Librería: Ammareal, Morangis, Francia
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Añadir al carritoHardcover. Condición: Bon. Ancien livre de bibliothèque avec équipements. Edition 2006. Ammareal reverse jusqu'à 15% du prix net de cet article à des organisations caritatives. ENGLISH DESCRIPTION Book Condition: Used, Good. Former library book. Edition 2006. Ammareal gives back up to 15% of this item's net price to charity organizations.
Librería: killarneybooks, Inagh, CLARE, Irlanda
EUR 22,40
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Añadir al carritoHardcover. Condición: Very Good. Hardcover, xxxiii + 543 pages, illustrated, NOT ex-library. A clean copy with unmarked text, free of inscriptions and stamps. Issued without a dust jacket. Contents: Alois Alzheimer [Concerning a unique disease of the cerebral cortex; History of Alzheimer's first case Auguste D; Alzheimer & beginnings of research into Alzheimer's disease; Alzheimer & the myth of the pioneer]; Beginning of modern research [Alzheimer's Disease at mid-Century; Alzheimer's disease research]; Anatomy & Neuropsychology [Anatomical changes underlying dementia in Alzheimer's disease; Staging of cortical neurofibrillary inclusions of the Alzheimer's type; Of stains & brains: how microscopic & clinical observations contributed to the understanding of Alzheimer's disease; Presenile forms of Alzheimer's disease in 2006]; Cholinergic Deficit [Acetylcholine in AD: Expectations meet reality]; Amyloid & Genetics [Discovery of [Beta] Amyloid; Pathways to the discovery of the neuronal origin & proteolytic biogenesis of A[Beta] amyloid of Alzheimer's disease; Amyloid Hypothesis: history & alternatives; Segregation of a missense mutation in the amyloid [Beta]-protein precursor gene with familial Alzheimer's disease; From the amyloid [Beta] protein (A4) to isolation of the first Alzheimer's disease gene: amyloid [Beta] (A4) precursor protein (APP); Commentary on "Correlative memory deficits, A[Beta] elevation & amyloid plaques in transgenic mice"; Vision for the future: pathogenesis, models & experimental therapeutics; PS1, PS2 & APP mutations that cause Alzheimer's disease increase A[Beta]42; Amyloid precursor protein, AD & Down's syndrome; Catabolism of amyloid [Beta] peptide & pathogenesis of sporadic Alzheimer's disease; Synaptic activity, amyloid-[Beta] & AD; Molecular pathogenesis of AD in human peripheral cells: platelets show it all; Neuronal origin hypothesis of cerebral amyloid angiopathy; Neuropathologist & Alzheimer genetics; Genetics, molecular biology & animal modeling of AD; Genetic Alzheimer-frontotemporal dementia spectrum; Mutation of the AD amyloid gene in hereditary cerebral hemorrhage, Dutch type; Physiological generation of Amyloid [Beta]-peptide & its Consequences for AD Research; Activation of [Alpha]-secretase as an approach for treatment of AD; Challenges to the enigma of [gamma]-secretase & to AD; Targeting [gamma]-Secretase; Presenilin/gamma-secretase complex & its potential as a drug target; Identification of [Beta]-secretase]; ApoE [Apolipoprotein E & AD; Apolipoprotein E4: From synaptic remodeling to genetic risk factor in both familial & sporadic AD]; Tau [Alzheimer tangle: 100 years on; Immunological demonstration of tau protein in nearofibrillary tangles; Bulk isolation of neurofibrillary tangles & discoveries of tau & its abnormal hyperphosphorylation; Natural & molecular history of AD; Tau focused drug discovery for AD & related Neurodegenerative Tauopathies; Ubiquitin is a component of paired helical filaments; Influence of tau on neuronal traffic mechanisms; Search for structure of tau & paired helical filaments]; Oxidative Stress [Changing landscape of AD: From Insoluble to Soluble & from Pathogen to Protector; Molecular & cellular pathways towards and away from AD]; Epidemiology [Paquid]; Imaging [Hippocampal imaging in the early diagnosis of AD 1988 to 2006; Detecting Early-Stage AD in MCI & PreMCI; Imaging the pathology of AD: Building on a century-Old blueprint]; Therapeutical Perspectives [How do we test drugs; Inflammation & lesions of AD; A[Beta] immunotherapy prevents & Reverses AD neuropathology; Immunotherapy; "Magic" bullets, shotguns or cocktails to treat or prevent AD?; Seventh age of man: Solving senility]; Forum & Network [Fondation Ipsen & AD: a 20-year relationship; Alzheimer Research Forum: A Knowledge Base and e-Community for AD Research; Potamkin prize for research in Pick's, Alzheimer's and related diseases]; Subject Index.
Idioma: Inglés
Publicado por Springer-Verlag, Berlin, 2006
ISBN 10: 3540376518 ISBN 13: 9783540376514
Librería: PsychoBabel & Skoob Books, Didcot, Reino Unido
EUR 65,59
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Añadir al carritoHardcover. Condición: Very Good. Hardcover (no jacket) in very good condition. One or two slight bumps and signs of wear to the board edges. A few light marks on the page block. Pages are clean; all text and colour images are clear. CM. Used.
Idioma: Inglés
Publicado por Springer Publishing Company, Berlin, 2006
ISBN 10: 3540376518 ISBN 13: 9783540376514
Librería: San Francisco Book Company, Paris, Francia
EUR 50,00
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Añadir al carritoHardcover. Condición: Very good. Hardcover Octavo no dust jacket. illustrated boards, white lettering, no dust jacket, 543 pp.
Librería: MaxiBooks, Paris, Francia
EUR 120,00
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Añadir al carritoRelié. Condición: D'occasion - Comme neuf. === ENVOIE LE JOUR MEME ===.
Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 163,13
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Añadir al carritoCondición: New. In.
Librería: Books Puddle, New York, NY, Estados Unidos de America
EUR 188,81
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Añadir al carritoCondición: New. pp. 156.
Librería: Books Puddle, New York, NY, Estados Unidos de America
EUR 208,51
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Añadir al carritoCondición: New. pp. 168.
EUR 140,00
Cantidad disponible: 5 disponibles
Añadir al carritoTaschenbuch. Condición: Neu. Proteopathic Seeds and Neurodegenerative Diseases | Yves Christen (u. a.) | Taschenbuch | xii | Englisch | 2015 | Springer-Verlag GmbH | EAN 9783642446962 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, 2015
ISBN 10: 3642446965 ISBN 13: 9783642446962
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 160,49
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Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer's disease, increasingly implicates the conversion of disease-specific proteins into an aggregate-prone b-sheet-rich state as the prime mover of the neurodegenerative process. This prion-like corruptive protein templating or seeding now characterizes such clinically and etiologically diverse neurological disorders as Alzheimer s disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration. Understanding the misfolding, aggregation, trafficking and pathogenicity of the affected proteins could therefore reveal universal pathomechanistic principles for some of the most devastating and intractable human brain disorders. It is time to accept that the prion concept is no longer confined to prionoses but is a promising concept for the understanding and treatment of a remarkable variety of diseases that afflict primarily our aging society.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2013
ISBN 10: 3642354904 ISBN 13: 9783642354908
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 160,49
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Añadir al carritoBuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans. The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain uncertain. A recent surge of research, first instigated by pathologic similarities between prion disease and Alzheimer's disease, increasingly implicates the conversion of disease-specific proteins into an aggregate-prone b-sheet-rich state as the prime mover of the neurodegenerative process. This prion-like corruptive protein templating or seeding now characterizes such clinically and etiologically diverse neurological disorders as Alzheimer s disease, Parkinson's disease, Huntington's disease, amyotrophic lateral sclerosis, and frontotemporal lobar degeneration. Understanding the misfolding, aggregation, trafficking and pathogenicity of the affected proteins could therefore reveal universal pathomechanistic principles for some of the most devastating and intractable human brain disorders. It is time to accept that the prion concept is no longer confined to prionoses but is a promising concept for the understanding and treatment of a remarkable variety of diseases that afflict primarily our aging society.
EUR 234,13
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Añadir al carritoHardcover. Condición: Brand New. 2013 edition. 175 pages. 9.25x6.25x0.50 inches. In Stock.
EUR 231,46
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Añadir al carritoPaperback. Condición: Brand New. 2013 edition. 168 pages. 9.25x6.10x0.38 inches. In Stock.
Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 247,96
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Añadir al carritoCondición: New. In.
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Añadir al carritoCondición: New.
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Añadir al carritoCondición: New.
EUR 277,91
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Añadir al carritoCondición: As New. Unread book in perfect condition.
Librería: Mispah books, Redhill, SURRE, Reino Unido
EUR 258,80
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Añadir al carritoHardcover. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.
EUR 277,38
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Añadir al carritoCondición: As New. Unread book in perfect condition.
Librería: Ria Christie Collections, Uxbridge, Reino Unido
EUR 308,54
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Añadir al carritoCondición: New. In.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, 2006
ISBN 10: 3540376518 ISBN 13: 9783540376514
Librería: moluna, Greven, Alemania
EUR 267,86
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Añadir al carritoGebunden. Condición: New.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, 2010
ISBN 10: 3642072321 ISBN 13: 9783642072321
Librería: moluna, Greven, Alemania
EUR 267,86
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Añadir al carritoCondición: New.
EUR 332,22
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Añadir al carritoCondición: New. pp. 580.
Librería: California Books, Miami, FL, Estados Unidos de America
EUR 344,30
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Añadir al carritoCondición: New.
EUR 345,08
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Añadir al carritoCondición: New. pp. 580.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, 2010
ISBN 10: 3642072321 ISBN 13: 9783642072321
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 320,99
Cantidad disponible: 1 disponibles
Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event, 'Alzheimer 100 Years and Beyond' organized on the initiation of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, was the highlight of the Year of Alzheimer. However, beyond these few months of tributes, the centennial offers a unique opportunity to assess both the progress achieved and the uncertainties remaining. This volume, a collection comprised mainly of articles by the invited speakers and also of a few other prominent researchers, is meant to be a record of those events.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2006
ISBN 10: 3540376518 ISBN 13: 9783540376514
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 320,99
Cantidad disponible: 1 disponibles
Añadir al carritoBuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Few medical or scientific addresses have so unmistakeably made history as the presentation delivered by Alois Alzheimer on November 4, 1906 in Tübingen. The celebratory event, 'Alzheimer 100 Years and Beyond' organized on the initiation of the Alzheimer community in Germany and worldwide, in collaboration with the Fondation Ipsen, was the highlight of the Year of Alzheimer. However, beyond these few months of tributes, the centennial offers a unique opportunity to assess both the progress achieved and the uncertainties remaining. This volume, a collection comprised mainly of articles by the invited speakers and also of a few other prominent researchers, is meant to be a record of those events.
Librería: Mispah books, Redhill, SURRE, Reino Unido
EUR 397,14
Cantidad disponible: 1 disponibles
Añadir al carritoHardcover. Condición: Like New. Like New. book.
EUR 454,51
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Añadir al carritoHardcover. Condición: Brand New. 1st edition. 543 pages. 9.25x6.25x0.75 inches. In Stock.
Librería: Brook Bookstore On Demand, Napoli, NA, Italia
EUR 126,26
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Añadir al carritoCondición: new. Questo è un articolo print on demand.