9783540646747 - the reeler mouse as a model of brain development: 150 (advances in anatomy, embryology and cell biology, 150) de goffinet, andre m.; lambert de rouvroit, catherine (8 resultados)

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Editorial: Springer 1998
Serie: Advances in Anatomy, Embryology and Cell Biology, Libro 142 de 173. Libro 142 de 173 - Advances in Anatomy, Embryology and Cell Biology
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Serie: Advances in Anatomy, Embryology and Cell Biology, Libro 142 de 173. Libro 142 de 173 - Advances in Anatomy, Embryology and Cell Biology
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The Reeler Mouse as a Model of Brain Development
Lambert de Rouvroit, Catherine (Author)/ Goffinet, Andre M. (Author)
Idioma: Inglés
Editorial: Springer 1998
Serie: Advances in Anatomy, Embryology and Cell Biology, Libro 142 de 173. Libro 142 de 173 - Advances in Anatomy, Embryology and Cell Biology
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Librería: Revaluation Books, Exeter, , Reino UnidoRevaluation Books
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Paperback. Condición: Brand New. 108 pages. 9.50x6.25x0.25 inches. In Stock.

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Serie: Advances in Anatomy, Embryology and Cell Biology, Libro 142 de 173. Libro 142 de 173 - Advances in Anatomy, Embryology and Cell Biology
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Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Only five years ago, nobody in his right mind would have consid ered publishing a book on reeler as a model for brain develop ment. Although this interesting mutation has been with us for half a century, it is fair to say that, in spite of a wave o…f enthusiasm in the late sixties and early seventies, generated primarily by Sidman, Caviness and colleagues, studies of reeler mice fell pro gressively out of fashion during the next two decades. All that changed almost overnight when the cloning of the reeler gene, dubbed reelin, was reported in Tom Curran's laboratory in 1995. The fact that the same gene was identified at the same time independently by two other groups using positional cloning sug gested strongly that reelin was the right candidate. Although the key experiments of transgenic rescue have not been made (and perhaps will never be), the equation 'reeler is reelin' has been established beyond reasonable doubt, as alterations of the reelin gene and/or its expression have been found in at least five alleles of reeler and in the mutation Shaking Rat Kawasaki (SRK), an ortholog of reeler.

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Editorial: Springer Berlin Heidelberg, Springer Berlin Heidelberg Sep 1998 1998
Serie: Advances in Anatomy, Embryology and Cell Biology, Libro 142 de 173. Libro 142 de 173 - Advances in Anatomy, Embryology and Cell Biology
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Librería: BuchWeltWeit Ludwig Meier e.K., Bergisch Gladbach, , AlemaniaBuchWeltWeit Ludwig Meier e.K.
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Only five years ago, nobody in his right mind would have consid ered publishing a book on reeler as a model for brain develop ment. Although this interesting mutation has been with us for half a century, it is fair to say that, in s…pite of a wave of enthusiasm in the late sixties and early seventies, generated primarily by Sidman, Caviness and colleagues, studies of reeler mice fell pro gressively out of fashion during the next two decades. All that changed almost overnight when the cloning of the reeler gene, dubbed reelin, was reported in Tom Curran's laboratory in 1995. The fact that the same gene was identified at the same time independently by two other groups using positional cloning sug gested strongly that reelin was the right candidate. Although the key experiments of transgenic rescue have not been made (and perhaps will never be), the equation 'reeler is reelin' has been established beyond reasonable doubt, as alterations of the reelin gene and/or its expression have been found in at least five alleles of reeler and in the mutation Shaking Rat Kawasaki (SRK), an ortholog of reeler. 124 pp. Englisch.

Idioma: Inglés
Editorial: Springer, Springer Sep 1998 1998
Serie: Advances in Anatomy, Embryology and Cell Biology, Libro 142 de 173. Libro 142 de 173 - Advances in Anatomy, Embryology and Cell Biology
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Librería: buchversandmimpf2000, Emtmannsberg, BAYE, Alemaniabuchversandmimpf2000
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Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Only five years ago, nobody in his right mind would have consid ered publishing a book on reeler as a model for brain develop ment. Although this interesting mutation has been with us for half a century, it is fair to say that, in spite… of a wave of enthusiasm in the late sixties and early seventies, generated primarily by Sidman, Caviness and colleagues, studies of reeler mice fell pro gressively out of fashion during the next two decades. All that changed almost overnight when the cloning of the reeler gene, dubbed reelin, was reported in Tom Curran's laboratory in 1995. The fact that the same gene was identified at the same time independently by two other groups using positional cloning sug gested strongly that reelin was the right candidate. Although the key experiments of transgenic rescue have not been made (and perhaps will never be), the equation 'reeler is reelin' has been established beyond reasonable doubt, as alterations of the reelin gene and/or its expression have been found in at least five alleles of reeler and in the mutation Shaking Rat Kawasaki (SRK), an ortholog of reeler.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 124 pp. Englisch.