9783843353311 - micrornas in osteosarcomas: expression analysis and potential role in tumour progression de montanini, luisa (5 resultados)
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Taschenbuch. Condición: Neu. MicroRNAs in osteosarcomas | Expression analysis and potential role in tumour progression | Luisa Montanini | Taschenbuch | 116 S. | Englisch | 2011 | LAP LAMBERT Academic Publishing | EAN 9783843353311 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrüc…k, mail[at]preigu[dot]de | Anbieter: preigu.
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In many studies, performed to investigate the genes and gene products that drive the metastatic process, it has become evident that, in addition to alterations in protein-encoding genes, abnormalities in non-coding genes can also co…ntribute to cancer pathogenesis. In the context of microRNAs in tumours, our aim was to evaluate whether pro- metastatic and non-metastatic sarcoma cells may differ in their microRNA expression, in the effort to identify single pro-metastatic microRNAs in bone and soft-tissue sarcomas. A number of microRNAs reported in the miRNA registry data base were found to be differential expressed in MG-63 and 143B osteosarcoma model cell lines. Two of the differentially expressed microRNA, miR-93 and miR- 210, for which no functional data were available, were analyzed in different cell lines and tissues and investigated for their potential involvement in motility phenomena. The expression of another set of four differentially expressed miRNAs (miR-9, miR- 183, miR-196a, miR-484), was identified through a global expression analysis, and analyzed in surgical specimens of low- and high-grade osteosarcoma patients. 116 pp. Englisch.
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Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Montanini LuisaLuisa Montanini is a biologist specialized in Medical Genetics at the University of Milan. She get her PhD in Systemic Physiopathology at the University of Parma in 2009. Her main researc…h interest is the understanding.
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Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In many studies, performed to investigate the genes and gene products that drive the metastatic process, it has become evident that, in addition to alterations in protein-encoding genes, abnormalities in non-coding genes can also contri…bute to cancer pathogenesis. In the context of microRNAs in tumours, our aim was to evaluate whether pro- metastatic and non-metastatic sarcoma cells may differ in their microRNA expression, in the effort to identify single pro-metastatic microRNAs in bone and soft-tissue sarcomas. A number of microRNAs reported in the miRNA registry data base were found to be differential expressed in MG-63 and 143B osteosarcoma model cell lines. Two of the differentially expressed microRNA, miR-93 and miR- 210, for which no functional data were available, were analyzed in different cell lines and tissues and investigated for their potential involvement in motility phenomena. The expression of another set of four differentially expressed miRNAs (miR-9, miR- 183, miR-196a, miR-484), was identified through a global expression analysis, and analyzed in surgical specimens of low- and high-grade osteosarcoma patients.VDM Verlag, Dudweiler Landstraße 99, 66123 Saarbrücken 116 pp. Englisch.
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Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - In many studies, performed to investigate the genes and gene products that drive the metastatic process, it has become evident that, in addition to alterations in protein-encoding genes, abnormalities in non-coding genes can also contrib…ute to cancer pathogenesis. In the context of microRNAs in tumours, our aim was to evaluate whether pro- metastatic and non-metastatic sarcoma cells may differ in their microRNA expression, in the effort to identify single pro-metastatic microRNAs in bone and soft-tissue sarcomas. A number of microRNAs reported in the miRNA registry data base were found to be differential expressed in MG-63 and 143B osteosarcoma model cell lines. Two of the differentially expressed microRNA, miR-93 and miR- 210, for which no functional data were available, were analyzed in different cell lines and tissues and investigated for their potential involvement in motility phenomena. The expression of another set of four differentially expressed miRNAs (miR-9, miR- 183, miR-196a, miR-484), was identified through a global expression analysis, and analyzed in surgical specimens of low- and high-grade osteosarcoma patients.
