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Crc press dez 2020 (82 resultados)

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  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367160919 / 9780367160913

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 63,81

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    Taschenbuch. Condición: Neu. Neuware - This book analyzes the implications of the trend toward increased seller concentration due to mergers and leveraged buyouts that have helped increase food firm stock prices 900' during the 1980s. It is an essential reading for industrial organization economists and agricultural marketing economists.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367166119 / 9780367166113

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    EUR 63,94

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    Taschenbuch. Condición: Neu. Neuware - This book examines the rationale for emphasizing productivity as the dominant goal of agricultural research and challenges in the form of alternative goals that scientists might seek in performing agricultural research. It presents bibliographic essays that review the criticisms of research.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367159759 / 9780367159757

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 64,06

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    Taschenbuch. Condición: Neu. Neuware - This book is concerned with the paradigm shifts occurring in U.S. agriculture and its related financial services sector. It explains the major challenges and opportunities confronting those firms that lend to agricultural producers and agribusinesses as they prepare for the twenty-first century.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367158590 / 9780367158590

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    EUR 64,06

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    Taschenbuch. Condición: Neu. Neuware - This book discusses pesticide production, distribution, and use; the problems caused by pests and pesticides; and the role of integrated pest management in minimizing these problems. It addresses the relationship of the farmers' practices and attitudes to the development of pest management systems.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367158272 / 9780367158279

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    Taschenbuch. Condición: Neu. Neuware - This book discusses the history and economics, biology and ecology, behavior, pheromones and other semiochemicals, physiology, and biochemistry of fire ants and leaf-cutting ants. It illustrates new approaches to control these ants by innovative research on anti-feedant chemicals from plants.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367670569 / 9780367670566

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    EUR 69,19

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    Taschenbuch. Condición: Neu. Neuware - AI is an integral part of every video game and this book helps game developers keep up with the constantly evolving technological advances to create robust AI. The authors draw on their considerable experience and uses case studies from real games to provide a complete reference. Also included are exercises so readers can test their comprehension and understanding of the concepts and practices presented.This revised and updated Third Edition includes new techniques, algorithms, data structures and representations needed to create powerful AI in games. It helps experienced game developers learn new techniques and provides students with a solid understanding of game AI that will help them jumpstart their careers.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367166801 / 9780367166809

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    EUR 85,61

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    Taschenbuch. Condición: Neu. Neuware - This monograph provides information on the basic and applied research on the morphology, taxonomy, biology, ecology and behaviour of the whitefly, Bemisia tabaci (Gennadius). It is devoted to the epidemiology of the diseases transmitted by the whitefly and the approaches to control.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367161915 / 9780367161910

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 87,44

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    Taschenbuch. Condición: Neu. Neuware - This book is the outcome of a conference on 'Empirical Studies of Industrial Organization and Trade in the Food Industries' in Indianapolis. The conference placed an emphasis on empirical applications of new methods linking industrial organization and trade theory for the U.S. food industries.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367162954 / 9780367162955

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    EUR 87,57

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    Taschenbuch. Condición: Neu. Neuware - This book provides the foundation needed to understand, interpret, and analyze farm policy. It rests on the proposition that farm policy can be studied properly only when it is placed within its social, economic, and political setting.

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367166313 / 9780367166311

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 87,64

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    Taschenbuch. Condición: Neu. Neuware - This book presents information on the direct effects of increased atmospheric CO2 on plants. It considers what we already know about plant responses to various CO2 concentrations. .

