Robert f goldstein (48 resultados)
Más imágenesThe Chinese: Adapting the Past, Building the Future
Robert F. Dernberger, Kenneth J. DeWoskin, Steven M. Goldstein, Rhoads Murphey, Martin K. Whyte
Idioma: Inglés
Editorial: Center for Chinese Studies, The University of Michigan, Ann Arbor, 1986
- Tapa blanda
Librería: Aspen Book Co., Denver, CO, Estados Unidos de AmericaAspen Book Co.
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Aceptable
EUR 8,86
Gastos de envío gratisSe envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Trade Paperback. Condición: Good. Estado de la sobrecubierta: no jacket (trade paperback). This trade paperback is in good condition, with minor wear on the cover edges. The spine is intact, and the pages are clean with no inscriptions or library markings. There is no dust jacket, as expected for this format. Overall, it is a well-preserved copy suitable for study or collection.…
Más imágenesIdioma: Inglés
Editorial: Dell Magazines, New York, 2007
- Tapa blanda
- Primera edición
- Revista/Periódico
Librería: Scene of the Crime, ABAC, IOBA, St. Catharines, ON, CanadaScene of the Crime, ABAC, IOBA
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Excelente
EUR 13,85
Gastos de envío gratisSe envía de Canada a Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoSoft cover. Condición: Fine. 1st Edition. First edition, first printing of this double issue of 18 pieces of writing including a serial, novelettes, short stories and poetry. Featured are Galaxy Blues (part one of four) Down and Out on Coyote by Allen M Steele (serial), Dark Integers by Greg Egan (novelette), Night Calls by Robert Reed (novelette), Nightfall by Isaac Asimov (novelette), Dark Rooms by Lisa Goldstein (novelette), At Sixes and Sevens by Carol Emshwiller (short story), Paid in Full by Susan Forest (short story), Leonid Skies by Carl Frederick (short story), Debatable Lands by Liz Williams (short stories), Skull Valley by Michael Cassutt (short story), The Turn by Chris Butler (short story), Modern Constellations by Pat Tompkins (poetry), Star People by Bruce Boston (poetry), Little Red Robot by GO Clark (poetry), Into the Deep by Michael Meyerhofer (poetry), Endangered by PMF Johnson (poetry), The Angel who Writes by Ruth Berman (poetry) and Staying the Course by Mark Rich (poetry). In Fine Condition.…

Idioma: Inglés
Editorial: Shambhala, 2020
- Tapa blanda
Librería: GreatBookPrices, Columbia, MD, Estados Unidos de AmericaGreatBookPrices
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 13,64
Envío por EUR 2,37Se envía dentro de Estados Unidos de AmericaCantidad disponible: Más de 20 disponibles
Condición: New.

Idioma: Inglés
Editorial: Shambhala, 2020
- Tapa blanda
Librería: GreatBookPrices, Columbia, MD, Estados Unidos de AmericaGreatBookPrices
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Como Nuevo
EUR 14,45
Envío por EUR 2,37Se envía dentro de Estados Unidos de AmericaCantidad disponible: Más de 20 disponibles
Condición: As New. Unread book in perfect condition.

