Hyder mirghani (54 resultados)

Paperback or Softback. Condición: New. The interaction of type 2 diabetes, type 3 diabetes (Alzheimer's disease), and thegut microbiota. Book.

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Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Literature Review from the year 2017 in the subject Medicine - Internal Medicine, grade: C, , language: English, abstract: Dementia is a multifaceted syndrome with a significant public health, social, and economic burden; there are forty-four million people affected by the disease worldwide according to the most recent estimate.The number is projected to double by the year 2030 and to triple by 2050.Alzheimer's disease (AD, or type-3 diabetes mellitus) and vascular dementia are the most common forms of dementia. Lifestyle risk factors including obesity and type 2 diabetes increase the risk for the development of both vascular and nonvascular dementia in later life. Previous literature reported that people with diabetes mellitus had 70% greater risk for dementia development.Traditionally, type-2 diabetes and AD (type-3 diabetes) have been thought as independent disorders; recent literature suggests possible links that could lead to common effective modalities of treatment. Furthermore, the highly innervated pancreas shares many features with the brain at molecular levels.Metformin is recommended as the first line for the treatment of patients with type 2 diabetes mellitus due to its effectiveness, favorable effects on lipids and cardiovascular risks, and safety profile.The previous restriction of the use of metformin in patients with the moderate renal disease is loosened by the Food and Drug Organization(5,6). Thus the use of this valuable and affordable drug is expected to increase.The American Diabetes Association recommended the periodic measurement of vitamin B12 and supplementation as needed to reflect the recent evidence showing the association of long-term use of metformin and B12 deficiency.Although the role of vitamin B12 deficiency in the development of dementia is well-established, the role of metformin in B12 deficiency and dementia remain to be elucidated.Insulin resistance is considered as a primary factor for the association of diabetes mellitus and dementia. However, the role of insulin sensitizer in the prevention of dementia remains unclear.Furthermore, there is an increasing concern about the role of metformin in cognitive disorders.Thus we conducted this narrative review, in this study we reviewed the literature to assess the interaction of Alzheimer's disease, the gut, and its microbiome, and to assess the role of metformin and other drugs used for type 1&2 diabetes mellitus as possible therapies for the AD. The role of microbiota and fecal transplantation on cognitive disorders was also discussed.…

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Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Literature Review from the year 2020 in the subject Medicine - Other, University of Tabuk (Medical College, University of Tabuk, Saudi Arabia), language: English, abstract: The current books highlights the importance of diet and exercise on diabetes mellitus, it also touched the effects of morningness-evenenigness on the development and glycemic control of diabetes. In addition, the book discussed the concept of chrononutrition (meal timing, contents, and composition), its impacts on diabetes, body weight, and psychiatric disorders including depression. A broader insight towards meal and exercise timing, relationship between daylight, psychiatric disorders, body weight, and diabetes. The book included a section regarding diabetes prevention programs.…

Taschenbuch. Condición: Neu. Druck auf Anfrage Neuware - Printed after ordering - Master's Thesis from the year 2017 in the subject Medicine - General, grade: C, , language: English, abstract: The aim of the work is to assess the level of Retinol Binding Protein 4 in type 2 diabetic patients with and without liver cirrhosis. Diabetes mellitus is a common disease despite the fact that only half or two thirds are diagnosed, the figure is around 189 million people in 2003, and this may reach 324 million by 2025. Diabetes mellitus result from a lack or diminished effectiveness of endogenous insulin. Hyperglycemia is just one aspect of a far reaching metabolic derangement, which may cause serious microvascular and macrovascular complications. Etiological wise diabetes mellitus is classified into type 1, type 2 and other causes, with type 2 accounting for 90% of cases globally. The prevalence of type 2 diabetes continues to rise at alarming rate, significant defect in glucose homeostasis and fuel metabolism are detectable long before overt diabetes occurs. One of the earliest derangements in metabolism is insulin resistance. It is defined as impaired glucose disposal in a hyperinsulinemic -euglycemic study. Fasting hyperinsulinemia, a compensatory mechanism to maintain euglycemia in setting of insulin resistance, is also present before overt diabetes occurs. Integrated fuel homeostasis relies among interactions among numerous tissues in widely varying states, including the fed state, fasting, and exercise. This harmony in various tissues is maintained by communication between them, and is signaled by glucose and its various metabolites. When this communication between tissues (mainly pancreas, adipose tissues, and liver) is lost insulin resistance and diabetes mellitus occurs. Retinol binding protein 4 (RBP4) a 21-KDa protein synthesized in the liver and adipose tissues, formerly recognized for its role as a specific transport for vitamin A, now it is known that it plays a crucial role in insulin resistance and diabetes mellitus. Adipose RBP4 expression and serum RBP4 level are elevated in mouse model of insulin resistance, elevated circulating RBP4 increase blood glucose by inhibiting insulin signaling in skeletal muscle and upregulating hepatic gluconeogenesis.…

