Isbn: 9783639255683 - inside the plasma amine oxidase: preliminary drug discovery study of plasma amine oxidase: structural basis of substrate and inhibitory activity of bovine plasma amine oxidase (6 resultados)

Condición: New. pp. 216.

Taschenbuch. Condición: Neu. INSIDE THE PLASMA AMINE OXIDASE | PRELIMINARY DRUG DISCOVERY STUDY OF PLASMA AMINE OXIDASE: STRUCTURAL BASIS OF SUBSTRATE AND INHIBITORY ACTIVITY OF BOVINE PLASMA AMINE OXIDASE | Yanwen Chen | Taschenbuch | Englisch | VDM Verlag Dr. Müller | EAN 9783639255683 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Chen YanwenYanwen Chen received her Bachelor of Science in Chemistry degree from Nanjing University in 1996, a Master of Science in Chemistry degree at Chinese Acedamy of Science (Beijing) in 2000, and Ph.D. in Chemistry from Case We.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - The copper-containing amine oxidases, like bovine plasma amine oxidase (BPAO), carry out a transaminative oxidation of primary amines to aldehydes via use of an active site Tyr-derived 2,4,5-trihydroxyphenylalanine quinone (TPQ) cofactor. Propargylamine is a potent inactivator of BPAO (IC50 = 3 µM), possibly through active-site modification by the a,ß-unsaturated aldehyde turnover product, but the simple structure is expected to confer low selectivity. On the basis of the finding by previous students that certain extended conjugation analogs such as 1,6-diamino-2,4- hexadiyne and 3-cyanopropargylamine preserve strong inactivation potency, other extended conjugation analogs of propargylamine were evaluated. In particular, 1-amino-2,4-hexadiynes with a 6-OH rather than 6-NH2 group were found to be potent inhibitors.…

Condición: New. Print on Demand pp. 216 2:B&W 6 x 9 in or 229 x 152 mm Perfect Bound on Creme w/Gloss Lam.

Condición: New. PRINT ON DEMAND pp. 216.