FANTASTIC UNIVERSE: January, Jan. 1959
Fantastic Universe (Daniel F. Galouye; L. Sprague de Camp & Fletcher Pratt; Robert Moore Williams; Ivan T. Sanderson; Harry Harrison; Edmund Cooper; Harlan Ellison; Bertam Chandler; Hans Stefan Santesson; Evelyn Goldstein; Norbert F. Gariety)
Editorial: King-Size Publications, NY, 1959
- Tapa blanda
- Revista/Periódico
Librería: Books from the Crypt, N. Potomac, MD, Estados Unidos de AmericaBooks from the Crypt
Contactar con el vendedorVendedor de 5 estrellasMiembro de asociación: IOBA
Condición: Usado
EUR 5,54
Envío por EUR 4,93Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoWraps. Condición: Good+ to Very Good-. Vol. 11, No. 1. Edited by Hans Stefan Santesson. Cover art by Virgil Finlay. Includes "Trade Mission" by Daniel F. Galouye; "Ward of the Argonaut" by L. Sprague de Camp & Fletcher Pratt; "The Diamond Images" by Robert Moore Williams; "Now Meet the Nonterrestrial" by Ivan T. Sanderson; "The Robots Strike" by Harry Harrison; "The Enlightened Ones" by Edmund Cooper; "In Lonely Lands" by Harlan Ellison; "Time to Change" by Bertam Chandler; "Universe in Books" by Hans Stefan Santesson; "Man's Castle" by Evelyn Goldstein; "Too Hot to Handle" by Norbert F. Gariety. Spine competely faded; slight rubbing; tanning; edge and corner wear. Magazine.…
Editorial: Gulf Coast Association of Geological Societies., 1970
Librería: Eryops Books, Stephenville, TX, Estados Unidos de AmericaEryops Books
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Bueno
EUR 1,80
Envío por EUR 5,38Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoNo Binding. Condición: Very Good. ORIGINAL Articles, disbound from GCAGS Transactions volume; no covers; light foxing spots near fore-edge of a couple of pages, o/w in very good condition. Journal.

Tenacity in Children : Nurturing the Seven Instincts for Lifetime Success
Goldstein, Sam; Brooks, Robert B.; Crenshaw, David, Ph.D. (FRW)
- Tapa blanda
Librería: GreatBookPrices, Columbia, MD, Estados Unidos de AmericaGreatBookPrices
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 18,73
Envío por EUR 2,37Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Condición: New.
Editorial: Gulf Coast Association of Geological Societies., 1969
Librería: Eryops Books, Stephenville, TX, Estados Unidos de AmericaEryops Books
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Bueno
EUR 2,08
Envío por EUR 5,38Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoNo Binding. Condición: Very Good. ORIGINAL Article, disbound from GCAGS Transactions volume; no covers; in very good condition. Journal.

Tenacity in Children : Nurturing the Seven Instincts for Lifetime Success
Goldstein, Sam; Brooks, Robert B.; Crenshaw, David, Ph.D. (FRW)
- Tapa blanda
Librería: GreatBookPrices, Columbia, MD, Estados Unidos de AmericaGreatBookPrices
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Como Nuevo
EUR 20,98
Envío por EUR 2,37Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Condición: As New. Unread book in perfect condition.

FANTASTIC UNIVERSE: June 1957
Fantastic Universe (Harry Harrison; Marcia Kamien; Robert F. Young; Morton Klass; Harlan Ellison; Roger Dee; Robert Bloch; Evelyn Goldstein; Edward D. Hoch; Henry D. Billings; Stephen Bond; Mark Reinsberg)
Editorial: King-Size Publications, NY, 1957
- Revista/Periódico
Librería: Books from the Crypt, N. Potomac, MD, Estados Unidos de AmericaBooks from the Crypt
Contactar con el vendedorVendedor de 5 estrellasMiembro de asociación: IOBA
Condición: Usado - Aceptable
EUR 4,62
Envío por EUR 4,93Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoSingleIssueMagazine. Condición: Good. Vol. 7, No. 6. Edited by Hans Stefan Santesson. Cover art by Virgil Finlay. Includes "World in the Balance" by Harry Harrison; "Holiday" by Marcia Kamien; "Ape's Eye View" by Robert F. Young; "Day of Reckoning" by Morton Klass; "Commuter's Problem" by Harlan Ellison; "First landing" by Roger Dee; "Terror Over Hollywood" by Robert Bloch; "God of the Mist" by Evelyn Goldstein; "Versus" by Edward D. Hoch; "Snakes Alive" by Henry D. Billings; "Rock and Roll on Pluto" by Stephen Bond; "My Martian Cousin" by Mark Reinsberg. Spine scars, tears and losses and also to upper front and rear spine corner; tanning; does't sit flat. Book.…

