ISBN: 9783527351008 - rna as a drug target: the next frontier for medicinal chemistry (methods & principles in medicinal chemistry) (30 resultados)

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    Editorial: Wiley-VCH, 2024

    3527351000 / 9783527351008

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    Hardcover. Condición: new. Hardcover. Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: A complete toolbox for working with RNA, from structure determination to screening and lead generation techniquesA wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and moreAuthoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry. Shipping may be from multiple locations in the US or from the UK, depending on stock availability. …

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    Condición: New. In English.

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    Buch. Condición: Neu. Neuware - Provides the concepts and tools for developing drug-like small molecules that selectively target RNA rather than proteins, including the first successful examples from the development pipeline of big pharma.

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    Condición: New. 2024. 1st Edition. hardcover. . . . . . Books ship from the US and Ireland.

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    Hardback. Condición: New. Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: A complete "toolbox" for working with RNA, from structure determination to screening and lead generation techniquesA wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and moreAuthoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.…

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    Buch. Condición: Neu. RNA as a Drug Target | The Next Frontier for Medicinal Chemistry | John Schneekloth (u. a.) | Buch | Methods and Principles in Medicinal Chemistry | 416 S. | Englisch | 2024 | Wiley-VCH GmbH | EAN 9783527351008 | Verantwortliche Person für die EU: Wiley-VCH GmbH, Boschstr. 12, 69469 Weinheim, product-safety[at]wiley[dot]com | Anbieter: preigu. …

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    Buch. Condición: Neu. Neuware -Provides the concepts and tools for developing drug-like small molecules that selectively target RNA rather than proteins, including the first successful examples from the development pipeline of big pharma. Englisch.

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    Buch. Condición: Neu. Neuware -Provides the concepts and tools for developing drug-like small molecules that selectively target RNA rather than proteins, including the first successful examples from the development pipeline of big pharma. Englisch.

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    Buch. Condición: Neu. Neuware -Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: - A complete 'toolbox' for working with RNA, from structure determination to screening and lead generation techniques - A wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more - Authoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.…

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    Condición: New. 1st edition NO-PA16APR2015-KAP.

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    Buch. Condición: Neu. Neuware -Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugsWiley-VCH GmbH, Boschstraße 12, 69469 Weinheim 392 pp. Englisch.

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    Hardback. Condición: New. Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: A complete "toolbox" for working with RNA, from structure determination to screening and lead generation techniquesA wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and moreAuthoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry.…

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    Hardcover. Condición: new. Hardcover. Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: A complete toolbox for working with RNA, from structure determination to screening and lead generation techniquesA wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and moreAuthoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry. Shipping may be from our Sydney, NSW warehouse or from our UK or US warehouse, depending on stock availability. …

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    Hardcover. Condición: New. 1st Edition.

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    Buch. Condición: Neu. Neuware -Discover a new paradigm in drug discovery that greatly expands the space of addressable drug targets and potential novel drugs Existing paradigms for drug discovery have focused largely on enzymes and other proteins as drug targets. In recent years, however, different varieties of ribonucleic acids have emerged as a viable focus for target-based drug discovery, with the potential to revolutionize the strategy and approach for this essential step in the drug development process. RNA as a Drug Target: The Next Frontier for Medicinal Chemistry offers a practice-oriented introduction to developing drug-like small molecules that selectively modulate both coding and non-coding RNAs. Beginning with a description and characterization of existing druggable RNAs, the book discusses how to approach different RNA targets for drug discovery. The result is a crucial resource for targeting RNAs and creating the next generation of life-saving pharmaceuticals. RNA as a Drug Target readers will also find: - A complete 'toolbox' for working with RNA, from structure determination to screening and lead generation techniques - A wide range of addressable targets and mechanisms, including splicing modulation, riboswitches, targeted degradation, and more - Authoritative discussion of the potential of RNA-targeted small molecule therapeutics for drugging the epitranscriptome RNA as a Drug Target provides an expert introduction to a new frontier in pharmaceutical research for medicinal chemists, biochemists, molecular biologists, and members of the pharmaceutical industry. Englisch.…

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    Condición: New. John Schneekloth received his undergraduate degree from Dartmouth College in 2001 where he worked with Prof. Gordon Gribble. He then moved to Yale University and obtained a Ph.D. from the chemistry department with Prof. Craig Crews in 2006. As a graduate st.

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    Hardcover. Condición: Brand New. 236 pages. 9.61x6.69x9.61 inches. In Stock. This item is printed on demand.