9789400730403 - cell line development: 6 (cell engineering) (13 resultados)
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Taschenbuch. Condición: Neu. Cell Line Development | Mohamed Al-Rubeai | Taschenbuch | viii | Englisch | 2012 | Springer | EAN 9789400730403 | Verantwortliche Person für die EU: Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg, juergen[dot]hartmann[at]springer[dot]com | Anbieter: preigu.
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far grater in t…erms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms.This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity, improve cell function, glycosylation and secretion and control apoptosis. It presents an overall picture of the current topics central to expression engineering including such topics as epigenetics and the use of technologies to overcome positional dependent inactivation, the use of promoter and enhancer sequences for expression of various transgenes, site directed engineering of defined chromosomal sites, and examination of the role of eukaryotic nucleus as the controller of expression of genes that are introduced for production of a desired product. It includes a review of selection methods for high producers and an application developed by a major biopharmaceutical industry to expedite the cell line development process. The potential of cell engineering approch to enhance cell lines through the manipulation of single genes that play important roles in key metabolic and regulatory pathways is also explored throughout.
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Condición: new. Questo è un articolo print on demand.
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Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are… far grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms.This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity, improve cell function, glycosylation and secretion and control apoptosis. It presents an overall picture of the current topics central to expression engineering including such topics as epigenetics and the use of technologies to overcome positional dependent inactivation, the use of promoter and enhancer sequences for expression of various transgenes, site directed engineering of defined chromosomal sites, and examination of the role of eukaryotic nucleus as the controller of expression of genes that are introduced for production of a desired product. It includes a review of selection methods for high producers and an application developed by a major biopharmaceutical industry to expedite the cell line development process. The potential of cell engineering approch to enhance cell lines through the manipulation of single genes that play important roles in key metabolic and regulatory pathways is also explored throughout. 264 pp. Englisch.
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Editorial: Springer Netherlands, Springer Mär 2012 2012
Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Mammalian cell lines command an effective monopoly for the production of therapeutic proteins that require post-translational modifications. This unique advantage outweighs the costs associated with mammalian cell culture, which are far… grater in terms of development time and manufacturing when compared to microbial culture. The development of cell lines has undergone several advances over the years, essentially to meet the requirement to cut the time and costs associated with using such a complex hosts as production platforms. This book provides a comprehensive guide to the methodology involved in the development of cell lines and the cell engineering approach that can be employed to enhance productivity, improve cell function, glycosylation and secretion and control apoptosis. It presents an overall picture of the current topics central to expression engineering including such topics as epigenetics and the use of technologies to overcome positional dependent inactivation, the use of promoter and enhancer sequences for expression of various transgenes, site directed engineering of defined chromosomal sites, and examination of the role of eukaryotic nucleus as the controller of expression of genes that are introduced for production of a desired product. It includes a review of selection methods for high producers and an application developed by a major biopharmaceutical industry to expedite the cell line development process. The potential of cell engineering approch to enhance cell lines through the manipulation of single genes that play important roles in key metabolic and regulatory pathways is also explored throughout.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch.
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Editorial: Springer 2012
Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Librería: Majestic Books, Hounslow, , Reino UnidoMajestic Books
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Condición: New. Print on Demand pp. 264 49:B&W 6.14 x 9.21 in or 234 x 156 mm (Royal 8vo) Perfect Bound on White w/Gloss Lam.
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Editorial: Springer 2012
Serie: Cell Engineering, Libro 5 de 10. Libro 5 de 10 - Cell Engineering
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Librería: Biblios, frankfurt am main, HESSE, AlemaniaBiblios
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Condición: New. PRINT ON DEMAND pp. 264.
