Isbn: 9786203193589 - natural compounds modulate an arsenal of ncrnas in breast cancer: lncrna-h19/mir-486-5p/mir-17-5p: a novel circuit sensitive breast cancer cells to immune eradication (5 resultados)

Taschenbuch. Condición: Neu. Natural Compounds Modulate an Arsenal of ncRNAs in Breast Cancer | lncRNA-H19/miR-486-5p/miR-17-5p: A novel circuit sensitive Breast cancer cells to immune eradication | Aisha ElKhouly (u. a.) | Taschenbuch | Englisch | 2020 | LAP LAMBERT Academic Publishing | EAN 9786203193589 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Triple Negative Breast Cancer (TNBC) is believed to be an immunogenic tumor, therefore; immunotherapy has arisen to be a promising approach for TNBC treatment. Immune escape can be caused by the inactivation of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). NKs and CTLs express an array of activating receptors on their surface that bind to unique activating ligands exclusively present on cancer cells such as MICA, MICB and CD155. Unfortunately, the expression of these immune ligands is decreased by malignant cells through their shedding down. Interestingly, non-coding RNAs (ncRNAs) can regulate the surface expression of the activating ligands on cancer cells directly and indirectly. Some plant products were known as modulators of ncRNAs expression in a variety of cancers. Vitexin, is a flavone C-glycoside which impairs the viability and induces the apoptosis in some cancer cells. Our ultimate goal was to investigate the impact of ncRNAs in up-streaming MICA, MICB and CD155 expression levels in TNBC cells. Moreover; investigating the effect of the 3'-O-acetylvitexin derivative which is a more potent form of Vitexin on ncRNAs and the activating ligands expression. 144 pp. Englisch.…

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Triple Negative Breast Cancer (TNBC) is believed to be an immunogenic tumor, therefore; immunotherapy has arisen to be a promising approach for TNBC treatment. Immune escape can be caused by the inactivation of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). NKs and CTLs express an array of activating receptors on their surface that bind to unique activating ligands exclusively present on cancer cells such as MICA, MICB and CD155. Unfortunately, the expression of these immune ligands is decreased by malignant cells through their shedding down. Interestingly, non-coding RNAs (ncRNAs) can regulate the surface expression of the activating ligands on cancer cells directly and indirectly. Some plant products were known as modulators of ncRNAs expression in a variety of cancers. Vitexin, is a flavone C-glycoside which impairs the viability and induces the apoptosis in some cancer cells. Our ultimate goal was to investigate the impact of ncRNAs in up-streaming MICA, MICB and CD155 expression levels in TNBC cells. Moreover; investigating the effect of the 3'-O-acetylvitexin derivative which is a more potent form of Vitexin on ncRNAs and the activating ligands expression.…

Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: ElKhouly AishaAisha ElKhouly works as a medical educator in a multinational company. In 2018, Aisha was graduated from the Faculty of pharmacy and biotechnology , GUC with Excellence with high honors . In 2020, she accomplished he.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Triple Negative Breast Cancer (TNBC) is believed to be an immunogenic tumor, therefore; immunotherapy has arisen to be a promising approach for TNBC treatment. Immune escape can be caused by the inactivation of natural killer (NK) cells and cytotoxic T lymphocytes (CTLs). NKs and CTLs express an array of activating receptors on their surface that bind to unique activating ligands exclusively present on cancer cells such as MICA, MICB and CD155. Unfortunately, the expression of these immune ligands is decreased by malignant cells through their shedding down. Interestingly, non-coding RNAs (ncRNAs) can regulate the surface expression of the activating ligands on cancer cells directly and indirectly. Some plant products were known as modulators of ncRNAs expression in a variety of cancers. Vitexin, is a flavone C-glycoside which impairs the viability and induces the apoptosis in some cancer cells. Our ultimate goal was to investigate the impact of ncRNAs in up-streaming MICA, MICB and CD155 expression levels in TNBC cells. Moreover; investigating the effect of the 3'-O-acetylvitexin derivative which is a more potent form of Vitexin on ncRNAs and the activating ligands expression.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 144 pp. Englisch.…