Apoptosis immune system (20 resultados)

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Taschenbuch. Condición: Neu. The Role of HIV Genetic Pathway in Apoptosis | HIV physiological role in cell death and survival of cells in the human immune system | Shahin Asadi | Taschenbuch | 164 S. | Englisch | 2016 | LAP LAMBERT Academic Publishing | EAN 9783659931048 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Taschenbuch. Condición: Neu. Aspects of Poriferan Apoptosis and Immune System | Aspects of Poriferan (Suberites domuncula) Apoptosis and Innate Immune System and Evolutionary Implications | Bérengère Luthringer | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639214932 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Condición: Gut. Zustand: Gut | Seiten: 432 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Condición: Sehr gut. Zustand: Sehr gut | Seiten: 432 | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Taschenbuch. Condición: Neu. Apoptosis induced by cytotoxic cells of the immune system | The role of heat shock protein 70 and sulphatases 1 and 2 in granzyme B-induced apoptosis | Sara Yasemin Demiroglu | Taschenbuch | 192 S. | Englisch | 2015 | Südwestdeutscher Verlag für Hochschulschriften | EAN 9783838111704 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

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Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - High Quality Content by WIKIPEDIA articles! Caspases, or cysteine-aspartic proteases, are a family of cysteine proteases, which play essential roles in apoptosis (programmed cell death), necrosis and inflammation. Caspases are essential in cells for apoptosis, or programmed cell death, in development and most other stages of adult life, and have been termed 'executioner' proteins for their roles in the cell. Some caspases are also required in the immune system for the maturation of cytokines. Failure of apoptosis is one of the main contributions to tumour development and autoimmune diseases; this coupled with the unwanted apoptosis that occurs with ischemia or Alzheimer's disease, has stimulated interest in caspases as potential therapeutic targets since they were discovered in the mid 1990s.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Please note that the content of this book primarily consists of articles available from Wikipedia or other free sources online. HHV Latency Associated Transcript (HHV LAT) is a length of RNA which accumulates in cells hosting long-term, or latent, Human Herpes Virus (HHV) infections. The LAT RNA is produced by genetic transcription from a certain region of the viral DNA. LAT regulates the viral genome and interferes with the normal activities of the infected host cell. Herpes virus may establish life-long infection during which a reservoir virus population survives in host nerve cells for long periods of time. Such long-term Herpes infection requires a mode of cellular infection known as latent infection. During the latent infection, the metabolism of the host cell is disrupted. While the infected cell would ordinarily undergo an organized death or be removed by the immune system, the consequences of LAT production interfere with these normal processes. Latency is distinguished from lytic infection; in lytic infection many Herpes virus particles are produced and then burst or lyse the host cell. Lytic infection is sometimes known as 'productive' infection.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Intracellular heat shock protein 70 (HSP70) belongs to the stress response system and can protect cells from different apoptotic stimuli. Extracellular HSP70 on the other hand can activate cells of the innate and adaptive immune system. Acute overexpression of intracellular HSP70 could even increase the susceptibility of melanoma cells to cytotoxic T-lymphocytes (CTLs) that use the granule-exocytosis pathway for killing (Dressel et al. 1999). To decipher the molecular pathway of this increased susceptibility to CTLs, the effect of the acute overexpression of HSP70 on gene expression was analysed in cells, in which Hsp70 is under the control of a tetracycline-inducible promoter. To reduce the complexity of CTL-induced apoptosis, further experiments were performed with granzyme (Gr)B, a component of the cytotoxic granules of CTLs and NK cells, that has been shown to interact with HSP70. Heparan sulphates on the other hand are involved in GrB-binding to target cells of CTLs and are modified in their sulphation pattern by sulphatases 1 and 2. The role of HSP70 and sulphatases 1 and 2 in GrB-induced apoptosis is analysed. 192 pp. Englisch.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Survivin, a unique member of the family of inhibitors of apoptosis (IAP) proteins, orchestrates intracellular pathways during cell division and apoptosis. Its central regulatory function has inspired several approaches that target survivin for cancer therapy. Analyses in early-branching Metazoa so far propose an exclusive role of survivin as a chromosomal passenger protein, whereas only later during evolution the second, complementary antiapoptotic function might have arisen, concurrent with increased organismal complexity. To lift the veil on the ancestral function(s) of this key regulatory molecule, a survivin homologue of the phylogenetically oldest extant metazoan taxon (phylum Porifera) was identified and functionally characterized. Additionally, new components of the innate defense sentinel in sponges were also identified. This new prototypes could represent a very efficient defense mechanism and may correspond to a new family of intracellular sensing protein, forming a subclass of pattern recognition receptors (PRR).…

