Epigenomics (369 resultados)

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X, 245 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Methods in Molecular Biology; 1112. Sprache: Englisch. …

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Hardcover. Condición: New. Contents: 1. Introduction 2. DNA Methylation Analysis 3. Histone Modification Analysis 4. RNA Modification Analysis 5. Epigenetic Analysis 6. Epigenetic Profiling and Epigenetic Landscape 7. Epigenomics 8. Epigenomes 9. Epigenome Editing 10. RNA Editing and its Programmability 11. Epitranscriptomics 12. Applications of Epigenomics Glossary Index. Epigenomics deals in detail with the concepts, principles, procedures, developments, limitations, advantages, applications and future prospects of different areas of epigenomics in a comprehensive manner. It provides concise yet complete knowledge on the many aspects of the basic and most recent methods and applications in epigenomics, a branch of epigenetics that deals with the mechanisms such as DNA modifications, histone modifications, RNA modifications, small and long non-coding RNAs, chromatin remodelling, which are involved in epigenetic control of gene expression without involving variations in DNA sequences. These regulatory mechanisms lead to phenotypic variations. These epigenetic mechanisms can be exploited for crop improvement and cure of human diseases. Epigenomics strives to understand the role of epigenetic marks (chemical tags) in the development of phenotype. This understanding provides epigeneticists to apply epigenomics in medicine and agriculture. Self-explanatory adequately labelled figures have been the special emphasis throughout.…

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Hardcover. Condición: New. No Jacket. 1st Edition. Academic Press (2016). New Hardcover. No dj. 9.25"x6.25"x0.8". be46960.

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Condición: Very Good. Very Good++; Hardcover; Unmarked covers with "straight" edge-corners; Unblemished textblock edges; The endpapers and all text pages are bright and unmarked; Binding is tight with a straight spine; This book will be stored and delivered in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); Green and blue covers with title in white lettering; 2013, Springer-Verlag Publishing; 339 pages; "Environmental Epigenomics in Health and Disease: Epigenetics and Complex Diseases (Epigenetics and Human Health)," by Randy L. Jirtle & Frederick L. Tyson.…

Hardcover. Condición: Fine. 3642368263 Fine/As New; Hardcover; This book is brand new and still sealed in the publisher's original shrinkwrap; Perfect, new condition; This book will be stored and delivered in a sturdy cardboard box with foam padding; Medium Format (8.5" - 9.75" tall); Blue and green covers with title in white lettering; 2013, Springer-Verlag Publishing; 339 pages; "Environmental Epigenomics in Health and Disease: Epigenetics and Complex Diseases (Epigenetics and Human Health)," by Randy L. Jirtle & Frederick L. Tyson.…

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Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The term epigenetics describes regulatory and information storing mechanisms of specific genes that do not involve any change of their DNA sequence. Epigenetics is closely related to the extensively folded state, in which the genome is packaged, known as chromatin. New genomic tools nowadays allow the genome-wide assessment of, for example, chromatin states and DNA modifications, and led to the discovery of unexpected new epigenetic principles, such as epigenomic memory. This was the start of the field of epigenomics, the relation of which to human health and disease is discussed in this textbook. This book aims to summarize, in a condensed form, the role of epigenomics in defining chromatin states that are representative of active genes (euchromatin) and repressed genes (heterochromatin). Moreover, this book discusses the principles of gene regulation, chromatin stability, genomic imprinting and the reversibility of DNA methylation and histone modifications. This information should enable a better understanding of cell type identities and will provide new directions for studies of, for example, cellular reprograming, the response of chromatin to environmental signals and epigenetic therapies that can improve or restore human health. In order to facilitate the latter, we favor a high figure-to-text ratio following the rule 'a picture tells more than thousand words'. The content of the book is based on the lecture course 'Molecular Medicine and Genetics' that is given by one of us (C. Carlberg) in different forms since 2002 at the University of Eastern Finland in Kuopio. Thematically, this book is located between our textbooks 'Mechanisms of Gene Regulation' (ISBN 978-94-017-7741-4) and 'Nutrigenomics' (ISBN 978-3-319-30415-1), studying of which may also be interesting to our readers. The book is sub-divided into three sections and 13chapters. Following the Introduction (sectionA), sectionB will explain the molecularbasis of epigenomics, while sectionC will provide examples for the impact of epigenomics in human health and disease. The lecture course is primarily designed for Master level students of biomedicine, but is also frequented by PhD students as well as by students of other bioscience disciplines. Besides its value as a textbook,Human Epigenomicswill be a useful reference for individuals working in biomedicine.…

Paperback. Condición: new. Paperback. This volume details state-of-the-art computational methods designed to manage, analyze, and generally leverage epigenomic and epitranscriptomic data. Chapters guide readers through fine-mapping and quantification of modifications, visual analytics, imputation methods, supervised analysis, and integrative approaches for single-cell data. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Computational Epigenomics and Epitranscriptomics aims to provide an overview of epiomic protocols, making it easier for researchers to extract impactful biological insight from their data. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.…

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