Idioma: Inglés
Editorial: Center for Chinese Studies/University of Michigan, Ann Arbor MI 1991., 1991
- Tapa blanda
- Primera edición
Librería: Hay Cinema Bookshop Limited, Hay on Wye, Reino UnidoHay Cinema Bookshop Limited
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado
EUR 10,20
Envío por EUR 24,00Se envía de Reino Unido a Estados Unidos de AmericaCantidad disponible: 1 disponible
1st edition. 8vo. xvii + 802pp. Diagrams. Paperback in original pictorial red wrapps. with white lettering to faded spine, rubbed to edges. ISBN 0892641002 US$11.

Idioma: Inglés
Editorial: Shambhala, 2020
- Tapa blanda
Librería: GreatBookPricesUK, Woodford Green, Reino UnidoGreatBookPricesUK
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 17,20
Envío por EUR 18,00Se envía de Reino Unido a Estados Unidos de AmericaCantidad disponible: Más de 20 disponibles
Condición: New.

Idioma: Inglés
Editorial: Shambhala, 2020
- Tapa blanda
Librería: GreatBookPricesUK, Woodford Green, Reino UnidoGreatBookPricesUK
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Como Nuevo
EUR 20,46
Envío por EUR 18,00Se envía de Reino Unido a Estados Unidos de AmericaCantidad disponible: Más de 20 disponibles
Condición: As New. Unread book in perfect condition.

Tenacity in Children : Nurturing the Seven Instincts for Lifetime Success
Goldstein, Sam; Brooks, Robert B.; Crenshaw, David, Ph.D. (FRW)
- Tapa blanda
Librería: GreatBookPricesUK, Woodford Green, Reino UnidoGreatBookPricesUK
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 25,39
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Condición: New.

Rhode Island Jewish Historical Notes, Volume 11, Number 2 (November 1992)
Cohen, Judith Weiss (ed.); Carothers, Robert L.; Rotenberg, Joshua; Kusinitz, Bernard; Horvitz, Eleanor F.; Foster, Geraldine S.; Goldstein, Michael; Zurier, Melvin; Goldowsky, Seebert J.; Hurwitz, Stanley M.
Editorial: Rhode Island Jewish Historical Association, Providence, R.I., 1992
- Tapa blanda
Librería: Cat's Cradle Books, Archdale, NC, Estados Unidos de AmericaCat's Cradle Books
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado
EUR 29,54
Gastos de envío gratisSe envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoSoftcover. Condición: Very Good with no dust jacket. Sound binding. Clean, bright pages. Wrappers have light handling wear. Contents: Carothers, Marking another anniversary: the diaspora of the Sephardic Jews. Rotenberg, Black-Jewish relations in eighteenth cenury Newport. Kusinitz, The contribution of Newport's colonial Jews to the American way of life. Horvitz and Foster, Summers along lower Narragansett Bay: Narragansett pier and nearby areas. Goldstein, Alone, a Jew is nothing - Jewish community in Providence in the middle to late nineteenth century. Editor emeritus Goldowsky honored by Brown University School of Medicine. Zurier, Sons of Zion Synaogue - memories. Golowsky, 100th anniversary of Tempel Beth-El library. Hurwitz, Amerian Jewish Historical Society turns 100. Men of vision exhibit. Goldowsky, Bibliographical notes. Thirty-eighth annual meeting of the association. Necrology. Errata and addenda. Funds and bequests. Life members of the association. 9.0" tall; 158 pages.…

Tenacity in Children : Nurturing the Seven Instincts for Lifetime Success
Goldstein, Sam; Brooks, Robert B.; Crenshaw, David, Ph.D. (FRW)
- Tapa blanda
Librería: GreatBookPricesUK, Woodford Green, Reino UnidoGreatBookPricesUK
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Como Nuevo
EUR 27,12
Envío por EUR 18,00Se envía de Reino Unido a Estados Unidos de AmericaCantidad disponible: 1 disponible
Condición: As New. Unread book in perfect condition.