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Intracellular heat shock protein 70 (HSP70) belongs to the stress response system and can protect cells from different apoptotic stimuli. Extracellular HSP70 on the other hand can activate cells of the innate and adaptive immune system. Acute overexpression.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Intracellular heat shock protein 70 (HSP70) belongs to the stress response system and can protect cells from different apoptotic stimuli. Extracellular HSP70 on the other hand can activate cells of the innate and adaptive immune system. Acute overexpression of intracellular HSP70 could even increase the susceptibility of melanoma cells to cytotoxic T-lymphocytes (CTLs) that use the granule-exocytosis pathway for killing (Dressel et al. 1999). To decipher the molecular pathway of this increased susceptibility to CTLs, the effect of the acute overexpression of HSP70 on gene expression was analysed in cells, in which Hsp70 is under the control of a tetracycline-inducible promoter. To reduce the complexity of CTL-induced apoptosis, further experiments were performed with granzyme (Gr)B, a component of the cytotoxic granules of CTLs and NK cells, that has been shown to interact with HSP70. Heparan sulphates on the other hand are involved in GrB-binding to target cells of CTLs and are modified in their sulphation pattern by sulphatases 1 and 2. The role of HSP70 and sulphatases 1 and 2 in GrB-induced apoptosis is analysed.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Today, HIV and AIDS is a global problem and epidemic disorders in the world. Every year the number of HIV infected individuals increases. Many studies have been done a cure for HIV, but the treatment is appropriate and decisive undiscovered. In this book, the physiological role of HIV in cell death was studied.Apoptosis of uninfected bystander cells is a key element of HIV pathogenesis and believed to be the driving force behind the selective depletion of CD4+ T cells leading to immunodeficiency. While several viral proteins have been implicated in this process the complex interaction between Env glycoprotein expressed on the surface of infected cells and the receptor and co-receptor expressing bystander cells has been proposed as a major mechanism. HIV-1 utilizes CD4 as the primary receptor for entry into cells; however, it is the viral co-receptor usage that greatly influences CD4 decline and progression to AIDS. This phenomenon is relatively simple for X4 viruses, which arise later during the course of the disease, are considered to be highly fusogenic, and cause a rapid CD4+ T cell decline. However, in contrast, R5 viruses in general have a greater transmissibility, are encount.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Intracellular heat shock protein 70 (HSP70) belongs to the stress response system and can protect cells from different apoptotic stimuli. Extracellular HSP70 on the other hand can activate cells of the innate and adaptive immune system. Acute overexpression of intracellular HSP70 could even increase the susceptibility of melanoma cells to cytotoxic T-lymphocytes (CTLs) that use the granule-exocytosis pathway for killing (Dressel et al. 1999). To decipher the molecular pathway of this increased susceptibility to CTLs, the effect of the acute overexpression of HSP70 on gene expression was analysed in cells, in which Hsp70 is under the control of a tetracycline-inducible promoter. To reduce the complexity of CTL-induced apoptosis, further experiments were performed with granzyme (Gr)B, a component of the cytotoxic granules of CTLs and NK cells, that has been shown to interact with HSP70. Heparan sulphates on the other hand are involved in GrB-binding to target cells of CTLs and are modified in their sulphation pattern by sulphatases 1 and 2. The role of HSP70 and sulphatases 1 and 2 in GrB-induced apoptosis is analysed.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 192 pp. Englisch.…

Taschenbuch. Condición: Neu. Caspase | Cysteine protease, Apoptosis, Necrosis, Inflammation, Cell (biology), Developmental biology, Immune system, Cytokines, Tumour, Ischemia | Frederic P. Miller (u. a.) | Taschenbuch | Englisch | 2026 | OmniScriptum | EAN 9786130856786 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand.…

Taschenbuch. Condición: Neu. HHV Latency Associated Transcript | Herpesviridae, Transcription (genetics), DNA, Immune system, Lytic cycle, Intron, Apoptosis, MiRNA, TGF beta, Thrombospondin | Frederic P. Miller (u. a.) | Taschenbuch | Englisch | 2026 | OmniScriptum | EAN 9786131603501 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu Print on Demand.…