springer us jan 2001 (77 resultados)

Buch. Condición: Neu. Neuware - Lo, soul! seest thou not God's purpose from the first The earth to be spann'd, connected by net-work From Passage to India! Walt Whitman, 'Leaves of Grass', 1900. The Internet is growing at a tremendous rate today. New services, such as telephony and multimedia, are being added to the pure data-delivery framework of yesterday. Such high demands on capacity could lead to a 'bandwidth-crunch' at the core wide-area network resulting in degra dation of service quality. Fortunately, technological innovations have emerged which can provide relief to the end-user to overcome the In ternet's well-known delay and bandwidth limitations. At the physical layer, a major overhaul of existing networks has been envisaged from electronic media (such as twisted-pair and cable) to optical fibers - in the wide area, in the metropolitan area, and even in the local area set tings. In order to exploit the immense bandwidth potential of the optical fiber, interesting multiplexing techniques have been developed over the years. Wavelength division multiplexing (WDM) is such a promising tech nique in which multiple channels are operated along a single fiber si multaneously, each on a different wavelength. These channels can be independently modulated to accommodate dissimilar bit rates and data formats, if so desired. Thus, WDM carves up the huge bandwidth of an optical fiber into channels whose bandwidths (1-10 Gbps) are compati ble with peak electronic processing speed.

Buch. Condición: Neu. Neuware - This book should be of interest to scholars, researchers, students, and practitioners alike. Scholars, researchers, and students of personal relationship development will recognize in this book the first serious attempt in over 40 years to do a large-scale, longitudinal study of premarital factors that predict premarital breakup and marital quality; they should also appreciate our attempt to develop a theoretical rationale for predicted paths and to test those paths with the best available statistical tools. Practitioners-while generally not as interested in the intricacies of the statistical results-will find much that is useful to them as they help individuals and couples make decisions about their intimate relationships, their readiness for marriage, and how to increase the probability for marital success. Teachers, family life educators, premarital counselors, and clergy will find helpful our 'principles for practice,' particularly as described in Chapter 9, as they teach and counsel couples in any premarital situation. My interest in the development of relationships from premarital to marital probably began when I got married in 1972 and started to notice all of the characteristics my wife and I brought from our respective families and how our 'new beginning' as a married couple was in many ways the continuation of our premarital relationship, only more refined and more intense. My professional interest began when I did my doctoral dissertation in 198 1 on premarital predictors of early marital satisfaction (the results of that study are reported in Chapter 8).

Buch. Condición: Neu. Neuware - Biophysical studies in the 1950ies and 1960ies led to the realization that the water permeability of certain biological membranes must be due to the presence of water transporting proteins. This hypothesis was confirmed in 1991 and 1992 with the pioneering discovery of the first molecular membrane water channel, CHIP28, by Agre and coworkers. This integral membrane protein, which is abundant in the erythrocyte membrane and in many epithelial cells, is now called aquaporin-1 or AQP1. Thus the terms water channel or aquaporin are synonymous. In July 2000 more than 200 researchers came together in Gothenburg, Sweden, for the `3rd International Conference on the Molecular Biology and Physiology of Water and Solute Transport' to discuss progress in this emerging research field. 58 different presentations from this conference are the basis for this book. Cumulatively, these 58 short chapters provide a balanced overview complementing numerous recent reviews in this field.

Buch. Condición: Neu. Neuware - The triennial International Alloy Conferences (lACs) aim at the identification and promotion of the common elements developed in the study, either experimental, phenomenological, or theoretical and computational, of materials properties across materials types, from metals to minerals. To accomplish this goal, the lACs bring together scientists from a wide spectrum of materials science including experiment, theory, modeling, and computation, incorporating a broad range of materials properties. The first lAC, lAC-I, took place in Athens, Greece, June 16-21, 1996. The present volume of proceedings contains the papers presented at IAC-2, that took place in Davos, Switzerland, August 8-13, 1999. The topics in this book fall into several themes, which suggest a number of different classification schemes. We have chosen a scheme that classifies the papers in the volume into the categories Microstructural Properties; Ordering, Kinetics and Diffusion; Magnetic Properties and Elastic Properties. We have juxtaposed apparently disparate of revealing the dynamic character approaches to similar physical processes, in the hope of the processes under consideration. We hope this will invigorate new kinds of discussion and reveal challenges and new avenues to the description and prediction of properties of materials in the solid state and the conditions that produce them.

