ISBN: 9783838350912 - chlamydia pneumoniae lung infection in two inbred mouse strains: multivariate analysis of chlamydia pneumoniae lung infection in a/j and c57bl/6 mice (9 resultados)

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Taschenbuch. Condición: Neu. Chlamydia pneumoniae Lung Infection in Two Inbred Mouse Strains | Multivariate analysis of Chlamydia pneumoniae lung infection in A/J and C57BL/6 mice | Chengming Wang | Taschenbuch | 116 S. | Englisch | 2010 | LAP LAMBERT Academic Publishing | EAN 9783838350912 | Verantwortliche Person für die EU: BoD - Books on Demand, In de Tarpen 42, 22848 Norderstedt, info[at]bod[dot]de | Anbieter: preigu.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Infections with Chlamydia pneumoniae have been associated with chronic inflammatory diseases, but the influences of multiple factors are not well understood. A multivariate experimental design investigated the major factors that influence disease, chlamydial lung burden, and transcript levels: i) host genetics, ii) pre-challenge immunity, iii) time after challenge infection, iv) dietary protein content, v) dietary antioxidant content. The combined effects of mouse strain, immune status, and time after challenge inoculation resulted in opposite outcomes for lung disease and elimination of C. pneumoniae, while dietary protein and antioxidant content had little overall influence. A simple best-fit partial least square regression model using day-3 Tim3, GATA3, and arginase 2 transcript concentrations predicted 85% of the day-10 disease and 72% of the day-10 C. pneumoniae lung load. This book has elucidated general mechanisms of chlamydial pathogenesis, and clearly supports the concept that host-dependent levels of early Th1 and Th2 responses, and their balance, significantly correlated with late disease and pathogen load of C. pneumoniae lung infections. 116 pp. Englisch.…

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Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Infections with Chlamydia pneumoniae have been associated with chronic inflammatory diseases, but the influences of multiple factors are not well understood. A multivariate experimental design investigated the major factors that influence disease, chlamydial lung burden, and transcript levels: i) host genetics, ii) pre-challenge immunity, iii) time after challenge infection, iv) dietary protein content, v) dietary antioxidant content. The combined effects of mouse strain, immune status, and time after challenge inoculation resulted in opposite outcomes for lung disease and elimination of C. pneumoniae, while dietary protein and antioxidant content had little overall influence. A simple best-fit partial least square regression model using day-3 Tim3, GATA3, and arginase 2 transcript concentrations predicted 85% of the day-10 disease and 72% of the day-10 C. pneumoniae lung load. This book has elucidated general mechanisms of chlamydial pathogenesis, and clearly supports the concept that host-dependent levels of early Th1 and Th2 responses, and their balance, significantly correlated with late disease and pathogen load of C. pneumoniae lung infections.…

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Editorial: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Wang ChengmingChengming Wang received his PhD in Biomedical Sciences and a MS degree in Poultry Science from Auburn University. He obtained the MS degree in Veterinary Preventive Medicine from Nanjing Agricultural University and D.…

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Editorial: VDM Verlag Dr. Mueller Aktiengesellschaft & Co. KG, 2010
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Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Infections with Chlamydia pneumoniae have been associated with chronic inflammatory diseases, but the influences of multiple factors are not well understood. A multivariate experimental design investigated the major factors that influence disease, chlamydial lung burden, and transcript levels: i) host genetics, ii) pre-challenge immunity, iii) time after challenge infection, iv) dietary protein content, v) dietary antioxidant content. The combined effects of mouse strain, immune status, and time after challenge inoculation resulted in opposite outcomes for lung disease and elimination of C. pneumoniae, while dietary protein and antioxidant content had little overall influence. A simple best-fit partial least square regression model using day-3 Tim3, GATA3, and arginase 2 transcript concentrations predicted 85% of the day-10 disease and 72% of the day-10 C. pneumoniae lung load. This book has elucidated general mechanisms of chlamydial pathogenesis, and clearly supports the concept that host-dependent levels of early Th1 and Th2 responses, and their balance, significantly correlated with late disease and pathogen load of C. pneumoniae lung infections.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 116 pp. Englisch.…