Isbn: 9786206144168 - titanium dioxide: quercetin combinational drug’s role in skin cancer (3 resultados)

Taschenbuch. Condición: Neu. Titanium Dioxide | Quercetin Combinational Drug's Role in Skin [.] | Madhava C. Reddy (u. a.) | Taschenbuch | Großformatiges Paperback. Klappenbroschur | Englisch | LAP Lambert Academic Publishing | EAN 9786206144168 | Verantwortliche Person für die EU: SIA OmniScriptum Publishing, Brivibas Gatve 197, 1039 RIGA, LETTLAND, customerservice[at]vdm-vsg[dot]de | Anbieter: preigu.…

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Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - This book describes the role of titanium dioxide nanotubes conjugated with quercetin in skin cancer and inflammation. TNT-Quercetin are human safe, cost effective and stable chemical with numerous biomedical applications. The authors of this book developed a novel drug combinational molecule by conjugating TNT with quercetin. The authors found the enhanced anti-cancer activity of TNT-Qu by inducing apoptosis and cell cycle arrest at the G2/M phase in B16F10 cells. Furthermore, TNT-Qu treatment up-regulated cleaved caspase-3 expression in B16F10 cells. More importantly, the in-vivo data demonstrated that TNT-Qu treatment inhibited the growth and metastasis of skin tumors significantly by down-regulating the pSTAT3 expression and restoring Gammad T cell population when compared to TNT or quercetin alone treatment. Taken together, the in-vitro and in-vivo data strongly suggest that TNT-Qu could be a novel combinational therapeutic agent for the treatment of skin cancer.…