Filtrar la búsqueda

  • Libros (37)

a

Intervalo de precios personalizado (EUR)

a

S j berkhout (37 resultados)

Autor: 
Refinar con la Búsqueda avanzada
  • Idioma: Inglés

    Editorial: Pearson, 2011

    • Tapa blanda

    Librería: Chapter 1, Johannesburg, GAU, Sur AfricaChapter 1

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado - Aceptable

    EUR 32,36

    Envío por EUR 25,00 
    Se envía de Sur Africa a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Añadir al carrito

    Paperback. Condición: Good. 2nd Impression.The wraps are rubbed and marked. edge worn.interior clean. Due to weight postal adjustments may be required. Ek. Our orders are shipped using tracked courier delivery services.

  • Más imágenes

    Idioma: Holandés

    Editorial: Edu'Actief, 2006

    9060537289 / 9789060537282

    • Tapa dura

    Librería: Bookbot, Prague, Republica ChecaBookbot

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado - Excelente

    EUR 32,09

    Envío por EUR 14,99 
    Se envía de Republica Checa a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Hardcover. Condición: Fine. Leichte Gebrauchsspuren.

  • Editorial: Breda, Koninklijke Militaire Academie, 1898., 1898

    • Tapa dura
    • Primera edición

    Librería: Librarium of The Hague, The Hague, HolandaLibrarium of The Hague

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado

    EUR 27,00

    Envío por EUR 35,00 
    Se envía de Holanda a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Añadir al carrito

    Hardcover. 1st Edition. Royal octavo. Pp. 180; xviii, Appendix of tables, some folding, bound at end. HARDCOVER, bound in the original publisher's blue cloth and printed boards, old military institutional stamps to cover and title-page, old bookplate inside cover. In a very good condition. ~ FIRST EDITION. Text volume only, without the atlas. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (ilustrador).…

  • Más imágenes

    Editorial: Breda, Koninklijke Militaire Academie, 1898., 1898

    • Tapa dura
    • Primera edición

    Librería: Librarium of The Hague, The Hague, HolandaLibrarium of The Hague

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado

    EUR 27,00

    Envío por EUR 35,00 
    Se envía de Holanda a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Añadir al carrito

    Hardcover. 1st Edition. Royal octavo. Pp. 315. Plus 20 (of 21) lithographic plates with numerous figures. HARDCOVER, bound in the original publisher's blue full cloth, bit marked, large gilt lettering and decorations, cloth inner hinges, silken endpapers, neat contemporary signature to first blank; old institutional stamp to verso of title. In a very good condition. ~ FIRST EDITION. Lacks one plate which is provided herewith in laser facsimile. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (ilustrador). …

  • Idioma: Inglés

    Editorial: Springer, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura

    Librería: GreatBookPrices, Columbia, MD, Estados Unidos de AmericaGreatBookPrices

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 124,07

    Envío por EUR 2,37 
    Se envía dentro de Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Condición: New.

  • Idioma: Inglés

    Editorial: Springer, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura

    Librería: GreatBookPricesUK, Woodford Green, Reino UnidoGreatBookPricesUK

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 123,62

    Envío por EUR 17,98 
    Se envía de Reino Unido a Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Condición: New.

  • Idioma: Inglés

    Editorial: Kluwer Academic Publishers, 1998

    0792352068 / 9780792352068

    • Tapa blanda

    Librería: Kennys Bookshop and Art Galleries Ltd., Galway, GY, IrlandaKennys Bookshop and Art Galleries Ltd.

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 133,80

    Envío por EUR 9,50 
    Se envía de Irlanda a Estados Unidos de America

    Cantidad disponible: 15 disponibles

    Condición: New. As we reach the end of the 20th century, the question of how to meet human needs and preferences while safeguarding the global environment is a concern facing humanity. This book reflects thinking on the necessary concepts, tools and instruments that are likely to help producers, consumers and governments to adjust their policies and practices. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RN. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 240 x 160 x 19. Weight in Grams: 516. . 1998. Softcover reprint of the original 1st ed. 1998. Paperback. . . . . …

  • Idioma: Inglés

    Editorial: Kluwer Academic Publishers, 1998

    0792351533 / 9780792351535

    • Tapa dura

    Librería: Kennys Bookshop and Art Galleries Ltd., Galway, GY, IrlandaKennys Bookshop and Art Galleries Ltd.

