Ozols j (37 resultados)

PF. Condición: New.

Hardcover. Condición: Very Good. ***Please Read*** Latvian edition - Book shows slight wear with no DJ - interior is tight and clean - 528 pages - my shelf location - 32-a-53*.

HC. Condición: Gut. Ohln, originalgetreuer Umschlag (Faks,), ., gr 8?,368s., in gutem Zustand, [GSA7,6a] Deu 700g.

Hardcover. Condición: Very Good. 0792328361. Pharmaceutical company library hardcover, with minimal wear. 294 pages, index, illustrated with charts, tables and diagrams. Drug development has resulted in successful responses in childhood leukemia, testicular cancer and Hodgkin's disease. However, there are still many cancer-related deaths. Drug resistance is largely responsible for these failures and continues to be an area of active investigation. Drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, allowing us to explore the relationship between structure and function. In addition to clinical trials aimed at reversing MDR mediated drug resistance, gene therapy studies with MDR 1 gene retrovirally transduced into human bone marrow cells are described. MDR is the most understood mechanism of drug resistance, we are increasing our knowledge of alternative molecular and biochemical mechanisms of drug resistance to antimetabolites, cisplatin and alkylating agents and developing new strategies for circumventing such resistance. Many mechanisms exist by which cancer cells may overcome the cytotoxicity of our known chemotherapeutic agents. As understanding of these mechanisms expands, well designed models will be necessary to test laboratory hypotheses and determine their relationship to drug resistance in humans. It is this integration of basic science and clinical investigation that will both advance our scientific knowledge and result in the improvement of cancer therapy. Contents clean, tight and bright. Book. …

PAP. Condición: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Condición: New.

Taschenbuch. Condición: Neu. Anticancer Drug Resistance | Advances in Molecular and Clinical Research | Lori J. Goldstein (u. a.) | Taschenbuch | xiii | Englisch | 2012 | Humana | EAN 9781461361299 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu. …

Condición: New. In English.

Condición: New. In English.

Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomenon of drug resistance is largely responsible for these failures and continues to be an area of active investigation. Since the last volume in this series, we have learned that the energy-dependent drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, thus allowing us to explore the relationship between structure and function. In addition to ongoing well designed clinical trials aimed at reversing MDR mediated drug resistance, the first gene therapy studies with the MDR 1 gene retrovirally transduced into human bone marrow cells are about to be initiated. Although MDR is currently the most understood mechanism of drug resistance, we are uncovering increasing knowledge of alternative molecular and biochemical mechanisms of drug resistance to antimetabolites, cisplatin and alkylating agents and developing new strategies for circumventing such resistance. It is clear that drug resistance is complex, and many mechanisms exist by which cancer cells may overcome the cytotoxicity of our known chemotherapeutic agents. As our understanding of each of these mechanisms expands, well designed models will be necessary to test laboratory hypotheses and determine their relationship to drug resistance in humans. It is this integration of basic science and clinical investigation that will both advance our scientific knowledge and result in the improvement of cancer therapy. …

Hardcover. Condición: Very Good.

Condición: New. pp. 312.

Paperback. Condición: Brand New. reprint edition. 308 pages. 9.25x6.10x0.74 inches. In Stock.

Condición: New. pp. 312.

Hardcover. Condición: Brand New. 10.00x6.75x0.75 inches. In Stock.

Paperback. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

PAP. Condición: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Riga. Zinatne. 192 pp., 104 figs, hardcover gr. 8 [17.5 x 22 cm] [in Latvian].

M. Portr. u. einigen Abb. 621 S. OLwd. et 0 gr.

Condición: Gut. Zustand: Gut | Seiten: 200 | Sprache: Deutsch | Produktart: Bücher | Keine Beschreibung verfügbar.

Paperback / softback. Condición: New. This item is printed on demand. New copy - Usually dispatched within 5-9 working days.

Condición: New. Print on Demand.

Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. KlappentextrnrnMeet Jim. He has some typical problems: his marriage is on the rocks and his relationship with his teenage kids is even worse. He s been betrayed professionally, and exploited by a gun-running uncle.nn nnAnd he s stranded 50,000 y.…

Taschenbuch. Condición: Neu. Clan of the Cave-Lion | I. J. Ozols | Taschenbuch | Kartoniert / Broschiert | Englisch | 2004 | AuthorHouse | EAN 9781418488697 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.

Condición: new. Questo è un articolo print on demand.

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin s disease. We are still, however, confronted with over 500,000 cancer-relate.…

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin s disease. We are still, however, confronted with over 500,000 cancer-relate.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomenon of drug resistance is largely responsible for these failures and continues to be an area of active investigation. Since the last volume in this series, we have learned that the energy-dependent drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, thus allowing us to explore the relationship between structure and function. In addition to ongoing well designed clinical trials aimed at reversing MDR mediated drug resistance, the first gene therapy studies with the MDR 1 gene retrovirally transduced into human bone marrow cells are about to be initiated. Although MDR is currently the most understood mechanism of drug resistance, we are uncovering increasing knowledge of alternative molecular and biochemical mechanisms of drug resistance to antimetabolites, cisplatin and alkylating agents and developing new strategies for circumventing such resistance. It is clear that drug resistance is complex, and many mechanisms exist by which cancer cells may overcome the cytotoxicity of our known chemotherapeutic agents. As our understanding of each of these mechanisms expands, well designed models will be necessary to test laboratory hypotheses and determine their relationship to drug resistance in humans. It is this integration of basic science and clinical investigation that will both advance our scientific knowledge and result in the improvement of cancer therapy. 312 pp. Englisch. …

Buch. Condición: Neu. Anticancer Drug Resistance | Advances in Molecular and Clinical Research | Robert F. Ozols (u. a.) | Buch | Einband - fest (Hardcover) | Englisch | 1994 | Springer US | EAN 9780792328360 | Verantwortliche Person für die EU: Springer Heidelberg, Tiergartenstr. 17, 69121 Heidelberg, buchhandel-buch[at]springer[dot]com | Anbieter: preigu Print on Demand.…

Buch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Over the last 50 years, drug development and clinical trials have resulted in successful complete responses in diseases such as childhood leukemia, testicular cancer and Hodgkin's disease. We are still, however, confronted with over 500,000 cancer-related deaths per year. Clearly, the phenomenon of drug resistance is largely responsible for these failures and continues to be an area of active investigation. Since the last volume in this series, we have learned that the energy-dependent drug efflux protein, p-glycoprotein, encoded by the MDR 1 gene, is a member of a family of structurally related transport polypeptides, thus allowing us to explore the relationship between structure and function. In addition to ongoing well designed clinical trials aimed at reversing MDR mediated drug resistance, the first gene therapy studies with the MDR 1 gene retrovirally transduced into human bone marrow cells are about to be initiated. Although MDR is currently the most understood mechanism of drug resistance, we are uncovering increasing knowledge of alternative molecular and biochemical mechanisms of drug resistance to antimetabolites, cisplatin and alkylating agents and developing new strategies for circumventing such resistance. It is clear that drug resistance is complex, and many mechanisms exist by which cancer cells may overcome the cytotoxicity of our known chemotherapeutic agents. As our understanding of each of these mechanisms expands, well designed models will be necessary to test laboratory hypotheses and determine their relationship to drug resistance in humans. It is this integration of basic science and clinical investigation that will both advance our scientific knowledge and result in the improvement of cancer therapy. …