Springer springer us jan 2012 (127 resultados)

Taschenbuch. Condición: Neu. Neuware -Recent developments in various areas of chemistry have been decisively influenced by the principles of structure and mechanism and by the ideas of coordination chemistry, in particular by the donor-acceptor approach, A unified view of almost all kinds of molecular forces is provided by quantum mechanics, and for practical purposes have been classified according to model assumptions, namely, dispersion, polarization, electrostatic, and short-range forces. The latter are divided into two- and three-center covalent chemical bonds, metallic bonds, and exchange-repulsion forces. This approach allows statements of principle and systematic analysis. However, quantitative predictions on concrete large systems are virtually impossible, and there are no general rules that account for structural and chemical changes due to intermolecular interactions. Chemists are therefore left with qualitative descriptions in which the changes in electron densities are considered. Such models as the MO theory or the resonance concept unrealistically assume that the nuclei remain in fixed positions. Further difficulties are encountered in the attempted description on the 'nature' of the chemical bond, e.g., the forces involved. In order to avoid these difficulties an extension of the donor-acceptor concept, characterized by the comparison between equilibrium structures in different molecular environments, will be presented in this book. In this way, changes in the positions of the nuclei can be taken into account and the question of the nature of the molecular forces is no longer important.…

Taschenbuch. Condición: Neu. Neuware -Recent developments in various areas of chemistry have been decisively influenced by the principles of structure and mechanism and by the ideas of coordination chemistry, in particular by the donor-acceptor approach, A unified view of almost all kinds of molecular forces is provided by quantum mechanics, and for practical purposes have been classified according to model assumptions, namely, dispersion, polarization, electrostatic, and short-range forces. The latter are divided into two- and three-center covalent chemical bonds, metallic bonds, and exchange-repulsion forces. This approach allows statements of principle and systematic analysis. However, quantitative predictions on concrete large systems are virtually impossible, and there are no general rules that account for structural and chemical changes due to intermolecular interactions. Chemists are therefore left with qualitative descriptions in which the changes in electron densities are considered. Such models as the MO theory or the resonance concept unrealistically assume that the nuclei remain in fixed positions. Further difficulties are encountered in the attempted description on the 'nature' of the chemical bond, e.g., the forces involved. In order to avoid these difficulties an extension of the donor-acceptor concept, characterized by the comparison between equilibrium structures in different molecular environments, will be presented in this book. In this way, changes in the positions of the nuclei can be taken into account and the question of the nature of the molecular forces is no longer important.Springer Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 296 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - A: Biochemistry of Platinum Complexes in Cancer Chemotherapy.- B: Pharmacological Mechanisms and Toxicology of Platinum Complexes as Antitumor Agents.- C: Clinical Applications of Platinum Complexes.- D: Advances in Antitumor Research with Platinum and Non-Platinum Complexes; Development of New Metal Coordination Compounds: Synthesis and Characterization.- Author Index.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent developments in various areas of chemistry have been decisively influenced by the principles of structure and mechanism and by the ideas of coordination chemistry, in particular by the donor-acceptor approach, A unified view of almost all kinds of molecular forces is provided by quantum mechanics, and for practical purposes have been classified according to model assumptions, namely, dispersion, polarization, electrostatic, and short-range forces. The latter are divided into two- and three-center covalent chemical bonds, metallic bonds, and exchange-repulsion forces. This approach allows statements of principle and systematic analysis. However, quantitative predictions on concrete large systems are virtually impossible, and there are no general rules that account for structural and chemical changes due to intermolecular interactions. Chemists are therefore left with qualitative descriptions in which the changes in electron densities are considered. Such models as the MO theory or the resonance concept unrealistically assume that the nuclei remain in fixed positions. Further difficulties are encountered in the attempted description on the 'nature' of the chemical bond, e.g., the forces involved. In order to avoid these difficulties an extension of the donor-acceptor concept, characterized by the comparison between equilibrium structures in different molecular environments, will be presented in this book. In this way, changes in the positions of the nuclei can be taken into account and the question of the nature of the molecular forces is no longer important. 