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 136,10

    Envío por EUR 9,50 
    Se envía de Irlanda a Estados Unidos de America

    Cantidad disponible: 15 disponibles

    Condición: New. Reflects the state of the art of thinking on the necessary concepts, tools and instruments likely to help producers, consumers and governments to adjust their policies and practices. This book covers theories and concepts, practical approaches and visions of industry and government. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RNK. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 20. Weight in Grams: 691. . 1998. Hardback. . . . . …

  • Idioma: Inglés

    Editorial: Springer, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura

    Librería: Books Puddle, Woodside, NY, Estados Unidos de AmericaBooks Puddle

    Vendedor de 4 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 160,69

    Envío por EUR 3,58 
    Se envía dentro de Estados Unidos de America

    Cantidad disponible: 4 disponibles

    Condición: New. pp. 236.

  • Idioma: Inglés

    Editorial: Springer, 2016

    1493948652 / 9781493948659

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa blanda

    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 124,85

    Envío por EUR 35,00 
    Se envía de Alemania a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.…

  • Idioma: Inglés

    Editorial: Springer, 2016

    1493948652 / 9781493948659

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa blanda

    Librería: Books Puddle, Woodside, NY, Estados Unidos de AmericaBooks Puddle

    Vendedor de 4 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 167,60

    Envío por EUR 3,58 
    Se envía dentro de Estados Unidos de America

    Cantidad disponible: 4 disponibles

    Condición: New. pp. 236.

  • Condición: Nuevo

    EUR 158,72

    Envío por EUR 14,98 
    Se envía de Reino Unido a Estados Unidos de America

    Cantidad disponible: 2 disponibles

    Hardcover. Condición: Brand New. 1st edition. 236 pages. 9.50x6.00x0.75 inches. In Stock.

  • Idioma: Inglés

    Editorial: Kluwer Academic Publishers, 1998

    0792352068 / 9780792352068

    • Tapa blanda

    Librería: Kennys Bookstore, Olney, MD, Estados Unidos de AmericaKennys Bookstore

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 173,65

    Envío por EUR 9,42 
    Se envía dentro de Estados Unidos de America

    Cantidad disponible: 15 disponibles

    Condición: New. As we reach the end of the 20th century, the question of how to meet human needs and preferences while safeguarding the global environment is a concern facing humanity. This book reflects thinking on the necessary concepts, tools and instruments that are likely to help producers, consumers and governments to adjust their policies and practices. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RN. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 240 x 160 x 19. Weight in Grams: 516. . 1998. Softcover reprint of the original 1st ed. 1998. Paperback. . . . . Books ship from the US and Ireland. …

  • Idioma: Inglés

    Editorial: Kluwer Academic Publishers, 1998

    0792351533 / 9780792351535

    • Tapa dura

    Librería: Kennys Bookstore, Olney, MD, Estados Unidos de AmericaKennys Bookstore

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 176,46

    Envío por EUR 9,42 
    Se envía dentro de Estados Unidos de America

    Cantidad disponible: 15 disponibles

    Condición: New. Reflects the state of the art of thinking on the necessary concepts, tools and instruments likely to help producers, consumers and governments to adjust their policies and practices. This book covers theories and concepts, practical approaches and visions of industry and government. Editor(s): Vellinga, Pier; Berkhout, Frans; Gupta, Joyeeta. Series: Environment & Policy. Num Pages: 349 pages, biography. BIC Classification: JPQB; RNK. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 235 x 155 x 20. Weight in Grams: 691. . 1998. Hardback. . . . . Books ship from the US and Ireland. …

  • Idioma: Inglés

    Editorial: Springer New York, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura

    Librería: Buchpark, Trebbin, AlemaniaBuchpark

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado - Excelente

    Oportunidad

    Precio actual: EUR 83,44

    Envío por EUR 105,00 
    Se envía de Alemania a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Condición: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | This book centers  on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals.   Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990¿s. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology.…

  • Condición: Nuevo

    EUR 185,57

    Envío por EUR 11,99 
    Se envía de Reino Unido a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Paperback. Condición: Brand New. reprint edition. 252 pages. 9.25x6.10x0.60 inches. In Stock.

  • Idioma: Inglés

    Editorial: Springer, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura

    Librería: GreatBookPricesUK, Woodford Green, Reino UnidoGreatBookPricesUK

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado - Como Nuevo

    EUR 213,56

    Envío por EUR 17,98 
    Se envía de Reino Unido a Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Condición: As New. Unread book in perfect condition.