Buch. Condición: Neu. Neuware - The design of computer systems to be embedded in critical real-time applications is a complex task. Such systems must not only guarantee to meet hard real-time deadlines imposed by their physical environment, they must guarantee to do so dependably, despite both physical faults (in hardware) and design faults (in hardware or software). A fault-tolerance approach is mandatory for these guarantees to be commensurate with the safety and reliability requirements of many life- and mission-critical applications. This book explains the motivations and the results of a collaborative project', whose objective was to significantly decrease the lifecycle costs of such fault tolerant systems. The end-user companies participating in this project already deploy fault-tolerant systems in critical railway, space and nuclear-propulsion applications. However, these are proprietary systems whose architectures have been tailored to meet domain-specific requirements. This has led to very costly, inflexible, and often hardware-intensive solutions that, by the time they are developed, validated and certified for use in the field, can already be out-of-date in terms of their underlying hardware and software technology.

Buch. Condición: Neu. Neuware - Future Directions in Postal Reform brings together leading practitioners, world-wide postal administrations, and the courier industry, as well as a number of regulators, academic economists, mailers, and lawyers, to examine some of the major policy and regulatory issues facing the postal and delivery industry. Issues addressed include international postal policy; the universal service obligation; regulation; competition, entry, and the role of scale and scope economies; the nature and role of cost analysis in postal service; productivity; interaction of law and economics; and future technologies and service standards.

Buch. Condición: Neu. Neuware - It is an authentic privilege to have the opportunity to assemble and edit a new volume on 'Prolactin,' the first in several decades to be devoted to this fascinating hormone in all its aspects. The obvious clinical rationale for understanding prolactin (PRL) is the frequent occurrence of prolactinomas, the most common type of pituitary tumor. Fortunately, medical management of prolactinomas can be based on our under standing of the physiology of hypothalamic control of the lactotroph. Armed with this knowledge, therapies for proiactinomas are highly successful and well tolerated. Be cause of the historical and practical importance of knowledge regarding the hypothala mus-Iactotroph axis, the first chapters of this volume are dedicated to reviewing the physiology, development, and cell biology of lactotroph regulation. Chapters focusing on prolactinomas and related clinical issues follow these. PRL is the primary hormone that is responsible for 'parental care' in many verte brate species. This reproductive strategy is not unique to mammals, but it has devel oped through evolution to be the central distinguishing feature of the mammalian life cycle. Among the mammals, mice have become the most effective research species in recent years. This can be traced to the development of a wide range of methods for manipulating mouse genetics, and thereby influencing development, physiology and behavior. Mice also provide a profound illustration of the physiological challenges faced in maternity. Female mice undergo a post-partum estrous, and often are both pregnant and lactating simultaneously.

Buch. Condición: Neu. Neuware - Mitochondria from mammalian tissues possess an elaborate system for 2+ 2+ transporting Ca across their inner membrane which consists of Ca import, 2+ via the Ca uniporter, in response to the mitochondrial membrane 2+ + potential and of Ca release by an antiport system in exchange for H + 9,23 or Na (see Fig. l) . Because the uniporter is dependent upon the external 2+ 2+ 2+ 2+ Ca concentration ([Ca ]), mitochondria accumulate Ca until the [Ca ] o o 2+ decreases to the level at which the uniporter activity balances the Ca efflux. 2+ The [Ca ] at which the uniporter and efflux activities are equal is defined o the 'setpoint' andcorresponds to values between 0.3-3µM. 2+ Figure 1. The Ca transport system of the inner membrane of mammalian mitochondria. U, + 2+ + + uniporter. I, Na -independent efflux mechanism or Ca /2H exchanger. D, Na -dependent 2+ + efflux mechanism or Ca /2Na exchanger. PTP, permeability transition pore. FP, 11 flavoprotein. membrane potential. pH gradient. Adapted from .

