ISBN: 9783659277016 - homology modeling of dopamine receptors and docking study: structure based drug design (4 resultados)

Taschenbuch. Condición: Neu. Homology Modeling of Dopamine Receptors and Docking Study | Structure Based Drug Design | Manish K. Gupta (u. a.) | Taschenbuch | Englisch | LAP Lambert Academic Publishing | EAN 9783659277016 | Verantwortliche Person für die EU: preigu GmbH & Co. KG, Lengericher Landstr. 19, 49078 Osnabrück, mail[at]preigu[dot]de | Anbieter: preigu.…

Paperback. Condición: Like New. LIKE NEW. SHIPS FROM MULTIPLE LOCATIONS. book.

Taschenbuch. Condición: Neu. nach der Bestellung gedruckt Neuware - Printed after ordering - Dopamine receptors (DRs) belong to the class A of G-protein coupled receptors (GPCRs) super family. The five subtypes of dopamine receptors (DRs) i.e. D1R, D2R, D3R, D4R and D5R have been characterized and classified in D1-like (D1R and D5R; stimulatory) and D2-like (D2R, D3R, and D4R; inhibitory) subfamilies based on their sequence similarities and physiological response. The DRs are involved in many physiological processes and thus, deregulation in their activity led to the various mental disorders. Therefore, the DRs are attractive targets for the development of new drug molecules for the treatment of various CNS disorders. This book describes the development and validation of 3D structure model for all DR isoforms. The 3D structure model of DRs may be used in docking study to identify crucial amino acid residues involved Drug-Receptor interactions. This is turn, will contribute in the designing of novel DR agonists and antagonists. This is also helpful to understand the mechanism of activation and inhibition of these receptors. Also, the docking models will be useful In Silico activity prediction of new compounds as well as in virtual screening to identify new lead molecules.…

Kartoniert / Broschiert. Condición: New. Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Gupta Manish K.Manish K. Gupta (M. Pharm., Ph.D.) is working as an associate professor at Dept. of Pharma. Chemistry, ISF College of Pharmacy, Moga, India. His research interests include ligand and structure based drug design, high d. …