Isbn: 9798190825497 - neuroscience of pain and anesthesia: molecular mechanisms, clinical pharmacology, perioperative analgesia, and translational therapies (5 resultados)

PAP. Condición: New. New Book. Shipped from UK. Established seller since 2000.

PAP. Condición: New. New Book. Shipped from UK. Established seller since 2000.

Taschenbuch. Condición: Neu. Neuware - A comprehensive clinical and scientific guide to pain neuroscience, anesthesia, analgesic pharmacology, and emerging therapiesNeuroscience of Pain and Anesthesia connects the molecular biology of nociception with the practical management of acute, chronic, perioperative, neuropathic, cancer-related, and complex pain conditions. Written for clinicians, trainees, researchers, and healthcare professionals, this first edition explains how pain signals are generated, transmitted, modified, perceived, and treated.The book begins with the neural anatomy of pain, including peripheral nociceptors, spinal processing, ascending pathways, cortical networks, and descending inhibitory systems. It then examines ion channels, neurotransmitters, inflammatory mediators, neuroimmune interactions, peripheral sensitization, central sensitization, glial activation, and the neuroplastic mechanisms that contribute to persistent pain.Clinical chapters provide detailed coverage of pain classification, bedside assessment, quantitative sensory testing, opioid and non-opioid analgesics, general anesthesia, regional anesthesia, local anesthetics, neuromuscular blockade, postoperative pain management, and enhanced recovery protocols.Major topics include: - Molecular and cellular mechanisms of nociception- Peripheral and central pain sensitization- Acute, chronic, neuropathic, inflammatory, and nociplastic pain- Opioid pharmacology, tolerance, dependence, and hyperalgesia- NSAIDs, acetaminophen, antidepressants, anticonvulsants, and topical therapies- General anesthetics and mechanisms of unconsciousness- Spinal, epidural, and ultrasound-guided regional anesthesia- Local anesthetic systemic toxicity and emergency management- Neuromuscular blocking drugs and reversal agents- Multimodal perioperative analgesia and patient-controlled analgesia- Neuropathic pain, cancer pain, and palliative analgesia- Pediatric, obstetric, geriatric, and cognitively impaired patients- Visceral pain, musculoskeletal pain, low back pain, and fibromyalgia- Spinal cord stimulation, radiofrequency ablation, and intrathecal therapy- Psychological approaches to chronic pain- Opioid addiction, harm reduction, and responsible prescribing- Gene therapy, monoclonal antibodies, artificial intelligence, and precision medicine- Ethical, legal, regulatory, and global perspectives on pain treatmentThe text integrates basic neuroscience, clinical pharmacology, anesthetic practice, interventional pain medicine, psychology, ethics, and translational research. It is suitable for anesthesiologists, pain physicians, neurologists, surgeons, pharmacists, nurses, residents, fellows, medical students, and researchers seeking a structured reference on modern pain and anesthesia science.A practical resource for understanding pain mechanisms, selecting appropriate therapies, improving perioperative analgesia, and evaluating the future of pain medicine. …

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Paperback. Condición: new. Paperback. A comprehensive clinical and scientific guide to pain neuroscience, anesthesia, analgesic pharmacology, and emerging therapiesNeuroscience of Pain and Anesthesia connects the molecular biology of nociception with the practical management of acute, chronic, perioperative, neuropathic, cancer-related, and complex pain conditions. Written for clinicians, trainees, researchers, and healthcare professionals, this first edition explains how pain signals are generated, transmitted, modified, perceived, and treated.The book begins with the neural anatomy of pain, including peripheral nociceptors, spinal processing, ascending pathways, cortical networks, and descending inhibitory systems. It then examines ion channels, neurotransmitters, inflammatory mediators, neuroimmune interactions, peripheral sensitization, central sensitization, glial activation, and the neuroplastic mechanisms that contribute to persistent pain.Clinical chapters provide detailed coverage of pain classification, bedside assessment, quantitative sensory testing, opioid and non-opioid analgesics, general anesthesia, regional anesthesia, local anesthetics, neuromuscular blockade, postoperative pain management, and enhanced recovery protocols.Major topics include: Molecular and cellular mechanisms of nociceptionPeripheral and central pain sensitizationAcute, chronic, neuropathic, inflammatory, and nociplastic painOpioid pharmacology, tolerance, dependence, and hyperalgesiaNSAIDs, acetaminophen, antidepressants, anticonvulsants, and topical therapiesGeneral anesthetics and mechanisms of unconsciousnessSpinal, epidural, and ultrasound-guided regional anesthesiaLocal anesthetic systemic toxicity and emergency managementNeuromuscular blocking drugs and reversal agentsMultimodal perioperative analgesia and patient-controlled analgesiaNeuropathic pain, cancer pain, and palliative analgesiaPediatric, obstetric, geriatric, and cognitively impaired patientsVisceral pain, musculoskeletal pain, low back pain, and fibromyalgiaSpinal cord stimulation, radiofrequency ablation, and intrathecal therapyPsychological approaches to chronic painOpioid addiction, harm reduction, and responsible prescribingGene therapy, monoclonal antibodies, artificial intelligence, and precision medicineEthical, legal, regulatory, and global perspectives on pain treatmentThe text integrates basic neuroscience, clinical pharmacology, anesthetic practice, interventional pain medicine, psychology, ethics, and translational research. It is suitable for anesthesiologists, pain physicians, neurologists, surgeons, pharmacists, nurses, residents, fellows, medical students, and researchers seeking a structured reference on modern pain and anesthesia science.A practical resource for understanding pain mechanisms, selecting appropriate therapies, improving perioperative analgesia, and evaluating the future of pain medicine. This item is printed on demand. Shipping may be from our UK warehouse or from our Australian or US warehouses, depending on stock availability. …