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367165872 / 9780367165871

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    EUR 87,64

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    Taschenbuch. Condición: Neu. Neuware - This book is based on an informal conference, 'Diversity in the Genus Apis,' which took place in 1989 at the annual meeting of the Entomological Society of America. It serves as an introduction to various aspects of honey bee biology and as a guide for future research especially on Asian honey bees.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367161648 / 9780367161644

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    Taschenbuch. Condición: Neu. Neuware - This book outlines the most important organizational, institutional, technical, and macroeconomic aspects of soil and land management appraisal. It discusses a broad range of important issues involved in designing and implementing more effective soil conservation programs. .…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367731940 / 9780367731946

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    EUR 97,88

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    Taschenbuch. Condición: Neu. Neuware - This practical guide provides the best introduction to large deformation material point method (MPM) simulations for geotechnical engineering. It provides the basic theory, discusses the different numerical features used in large deformation simulations, and presents a number of applications -- providing references, examples and guidance when using MPM for practical applications.MPM covers problems in static and dynamic situations within a common framework. It also opens new frontiers in geotechnical modelling and numerical analysis. It represents a powerful tool for exploring large deformation behaviours of soils, structures and fluids, and their interactions, such as internal and external erosion, and post-liquefaction analysis; for instance the post-failure liquid-like behaviours of landslides, penetration problems such as CPT and pile installation, and scouring problems related to underwater pipelines. In the recent years, MPM has developed enough for its practical use in industry, apart from the increasing interest in the academic world.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    036773656X / 9780367736569

    Serie: Libro 4 de 12 - Routledge Studies in International Real Estate

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 97,97

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    Taschenbuch. Condición: Neu. Neuware - Since the start of the twenty-first century, urban communities have faced increasing challenges in housing affordability, with environmental issues causing additional concern. It is clear that changes to urban housing are needed to enhance the resilience of cities and improve the economic, social and physical well-being of residents. This book provides a comparative cross-national perspective on urban housing and sustainability in Europe, exploring the key barriers and drivers associated with sustainable urban development and community regeneration.Country-specific chapters allow for easy comparison, with each summarizing how sustainable housing operates in the country in question, before going on to discuss the key barriers and drivers at play. This book brings a sustainability perspective to the comparative housing literature which frequently fails to integrate the social, economic and environmental pillars of sustainability. The book outlines many of the changes that professionals and residents will need to make to their practices and cultures in order to enhance housing resilience. Students, researchers and professionals with an interest in sustainable housing creation and regeneration will find this book an invaluable reference.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367736985 / 9780367736989

    Serie: Libro 5 de 5 - Protein Science

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 98,04

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    Taschenbuch. Condición: Neu. Neuware - Most clinical laboratory tests utilize interstitial and extravascular such as blood, urine, cerebral spinal fluid (CSF), and saliva. For example, CSF is monitored in the context of cancer for both diagnostic and therapeutic reasons. And yet, our understanding of the makeup of interstitial fluids, their relationships to disease, as well as their commercial importance in therapeutics and diagnostics remains rudimentary. Although sometimes perceived as static, interstitial and extravascular fluids are surprisingly dynamic. More than half of serum albumin is in the extravascular space. These fluids move rapidly between the intravascular and extravascular spaces - one entire plasma volume is exchanged very nine hours. In the first half of the book, the authors cover fundamental concepts of interstitial fluids, including their composition and function. They then further review the mechanisms by which interstitial fluids are regulated, characterizing the importance of hyaluronan - a major constituent of interstitial spaces and an a component of synovial fluid; and, outlining the regulation of proteolysis in the interstitial space. In the second half of the book, the authors focus on the coagulation system. This system has been studied extensively in the context of vascular spaces. But many of its components exist in the interstitial spaces. Chapters are devoted to the fibrinolytic system, kallikrein, matrix metalloproteinases, coagulation factors, and protease inhibitors - all are interstitial. By covering a unique array of topics with broad application to biomedical scientists, this book expands our understanding of the importance of interstitial spaces and the fluids that move through and reside in this extravascular environment.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367735792 / 9780367735791