296 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Space missions subject human beings or any other target of a spacecraft to a radiation environment of an intensity and composition not available on earth. Whereas for missions in low earth orbit (LEO), such as those using the Space Shuttle or Space Station scenario, radiation exposure guidelines have been developed and have been adopted by spacefaring agencies, for exploratory class missions that will take the space travellers outside the protective confines of the geomagnetic field sufficient guidelines for radiation protection are still outstanding. For a piloted Mars mission, the whole concept of radiation protection needs to be reconsidered. Since there is an increasing interest of many nations and space agencies in establishing a lunar base and lor exploring Mars by manned missions, it is both, timely and important to develop appropriate risk estimates and radiation protection guidelines which will have an influence on the design and structure of space vehicles and habitation areas of the extraterrestrial settlements. This book is the result of a multidisciplinary effort to assess the state of art in our knowledge on the radiation situation during deep space missions and on the impact of this complex radiation environment on the space traveller. It comprises the lectures by the faculty members as well as short contributions by the students given at the NATO Advanced Study Institute 'Biological Effects and Physics of Solar and Galactic Cosmic Radiation' held in Armacao de Pera, Portugal, 12-23 October, 1991. 960 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the past decade there has been a dramatic expansion of our knowledge on phospholipases in general, and phospholipase A2 (PLA2) in particular. Progress in this field has been evident on many fronts, with novel information rapidly accumulating in the literature regarding the chemistry and molecular biology of this enzyme and its role in many important physiological processes. These include cellular signal transduction via the G-protein cycle, and in the generation of many cellular mediators, such as the platelet activating factor (PAF) and the eicosanoids that participate in the initiation and propagation of inflammation, to mention a few. This symposium was organized to obtain an overview of current investigations on this enzyme from the standpoint of its chemistry, molecular biology and physiology. Another important focus of this symposium concerns the regulation of PLA2, including endogenous and synthetic inhibitors and activators of this enzyme. To review these important areas in PLA2 research we invited scientists who made significant contributions in this field. The papers in this volume are organized to emphasize the recent advances in several areas of investigation, including: (I) the structure and mechanism of action of PLA2, (2) mechanism of activation of PLA2, (3) molecular biology, physiology and endogenous inhibitors of this enzyme and finally, (4) clinical investigations emphasizing the pathophysiological role of this enzyme in human diseases. The first article in this volume is by Dr. 280 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Space missions subject human beings or any other target of a spacecraft to a radiation environment of an intensity and composition not available on earth. Whereas for missions in low earth orbit (LEO), such as those using the Space Shuttle or Space Station scenario, radiation exposure guidelines have been developed and have been adopted by spacefaring agencies, for exploratory class missions that will take the space travellers outside the protective confines of the geomagnetic field sufficient guidelines for radiation protection are still outstanding. For a piloted Mars mission, the whole concept of radiation protection needs to be reconsidered. Since there is an increasing interest ci many nations and space agencies in establishing a lunar base and lor exploring Mars by manned missions, it is both, timely and important to develop appropriate risk estimates and radiation protection guidelines which will have an influence on the design and structure of space vehicles and habitation areas of the extraterrestrial settlements. This book is the result of a multidisciplinary effort to assess the state of art in our knowledge on the radiation situation during deep space missions and on the impact of this complex radiation environment on the space traveller. ]t comprises the lectures by the faculty members as well as short contributions by the students given at the NATO Advanced Study Institute 'Biological Effects and Physics of Solar and Galactic Cosmic Radiation' held in Armacao de Pera, Portugal, 12-23 October, 1991. 