous and, until recently, the most misunderstood sacred landscape on the planet - Giza, in Egypt. The archaeoastronomical analysis of the orientation of the Giza pyramids leads to the hypothesis that the pyramids of Cheops and Chephren belong to the same construction project. 492 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book goes beyond the basics of a first course in calculus to reveal the power and richness of the subject. Standard topics from calculus - such as the real numbers, differentiation and integration, mean value theorems, the exponential function - are reviewed and elucidated before digging into a deeper exploration of theory and applications, such as the AGM inequality, convexity, the art of integration, and explicit formulas for pi. Further topics and examples are introduced through a plethora of exercises that both challenge and delight the reader. While the reader is thereby exposed to the many threads of calculus, the coherence of the subject is preserved throughout by an emphasis on patterns of development, of proof and argumentation, and of generalization.More Calculus of a Single Variable is suitable as a text for a course in advanced calculus, as a supplementary text for courses in analysis, and for self-study by students, instructors, and, indeed, all connoisseurs of ingenious calculations. 428 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent books have raised the public consciousness about the dangers of global warming and climate change. This book is intended to convey the message that there is a solution. The solution is the rapid development of hydrogen fusion energy. This energy source is inexhaustible and, although achieving fusion energy is difficult, the progress made in the past two decades has been remarkable. The physics issues are now understood well enough that serious engineering can begin.The book starts with a summary of climate change and energy sources, trying to give a concise, clear, impartial picture of the facts, separate from conjecture and sensationalism. Controlled fusion -- the difficult problems and ingenious solutions -- is then explained using many new concepts.The bottom line -- what has yet to be done, how long it will take, and how much it will cost -- may surprise you.Francis F. Chen's career in plasma has extended over five decades. His textbook Introduction to Plasma Physics has been used worldwide continuously since 1974. He is the only physicist who has published significantly in both experiment and theory and on both magnetic fusion and laser fusion. As an outdoorsman and runner, he is deeply concerned about the environment. Currently he enjoys bird photography and is a member of the Audubon Society. 452 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text presents the Eulerian numbers in the context of modern enumerative, algebraic, and geometric combinatorics. The book first studies Eulerian numbers from a purely combinatorial point of view, then embarks on a tour of how these numbers arise in the study of hyperplane arrangements, polytopes, and simplicial complexes. Some topics include a thorough discussion of gamma-nonnegativity and real-rootedness for Eulerian polynomials, as well as the weak order and the shard intersection order of the symmetric group.The book also includes a parallel story of Catalan combinatorics, wherein the Eulerian numbers are replaced with Narayana numbers. Again there is a progression from combinatorics to geometry, including discussion of the associahedron and the lattice of noncrossing partitions.The final chapters discuss how both the Eulerian and Narayana numbers have analogues in any finite Coxeter group, with many of the same enumerative and geometric properties.Thereare four supplemental chapters throughout, which survey more advanced topics, including some open problems in combinatorial topology. This textbook will serve a resource for experts in the field as well as for graduate students and others hoping to learn aboutthese topicsfor the first time. 476 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text on geometry is devoted to various central geometrical topics including: graphs of functions, transformations, (non-)Euclidean geometries, curves and surfaces as well as their applications in a variety of disciplines. This book presents elementary methods for analytical modeling and demonstrates the potential for symbolic computational tools to support the development of analytical solutions. The author systematically examines several powerful tools of MATLAB® including 2D and 3D animation of geometric images with shadows and colors and transformations using matrices. With over 150 stimulating exercises and problems, this text integrates traditional differential and non-Euclidean geometries with more current computer systems in a practical and user-friendly format. This text is an excellent classroom resource or self-study reference for undergraduate students in a variety of disciplines. 468 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This engineering dynamics textbook is aimed at beginning graduate students in mechanical engineering and other related engineering disciplines who need training in dynamics as applied to engineering mechanisms. It introduces the formal mathematical development of Lagrangian mechanics (and its corollaries), while solving numerous engineering applications. The author's goal is to instill an understanding of the basic physics required for engineering dynamics, while providing a recipe (algorithm) for the simulation of engineering mechanisms such as robots. The book will be reasonably self-contained so that the practicing engineer interested in this area can also make use of it. This book is made accessible to the widest possible audience by numerous, solved examples and diagrams that apply the principles to real engineering applications.