9783838364087 - cd38 as a prognostic factor in b-cell chronic lymphocytic leukaemia: corelation with igvh gene mutational status de nabih, mostafa (8 resultados)

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Editorial: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG 2010
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Taschenbuch. Condición: Neu. CD38 AS A PROGNOSTIC FACTOR IN B-CELL CHRONIC LYMPHOCYTIC LEUKAEMIA | CORELATION WITH IgVH GENE MUTATIONAL STATUS | Mostafa Nabih | Taschenbuch | 168 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838364087 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42,… 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Chronic lymphocytic leukaemia follows an extremely variable clinical course with overall survival times ranging from months to decades, so there is a need to identify markers that may help to refine outcome prediction for these indi…viduals. One of the most important molecular genetics parameters defining pathogenic and prognostic subgroups of Chronic lymphocytic leukaemia is the mutation status of the IgVH genes. CD38 expression has demonstrated a highly predictive prognostic value and can be used as a convenient and accurate predictor of IgVH gene mutational status. However, because IgVH gene mutational status assay is characterized by its technical complexity, high cost and needs for high level of expertise while CD38 percent expression can be determined more conveniently, rapidly and cheaper than IgVH gene mutational status, it offer the possibility of a substitute for IgVH gene mutations analysis. Moreover it may be the preferred adjunct to the current staging systems. Indeed, the results of this simple test should enable physicians to predict with considerable accuracy whether a patient is likely to have a favorable or unfavorable clinical course. 168 pp. Englisch.

Idioma: Inglés
Editorial: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG 2010
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Condición: New. Print on Demand pp. 168 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Idioma: Inglés
Editorial: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG 2010
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Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Chronic lymphocytic leukaemia follows an extremely variable clinical course with overall survival times ranging from months to decades, so there is a need to identify markers that may help to refine outcome prediction for these individu…als. One of the most important molecular genetics parameters defining pathogenic and prognostic subgroups of Chronic lymphocytic leukaemia is the mutation status of the IgVH genes. CD38 expression has demonstrated a highly predictive prognostic value and can be used as a convenient and accurate predictor of IgVH gene mutational status. However, because IgVH gene mutational status assay is characterized by its technical complexity, high cost and needs for high level of expertise while CD38 percent expression can be determined more conveniently, rapidly and cheaper than IgVH gene mutational status, it offer the possibility of a substitute for IgVH gene mutations analysis. Moreover it may be the preferred adjunct to the current staging systems. Indeed, the results of this simple test should enable physicians to predict with considerable accuracy whether a patient is likely to have a favorable or unfavorable clinical course.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 168 pp. Englisch.

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Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Chronic lymphocytic leukaemia follows an extremely variable clinical course with overall survival times ranging from months to decades, so there is a need to identify markers that may help to refine outcome prediction for these individua…ls. One of the most important molecular genetics parameters defining pathogenic and prognostic subgroups of Chronic lymphocytic leukaemia is the mutation status of the IgVH genes. CD38 expression has demonstrated a highly predictive prognostic value and can be used as a convenient and accurate predictor of IgVH gene mutational status. However, because IgVH gene mutational status assay is characterized by its technical complexity, high cost and needs for high level of expertise while CD38 percent expression can be determined more conveniently, rapidly and cheaper than IgVH gene mutational status, it offer the possibility of a substitute for IgVH gene mutations analysis. Moreover it may be the preferred adjunct to the current staging systems. Indeed, the results of this simple test should enable physicians to predict with considerable accuracy whether a patient is likely to have a favorable or unfavorable clinical course.