    Serie: Libro 24 de 35 - Spon Research

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    Condición: Nuevo

    EUR 98,38

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    Taschenbuch. Condición: Neu. Neuware - This book seeks to enhance understanding of the impacts of project setup and its implementation environment on project performance by leveraging information from the study of a rich set of European transport infrastructure project cases. It puts forward a system's view of project delivery and aims to serve as a strategic tool for decision makers and practitioners. The proposed approach is not limited to specific stakeholder views. On the contrary, it allows stakeholders to formulate their own strategies based on an holistic set of potential implementation scenarios.Furthermore, by including cases of projects that have been influenced by the recent financial crisis, the book aims to capitalise on experiences and provide guidelines as to the design and implementation of resilient projects delivered both through traditional as well as Public Private Partnership (PPP) models.Finally, the book proposes a new Transport Infrastructure Resilience Indicator and a corresponding project rating system that can be assessed with an eye to the future, ultimately aiming to support the successful delivery of transport infrastructure projects for all stakeholders involved.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367732912 / 9780367732912

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 98,38

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    Taschenbuch. Condición: Neu. Neuware - Circulant matrices have been around for a long time and have been extensively used in many scientific areas. This book studies the properties of the eigenvalues for various types of circulant matrices, such as the usual circulant, the reverse circulant, and the k-circulant when the dimension of the matrices grow and the entries are random. In particular, the behavior of the spectral distribution, of the spectral radius and of the appropriate point processes are developed systematically using the method of moments and the various powerful normal approximation results. This behavior varies according as the entries are independent, are from a linear process, and are light- or heavy-tailed. Arup Bose obtained his B.Stat., M.Stat. and Ph.D. degrees from the Indian Statistical Institute. He has been on its faculty at the Theoretical Statistics and Mathematics Unit, Kolkata, India since 1991. He is a Fellow of the Institute of Mathematical Statistics, and of all three national science academies of India. He is a recipient of the S.S. Bhatnagar Prize and the C.R. Rao Award. He is the author of three books: Patterned Random Matrices, Large Covariance and Autocovariance Matrices (with Monika Bhattacharjee) and U-Statistics, M_m-Estimators and Resampling (with Snigdhansu Chatterjee). Koushik Saha obtained a B.Sc. in Mathematics from Ramakrishna Mission Vidyamandiara, Belur and an M.Sc. in Mathematics from Indian Institute of Technology Bombay. He obtained his Ph.D. degree from the Indian Statistical Institute under the supervision of Arup Bose. His thesis on circulant matrices received high praise from the reviewers. He has been on the faculty of the Department of Mathematics, Indian Institute of Technology Bombay since 2014.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367735652 / 9780367735654

    Serie: Libro 5 de 10 - Routledge Complex Real Property Rights Series

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    EUR 98,49

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    Taschenbuch. Condición: Neu. Neuware - This book takes the concept of piracy as a starting point to discuss the instability of property as a social construction and how this is spatially situated. Piracy is understood as acts and practices that emerge in zones where the construction and definition of property is ambiguous. Media piracy is a frequently used example where file-sharers and copyright holders argue whether culture and information is a common resource to be freely shared or property to be protected. This book highlights that this is not a dilemma unique to immaterial resources: concepts such as property, ownership and the rights of use are just as diffuse when it comes to spatial resources such as land, water, air or urban space. By structuring the book around this heterogeneous understanding of piracy as an analytical perspective, the editors and contributors advance a trans-disciplinary and multi-theoretical approach to place and property. In doing so, the book moves from theoretical discussions on commons and property to empirical cases concerning access to and appropriation of land, natural and cultural resources. The chapters cover areas such as maritime piracy, the philosophical and legal foundations of property rights, mining and land rights, biopiracy and traditional knowledge, indigenous rights, colonization of space, military expansionism and the enclosure of urban space. This book is essential reading for a variety of disciplines including indigenous studies, cultural studies, geography, political economy, law, environmental studies and all readers concerned with piracy and the ambiguity of property.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367737191 / 9780367737191

    Serie: Libro 3 de 12 - Routledge Studies in International Real Estate

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 98,69

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    Taschenbuch. Condición: Neu. Neuware - This book explores how econometric modelling can be used to provide valuable insight into international housing markets. Initially describing the role of econometrics modelling in real estate market research and how it has developed in recent years, the book goes on to compare and contrast the impact of various macroeconomic factors on developed and developing housing markets. Explaining the similarities and differences in the impact of financial crises on housing markets around the world, the author's econometric analysis of housing markets across the world provides a broad and nuanced perspective on the impact of both international financial markets and local macro economy on housing markets. With discussion of countries such as China, Germany, UK, US and South Africa, the lessons learned will be of interest to scholars of Real Estate economics around the world.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367734311 / 9780367734312