  • Idioma: Inglés

    Editorial: Springer, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura

    Librería: Mispah books, Redhill, SURRE, Reino UnidoMispah books

    Vendedor de 4 estrellas
    Contactar con el vendedor

    Condición: Usado - Como Nuevo

    EUR 203,69

    Envío por EUR 29,96 
    Se envía de Reino Unido a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Hardcover. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

  • Idioma: Inglés

    Editorial: Springer, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura

    Librería: GreatBookPrices, Columbia, MD, Estados Unidos de AmericaGreatBookPrices

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado - Como Nuevo

    EUR 238,22

    Envío por EUR 2,37 
    Se envía dentro de Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Condición: As New. Unread book in perfect condition.

  • Idioma: Inglés

    Editorial: Springer, 2016

    1493948652 / 9781493948659

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa blanda

    Librería: Mispah books, Redhill, SURRE, Reino UnidoMispah books

    Vendedor de 4 estrellas
    Contactar con el vendedor

    Condición: Usado - Como Nuevo

    EUR 280,23

    Envío por EUR 29,96 
    Se envía de Reino Unido a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Paperback. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

  • Más imágenes

    Editorial: Breda, Koninklijke Militaire Academie, 1898., 1898

    • Tapa dura
    • Primera edición

    Librería: Librarium of The Hague, The Hague, HolandaLibrarium of The Hague

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado

    EUR 54,00

    Envío por EUR 35,00 
    Se envía de Holanda a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Añadir al carrito

    Hardcover. 1st Edition. Royal octavo. Pp. 315. Plus 21 lithographic plates with numerous figures to each. One plate printed in fine collotype, showing the results of impacts of bullets with body. HARDCOVER, bound in contemporary cloth and marbled boards, very old small shelf tickets, old institutional stamp to half-title and title. In fine condition. ~ FIRST EDITION. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (ilustrador).…

  • Más imágenes

    Editorial: Breda, Koninklijke Militaire Academie, 1900., 1900

    • Tapa dura
    • Primera edición

    Librería: Librarium of The Hague, The Hague, HolandaLibrarium of The Hague

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado

    EUR 58,50

    Envío por EUR 35,00 
    Se envía de Holanda a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Añadir al carrito

    Hardcover. 1st Edition. Crown quarto. Pp. vi, 169, comprising of tables and ballistic data. Plus a suite of 32 lithographic plates bound at end, with numerous illustrations to each plate. HARDCOVER, bound in contemporary calf and boards with the original printed wrappers laid-down, cloth French corners, small old shelf ticket to spine, faded old military institutional stamp to cover; bit shabby, spine bit rubbed in places. In a very good condition. Practically unused, mostly unopened. ~ FIRST EDITION. Very rare. Appendix volume with tables and plates. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (ilustrador).…

  • Más imágenes

    Editorial: Breda, Koninklijke Militaire Academie, 1897., 1897

    • Tapa dura
    • Primera edición

    Librería: Librarium of The Hague, The Hague, HolandaLibrarium of The Hague

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Usado

    EUR 72,00

    Envío por EUR 35,00 
    Se envía de Holanda a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Añadir al carrito

    Hardcover. 1st Edition. Two volumes. Royal octavo. Pp. xii, 196. Plus some folding charts. With corrections and annotations in very neat contemporary hand to some leaves. HARDCOVER, bound in contemporary cloth and marbled boards, shelf ticket to spine, old institutional stamp to title. In good condition. [AND:] Atlas. Quarto, comprising of title-page and 24 double-page lithographic plates with numerous illustrations to each. HARDCOVER, bound in the original publisher's cloth and printed boards, old stamp and shelf ticket, cover trifle soiled. In a very good condition, fine interior. ~ FIRST EDITION. Rare complete set which includes the Atlas. This comprises of numerous fine and very detailed technical illustrations of guns and cannons and their parts, accompanied by nomenclatures and extended explanations and measurements. Meticulously executed and lithographed in its entirety. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (ilustrador).…

  • Más imágenes

    Condición: Usado

    EUR 99,00

    Envío por EUR 35,00 
    Se envía de Holanda a Estados Unidos de America

    Cantidad disponible: 1 disponible

    Añadir al carrito

    Hardcover. 1st Edition. Two volumes. I. Text: Royal octavo. Pp. viii, 215. Tables. HARDCOVER, bound in the original publisher's cloth and printed boards, old small shelf tickets to spine, old institutional stamps to cover, prelims and title, some underlining, corrections and shoulder annotations. In good condition. II. Atlas: Quarto. Pp. Title-page, (i), and 16 double-page lithographic plates with numerous illustrations to each. HARDCOVER, bound in the original publisher's cloth and printed boards, old military institutional stamp on cover and two contemporary, rather decorative private stamps to title-page. In a very good condition. ~ FIRST EDITION. Very rare complete set. The Atlas comprises of numerous fine and very detailed technical illustrations of guns and cannons and their parts, accompanied by nomenclatures and extended explanations and measurements. Meticulously executed and lithographed in its entirety. One page in the text volume is heavily annotated in margins in contemporary hand, shading some light on the thought process of military cadets at the time. 009-01. ~ ~ NOTE: TOTAL REDUCTION SALE: THE PRICE OF THIS BOOK IS CURRENTLY REDUCED! ~ ~ (ilustrador).…

