Idioma: Inglés
Publicado por Berlin ; Heidelberg ; New York ; London ; Paris ; Tokyo ; Hong Kong ; Barcelona ; Budapest : Springer, 1995
ISBN 10: 3540588566 ISBN 13: 9783540588566
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Añadir al carritogebundene Ausgabe. Condición: Gut. 614 S. Das hier angebotene Buch stammt aus einer teilaufgelösten wissenschaftlichen Bibliothek und trägt die entsprechenden Kennzeichnungen (Rückenschild, Instituts-Stempel.); leichte altersbedingte Anbräunung des Papiers; der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. ENGLISCH. Sprache: Englisch Gewicht in Gramm: 950.
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Añadir al carritoTaschenbuch. Condición: Neu. Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds | Emel Arinç (u. a.) | Taschenbuch | 508 S. | Englisch | 2012 | Springer | EAN 9781468472868 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - This volume represents the proceedings of a NATO Advanced Study Institute on 'Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds' which was held in ~eme (Izmir) Turkey, August 27 to September 7, 1989. The Institute emphasized the potential dangers of drugs, pollutants, pesticides, carcinogens, and both nutrient and non-nutrient food additives and their interactions at the molecular level. These xenobiotics are metabolized in phase I reactions by monooxygenases, primarly cytochrome P450-isozyme dependent, followed by phase II conjugation enzymes. The versatility of these enzymes is unique in biochemistry since they catalyze the metabolism of an almost limitless number of compounds through a diverse array of reactions. Although these metabolic sequences are usually detoxication mechanisms, in some cases the reactive intermediates are more mutagenic, more carcinogenic and ultimately more toxic than the parent compound. The Institute was devoted to recent scientific progress in the understanding of the biochemical and molecular properties of these enzymes and factors that influence the metabolism of chemicals to toxic and non-toxic compounds. Overview lectures focused on xenobiotic metabolism by cytochrome P450, the flavin-containing monooxygenase, cytochrome b5, epoxide hydrolase, glutathione S-transferase and UDP-glucuronosyl transferase. Several additional presentations stressed various aspects of cytochrome P450 mediated metabolism including: specific forms in the rabbit and insects; topology in membranes; posttranslational modification; control of constitutive forms in the rat; hormonal and xenobiotic regulation; prostanoid metabolism; endogenous substrate metabolism; interaction with estrogenic pesticides; pesticide bioactivation. The Institute also included talks on interactions between enzymes and on benzene metabolism and toxicity.
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Añadir al carritoCondición: Good. Your purchase helps support Sri Lankan Children's Charity 'The Rainbow Centre'. Ex-library, so some stamps and wear, but in good overall condition. Our donations to The Rainbow Centre have helped provide an education and a safe haven to hundreds of children who live in appalling conditions.
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Añadir al carritoCondición: New. pp. 636.
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Añadir al carritoTaschenbuch. Condición: Neu. Molecular Aspects of Oxidative Drug Metabolizing Enzymes | Their Significance in Environmental Toxicology, Chemical Carcinogenesis and Health | Emel Arinc (u. a.) | Taschenbuch | Einband - flex.(Paperback) | Englisch | 2011 | Springer-Verlag GmbH | EAN 9783642795305 | Verantwortliche Person für die EU: Lauinger, Sonia, Sonia Lauinger, Lauinger Verlag, Heinrich-Köhler-Platz 8, 76187 Karlsruhe, mail[at]lauinger-verlag[dot]de | Anbieter: preigu.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, 2011
ISBN 10: 3642795307 ISBN 13: 9783642795305
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Añadir al carritoPaperback. Condición: Brand New. 623 pages. 9.00x6.10x1.40 inches. In Stock.
Idioma: Inglés
Publicado por Springer Berlin Heidelberg, Springer Berlin Heidelberg, 2011
ISBN 10: 3642795307 ISBN 13: 9783642795305
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Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Presented here are recent advances in biochemical, toxicological, and regulatory aspects of oxidative drug metabolizing enzymes. Mainly cytochrome P450-dependent and flavin-containing monooxygenases (FMO) are covered. Moreover, the book deals with genotoxicity studies and toxicological interactions of environmental chemicals and mechanisms of mutagenicity and tumor formation. The construction of genetically engineered mammalian cells for the production of a specific P450 isozyme and the application of these cell lines in drug metabolism, mutagenicity and toxicity studies are described in detail. Further, insight is provided into how a number of aquatic species cope with pollutants and their genotoxicity.