- Provides an applied textbook for intermediate/advanced engineering dynamics courses;- Discusses Lagrangian mechanics in the context of numerous engineering applications;- Includes numerous, solved examples, illustrative diagrams and applied exercises in every chapter 284 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Drawing examplesfrom mathematics, physics, chemistry, biology, engineering, economics, medicine, politics, and sports, this book illustrates how nonlinear dynamics plays a vital role in our world. Examples cover a wide range from the spread and possible control of communicable diseases, to the lack of predictability in long-range weather forecasting, to competition between political groups and nations.After an introductorychapter that explores what it means to be nonlinear, the book covers the mathematical conceptssuch as limit cycles, fractals, chaos, bifurcations, and solitons, that will be applied throughout the book. Numerous computer simulations and exercises allow students to explore topics in greater depth using the Maple computer algebra system. The mathematical level of the text assumes prior exposure to ordinary differential equations and familiarity with the wave and diffusion equations.No prior knowledge of Maple is assumed.The book may be used at the undergraduate or graduate level to prepare science and engineering students for problems in the 'real world', or for self-study by practicing scientists and engineers. 396 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contains articles arising from a conference in honour of mathematician-statistician Mikl s Csörgö on the occasion of his 80th birthday, held in Ottawa in July 2012. It comprises research papers and overview articles, which provide a substantial glimpse of the history and state-of-the-art of the field of asymptotic methods in probability and statistics, written by leading experts.The volume consists of twenty articles on topics on limit theorems for self-normalized processes, planar processes, the central limit theorem and laws of large numbers, change-point problems, short and long range dependent time series, applied probability and stochastic processes, and the theory and methods of statistics. It also includes Csörgö's list of publications during more than 50 years, since 1962. 424 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Enhancement cavities are passive optical resonators in which continuous-wave laser radiation or pulses of a frequency comb are coherently overlapped, allowing for a power and intensity scaling of up to several orders of magnitude. A prominent application is the table-top generation of bright, laser-like radiation in spectral regions where direct laser action is inefficient or not available at all, via intracavity nonlinear optical processes. However, to exploit the full capacity of this technique further progress is needed. This thesis covers central problems of enhancement cavities, such as finding limitations in scaling the circulating power, measuring cavity parameters with high accuracy, tailoring transverse modes and coupling out radiation generated in the cavity. Unprecedented intracavity laser powers were demonstrated, surpassing previous results by an order of magnitude. As an application, harmonics of the fundamental 1040-nm radiation up to the 21st order are generated. Besides reporting these fine experimental results, the thesis provides an excellent introduction into the physics of enhancement cavities, supported by more than 140 references. 108 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Optimization is a field important in its own right but is also integral to numerous applied sciences, including operations research, management science, economics, finance and all branches of mathematics-oriented engineering. Constrained optimization models are one of the most widely used mathematical models in operations research and management science.This book gives a modern and well-balanced presentation of the subject, focusing on theory but also including algorithims and examples from various real-world applications. Detailed examples and counter-examples are provided--as are exercises, solutions and helpful hints, and Matlab/Maple supplements. 424 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book, some of the most qualified scientists review different food safety topics, ranging from emerging and reemerging foodborne pathogens, food regulations in the USA, food risk analysis and the most important foodborne pathogens based on food commodities. This book provides the reader with the necessary knowledge to understand some of the complexities of food safety. However, anybody with basic knowledge in microbiology will find in this book additional information related to a variety of food safety topics. 