Frank van der kooy (7 resultados)

Softcover. Condición: Fine. First Edition. stapled format, 60 pages. light shelf wear and usage markings. excellent binding. [SK]. Our orders are shipped using tracked courier delivery services.

Condición: New. pp. 132.

Paperback. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: van der Kooy FrankFrank van der Kooy was born in 1975 in Pretoria, South Africa. Henstudied at the University of Pretoria and completed his PhD atnthe Department of Plant Sciences. His research focussed on thendevelopment of naphthoq.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The antimycobacterial activity of severalnaphthoquinones initiated this study into theoccurrence, chemistry and biological activity ofthese compounds. This book deals with the traditionaluse of plants to treat TB-like symptoms and attemptsto establish a link between naphthoquinones and theseplants with the use of a metabolomics approach. Itfurthermore deals with the chemical synthesis of themain lead compound and some derivatives. This isfollowed by the often neglected stability studiesperformed on the main active compounds. These studiesshowed that rapid breakdown of lead compounds dooccur during activity and toxicity testing, and thatthis leads to false positives and negatives. Theactivity and toxicity of the main active compoundswere tested using three models: Vero cells, mice andMusca domestica. The last chapters deal with theinvestigation of a structure activity relationshipand propose a mechanism of action for thesenaphthoquinones. It was found that this class ofcompounds interfere with the electron transport chainby inhibiting menaquinone to bind to the cytochromecomplex. This indicates that these compounds mightbecome a new class of antibiotics.…

Condición: New. Print on Demand pp. 132 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Condición: New. PRINT ON DEMAND pp. 132.