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Condición: New. This is a Brand-new US Edition. This Item may be shipped from US or any other country as we have multiple locations worldwide.

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Kein Einband. Condición: Sehr gut. Hardcover, leichte Gebrauchsspuren, Springer 2004, Versand weltweit / international shipping.

Condición: New. pp. viii + 123 1st Edition.

Condición: New. pp. viii + 123 Illus.

Condición: New. pp. viii + 123.

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Condición: New. pp. viii + 120.

Condición: New. pp. viii + 120 28 Illus.

Hardcover. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Condición: New. pp. viii + 120.

Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Information is provided from the basic and clinical sciences on the mechanisms damaging the brain from trauma or ischemia. New aspects involve the endoplasmic reticulum, mitochondrial failure, pathobiology of axonal injury, molecular signals activating glial elements, or the emerging therapeutical role of neurotrophins. Experimental issues involve a better analysis of the ischemic penumbra, the salvagable tissue. Therapeutic contributions reach from the environmental influence to gene expression, including neuroprotection, such as hibernation mother nature s experiment or hypothermia which is reported to induce cell swelling. Treatment issues deal also with thrombolysis and combination therapies, or with the clearance of adverse blood components LDL/fibrinogen by a novel procedure using heparin. Other highlights are discussing the specificities of pediatric vs. adult brain trauma, or the evolving role of the Apolipoprotein-E e4 gene in severe head injury. An update is also provided on an online assessment of the patient management during the pre- and early hospital phase in Southern Bavaria. The empirical observation of neuroworsening is analyzed in further details, whether this is a specificity autonomously driving the posttraumatic course. Finally, the unsolved question why drug trials in severe head injury have failed so far in view of the promising evidence from the laboratory is subjected to an expert analysis.

Condición: New.

Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The international interdisciplinary gathering of top of secondary brain damage in brain trauma, as ac level clinical and laboratory scientists in Mauls, Italy knowledged from the beginning of these workshops in has developed from its beginning in 1984into a fruitful Mauls, the significance of inflammation is all but clear. tradition where worldwide experts active and knowl Although inflammatory phenomena are seen in trauma edgeable in cerebral ischemia and trauma convene for and ischemia ofthe brain, as activation ofwhite blood update and exchanges of their most recent clinical and cells with emigration into the tissue presumably en experimental findings and concepts. These meetings hancing damage, inflammatory cells may have benefi have, of course, experienced shifts in emphasis from cial properties as well. Thechapter on the Janus-faceof the past until now, corresponding to the most actual inflammation isanalyzing this ambiguity. developments, which were fascinating clinicians and The exploration of novel cell-biological mechanisms laboratory scientists alike. The current Supplement of on a molecular or more systemic basis causing apop Acta Neurochirurgica is an example in case. Its virtue totic cell death, inflammation, or regeneration, provide as before is that authors contribute articles in a review useful objectives for therapeutical interventions ex like manner on their own field of research, according pected to be more specific than the present treatment to the platform presentations at the meeting as indis modalities.

Paperback. Condición: Brand New. reprint edition. 132 pages. 11.00x8.20x0.40 inches. In Stock.

Paperback. Condición: Brand New. reprint edition. 140 pages. 11.00x8.20x0.33 inches. In Stock.

Condición: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Information is provided from the basic and clinical sciences on the mechanisms damaging the brain from trauma or ischemia. New aspects involve the endoplasmic reticulum, mitochondrial failure, pathobiology of axonal injury, molecular signals activating glial elements, or the emerging therapeutical role of neurotrophins. Experimental issues involve a better analysis of the ischemic penumbra, the salvagable tissue. Therapeutic contributions reach from the environmental influence to gene expression, including neuroprotection, such as hibernation ¿ mother nature¿s experiment ¿ or hypothermia which is reported to induce cell swelling. Treatment issues deal also with thrombolysis and combination therapies, or with the clearance of adverse blood components ¿ LDL/fibrinogen ¿ by a novel procedure using heparin. Other highlights are discussing the specificities of pediatric vs. adult brain trauma, or the evolving role of the Apolipoprotein-E e4 gene in severe head injury. An update is also provided on an online assessment of the patient management during the pre- and early hospital phase in Southern Bavaria. The empirical observation of neuroworsening is analyzed in further details, whether this is a specificity autonomously driving the posttraumatic course. Finally, the unsolved question why drug trials in severe head injury have failed so far in view of the promising evidence from the laboratory is subjected to an expert analysis.