FANTASTIC UNIVERSE: January, Jan. 1955
Fantastic Universe (Milton Lesser; Walter M. Miller, Jr.; Evelyn Goldstein; Robert F. Young; Algis Budrys; Jeanne Williams; Russ Winterbotham; Horatio Winslow; F. B. Bryning; Bern Sharfman; Judith Merril; Joe Archibald; Frank Belknap Long)
Editorial: King-Size Publications, 1955
- Tapa blanda
Librería: HALCYON BOOKS, LONDON, Reino UnidoHALCYON BOOKS
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Bueno
EUR 12,98
Envío por EUR 21,60Se envía de Reino Unido a Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoSoftcover. Condición: Very Good. King-Size Publications 1955. Softcover with tight binding. Condition: Very Good. Clean and bright text. NEW EU 3 EURO CHARGE FOR IMPORTS IS INCLUDED IN OUR SHIPPING PRICE. ALL ITEMS ARE DISPATCHED FROM THE UK, ALL OVERSEAS ORDERS SENT BY TRACKABLE AIR MAIL. IF YOU ARE LOCATED OUTSIDE THE UK PLEASE ASK US FOR A POSTAGE QUOTE FOR MULTI VOLUME SETS BEFORE ORDERING.…

Anesthesiologist's Guide to the Or: Prepped
Dutton, Richard P., M.D.; Goldstein, Adam D.; Gantt, Robert M.; Lennon, Paul F.; Pudimat, Paul A.
- Tapa blanda
- Primera edición
Librería: BooksRun, Philadelphia, PA, Estados Unidos de AmericaBooksRun
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Regular
EUR 82,76
Gastos de envío gratisSe envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Paperback. Condición: Fair. First Edition. The item might be beaten up but readable. May contain markings or highlighting, as well as stains, bent corners, or any other major defect, but the text is not obscured in any way.

Anesthesiologist's Guide to the Or: Prepped
Dutton, Richard P., M.D.; Goldstein, Adam D.; Gantt, Robert M.; Lennon, Paul F.; Pudimat, Paul A.
- Tapa blanda
Librería: -OnTimeBooks-, Phoenix, AZ, Estados Unidos de America-OnTimeBooks-
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Bueno
EUR 84,72
Gastos de envío gratisSe envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Condición: very_good. Gently read. May have name of previous ownership, or ex-library edition. Binding tight; spine straight and smooth, with no creasing; covers clean and crisp. Minimal signs of handling or shelving. 100% GUARANTEE! Shipped with delivery confirmation, if you're not satisfied with purchase please return item! Ships USPS Media Mail.…
Más imágenesEditorial: Pulphouse Publishing, Eugene, 1991
- Tapa dura
- Primera edición
- Firmado
Librería: biblioboy, North Providence, RI, Estados Unidos de Americabiblioboy
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Excelente
EUR 46,15
Envío por EUR 6,27Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoHardcover. Condición: Fine. First Edition. Eugene Or.: Pulphouse Publishing 1991 Signed limited First Edition Copy #47/250 numbered copies signed by the contributors. Special Issue with stories by Charles de Lint, Dennis Etchison, John Brunner, Michael Bishop, Robert Sheckley, Esther M. Friesner, Nina Kirki Hoffman, Ken Wisman, William F. Wu, Lisa Goldstein, Jon Gustafson, Kara Dalkey. Brown leather binding with gold gilt lettering/decoration, page edges speckled, 247+ pages. Fine copy in Fine slipcase. See Photos clphE. …
Más imágenesEditorial: Pulphouse Publishing, Eugene, 1991
- Tapa dura
- Primera edición
- Firmado
Librería: biblioboy, North Providence, RI, Estados Unidos de Americabiblioboy
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Excelente
EUR 46,15
Envío por EUR 6,27Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Añadir al carritoHardcover. Condición: Fine. First Edition. Eugene Or.: Pulphouse Publishing 1991 Signed limited First Edition Copy #71 of 250 numbered copies signed by the contributors. Special Issue with stories by Charles de Lint, Dennis Etchison, John Brunner, Michael Bishop, Robert Sheckley, Esther M. Friesner, Nina Kirki Hoffman, Ken Wisman, William F. Wu, Lisa Goldstein, Jon Gustafson, Kara Dalkey. Brown leather binding with gold gilt lettering/decoration, page edges speckled, 247+ pages. Fine copy in Fine slipcase. See Photos clphE. …