352 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We are most gratified by the response to the initiation of this series of volumes presenting recent developments and new concepts in microbial ecology. Favorable reactions have been expressed in both oral and written communication, and Ad vances in Microbial Ecology thus seems to be providing a worthwhile outlet in a rapidly growing field of microbiology and environmental sciences. The growing importance of microbial ecology is evident in many ways. Uni versity personnel are expanding their programs and increasing the number of research topics and publications. Substantial numbers of industrial scientists have likewise entered this field as they consider the microbial transformation of chemicals in waters and soils and the effects of synthetic compounds on natural microbial communities. Agricultural, medical, dental, and veterinary practitioners and scientists have also been increasing their activity in microbial ecology because of the importance of the discipline to their own professions. In addition, govern mental agencies have expanded regulatory and research activities concerned with microbial ecology owing to the importance of information and regulations fo cused on the interactions between microorganisms in nature and particular en vironmental stresses. 240 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the past two decades professional interest in Terminal Care has increased dramatically. It is always difficult to trace the origins of a change of emphasis in medical and nursing care but it is likely that three influences have contributed to bring this about. Firstly, the rise of the modern hospice movement with its recognition that dying and mourning are normal life events and that the lay person has a role in these events no less important than the health professional; secondly, the development of sophisticated and successful techniques of palliative care and pain control; and lastly, the increasing expectations of the populace in advanced countries for a comprehensive and sensitive service for patients, family and care givers at the terminal phase of illness. It is significant that these developments in the care and management of the terminally ill are not confined either to one country or the sole prerogative of a single discipline. This is reflected in the papers collected in this volume which were originally presented at the International Conference on Multidisciplinary Aspects of Terminal Care organised by The Prince and Princess of Wales Hospice in Glasgow, Scotland, U.K. The cross-fertilisation of ideas, experiences, and assessments provided by the contributors in a multicultural and multidisciplinary context pre sented in this volume will be found stimulating and inspirational for both the professional and the lay person in the care of the dying. 232 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -1 Vitamin-Responsive Inherited Metabolic Disorders.- Vitamin Deficiency: Historical Perspective.- Vitamin Responsiveness or Dependency.- Genetic Control of Vitamin Metabolism.- Biochemical Role of Vitamins.- Effect of Mutation on Vitamin Function: Theoretical Possibilities.- Defects of Vitamin Transport and Coenzyme Synthesis.- Cobalamin (Vitamin B12).- Folic Acid.- Calciferol (Vitamin D).- Defects of Coenzyme-Dependent Apoenzymes.- Pyridoxine (Vitamin B6).- Biotin.- Thiamine (Vitamin B1).- Genetic Heterogeneity.- Clinical Panorama.- Mendelian Inheritance.- Prenatal Detection and Treatment.- Problems and Perspectives.- 2 Inherited Deficiency of Hypoxanthine-Guanine Phosphoribosyltransferase in X-Linked Uric Aciduria (the Lesch-Nyhan Syndrome and Its Variants).- Clinical Presentation.- Frequency.- Complete Syndrome.- Clinical Variants of the Syndrome.- Pathology.- Biochemical Characteristics.- Primary Enzyme Defect.- Secondary Enzyme Disturbances.- Properties of the Normal Enzyme.- Properties of the Mutant Enzyme.- Mechanism of Excessive Rate of Purine Synthesis.- Mechanism of Neurological Dysfunction.- Genetic Significance.- Genetic Heterogeneity.- X-Linked Inheritance.- Chemical Selection.- Somatic Cell Genetics.- Preventive Control through Prenatal Diagnosis.- Characteristics of the Heterozygous State.- Pharmacological Consequences of HPRT Deficiency.- Diagnosis of X-Linked Uric Aciduria.- Clinical Signs.- Laboratory Tests.- Heterozygote Detection.- Treatment.- General Measures.- Medications.- 3 Hereditary Hemolytic Anemia Due to Enzyme Defects of Glycolysis.- Glucose Utilization by the Red Cell.- Overall Regulation of Glycolysis.- Mass Action Ratio.- Effect of Cell Age on Metabolism.- Molecular Genetic Mechanisms of Enzyme Deficiency.- Expression of Enzyme Defects in the Red Cell and Other Tissues.