Buch. Condición: Neu. Neuware - The use of mathematical modeling te chniques in biomedical research is playing an increasingly important role aso ne seeks tounderstand the physiopathology of disease processes. This includes not only understand ing mechanisms ofphysiological processes, but diagnosis and treatment. In addition, its introduction in the study of genomics andproteomics is key in understanding the functional ch aracteristics of gene expression and protein assembly and secretion. Finally, with the increasing com plexity and associated cost of drug development, modeling techniques are being used to streamline the process. We have workedin c lose collaboration with colleagues in biomedical and pharmaceutical research for a number of years applying and refining mathematical modeling techniques to avariety o f problems. In addition, we haveworked incollaboration with colleagues in applied m athematics and statistics to develop new algorithms to solve new setsof problems as theyemerge ino ur research efforts. Finally, we have worked with colleagues in computer sciencet o develop new software tools that bring the power of mathematical modeling to a broad research community. This books brings together mucho f what we have learned over the years, and presents the material in a format that should be accessible both to the novice reader and those desiring more detailed information about specific techniques.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In this book, academic researchers and technologists will find important information on the interaction of polymeric and non-polymeric inhibitors with a variety of scale forming crystals such as calcium phosphates, calcium carbonate, calcium oxalates, barium sulfate, calcium pyrophosphates, and calcium phosphonates. Moreover, the book delivers information to plant managers and formulators who would like to broaden and deepen their knowledge about processes involved in precipitation of sparingly soluble salts and learn more about the inhibitory aspects of various commercially available materials. Furthermore, experienced researchers will obtain fruitful and inspiring ideas from the easily accessible information about overlapping research areas, which will promote discoveries of new inhibitors (synthetic and/or natural) for the currently unmet challenges. 292 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Residential Exposure Assessment: A Source Book is the result of a multiyear effort known as the Residential Exposure Assessment Project (REAP) which was initiated by the Society for Risk Analysis and the International Society of Exposure Analysis. This textbook is the primary product of the REAP and it contains contributions from over 30 professionals from a variety of disciplines such as chemistry, biology, physics, engi neering, industrial hygiene, toxicology, pharmacology, and environmental law, reflecting the diverse knowledge and resources necessary to assess and manage potential exposures occurring in and around the home. Expert working groups were organized for each of the 13 chapters to address such issues as U. S. legislation relevant to products used in and around the residence, methods for measuring and modeling exposures across multiple pathways and routes, and distributional data available for key residential exposure factors. This volume is a compendium of information about predictive methods and tools, monitoring methods, data sources, and key variables that characterize exposures in the residential setting. It presents approaches for doing exposure assessments in and around all types of residences. The purpose of the Source Book is to provide a resource for use in educational programs and for 'practitioners' of residential exposure assessment. Accordingly, this book is intended for risk assessors, exposure assessors, students, initi ates new to the concept of risk assessment, industrial hygienists assessing health hazards in the home, engineers, and monitoring specialists. 420 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In March 1999, New York University Salomon Center in assocIatIOn with the Department of Finance at NYU Stern held a one-day conference on the impact of real estate cycles on the real estate industry both from a domestic as well as an international perspective. The conference featured the leading research on this topic in the United States, Europe and Asia. Currendy, the real estate industry is at a critical point. New development projects around the world are being put on hold given recent developments in the international capital markets. The industry is hard hit by the decline in real estate investment trust (REIT) share prices and a shrink ing pool of capital for real estate ventures. This has unfortunately coincided with serious financial problems of very large hedge funds and other institutional investors in the market for commercial mortgage backed securities. There is need for new insights into the implications of U. S. and global real estate cycles on real estate secu rities including REITs and mortgage-backed securities as well as direct real estate investment. This global orientation is important given the high mobility of capital into the real estate, the increasing integration of real estate markets, and the proposed expan sion of real estate investment trusts (REIT) into international real estate. The process of globalization has resulted in increased competition between cities for the attrac tion of investment. 140 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The aim of Language for those who have Nothing is to think psychiatry through the writings of Mikhail Bakhtin. Using the concepts of Dialogism and Polyphony, the Carnival and the Chronotope, a novel means of navigating the clinical landscape is developed. Bakhtin offers language as a social phenomenon and one that is fully embodied. Utterances are shown to be alive and enfleshed and their meanings realised in the context of given social dimensions. The organisation of this book corresponds with carnival practices of taking the high down to the low before replenishing its meaning anew. Thus early discussions of official language and the chronotope become exposed to descending levels of analysis and emphasis. Patients and practitioners are shown to occupy an entirely different spatio-temporal topography. These chronotopes have powerful borders and it is necessary to use the Carnival powers of cunning and deception in order to enter and to leave them. The book provides an overview of practitioners who have attempted such transgression and the author records his own unnerving experience as a pseudopatient. By exploring the context of psychiatry's unofficial voices: its terminology, jokes, parodies, and everyday narratives, the clinical landscape is shown to rely heavily on unofficial dialogues in order to safeguard an official identity. 