Hardcover. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

weicher Einband. 294 S., einige Abb Lit.verz. Abb. 4° Br. *Stempel auf Titel, sehr gutes Expl.*. Sprache: Deutsch.

fester Einband. 246 S. Lit.verz. Reg. Abb. Kart. *sehr gutes Expl.*. Sprache: Deutsch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Information is provided from the basic and clinical sciences on the mechanisms damaging the brain from trauma or ischemia. New aspects involve the endoplasmic reticulum, mitochondrial failure, pathobiology of axonal injury, molecular signals activating glial elements, or the emerging therapeutical role of neurotrophins. Experimental issues involve a better analysis of the ischemic penumbra, the salvagable tissue. Therapeutic contributions reach from the environmental influence to gene expression, including neuroprotection, such as hibernation mother nature s experiment or hypothermia which is reported to induce cell swelling. Treatment issues deal also with thrombolysis and combination therapies, or with the clearance of adverse blood components LDL/fibrinogen by a novel procedure using heparin. Other highlights are discussing the specificities of pediatric vs. adult brain trauma, or the evolving role of the Apolipoprotein-E e4 gene in severe head injury. An update is also provided on an online assessment of the patient management during the pre- and early hospital phase in Southern Bavaria. The empirical observation of neuroworsening is analyzed in further details, whether this is a specificity autonomously driving the posttraumatic course. Finally, the unsolved question why drug trials in severe head injury have failed so far in view of the promising evidence from the laboratory is subjected to an expert analysis. 132 pp. Englisch.

Condición: new. Questo è un articolo print on demand.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The international interdisciplinary gathering of top of secondary brain damage in brain trauma, as ac level clinical and laboratory scientists in Mauls, Italy knowledged from the beginning of these workshops in has developed from its beginning in 1984into a fruitful Mauls, the significance of inflammation is all but clear. tradition where worldwide experts active and knowl Although inflammatory phenomena are seen in trauma edgeable in cerebral ischemia and trauma convene for and ischemia ofthe brain, as activation ofwhite blood update and exchanges of their most recent clinical and cells with emigration into the tissue presumably en experimental findings and concepts. These meetings hancing damage, inflammatory cells may have benefi have, of course, experienced shifts in emphasis from cial properties as well. Thechapter on the Janus-faceof the past until now, corresponding to the most actual inflammation isanalyzing this ambiguity. developments, which were fascinating clinicians and The exploration of novel cell-biological mechanisms laboratory scientists alike. The current Supplement of on a molecular or more systemic basis causing apop Acta Neurochirurgica is an example in case. Its virtue totic cell death, inflammation, or regeneration, provide as before is that authors contribute articles in a review useful objectives for therapeutical interventions ex like manner on their own field of research, according pected to be more specific than the present treatment to the platform presentations at the meeting as indis modalities. 144 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Molecular and Cellular Mechanisms.- Disturbance of Endoplasmic Reticulum Functions: A Key Mechanism Underlying Cell Damage .- Role and Mechanisms of Secondary Mitochondrial Failure.- Initiating Mechanisms Involved in the Pathobiology of Traumatically Induced Axonal Injury and Interventions Targeted at Blunting Their Progression.- Molecular Signals for Glial Activation: Pro- and Anti-Inflammatory Cytokines in the Injured Brain.- Mechanical and Excitotoxic Lesion of Motoneurons: Effects of Neurotrophins and Ciliary Neurotrophic Factor on Survival and Regeneration.- News from Cerebral Ischemia.- Modelling of the Ischemic Penumbra.- The Acute Ischemic Penumbra: Topography, Life Span, and Therapeutic Response.- Environmental Influence on Gene Expression and Recovery from Cerebral Ischemia.- Neuroprotective Strategies in Nature - Novel Clues for the Treatment of Stroke and Trauma.- Glial Cell Swelling - Effect of Hypothermia.- The Clot Thickens - Thrombolysis and Combination Therapies.- Assessment of Brain Tissue Viability Under Clinical Circumstances.- Heparin-Mediated Extracorporeal LDL/Fibrinogen Precipitation - H.E.L.P. - In Coronary and Cerebral Ischemia.- Remaining Problems in Severe Head Injury.- Pediatric Head Injury: What is Unique and Different.- Apolipoprotein E and the Response of the Brain to Injury.- System Analysis of Patient Management During the Pre- and Early Clinical Phase in Severe Head Injury.- The Frequency, Antecedent Events, and Causal Relationships of Neurologic Worsening Following Severe Head Injury.- Neuroprotective Effects of Riluzole in Neurotrauma Models: A Review.- Challenges in Translating the Efficacy of Neuroprotective Agents in Experimental Models Into Knowledge of Clinical Benefits in Head Injured Patients.- Author Index.- Indexof Keywords.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 132 pp. Englisch.