9783642366475 - programmed cells from basic neuroscience to therapy: 20 (research and perspectives in neurosciences, 20) (9 resultados)

Idioma: Inglés
Editorial: Berlin, Springer Berlin. 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
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Librería: Universitätsbuchhandlung Herta Hold GmbH, Berlin, AlemaniaUniversitätsbuchhandlung Herta Hold GmbH
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EUR 12,00
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XII, 132 p. Hardcover. Versand aus Deutschland / We dispatch from Germany via Air Mail. Einband bestoßen, daher Mängelexemplar gestempelt, sonst sehr guter Zustand. Imperfect copy due to slightly bumped cover, apart from this in very good condition. Stamped. Stamped. Research and Perspectives in Neurosciences ; 20. Sprache: Engl…isch.

Idioma: Inglés
Editorial: Springer-Verlag GmbH 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
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Librería: Buchpark, Trebbin, AlemaniaBuchpark
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EUR 21,44
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Condición: Hervorragend. Zustand: Hervorragend | Sprache: Englisch | Produktart: Bücher | Keine Beschreibung verfügbar.

Programmed Cells from Basic Neuroscience to Therapy (Research and Perspectives in Neurosciences, 20)
Idioma: Inglés
Editorial: Springer 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
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Librería: Books Puddle, New York, NY, Estados Unidos de AmericaBooks Puddle
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EUR 213,59
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Condición: New. pp. 150.

Idioma: Inglés
Editorial: Springer, Berlin, Springer Berlin Heidelberg, Springer 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
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Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH
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EUR 162,91
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Buch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed our experimental landscape and opened new possibilities. The advances in PSC have provided an important…tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled environment. For example, reprogramming cells from patients with neurological diseases allows the study of molecular pathways particular to specific subtypes of neurons such as dopaminergic neurons in Parkinson's Disease, Motor neurons for Amyolateral Sclerosis or myelin for Multiple Sclerosis. Detecting disease-specific molecular signatures in live human brain cells, opens possibilities for early intervention therapies and new diagnostic tools. Importantly, once the neurological neural phenotype is detected in vitro, the so-called 'disease-in-a-dish' approach allows for the screening of drugs that can ameliorate the disease-specific phenotype. New therapeutic drugs could either act on generalized pathways in all patients or be patient-specific and used in a personalized medicine approach. However, there are a number of pressing issues that need to be addressed and resolved before PSC technology can be extensively used for clinically relevant modeling of neurological diseases. Among these issues are the variability in PSC generation methods, variability between individuals, epigenetic/genetic instability and the ability to obtain disease-relevant subtypes of neurons . Current protocols for differentiating PSC into specific subtypes of neurons are under development, but more and better protocols are needed. Understanding the molecular pathways involved in human neural differentiation will facilitate the development of methods and tools to enrich and monitor the generation of specific subtypes of neurons that would be more relevant in modeling differentneurological diseases.

Programmed Cells from Basic Neuroscience to Therapy (Research and Perspectives in Neurosciences, 20)
Idioma: Inglés
Editorial: Springer 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
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Librería: Mispah books, Redhill, SURRE, Reino UnidoMispah books
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EUR 247,05
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Hardcover. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Idioma: Inglés
Editorial: Berlin Springer Berlin Heidelberg Springer Jun 2013 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
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Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, AlemaniaBuchWeltWeit Ludwig Meier e.K.
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EUR 160,49
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Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed our experimental landscape and opened new possibilities. The advances in PSC have provid…ed an important tool for the study of human neuronal function as well as neurodegenerative and neurodevelopmental diseases in live human neurons in a controlled environment. For example, reprogramming cells from patients with neurological diseases allows the study of molecular pathways particular to specific subtypes of neurons such as dopaminergic neurons in Parkinson's Disease, Motor neurons for Amyolateral Sclerosis or myelin for Multiple Sclerosis. Detecting disease-specific molecular signatures in live human brain cells, opens possibilities for early intervention therapies and new diagnostic tools. Importantly, once the neurological neural phenotype is detected in vitro, the so-called 'disease-in-a-dish' approach allows for the screening of drugs that can ameliorate the disease-specific phenotype. New therapeutic drugs could either act on generalized pathways in all patients or be patient-specific and used in a personalized medicine approach. However, there are a number of pressing issues that need to be addressed and resolved before PSC technology can be extensively used for clinically relevant modeling of neurological diseases. Among these issues are the variability in PSC generation methods, variability between individuals, epigenetic/genetic instability and the ability to obtain disease-relevant subtypes of neurons . Current protocols for differentiating PSC into specific subtypes of neurons are under development, but more and better protocols are needed. Understanding the molecular pathways involved in human neural differentiation will facilitate the development of methods and tools to enrich and monitor the generation of specific subtypes of neurons that would be more relevant in modeling different neurological diseases. 130 pp. Englisch.

Idioma: Inglés
Editorial: Springer Berlin Heidelberg 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
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- Impresión bajo demanda
Librería: moluna, Greven, Alemaniamoluna
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EUR 137,26
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Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Presents latest research on neurodegenerative diseases Presents prospects for novel therapies Written by leading experts in the field Presents latest research on neurodegenerative diseasesPresents prospects…for novel thera.

Programmed Cells from Basic Neuroscience to Therapy (Research and Perspectives in Neurosciences, 20)
Idioma: Inglés
Editorial: Springer 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
- Tapa dura
- Impresión bajo demanda
Librería: Majestic Books, Hounslow, Reino UnidoMajestic Books
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EUR 226,92
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Condición: New. Print on Demand pp. 150.

Programmed Cells from Basic Neuroscience to Therapy (Research and Perspectives in Neurosciences, 20)
Idioma: Inglés
Editorial: Springer 2013
Serie: Research and Perspectives in Neurosciences, Libro 10 de 14. Libro 10 de 14 - Research and Perspectives in Neurosciences
- Tapa dura
- Impresión bajo demanda
Librería: Biblios, frankfurt am main, HESSE, AlemaniaBiblios
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EUR 225,35
Envío por EUR 9,95Se envía de Alemania a Estados Unidos de AmericaCantidad disponible: 4 disponibles
Condición: New. PRINT ON DEMAND pp. 150.