272 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Elliptically Contoured Models in Statistics and Portfolio Theory fully revises the first detailed introduction to the theory of matrix variate elliptically contoured distributions. There are two additional chapters, and all the original chapters of this classic text have been updated. Resources in this book will be valuable for researchers, practitioners, and graduate students in statistics and related fields of finance and engineering. Those interested in multivariate statistical analysis and its application to portfolio theory will find this text immediately useful. In multivariate statistical analysis, elliptical distributions have recently provided an alternative to the normal model. Elliptical distributions have also increased their popularity in finance because of the ability to model heavy tails usually observed in real data. Most of the work, however, is spread out in journals throughout the world and is not easily accessible to the investigators. A noteworthy function of this book is the collection of the most important results on the theory of matrix variate elliptically contoured distributions that were previously only available in the journal-based literature. The content is organized in a unified manner that can serve an a valuable introduction to the subject. 344 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Countless medical researchers over the past century have been occupied by the search for a cure of cancer. So far, they have developed and implemented a wide range of treatment techniques, including surgery, chemo- and radiotherapy, antiangiogenic drugs, small molecule inhibitors, and oncolytic viruses. However, patterns of these treatments' effectiveness remain largely unclear, and a better understanding of how cancer therapies work has become a key research goal. Cancer Treatment in Silico provides the first in-depth study of approaching this understanding by modeling cancer treatments, both mathematically and through computer simulations.The main goal of this book is to help expose students and researchers to in silico methods of studying cancer. It is intended for both the applied mathematics and experimental oncology communities, as mathematical models are playing an increasingly important role to supplement laboratory biology in the fight against cancer. Written at a level that generally requires little technical background, the work will be a valuable resource for scientists and students alike. 244 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In Apoptosis and Cancer: Methods and Protocols, Second Edition, expert researches in the field detail the performance of molecular and cellular biology techniques for studying and detecting the activation of the apoptotic pathway. Chapters focus on assays developed to detect its activation not only in vitro but also in vivo, optimized multiplex analysis, medium- to high-throughput screens, and the cellular process. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Apoptosis and Cancer: Methods and Protocols, Second Edition aids scientists as a stand-alone resource for the execution and analysis of the described protocols and as a reference for the study and detection of apoptosis within and outside the area of cancer research. 220 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume emphasizes new techniques to help understand protein cages and to apply them to a variety of technologies, highlighting the expertise of researchers based on three continents. Protein cages are currently inspiring diverse scientific disciplines and are therefore at the crossroads of extremely widely-scoped research, which is reflected in the detailed chapters of Protein Cages: Methods and Protocols. From nanomaterials studies and iron particles to computational strategies and Atomic Force Microscopy, the chapters herein collectively provide an introduction to the rich world of protein cage research and specific techniques to understand and exploit this fascinating class of proteins. Written in the highly successful Methods in Molecular Biology series format, chapters begin with an introduction to their respective topics, lists of the necessary materials, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Practical and cutting-edge, Protein Cages: Methods and Protocols will help to inspire and further propel the current multi-disciplinary enthusiasm in studying and discovering new applications for protein cages. 200 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents detailed, recently-developed protocols ranging from isolation of nuclei to purification of chromatin regions containing single genes, with a particular focus on some less well-explored aspects of the nucleus. The methods described include new strategies for isolation of nuclei, for purification of cell type-specific nuclei from a mixture, and for rapid isolation and fractionation of nucleoli. For gene delivery into and expression in nuclei, a novel gentle approach using gold nanowires is presented. As the concentration and localization of water and ions are crucial for macromolecular interactions in the nucleus, a new approach to measure these parameters by correlative optical and cryo-electron microscopy is described. The Nucleus, Second Edition presents methods and software for high-throughput quantitative analysis of 3D fluorescence microscopy images, for quantification of the formation of amyloid fibrils in the nucleus, and for quantitative analysis of chromosome territory localization. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, The Nucleus, Second Edition seeks to serve both professionals and novices with its well-honed methods for the study of the nucleus. 