264 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume brings together contributions from an experienced group of archaeologists and geologists whose common objective is to present thorough and current reviews of the diverse ways in which methods from the earth sciences can contribute to archaeological research. Many areas of research are addressed here, including artifact analysis and sourcing, landscape reconstruction and site formation analysis, soil micromorphology and geophysical exploration of buried sites. 536 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Because of their mutually influencing interactions, information systems and modern manufacturing systems are intertwined. They have been so integrated that information systems have become an embedded and critical component of any effective manufacturing system. The impact of the increasing focus on information permeates throughout the manufacturing life cycle, from product conceptualization, design, process planning, all the way to production, order fulfilment, and customer services. For these reasons, it is critical that we study information-based manufacturing in its entirety, crossing the traditional functional boundaries and building as much synergy between Information Systems (IS), Information Technology (IT), and manufacturing as possible. This is the motivation for this book and, to this end, the purpose of this book is threefold: to establish an up-to-date interdisciplinary research framework for information-based manufacturing that builds on the research foundation from IS and IT and manufacturing research; to develop a forward-looking research agenda for information-based manufacturing for identifying future directions for research and applications; and to foster a joint academic and industrial research agenda in information systems and manufacturing by identifying the greatest synergy possible between academic research and industrial practices. 354 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Drawing data from a classic region for Paleolithic research in Europe, this book explores how early modern humans obtained lithic raw materials and analyzes the different utilization patterns for locally available materials compared with those from a greater distance. The author locates these patterns within an ecological context and argues that early modern humans selected specific mobility strategies to accommodate changes in subsistence environments. 236 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In his earlier work the author has studied stress and the personality characteristics that protect us from its effects on health and well-being. In this new book he places humor firmly within the literatures of coping processes, the moderation of stressful experiences, and health by showing how humor can help create and encourage feelings of community, closeness, and control. Lefcourt blends empirical research with anecdotal reports in this thoughtful volume. 212 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes termed Electron Spin Resonance spectroscopy - has manifold potential uses in biochemistry and medicine. The paramount importance of EPR spectroscopy applied to biological tissues and fluids is that it identifies the changes in redox processes that contribute to disease. EPR spectroscopy has come a long way from its original use to detect malignant tumors. For example, the development and later refinement of methods of low-temperature registration of biological tissues widened the scope of EPR spectroscopy. Innovations made possible by the introduction of spin labels, probes, and traps made EPR spectroscopy ever more applicable to biochemistry and medicine, to the point where in vivo studies are being carefully considered. This comprehensive book discusses spectra of many tissues and bodily fluids, and the quantitative nature of paramagnetic centers in both normal individuals and patients suffering from a variety of diseases. Special attention is given to the EPR examination of bio-molecules, such as enzymes, polypeptides, vitamins, lipids, hydrocarbons, etc., which play an essential role in human activity. This book will be of great interest to physicians specializing in many different areas. Similarly, biologists, biochemists, biophysicists, and chemists will find this book very useful. It has also been written so that it may be used as a textbook at graduate level. 292 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The primary audience for this book are advanced undergraduate students and graduate students. Computer architecture, as it happened in other fields such as electronics, evolved from the small to the large, that is, it left the realm of low-level hardware constructs, and gained new dimensions, as distributed systems became the keyword for system implementation. As such, the system architect, today, assembles pieces of hardware that are at least as large as a computer or a network router or a LAN hub, and assigns pieces of software that are self-contained, such as client or server programs, Java applets or pro tocol modules, to those hardware components. The freedom she/he now has, is tremendously challenging. The problems alas, have increased too. What was before mastered and tested carefully before a fully-fledged mainframe or a closely-coupled computer cluster came out on the market, is today left to the responsibility of computer engineers and scientists invested in the role of system architects, who fulfil this role on behalf of software vendors and in tegrators, add-value system developers, R&D institutes, and final users. As system complexity, size and diversity grow, so increases the probability of in consistency, unreliability, non responsiveness and insecurity, not to mention the management overhead. What System Architects Need to Know The insight such an architect must have includes but goes well beyond, the functional properties of distributed systems. 650 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We have considered it to be a demanding assignment to provide a complete exposition dealing with the nature of radiation, its effects, and protection against it to workers in health-related activities. 