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Condición: Sehr gut. Zustand: Sehr gut | Sprache: Englisch | Produktart: Bücher | Literature Review from the year 2017 in the subject Medicine - Internal Medicine, grade: C, , language: English, abstract: Dementia is a multifaceted syndrome with a significant public health, social, and economic burden; there are forty-four million people affected by the disease worldwide according to the most recent estimate.The number is projected to double by the year 2030 and to triple by 2050. Alzheimer's disease (AD, or type-3 diabetes mellitus) and vascular dementia are the most common forms of dementia. Lifestyle risk factors including obesity and type 2 diabetes increase the risk for the development of both vascular and nonvascular dementia in later life. Previous literature reported that people with diabetes mellitus had 70% greater risk for dementia development.Traditionally, type-2 diabetes and AD (type-3 diabetes) have been thought as independent disorders; recent literature suggests possible links that could lead to common effective modalities of treatment. Furthermore, the highly innervated pancreas shares many features with the brain at molecular levels. Metformin is recommended as the first line for the treatment of patients with type 2 diabetes mellitus due to its effectiveness, favorable effects on lipids and cardiovascular risks, and safety profile.The previous restriction of the use of metformin in patients with the moderate renal disease is loosened by the Food and Drug Organization(5,6). Thus the use of this valuable and affordable drug is expected to increase. The American Diabetes Association recommended the periodic measurement of vitamin B12 and supplementation as needed to reflect the recent evidence showing the association of long-term use of metformin and B12 deficiency.Although the role of vitamin B12 deficiency in the development of dementia is well-established, the role of metformin in B12 deficiency and dementia remain to be elucidated. Insulin resistance is considered as a primary factor for the association of diabetes mellitus and dementia. However, the role of insulin sensitizer in the prevention of dementia remains unclear.Furthermore, there is an increasing concern about the role of metformin in cognitive disorders.Thus we conducted this narrative review, in this study we reviewed the literature to assess the interaction of Alzheimer's disease, the gut, and its microbiome, and to assess the role of metformin and other drugs used for type 1&2 diabetes mellitus as possible therapies for the AD. The role of microbiota and fecal transplantation on cognitive disorders was also discussed.…

PAP. Condición: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Literature Review from the year 2017 in the subject Medicine - Internal Medicine, grade: C, , language: English, abstract: Dementia is a multifaceted syndrome with a significant public health, social, and economic burden; there are forty-four million people affected by the disease worldwide according to the most recent estimate.The number is projected to double by the year 2030 and to triple by 2050.Alzheimer's disease (AD, or type-3 diabetes mellitus) and vascular dementia are the most common forms of dementia. Lifestyle risk factors including obesity and type 2 diabetes increase the risk for the development of both vascular and nonvascular dementia in later life. Previous literature reported that people with diabetes mellitus had 70% greater risk for dementia development.Traditionally, type-2 diabetes and AD (type-3 diabetes) have been thought as independent disorders; recent literature suggests possible links that could lead to common effective modalities of treatment. Furthermore, the highly innervated pancreas shares many features with the brain at molecular levels.Metformin is recommended as the first line for the treatment of patients with type 2 diabetes mellitus due to its effectiveness, favorable effects on lipids and cardiovascular risks, and safety profile.The previous restriction of the use of metformin in patients with the moderate renal disease is loosened by the Food and Drug Organization(5,6). Thus the use of this valuable and affordable drug is expected to increase.The American Diabetes Association recommended the periodic measurement of vitamin B12 and supplementation as needed to reflect the recent evidence showing the association of long-term use of metformin and B12 deficiency.Although the role of vitamin B12 deficiency in the development of dementia is well-established, the role of metformin in B12 deficiency and dementia remain to be elucidated.Insulin resistance is considered as a primary factor for the association of diabetes mellitus and dementia. However, the role of insulin sensitizer in the prevention of dementia remains unclear.Furthermore, there is an increasing concern about the role of metformin in cognitive disorders.Thus we conducted this narrative review, in this study we reviewed the literature to assess the interaction of Alzheimer's disease, the gut, and its microbiome, and to assess the role of metformin and other drugs used for type 1&2 diabetes mellitus as possible therapies for the AD. The role of microbiota and fecal transplantation on cognitive disorders was also discussed. 64 pp. Englisch. …

PAP. Condición: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Shipped from UK. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

PAP. Condición: New. New Book. Delivered from our UK warehouse in 4 to 14 business days. THIS BOOK IS PRINTED ON DEMAND. Established seller since 2000.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Literature Review from the year 2020 in the subject Medicine - Other, University of Tabuk (Medical College, University of Tabuk, Saudi Arabia), language: English, abstract: The current books highlights the importance of diet and exercise on diabetes mellitus, it also touched the effects of morningness-evenenigness on the development and glycemic control of diabetes. In addition, the book discussed the concept of chrononutrition (meal timing, contents, and composition), its impacts on diabetes, body weight, and psychiatric disorders including depression. A broader insight towards meal and exercise timing, relationship between daylight, psychiatric disorders, body weight, and diabetes. The book included a section regarding diabetes prevention programs. 72 pp. Englisch.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Several studies addressed the parental education direct effects on the academic performance of the children in Western countries; however, in the Middle East Countries, only a few studies reported this issue. The current study aimed to address the reciprocity of the parental education and academic performance of their children's in the medical college of University of Tabuk, Kingdom of Saudi Arabia.…