  • Idioma: Inglés

    Editorial: Springer, 2016

    1493948652 / 9781493948659

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa blanda
    • Impresión bajo demanda

    Librería: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 86,24

    Envío por EUR 30,00 
    Se envía de Italia a Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Condición: new. Questo è un articolo print on demand.

  • Idioma: Inglés

    Editorial: Springer, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura
    • Impresión bajo demanda

    Librería: Brook Bookstore On Demand, Napoli, NA, ItaliaBrook Bookstore On Demand

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 86,24

    Envío por EUR 34,00 
    Se envía de Italia a Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Condición: new. Questo è un articolo print on demand.

  • Idioma: Inglés

    Editorial: Springer New York Mrz 2015, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura
    • Impresión bajo demanda

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 106,99

    Envío por EUR 23,00 
    Se envía de Alemania a Estados Unidos de America

    Cantidad disponible: 2 disponibles

    Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology. 252 pp. Englisch. …

  • Idioma: Inglés

    Editorial: Springer New York Okt 2016, 2016

    1493948652 / 9781493948659

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa blanda
    • Impresión bajo demanda

    Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 106,99

    Envío por EUR 23,00 
    Se envía de Alemania a Estados Unidos de America

    Cantidad disponible: 2 disponibles

    Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book centers on gene therapy and gene transfer approaches to prevent or treat chronic virus infections. The main focus is on the Big Three: human immunodeficiency virus (HIV-1), hepatitis B virus (HBV) and hepatitis C virus (HCV). Ample anti-HIV drugs are currently available in the clinic and the development of an effective combination therapy has dramatically improved the lifespan and quality of life of infected individuals. A similar trend can already be recognized for HBV and HCV: the development of multiple (directly acting) antiviral drugs and plans to control or even cure the infection. However, approaches that help prevent infection, or which provide long-lasting treatment (such as a cure) remain important goals. Immunization through gene transfer vehicles encoding immunogenic viral proteins shows promise in preventing infections with complex, highly variable, viruses such as HIV-1 or HCV. Gene therapy applications for virus infections have been discussed since the early 1990's. Whereas a true cure seems difficult to achieve for HIV-1 due to its intrinsic property to deposit its genome into that of the host, such attempts may be within reach for HCV where spontaneous viral clearance occurs in a small percentage of the infected individuals. The prospect of original gene therapy approaches may provide alternative ways to reach the same endpoint by, for example, silencing of CCR5 expression post-transcriptionally. Many alternative antiviral strategies have been developed based on a variety of novel molecular methods: e.g. ribozymes. Some studies have progressed towards pre-clinical animal models and a few antiviral gene therapies have progressed towards clinical trials. This book provides an overview of this rapidly progressing field, while focusing on the interface of gene therapy and immunology/vaccinology. 252 pp. Englisch.…

  • Idioma: Inglés

    Editorial: Springer New York, 2016

    1493948652 / 9781493948659

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa blanda
    • Impresión bajo demanda

    Librería: moluna, Greven, Alemaniamoluna

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 92,27

    Envío por EUR 48,99 
    Se envía de Alemania a Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This book focuses on gene therapy and gene transfer approaches to prevent or treat chronoic virus infections Discusses a collection of molecular antiviral strategies (ribozymes, RNAi, RNAu, aptamers, etcCo-published with the American Societ. …

  • Idioma: Inglés

    Editorial: Springer New York, 2015

    1493924311 / 9781493924318

    Serie: Libro 65 de 490 - Advances in Experimental Medicine and Biology

    • Tapa dura
    • Impresión bajo demanda

    Librería: moluna, Greven, Alemaniamoluna

    Vendedor de 5 estrellas
    Contactar con el vendedor

    Condición: Nuevo

    EUR 92,27

    Envío por EUR 48,99 
    Se envía de Alemania a Estados Unidos de America

    Cantidad disponible: Más de 20 disponibles

    Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. This book focuses on gene therapy and gene transfer approaches to prevent or treat chronoic virus infections Discusses a collection of molecular antiviral strategies (ribozymes, RNAi, RNAu, aptamers, etcCo-published with the American Societ. …