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Añadir al carritoCondición: New. pp. 308.
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Añadir al carritoTaschenbuch. Condición: Neu. Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes | Emel Arinç (u. a.) | Taschenbuch | viii | Englisch | 2012 | Springer | EAN 9781461372028 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Añadir al carritoTaschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The NATO Advanced Study Institute of 'Molecular and Applied Aspects of Oxida tive Drug Metabolizing Enzymes' was held in Tekirova, Antalya, Turkey, from August 31 to September 11, 1997. This Institute was the third of a series of the NATO ASIs on a similar topic relating to the enzymes of oxidative metabolism of xenobiotics. The first NATO ASI in this series, entitled 'Molecular Aspects of Monooxygenases and Bioactiva tion of Toxic Compounds' (NATO ASI Series A: Life Sciences, Vol. 202), was held in.
Idioma: Inglés
Publicado por Springer US, Springer US, 1999
ISBN 10: 0306460483 ISBN 13: 9780306460487
Librería: AHA-BUCH GmbH, Einbeck, Alemania
EUR 168,73
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Añadir al carritoBuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The NATO Advanced Study Institute of 'Molecular and Applied Aspects of Oxida tive Drug Metabolizing Enzymes' was held in Tekirova, Antalya, Turkey, from August 31 to September 11, 1997. This Institute was the third of a series of the NATO ASIs on a similar topic relating to the enzymes of oxidative metabolism of xenobiotics. The first NATO ASI in this series, entitled 'Molecular Aspects of Monooxygenases and Bioactiva tion of Toxic Compounds' (NATO ASI Series A: Life Sciences, Vol. 202), was held in.
Librería: Revaluation Books, Exeter, Reino Unido
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Añadir al carritoPaperback. Condición: Brand New. reprint edition. 302 pages. 10.00x7.00x0.73 inches. In Stock.
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Añadir al carritoHardcover. Condición: Brand New. 1st edition. 294 pages. 10.00x6.75x0.75 inches. In Stock.
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Idioma: Inglés
Publicado por Springer, Springer Dez 2012, 2012
ISBN 10: 1468472860 ISBN 13: 9781468472868
Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, Alemania
EUR 53,49
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Añadir al carritoTaschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume represents the proceedings of a NATO Advanced Study Institute on 'Molecular Aspects of Monooxygenases and Bioactivation of Toxic Compounds' which was held in ~eme (Izmir) Turkey, August 27 to September 7, 1989. The Institute emphasized the potential dangers of drugs, pollutants, pesticides, carcinogens, and both nutrient and non-nutrient food additives and their interactions at the molecular level. These xenobiotics are metabolized in phase I reactions by monooxygenases, primarly cytochrome P450-isozyme dependent, followed by phase II conjugation enzymes. The versatility of these enzymes is unique in biochemistry since they catalyze the metabolism of an almost limitless number of compounds through a diverse array of reactions. Although these metabolic sequences are usually detoxication mechanisms, in some cases the reactive intermediates are more mutagenic, more carcinogenic and ultimately more toxic than the parent compound. The Institute was devoted to recent scientific progress in the understanding of the biochemical and molecular properties of these enzymes and factors that influence the metabolism of chemicals to toxic and non-toxic compounds. Overview lectures focused on xenobiotic metabolism by cytochrome P450, the flavin-containing monooxygenase, cytochrome b5, epoxide hydrolase, glutathione S-transferase and UDP-glucuronosyl transferase. Several additional presentations stressed various aspects of cytochrome P450 mediated metabolism including: specific forms in the rabbit and insects; topology in membranes; posttranslational modification; control of constitutive forms in the rat; hormonal and xenobiotic regulation; prostanoid metabolism; endogenous substrate metabolism; interaction with estrogenic pesticides; pesticide bioactivation. The Institute also included talks on interactions between enzymes and on benzene metabolism and toxicity. 512 pp. Englisch.
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Añadir al carritoCondición: New. Print on Demand pp. 512 66:B&W 7 x 10 in or 254 x 178 mm Perfect Bound on White w/Gloss Lam.
Librería: Biblios, Frankfurt am main, HESSE, Alemania
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Añadir al carritoCondición: New. PRINT ON DEMAND pp. 512.