    Serie: Libro 39 de 71 - Chapman and Hall/CRC Financial Mathematics

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    EUR 99,14

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    Taschenbuch. Condición: Neu. Neuware - The book will be devoted to quantitative models and computational techniques for risk management of equity-linked insurance. Although there have been research papers on the valuation of a great variety of investment guarantee products, they were primarily based on financial option pricing theory from the policyholders' perspective. This book is.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367731711 / 9780367731717

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    Condición: Nuevo

    EUR 87,15

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    Taschenbuch. Condición: Neu. Neuware - Nail disorders are a specialized group of disorders which are often neglected during post graduate teaching. This book aims to provide a comprehensive review covering the diagnostic and therapeutic aspects of nail disorders. It discusses the basics of nail unit, common conditions like infections, tumors and genetic diseases, diagnostic armamentarium involved in nail diseases like KOH mount, onychoscopy, imaging and surgical management of nail diseases which includes anesthesia of nail unit, nail biopsy and advanced nail procedures including video demonstration of such procedures. This book elaborates on nails in systemic diseases and briefly covers nail cosmetics and nail photography.Key Features - Comprehensively reviews nail disorders - Includes diagnosis, therapeutic and surgical aspect - Discusses Onychoscopy - Reviews the importance of nail photography.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    036773432X / 9780367734329

    Serie: Libro 90 de 155 - Chapman & Hall/CRC Biostatistics

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    EUR 99,60

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    Taschenbuch. Condición: Neu. Neuware - Statistical Methods for Survival Trial Design: With Applications to Cancer Clinical Trials Using R provides a thorough presentation of the principles of designing and monitoring cancer clinical trials in which time-to-event is the primary endpoint. Traditional cancer trial designs with time-to-event endpoints are often limited to the exponential model or proportional hazards model. In practice, however, those model assumptions may not be satisfied for long-term survival trials. This book is the first to cover comprehensively the many newly developed methodologies for survival trial design, including trial design under the Weibull survival models; extensions of the sample size calculations under the proportional hazard models; and trial design under mixture cure models, complex survival models, Cox regression models, and competing-risk models. A general sequential procedure based on the sequential conditional probability ratio test is also implemented for survival trial monitoring. All methodologies are presented with sufficient detail for interested researchers or graduate students.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367738058 / 9780367738051

    Serie: Libro 52 de 155 - Chapman & Hall/CRC Biostatistics

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    EUR 99,60

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    Taschenbuch. Condición: Neu. Neuware - Data Analysis with Competing Risks and Intermediate States explains when and how to use models and techniques for the analysis of competing risks and intermediate states. It covers the most recent insights on estimation techniques and discusses in detail how to interpret the obtained results.After introducing example studies from the biomedical and epidemiological fields, the book formally defines the concepts that play a role in analyses with competing risks and intermediate states. It addresses nonparametric estimation of the relevant quantities. The book then shows how to use a stacked data set that offers great flexibility in the modeling of covariable effects on the transition rates between states. It also describes three ways to quantify effects on the cumulative scale.Each chapter includes standard exercises that reflect on the concepts presented, a section on software that explains options in SAS and Stata and the functionality in the R program, and computer practicals that allow readers to practice with the techniques using an existing data set of bone marrow transplant patients. The book's website provides the R code for the computer practicals along with other material.For researchers with some experience in the analysis of standard time-to-event data, this practical and thorough treatment extends their knowledge and skills to the competing risks and multi-state settings. Researchers from other fields can also easily translate individuals and diseases to units and phenomena from their own areas.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367735539 / 9780367735531

