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Añadir al carritoCondición: New. pp. 396.
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Añadir al carritoCondición: New. pp. 396 130 Illus. (5 Col.).
Idioma: Inglés
Publicado por Geological Society of London, 2013
ISBN 10: 1862393494 ISBN 13: 9781862393493
Librería: Utah Book and Magazine, Salt Lake City Utah, UT, Estados Unidos de America
Original o primera edición
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Añadir al carritoHardcover. Condición: New. 1st Edition. BOOK IS BRAND NEW IN ORIGINQAL SHRINK WRAP, Condition of Book NEW.
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Añadir al carritoCondición: Sehr gut. Zustand: Sehr gut | Seiten: 396 | Sprache: Englisch | Produktart: Bücher | The last decade has seen the confluence of several enabling technologies that have allowed protein crystallographic methods to live up to their true potential. Taken together, the numerous recent advances have made it possible to tackle difficult biological targets with a high probability of success: intact bacterial ribosomes have been structurally elucidated, as well as eukaryotic trans-membrane proteins like the potassium channel and GPCRs. It is now possible for medicinal chemists to have access to structural information on their latest small molecule candidates bound to the therapeutic target within days of compound synthesis, allowing structure guided ligand optimization to occur in "real time". Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads. Written in the successful Methods in Molecular Biology¿ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Structure-Based Drug Discovery aims to provide scientists interested in adding SBDD to their arsenal of drug discovery methods with well-honed, up-to-date methodologies.
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Añadir al carritoCondición: New. Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads. Editor(s): Tari, Leslie W. Series: Methods in Molecular Biology. Num Pages: 385 pages, 19 black & white tables, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 262 x 180 x 27. Weight in Grams: 900. . 2012. 2012. Hardback. . . . .
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Añadir al carritoHardcover. Condición: Brand New. 1st edition. 385 pages. 10.50x7.00x1.25 inches. In Stock.
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Añadir al carritoCondición: New. Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads. Editor(s): Tari, Leslie W. Series: Methods in Molecular Biology. Num Pages: 385 pages, 19 black & white tables, biography. BIC Classification: MMG. Category: (P) Professional & Vocational. Dimension: 262 x 180 x 27. Weight in Grams: 900. . 2012. 2012. Hardback. . . . . Books ship from the US and Ireland.
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Añadir al carritoCondición: New. 2016. Softcover reprint of the original 1st ed. 2012. paperback. . . . . .
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Añadir al carritoTaschenbuch. Condición: Neu. Structure-Based Drug Discovery | Leslie W. Tari | Taschenbuch | ix | Englisch | 2016 | Humana | EAN 9781493961375 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Añadir al carritoPaperback. Condición: Brand New. reprint edition. 385 pages. 10.00x7.01x0.93 inches. In Stock.
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Añadir al carritoCondición: New. 2016. Softcover reprint of the original 1st ed. 2012. paperback. . . . . . Books ship from the US and Ireland.
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Idioma: Inglés
Publicado por Geological Society of London, 2013
ISBN 10: 1862393494 ISBN 13: 9781862393493
Librería: Joseph Burridge Books, Dagenham, Reino Unido
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Añadir al carritoHardcover. Condición: New. The main focus of the book is the geological and geophysical interpretation of sedimentary basins along the South, Central and North Atlantic conjugate margins, but concepts derived from physical models, outcrop analogues and present-day margins are also discussed in some chapters. There is an encompassing description of several conjugate margins worldwide, based on recent geophysical and geological datasets. An overview of important aspects related to the geodynamic development and petroleum geology of Atlantic-type sedimentary basins is also included. Several chapters analyse genetic mechanisms and break-up processes associated with rift-phase structures and salt tectonics, providing a full description of conjugate margin basins based on deep seismic profiles and potential field methods.
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
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Añadir al carritoBuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The last decade has seen the confluence of several enabling technologies that have allowed protein crystallographic methods to live up to their true potential. Taken together, the numerous recent advances have made it possible to tackle difficult biological targets with a high probability of success: intact bacterial ribosomes have been structurally elucidated, as well as eukaryotic trans-membrane proteins like the potassium channel and GPCRs. It is now possible for medicinal chemists to have access to structural information on their latest small molecule candidates bound to the therapeutic target within days of compound synthesis, allowing structure guided ligand optimization to occur in 'real time'. Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads. Written in the successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Structure-Based Drug Discovery aims to provide scientists interested in adding SBDD to their arsenal of drug discovery methods with well-honed, up-to-date methodologies. 396 pp. Englisch.
Librería: moluna, Greven, Alemania
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Añadir al carritoGebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes cutting-edge methods and protocolsProvides step-by-step detail essential for reproducible resultsContains key notes and implementation advice from the expertsThe last decade has seen the confluence of several enabling te.
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Añadir al carritoBuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The last decade has seen the confluence of several enabling technologies that have allowed protein crystallographic methods to live up to their true potential. Taken together, the numerous recent advances have made it possible to tackle difficult biological targets with a high probability of success: intact bacterial ribosomes have been structurally elucidated, as well as eukaryotic trans-membrane proteins like the potassium channel and GPCRs. It is now possible for medicinal chemists to have access to structural information on their latest small molecule candidates bound to the therapeutic target within days of compound synthesis, allowing structure guided ligand optimization to occur in 'real time'. Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads. Written in the successful Methods in Molecular Biology¿ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, Structure-Based Drug Discovery aims to provide scientists interested in adding SBDD to their arsenal of drug discovery methods with well-honed, up-to-date methodologies.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 396 pp. Englisch.
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Añadir al carritoBuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The last decade has seen the confluence of several enabling technologies that have allowed protein crystallographic methods to live up to their true potential. Taken together, the numerous recent advances have made it possible to tackle difficult biological targets with a high probability of success: intact bacterial ribosomes have been structurally elucidated, as well as eukaryotic trans-membrane proteins like the potassium channel and GPCRs. It is now possible for medicinal chemists to have access to structural information on their latest small molecule candidates bound to the therapeutic target within days of compound synthesis, allowing structure guided ligand optimization to occur in 'real time'. Structure-Based Drug Discovery presents an array of methods used to generate crystal structures of biological macromolecules, how to leverage the structural information to design novel ligands anew, and how to iteratively optimize hits and convert them to leads. Written in the successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Structure-Based Drug Discovery aims to provide scientists interested in adding SBDD to their arsenal of drug discovery methods with well-honed, up-to-date methodologies.
Librería: moluna, Greven, Alemania
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Añadir al carritoCondición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Includes cutting-edge methods and protocolsProvides step-by-step detail essential for reproducible resultsContains key notes and implementation advice from the expertsThe last decade has seen the confluence of several enabling te.