Idioma: Inglés
Editorial: Kluwer, USA, 1994
- Tapa dura
Librería: The Book Exchange, Macclesfield, CHESH, Reino UnidoThe Book Exchange
Contactar con el vendedorVendedor de 4 estrellasCondición: Usado - Bueno
EUR 66,31
Envío por EUR 24,00Se envía de Reino Unido a Estados Unidos de AmericaCantidad disponible: 1 disponible
Hardcover. Condición: Very Good. 0792328361. Pharmaceutical company library hardcover, with minimal wear. 294 pages, index, illustrated with charts, tables and diagrams. Drug development has resulted in successful responses in childhood leukemia, testicular cancer and Hodgkin's disease. However, there are still many cancer-related deaths. Drug resistance is largely responsible for these failures and continues to be an area of active investigation. Drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, allowing us to explore the relationship between structure and function. In addition to clinical trials aimed at reversing MDR mediated drug resistance, gene therapy studies with MDR 1 gene retrovirally transduced into human bone marrow cells are described. MDR is the most understood mechanism of drug resistance, we are increasing our knowledge of alternative molecular and biochemical mechanisms of drug resistance to antimetabolites, cisplatin and alkylating agents and developing new strategies for circumventing such resistance. Many mechanisms exist by which cancer cells may overcome the cytotoxicity of our known chemotherapeutic agents. As understanding of these mechanisms expands, well designed models will be necessary to test laboratory hypotheses and determine their relationship to drug resistance in humans. It is this integration of basic science and clinical investigation that will both advance our scientific knowledge and result in the improvement of cancer therapy. Contents clean, tight and bright. Book. …

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases
Friedman, Herman; Honeyman, Allen; Lajtha, Able; Katz, Lynda J.; Bendinelli, Mauro; Weisman; Newland, Robert; Goldstein, Gerald; Beers, Sue R.; Howie, Alexander J.; Lance, Leonard L.; Lacy, Charles F.; Goldman, Morton P.; Young, David B.
- Tapa dura
Librería: Books Puddle, Woodside, NY, Estados Unidos de AmericaBooks Puddle
Contactar con el vendedorVendedor de 4 estrellasCondición: Nuevo
EUR 231,65
Envío por EUR 3,58Se envía dentro de Estados Unidos de AmericaCantidad disponible: 1 disponible
Condición: New. pp. 324.

Idioma: Inglés
Editorial: Springer, 2012
- Tapa blanda
Librería: California Books, Miami, FL, Estados Unidos de AmericaCalifornia Books
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 240,00
Envío por EUR 2,69Se envía dentro de Estados Unidos de AmericaCantidad disponible: Más de 20 disponibles
Condición: New.