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 99,62

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    Taschenbuch. Condición: Neu. Neuware - Analyzing Health Data in R for SAS Users is aimed at helping health data analysts who use SAS accomplish some of the same tasks in R. It is targeted to public health students and professionals who have a background in biostatistics and SAS software, but are new to R. For professors, it is useful as a textbook for a descriptive or regression modeling class, as it uses a publicly-available dataset for examples, and provides exercises at the end of each chapter. For students and public health professionals, not only is it a gentle introduction to R, but it can serve as a guide to developing the results for a research report using R software.Features: - Gives examples in both SAS and R - Demonstrates descriptive statistics as well as linear and logistic regression - Provides exercise questions and answers at the end of each chapter - Uses examples from the publicly available dataset, Behavioral Risk Factor Surveillance System (BRFSS) 2014 data - Guides the reader on producing a health analysis that could be published as a research report - Gives an example of hypothesis-driven data analysis - Provides examples of plots with a color insert.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367731878 / 9780367731878

    Serie: Libro 94 de 155 - Chapman & Hall/CRC Biostatistics

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    Condición: Nuevo

    EUR 99,68

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    Taschenbuch. Condición: Neu. Neuware - Cost-effectiveness analysis is becoming an increasingly important tool for decision making in the health systems. Cost-Effectiveness of Medical Treatments formulates the cost-effectiveness analysis as a statistical decision problem, identifies the sources of uncertainty of the problem, and gives an overview of the frequentist and Bayesian statistical approaches for decision making. Basic notions on decision theory such as space of decisions, space of nature, utility function of a decision and optimal decisions, are explained in detail using easy to read mathematics.Features - Focuses on cost-effectiveness analysis as a statistical decision problem and applies the well-established optimal statistical decision methodology. - Discusses utility functions for cost-effectiveness analysis. - Enlarges the class of models typically used in cost-effectiveness analysis with the incorporation of linear models to account for covariates of the patients. This permits the formulation of the group (or subgroup) theory. - Provides Bayesian procedures to account for model uncertainty in variable selection for linear models and in clustering for models for heterogeneous data. Model uncertainty in cost-effectiveness analysis has not been considered in the literature. - Illustrates examples with real data. - In order to facilitate the practical implementation of real datasets, provides the codes in Mathematica for the proposed methodology. The motivation for the book is to make the achievements in cost-effectiveness analysis accessible to health providers, who need to make optimal decisions, to the practitioners and to the students of health sciences. Elías Moreno is Professor of Statistics and Operational Research at the University of Granada, Spain, Corresponding Member of the Royal Academy of Sciences of Spain, and elect member of ISI. Francisco José Vázquez-Polo is Professor of Mathematics and Bayesian Methods at the University of Las Palmas de Gran Canaria, and Head of the Department of Quantitative Methods. Miguel Ángel Negrín is Senior Lecturer in the Department of Quantitative Methods at the ULPGC. His main research topics are Bayesian methods applied to Health Economics, economic evaluation and cost-effectiveness analysis, meta-analysis and equity in the provision of healthcare services.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    036773561X / 9780367735616

    Serie: Libro 85 de 155 - Chapman & Hall/CRC Biostatistics

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    Taschenbuch. Condición: Neu. Neuware - Randomization, Masking, and Allocation Concealment is indispensable for any trial researcher who wants to use state of the art randomization methods, and also wants to be able to describe these methods correctly.Far too often the subtle nuances that distinguish proper randomization from flawed randomization are completely ignored in trial reports that state only that randomization was used, with no additional information. Experience has shown that in many cases, the type of randomization that was used was flawed. It is only a matter of time before medical journals and regulatory agencies come to realize that we can no longer rely on (or publish) flawed trials, and that flawed randomization in and of itself disqualifies a trial from being robust or high quality, even if that trial is of high quality otherwise.This book will help to clarify the role randomization plays in ensuring internal validity, and in drawing valid inferences from the data. The various chapters cover a variety of randomization methods, and are not limited to the most common (and most flawed) ones. Readers will come away with a profound understanding of what constitutes a valid randomization procedure, so that they can distinguish the valid from the flawed among not only existing methods but also methods yet to be developed.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367736705 / 9780367736705

