Combinatorial library methods protocols (29 resultados)

Hardcover. Condición: Very Good. 0896039803. Hardcover, from closed pharmaceutical company library. Minor bump on one corner. Lending record shows this book has been borrowed three times only. 383 pages, index, illustrated with charts, tables and diagrams. A novel series of computational and laboratory methods for the design, synthesis, quality control, screening, and purification of just such combinatorial libraries. Here the reader will find cutting-edge techniques for the preparation of encoded combinatorial libraries, for the synthesis of DNA-binding polyamides, and for combinatorial receptors. There are also state-of-the-art methods for computational library design, quality control by mass spectrometry, and structure verification using 1D and 2D NMR.Sections include: Contents as new, clean, tight and bright. Book.…

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hardcover. Condición: Good. Ex- library copy with stamps and stickers.

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Hardcover. Condición: New. In shrink wrap. Looks like an interesting title.

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Hardcover. Condición: Brand New. 313 pages. 9.50x6.50x1.00 inches. In Stock.

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Condición: New. Presents a series of computational and laboratory methods for the design, synthesis, quality control, screening, and purification of just such combinatorial libraries. This book provides techniques for the preparation of encoded combinatorial libraries, for the synthesis of DNA-binding polyamides, and for combinatorial receptors. Editor(s): English, Lisa B. Series: Methods in Molecular Biology. Num Pages: 383 pages, biography. BIC Classification: GLC; MQP. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 25. Weight in Grams: 1670. . 2002. Hardback. . . . .…

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Paperback. Condición: Brand New. reprint edition. 394 pages. 9.01x5.98x0.91 inches. In Stock.

Condición: New. Presents a series of computational and laboratory methods for the design, synthesis, quality control, screening, and purification of just such combinatorial libraries. This book provides techniques for the preparation of encoded combinatorial libraries, for the synthesis of DNA-binding polyamides, and for combinatorial receptors. Editor(s): English, Lisa B. Series: Methods in Molecular Biology. Num Pages: 383 pages, biography. BIC Classification: GLC; MQP. Category: (P) Professional & Vocational; (UP) Postgraduate, Research & Scholarly; (UU) Undergraduate. Dimension: 254 x 178 x 25. Weight in Grams: 1670. . 2002. Hardback. . . . . Books ship from the US and Ireland.…

Hardcover. Condición: New. ISBN:9780896039803.

Paperback. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

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Condición: New. Brand New! Fast Delivery This is an International Edition and ship within 24-48 hours. Deliver by FedEx and Dhl, & Aramex, UPS, & USPS and we do accept APO and PO BOX Addresses. Order can be delivered worldwide within 6-10 days and we do have flat rate for up to 2LB. Extra shipping charges will be requested if the Book weight is more than 5 LB. This Item May be shipped from India, United states & United Kingdom. Depending on your location and availability.…

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Buch. Condición: Neu. Combinatorial Library | Methods and Protocols | Lisa B. English | Buch | xi | Englisch | 2002 | Humana | EAN 9780896039803 | Verantwortliche Person für die EU: Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu Print on Demand. …

Buch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The continued successes of large- and small-scale genome sequencing projects are increasing the number of genomic targets available for drug d- covery at an exponential rate. In addition, a better understanding of molecular mechanisms-such as apoptosis, signal transduction, telomere control of ch- mosomes, cytoskeletal development, modulation of stress-related proteins, and cell surface display of antigens by the major histocompatibility complex m- ecules-has improved the probability of identifying the most promising genomic targets to counteract disease. As a result, developing and optimizing lead candidates for these targets and rapidly moving them into clinical trials is now a critical juncture in pharmaceutical research. Recent advances in com- natorial library synthesis, purification, and analysis techniques are not only increasing the numbers of compounds that can be tested against each specific genomic target, but are also speeding and improving the overall processes of lead discovery and optimization. There are two main approaches to combinatorial library production: p- allel chemical synthesis and split-and-mix chemical synthesis. These approaches can utilize solid- or solution-based synthetic methods, alone or in combination, although the majority of combinatorial library synthesis is still done on solid support. In a parallel synthesis, all the products are assembled separately in their own reaction vessels or microtiter plates. The array of rows and columns enables researchers to organize the building blocks to be c- bined, and provides an easy way to identify compounds in a particular well.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The continued successes of large- and small-scale genome sequencing projects are increasing the number of genomic targets available for drug d- covery at an exponential rate. In addition, a better understanding of molecular mechanisms-such as apoptosis, signal transduction, telomere control of ch- mosomes, cytoskeletal development, modulation of stress-related proteins, and cell surface display of antigens by the major histocompatibility complex m- ecules-has improved the probability of identifying the most promising genomic targets to counteract disease. As a result, developing and optimizing lead candidates for these targets and rapidly moving them into clinical trials is now a critical juncture in pharmaceutical research. Recent advances in com- natorial library synthesis, purification, and analysis techniques are not only increasing the numbers of compounds that can be tested against each specific genomic target, but are also speeding and improving the overall processes of lead discovery and optimization. There are two main approaches to combinatorial library production: p- allel chemical synthesis and split-and-mix chemical synthesis. These approaches can utilize solid- or solution-based synthetic methods, alone or in combination, although the majority of combinatorial library synthesis is still done on solid support. In a parallel synthesis, all the products are assembled separately in their own reaction vessels or microtiter plates. The array of rows and columns enables researchers to organize the building blocks to be c- bined, and provides an easy way to identify compounds in a particular well.…