'Radiation' (and more precisely 'ionizing radiation') is emitted by X-ray machines, nuclear reactors, and nuclear weapons, but also comes from natural sources to which we are all exposed. It would have been easier to deal with this subject area with the terminology and mathematics employed by specialists. However, although most of the potential readers probably have obtained further pertinent knowledge, we assume no more than a high school education in science and mathematics and the challenge was to provide maximum information within this constraint. This book contains five sections: (A) Radiation Physics, (B) Radiological Physics, (C) Radiation Biology, (D) Radiation Effects on Human Populations, and (E) Radiation Protection. Each section is preceded by a synopsis covering its essential features. It provides sufficient information to enable readers to obtain a general under standing of the subject of the section and an adequate background for comprehension of other sections. The more detailed presentation in the bulk of each section is followed by appendixes that generally contain more advanced topics. This scheme necessarily involves some repetition but permits a more flexible approach for readers who are especially interested in the contents of particular sections. 236 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Content-Based Audio Classification and Retrieval for Audiovisual Data Parsing is an up-to-date overview of audio and video content analysis. Included is extensive treatment of audiovisual data segmentation, indexing and retrieval based on multimodal media content analysis, and content-based management of audio data. In addition to the commonly studied audio types such as speech and music, the authors have included hybrid types of sounds that contain more than one kind of audio component such as speech or environmental sound with music in the background. Emphasis is also placed on semantic-level identification and classification of environmental sounds. The authors introduce a new generic audio retrieval system on top of the audio archiving schemes. Both theoretical analysis and implementation issues are presented. The developing MPEG-7 standards are explored. Content-Based Audio Classification and Retrieval for Audiovisual Data Parsing will be especially useful to researchers and graduate level students designing and developing fully functional audiovisual systems for audio/video content parsing of multimedia streams. 164 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Because of their mutually influencing interactions, information systems and modern manufacturing systems are intertwined. They have been so integrated that information systems have become an embedded and critical component of any effective manufacturing system. The impact of the increasing focus on information permeates throughout the manufacturing life cycle, from product conceptualization, design, process planning, all the way to production, order fulfilment, and customer services. For these reasons, it is critical that we study information-based manufacturing in its entirety, crossing the traditional functional boundaries and building as much synergy between Information Systems (IS), Information Technology (IT), and manufacturing as possible. This is the motivation for this book and, to this end, the purpose of this book is threefold: to establish an up-to-date interdisciplinary research framework for information-based manufacturing that builds on the research foundation from IS and IT and manufacturing research;to develop a forward-looking research agenda for information-based manufacturing for identifying future directions for research and applications; andto foster a joint academic and industrial research agenda in information systems and manufacturing by identifying the greatest synergy possible between academic research and industrial practices.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 354 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In March 1999, New York University Salomon Center in assocIatIOn with the Department of Finance at NYU Stern held a one-day conference on the impact of real estate cycles on the real estate industry both from a domestic as well as an international perspective. The conference featured the leading research on this topic in the United States, Europe and Asia. Currendy, the real estate industry is at a critical point. New development projects around the world are being put on hold given recent developments in the international capital markets. The industry is hard hit by the decline in real estate investment trust (REIT) share prices and a shrink ing pool of capital for real estate ventures. This has unfortunately coincided with serious financial problems of very large hedge funds and other institutional investors in the market for commercial mortgage backed securities. There is need for new insights into the implications of U. S. and global real estate cycles on real estate secu rities including REITs and mortgage-backed securities as well as direct real estate investment. This global orientation is important given the high mobility of capital into the real estate, the increasing integration of real estate markets, and the proposed expan sion of real estate investment trusts (REIT) into international real estate. The process of globalization has resulted in increased competition between cities for the attrac tion of investment.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 140 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -An essential reader containing the 25 most important papers in the development of modern operating systems for computer science and software engineering. The papers illustrate the major breakthroughs in operating system technology from the 1950s to the 1990s. The editor provides an overview chapter and puts all development in perspective with chapter introductions and expository apparatus. Essential resource for graduates, professionals, and researchers in CS with an interest in operating system principles.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 612 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Residential Exposure Assessment: A Source Book is the result of a multiyear effort known as the Residential Exposure Assessment Project (REAP) which was initiated by the Society for Risk Analysis and the International Society of Exposure Analysis. This textbook is the primary product of the REAP and it contains contributions from over 30 professionals from a variety of disciplines such as chemistry, biology, physics, engi neering, industrial hygiene, toxicology, pharmacology, and environmental law, reflecting the diverse knowledge and resources necessary to assess and manage potential exposures occurring in and around the home. Expert working groups were organized for each of the 13 chapters to address such issues as U. S. legislation relevant to products used in and around the residence, methods for measuring and modeling exposures across multiple pathways and routes, and distributional data available for key residential exposure factors. This volume is a compendium of information about predictive methods and tools, monitoring methods, data sources, and key variables that characterize exposures in the residential setting. It presents approaches for doing exposure assessments in and around all types of residences. The purpose of the Source Book is to provide a resource for use in educational programs and for 'practitioners' of residential exposure assessment. Accordingly, this book is intended for risk assessors, exposure assessors, students, initi ates new to the concept of risk assessment, industrial hygienists assessing health hazards in the home, engineers, and monitoring specialists.