ISBN: 9781848163386 - protein-protein complexes: analysis, modeling and drug design (20 resultados)

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Gebunden. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. This book includes review chapters on the characterization of protein-protein interfaces, structure determination of pr.…

Buch. Condición: Neu. PROTEIN-PROTEIN COMPLEXES | Zacharias Martin | Buch | Gebunden | Englisch | 2010 | ICP | EAN 9781848163386 | Verantwortliche Person für die EU: Libri GmbH, Europaallee 1, 36244 Bad Hersfeld, gpsr[at]libri[dot]de | Anbieter: preigu Print on Demand.

Buch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Given the immense progress achieved in elucidating protein-protein complex structures and in the field of protein interaction modeling, there is great demand for a book that gives interested researchers/students a comprehensive overview of the field. This book does just that. It focuses on what can be learned about protein-protein interactions from the analysis of protein-protein complex structures and interfaces. What are the driving forces for protein-protein association How can we extract the mechanism of specific recognition from studying protein-protein interfaces How can this knowledge be used to predict and design protein-protein interactions (interaction regions and complex structures) What methods are currently employed to design protein-protein interactions, and how can we influence protein-protein interactions by mutagenesis and small-molecule drugs or peptide mimetics The book consists of about 15 review chapters, written by experts, on the characterization of protein-protein interfaces, structure determination of protein complexes (by NMR and X-ray), theory of protein-protein binding, dynamics of protein interfaces, bioinformatics methods to predict interaction regions, and prediction of protein-protein complex structures (docking and homology modeling of complexes, etc.) and design of protein-protein interactions. It serves as a bridge between studying/analyzing protein-protein complex structures (interfaces), predicting interactions, and influencing/designing interactions.…