252 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This second edition of Mathematical Methods in the Robust Control of Linear Stochastic Systems includes a large number of recent results in the control of linear stochastic systems. More specifically, the new results presented are: - A unified and abstract framework for Riccati type equations arising in the stochastic control- Stability and control problems for systems perturbed by homogeneous Markov processes with infinite number of states- Mixed H2 / H control problem and numerical procedures- Linear differential equations with positive evolution on ordered Banach spaces with applications for stochastic systems including both multiplicative white noise and Markovian jumps represented by a Markov chain with countable infinite set of states- Kalman filtering for stochastic systems subject both to state dependent noise and Markovian jumps- H reduced order filters for stochastic systems The book will appeal to graduate students, researchers in advanced control engineering, finance, mathematical systems theory, applied probability and stochastic processes, and numerical analysis.From Reviews of the First Edition: This book is concerned with robust control of stochastic systems. One of the main features is its coverage of jump Markovian systems. . Overall, this book presents results taking into consideration both white noise and Markov chain perturbations. It is clearly written and should be useful for people working in applied mathematics and in control and systems theory. The references cited provide further reading sources. (George Yin, Mathematical Reviews, Issue 2007 m)This book considers linear time varying stochastic systems, subjected to white noise disturbances and system parameter Markovian jumping, in the context of optimal control . robust stabilization, and disturbance attenuation. . The material presented in the book is organized in seven chapters. . The book is very well written and organized. . is a valuable reference for all researchers and graduate students in applied mathematics and control engineering interested in linear stochastic time varying control systems with Markovian parameter jumping and white noise disturbances.(Zoran Gajic, SIAM Review, Vol. 49 (3), 2007) 460 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume reviews the theory and simulation methods of stochastic kinetics by integrating historical and recent perspectives, presents applications, mostly in the context of systems biology and also in combustion theory. In recent years, due to the development in experimental techniques, such as optical imaging, single cell analysis, and fluorescence spectroscopy, biochemical kinetic data inside single living cells have increasingly been available. The emergence of systems biology brought renaissance in the application of stochastic kinetic methods. 176 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This compact monograph is focused on disturbance attenuation in nonsmooth dynamic systems, developing an H approach in the nonsmooth setting. Similar to the standard nonlinear H approach, the proposed nonsmooth design guarantees both the internal asymptotic stability of a nominal closed-loop system and the dissipativity inequality, which states that the size of an error signal is uniformly bounded with respect to the worst-case size of an external disturbance signal. This guarantee is achieved by constructing an energy or storage function that satisfies the dissipativity inequality and is then utilized as a Lyapunov function to ensure the internal stability requirements.Advanced H Control is unique in the literature for its treatment of disturbance attenuation in nonsmooth systems. It synthesizes various tools, including Hamilton-Jacobi-Isaacs partial differential inequalities as well as Linear Matrix Inequalities. Along with the finite-dimensional treatment, the synthesis is extended to infinite-dimensional setting, involving time-delay and distributed parameter systems. To help illustrate this synthesis, the book focuses on electromechanical applications with nonsmooth phenomena caused by dry friction, backlash, and sampled-data measurements. Special attention is devoted to implementation issues.Requiring familiarity with nonlinear systems theory, this book will be accessible to graduate students interested in systems analysis and design, and is a welcome addition to the literature for researchers and practitioners in these areas. 232 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -These contributions, written by the foremost international researchers and practitioners of Genetic Programming (GP), explore the synergy between theoretical and empirical results on real-world problems, producing a comprehensive view of the state of the art in GP. Topics in this volume include: evolutionary constraints, relaxation of selection mechanisms, diversity preservation strategies, flexing fitness evaluation, evolution in dynamic environments, multi-objective and multi-modal selection, foundations of evolvability, evolvable and adaptive evolutionary operators, foundation of injecting expert knowledge in evolutionary search, analysis of problem difficulty and required GP algorithm complexity, foundations in running GP on the cloud - communication, cooperation, flexible implementation, and ensemble methods. Additional focal points for GP symbolic regression are: (1) The need to guarantee convergence to solutions in the function discovery mode; (2) Issues on model validation; (3) The need for model analysis workflows for insight generation based on generated GP solutions - model exploration, visualization, variable selection, dimensionality analysis; (4) Issues in combining different types of data. Readers will discover large-scale, real-world applications of GP to a variety of problem domains via in-depth presentations of the latest and most significant results. 244 pp. Englisch.…