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 420 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In his earlier work the author has studied stress and the personality characteristics that protect us from its effects on health and well-being. In this new book he places humor firmly within the literatures of coping processes, the moderation of stressful experiences, and health by showing how humor can help create and encourage feelings of community, closeness, and control. Lefcourt blends empirical research with anecdotal reports in this thoughtful volume.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 224 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The aim of Language for those who have Nothing is to think psychiatry through the writings of Mikhail Bakhtin. Using the concepts of Dialogism and Polyphony, the Carnival and the Chronotope, a novel means of navigating the clinical landscape is developed.Bakhtin offers language as a social phenomenon and one that is fully embodied. Utterances are shown to be alive and enfleshed and their meanings realised in the context of given social dimensions. The organisation of this book corresponds with carnival practices of taking the high down to the low before replenishing its meaning anew. Thus early discussions of official language and the chronotope become exposed to descending levels of analysis and emphasis.Patients and practitioners are shown to occupy an entirely different spatio-temporal topography. These chronotopes have powerful borders and it is necessary to use the Carnival powers of cunning and deception in order to enter and to leave them. The book provides an overview of practitioners who have attempted such transgression and the author records his own unnerving experience as a pseudopatient. By exploring the context of psychiatry's unofficial voices: its terminology, jokes, parodies, and everyday narratives, the clinical landscape is shown to rely heavily on unofficial dialogues in order to safeguard an official identity.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 264 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In recent years much enthusiasm and energy has been directed toward the development of human gene therapies, especially for inherited conditions and cancers. However, current gene transfer technology is limited in its transduction efficiency and ability to permanently and safely correct genomic defects. Thus the promise of gene therapy for these conditions is as yet unrealized. The progression of gene transfer technology will eventually surmount these limitations.Gene Therapy for Acute and Acquired Diseases includes selected examples of ongoing studies in molecular genetics that have the potential to evolve into human therapies for acute illnesses. These chapters are intended to highlight lesser known applications of gene therapy for acquired disorders. It is expected that human gene therapy trials for these conditions will be forthcoming in the near future, leading to previously unimaginable therapies. Thus, this first-ever book about gene therapy for acute and acquired diseases is intended to serve as a glimpse into the future.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 308 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Electron Paramagnetic Resonance (EPR) spectroscopy - also sometimes termed Electron Spin Resonance spectroscopy - has manifold potential uses in biochemistry and medicine. The paramount importance of EPR spectroscopy applied to biological tissues and fluids is that it identifies the changes in redox processes that contribute to disease.EPR spectroscopy has come a long way from its original use to detect malignant tumors. For example, the development and later refinement of methods of low-temperature registration of biological tissues widened the scope of EPR spectroscopy. Innovations made possible by the introduction of spin labels, probes, and traps made EPR spectroscopy ever more applicable to biochemistry and medicine, to the point where in vivo studies are being carefully considered.This comprehensive book discusses spectra of many tissues and bodily fluids, and the quantitative nature of paramagnetic centers in both normal individuals and patients suffering from a variety of diseases. Special attention is given to the EPR examination of bio-molecules, such as enzymes, polypeptides, vitamins, lipids, hydrocarbons, etc., which play an essential role in human activity.This book will be of great interest to physicians specializing in many different areas. Similarly, biologists, biochemists, biophysicists, and chemists will find this book very useful. It has also been written so that it may be used as a textbook at graduate level.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 292 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Earth Sciences and Archaeology brings together contributions from an experienced group of archaeologists and geologists whose common objective is to present thorough and current reviews of the diverse ways in which methods from the earth sciences can contribute to archaeological research. Many areas of research are addressed here, including artifact analysis and sourcing, landscape reconstruction and site formation analysis, soil micromorphology and geophysical exploration of buried sites.Archaeology has benefited from geological methods in many ways in recent decades. However, in the past ten to twenty years, this informal collaboration between geologists and archaeologists has grown into a formal integration of earth science and archaeology on a significant scale. This book allows the contributors to assess where we are in terms of interdisciplinary research, which approaches work best in specific situations, and where this collaborative approach should progress to in the future.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 536 pp. Englisch.