Role of Proteases in the Pathophysiology of Neurodegenerative Diseases
Friedman, Herman; Honeyman, Allen; Lajtha, Able; Katz, Lynda J.; Bendinelli, Mauro; Weisman; Newland, Robert; Goldstein, Gerald; Beers, Sue R.; Howie, Alexander J.; Lance, Leonard L.; Lacy, Charles F.; Goldman, Morton P.; Young, David B.
- Tapa dura
Librería: Majestic Books, Hounslow, Reino UnidoMajestic Books
Contactar con el vendedorVendedor de 4 estrellasCondición: Nuevo
EUR 244,22
Envío por EUR 7,80Se envía de Reino Unido a Estados Unidos de AmericaCantidad disponible: 1 disponible
Condición: New. pp. 324 Illus.
Más imágenesIdioma: Inglés
Editorial: Humana, 2012
- Tapa blanda
Librería: preigu, Osnabrück, Alemaniapreigu
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 184,95
Envío por EUR 70,00Se envía de Alemania a Estados Unidos de AmericaCantidad disponible: 5 disponibles
Taschenbuch. Condición: Neu. Anticancer Drug Resistance | Advances in Molecular and Clinical Research | Lori J. Goldstein (u. a.) | Taschenbuch | xiii | Englisch | 2012 | Humana | EAN 9781461361299 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Idioma: Inglés
Editorial: Springer, 2012
- Tapa blanda
Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 241,76
Envío por EUR 35,00Se envía de Alemania a Estados Unidos de AmericaCantidad disponible: 1 disponible
Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomenon of drug resistance is largely responsible for these failures and continues to be an area of active investigation. Since the last volume in this series, we have learned that the energy-dependent drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, thus allowing us to explore the relationship between structure and function. In addition to ongoing well designed clinical trials aimed at reversing MDR mediated drug resistance, the first gene therapy studies with the MDR 1 gene retrovirally transduced into human bone marrow cells are about to be initiated. Although MDR is currently the most understood mechanism of drug resistance, we are uncovering increasing knowledge of alternative molecular and biochemical mechanisms of drug resistance to antimetabolites, cisplatin and alkylating agents and developing new strategies for circumventing such resistance. It is clear that drug resistance is complex, and many mechanisms exist by which cancer cells may overcome the cytotoxicity of our known chemotherapeutic agents. As our understanding of each of these mechanisms expands, well designed models will be necessary to test laboratory hypotheses and determine their relationship to drug resistance in humans. It is this integration of basic science and clinical investigation that will both advance our scientific knowledge and result in the improvement of cancer therapy. …

Idioma: Inglés
Editorial: Springer US, 1994
- Tapa dura
Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH
Contactar con el vendedorVendedor de 5 estrellasCondición: Nuevo
EUR 241,76
Envío por EUR 35,00Se envía de Alemania a Estados Unidos de AmericaCantidad disponible: 1 disponible
Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomenon of drug resistance is largely responsible for these failures and continues to be an area of active investigation. Since the last volume in this series, we have learned that the energy-dependent drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, thus allowing us to explore the relationship between structure and function. In addition to ongoing well designed clinical trials aimed at reversing MDR mediated drug resistance, the first gene therapy studies with the MDR 1 gene retrovirally transduced into human bone marrow cells are about to be initiated. Although MDR is currently the most understood mechanism of drug resistance, we are uncovering increasing knowledge of alternative molecular and biochemical mechanisms of drug resistance to antimetabolites, cisplatin and alkylating agents and developing new strategies for circumventing such resistance. It is clear that drug resistance is complex, and many mechanisms exist by which cancer cells may overcome the cytotoxicity of our known chemotherapeutic agents. As our understanding of each of these mechanisms expands, well designed models will be necessary to test laboratory hypotheses and determine their relationship to drug resistance in humans. It is this integration of basic science and clinical investigation that will both advance our scientific knowledge and result in the improvement of cancer therapy.…

Idioma: Inglés
Editorial: Springer, 1994
- Tapa dura
Librería: Bookmonger.Ltd, HILLSIDE, NJ, Estados Unidos de AmericaBookmonger.Ltd
Contactar con el vendedorVendedor de 5 estrellasCondición: Usado - Bueno
EUR 287,07
Envío por EUR 3,58Se envía dentro de Estados Unidos de AmericaCantidad disponible: 2 disponibles
Hardcover. Condición: Very Good.

Idioma: Inglés
Editorial: Springer, 2012
- Tapa blanda
Librería: Books Puddle, Woodside, NY, Estados Unidos de AmericaBooks Puddle
Contactar con el vendedorVendedor de 4 estrellasCondición: Nuevo
EUR 320,45
Envío por EUR 3,58Se envía dentro de Estados Unidos de AmericaCantidad disponible: 4 disponibles
Condición: New. pp. 312.