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    Taschenbuch. Condición: Neu. Neuware - Instrumentation, Measurements, and Experiments in Fluids, Second Edition is primarily focused on essentials required for experimentation in fluids, explaining basic principles, and addressing the tools and methods needed for advanced experimentation. It also provides insight into the vital topics and issues associated with the devices and instruments used for fluid mechanics and gas dynamics experiments. The second edition adds exercise problems with answers, along with PIV systems of flow visualization, water flow channel for flow visualization, and pictures with Schlieren and shadowgraph-from which possible quantitative information can be extracted. Ancillary materials include detailed solutions manual and lecture slides for the instructors.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367738430 / 9780367738433

    Serie: Libro 49 de 155 - Chapman & Hall/CRC Biostatistics

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    Taschenbuch. Condición: Neu. Neuware - Design and Analysis of Clinical Trials for Predictive Medicine provides statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics-from identifying molecular biomarkers using DNA microarrays to confirming their clinical utility in randomized clinical trials. The foundation of modern clinical trials was laid many years before modern developments in biotechnology and genomics. Drug development in many diseases is now shifting to molecularly targeted treatment. Confronted with such a major break in the evolution toward personalized or predictive medicine, the methodologies for design and analysis of clinical trials is now evolving. This book is one of the first attempts to contribute to this evolution by laying a foundation for the use of appropriate statistical designs and methods in future clinical trials for predictive medicine. It is a useful resource for clinical biostatisticians, researchers focusing on predictive medicine, clinical investigators, translational scientists, and graduate biostatistics students.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367740044 / 9780367740047

    Serie: Libro 50 de 110 - ISSN

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    Taschenbuch. Condición: Neu. Neuware - Sequential Analysis: Hypothesis Testing and Changepoint Detection systematically develops the theory of sequential hypothesis testing and quickest changepoint detection. It also describes important applications in which theoretical results can be used efficiently. The book reviews recent accomplishments in hypothesis testing and changepoint detection both in decision-theoretic (Bayesian) and non-decision-theoretic (non-Bayesian) contexts. The authors not only emphasize traditional binary hypotheses but also substantially more difficult multiple decision problems. They address scenarios with simple hypotheses and more realistic cases of two and finitely many composite hypotheses. The book primarily focuses on practical discrete-time models, with certain continuous-time models also examined when general results can be obtained very similarly in both cases. It treats both conventional i.i.d. and general non-i.i.d. stochastic models in detail, including Markov, hidden Markov, state-space, regression, and autoregression models. Rigorous proofs are given for the most important results.Written by leading authorities in the field, this book covers the theoretical developments and applications of sequential hypothesis testing and sequential quickest changepoint detection in a wide range of engineering and environmental domains. It explains how the theoretical aspects influence the hypothesis testing and changepoint detection problems as well as the design of algorithms.…

  • Idioma: Inglés

    Editorial: CRC Press Dez 2020, 2020

    0367737221 / 9780367737221

    Serie: Libro 69 de 155 - Chapman & Hall/CRC Biostatistics

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    EUR 109,81

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    Taschenbuch. Condición: Neu. Neuware - In a global clinical development strategy, multiregional clinical trials (MRCTs) are vital in the development of innovative medicines. Multiregional Clinical Trials for Simultaneous Global New Drug Development presents a comprehensive overview on the current status of conducting MRCTs in clinical development. International experts from academia, industry, and health organizations address various aspects of the important problems in global clinical development and MRCTs. The book first provides a high-level introduction to the context, motivation, opportunities, and challenges in simultaneous global clinical development using MRCTs. It then focuses on the design, monitoring, and analysis/interpretation of MRCTs. The book concludes with an examination of the latest research topics from MRCT perspectives, such as special considerations by local health authorities, health economic evaluations, benefit-risk assessment, and medical devices.Explaining how to design, conduct, and interpret MRCTs, this book will help biostatisticians working in the late-stage clinical development of medical products. It will also be useful for statisticians and clinicians in the biopharmaceutical industry, regulatory agencies, and medical research institutes.…