- Hexokinase Deficiency.- Clinical Spectrum.- Biochemical Considerations.- Genetic Considerations.- Glucosephosphate Isomerase Deficiency.- Clinical Spectrum.- Biochemical Considerations.- Genetic Considerations.- Phosphofructokinase Deficiency.- Clinical Spectrum.- Biochemical Considerations.- Genetic Considerations.- Phosphoglycerate Kinase Deficiency.- Clinical Spectrum.- Biochemical Considerations.- Genetic Considerations.- Pyruvate Kinase Deficiency.- Clinical Spectrum.- Biochemical Considerations.- Genetic Considerations.- Other Defects of Glycolytic Enzymes in the Red Cells.- Triosephosphate Isomerase Deficiency.- Glyceraldehyde-3-phosphate Dehydrogenase Deficiency.- 2,3-Diphosphoglycerate Mutase Deficiency.- Lactate Dehydrogenase Deficiency.- 4 Population Structure of the ¿and Islands, Finland.- ¿and.- Location and Description.- History.- Population Composition.- Migration Analyses.- Kinship and Population Structure.- The Migration Matrix Model.- Matrimonial Migration in ¿and.- Parish Endogamy.- Prediction of Kinship from Matrimonial Migration Data.- Approach to Equilibrium.- Kinship Matrices.- Geographical Factors Affecting Migration Patterns.- Isolation by Distance.- Summary.- Topology of Population Structure.- 1750¿1799.- 1800¿1849.- 1850¿1899.- 1900¿1909.- 1910¿1919.- 1920¿1929.- 1930¿1939.- 1940¿1949.- 1900¿1949.- The Inclusion of Mariehamn.- Correlation between Coordinates.- Summary of Topology.- Discussion of Migration Analyses.- Biological Studies.- Genetic Analyses.- Geography and Genetic Structure.- Comparison of Genetic and Migration Inference.- Twinning in and around ¿and.- Ophthalmological Studies.- The ¿and Bleeder Syndrome (von Willebrand-J¿rgens).- 5 Population Genetics and Health Care Delivery: The Quebec Experience.- A Short History of French Canada.- A Consanguinity Study.- Objectives.- Demographic Aspect.- Sources and Material.- Results.- Discussion: Consanguinity and the Mean Coefficient Fw.- Conclusions and Decisions.- An Isolate Study.- Objectives.- Methods.- Results.- Conclusions and Decisions.- An Inbreeding Study.- Objectives.- M.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The time seems ripe for a critical compendium of that segment of the biological universe we call viruses. Virology, as a science, having passed only recently through its descriptive phase of naming and numbering, has probably reached that stage at which relatively few new-truly new-viruses will be discovered. Triggered by the intellectual probes and techniques of molecular biology, genetics, bio chemical cytology, and high resolution microscopy and spectroscopy, the field has experienced a genuine information explosion. Few serious attempts have been made to chronicle these events. This comprehensive series, which will comprise some 6000 pages in a total of 19 volumes, represents a commitment by a large group of active investigators to analyze, digest, and expostulate on the great mass of data relating to viruses, much of which is now amorphous and disjointed, and scattered throughout a wide literature. In this way, we hope to place the entire field in perspective, and to develop an invaluable reference and sourcebook for researchers and students at all levels. This series is designed as a continuum that can be entered any where, but which also provides a logical progression of developing facts and integrated concepts. 560 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Recent developments in various areas of chemistry have been decisively influenced by the principles of structure and mechanism and by the ideas of coordination chemistry, in particular by the donor-acceptor approach, A unified view of almost all kinds of molecular forces is provided by quantum mechanics, and for practical purposes have been classified according to model assumptions, namely, dispersion, polarization, electrostatic, and short-range forces. The latter are divided into two- and three-center covalent chemical bonds, metallic bonds, and exchange-repulsion forces. This approach allows statements of principle and systematic analysis. However, quantitative predictions on concrete large systems are virtually impossible, and there are no general rules that account for structural and chemical changes due to intermolecular interactions. Chemists are therefore left with qualitative descriptions in which the changes in electron densities are considered. Such models as the MO theory or the resonance concept unrealistically assume that the nuclei remain in fixed positions. Further difficulties are encountered in the attempted description on the 'nature' of the chemical bond, e.g., the forces involved. In order to avoid these difficulties an extension of the donor-acceptor concept, characterized by the comparison between equilibrium structures in different molecular environments, will be presented in this book. In this way, changes in the positions of the nuclei can be taken into account and the question of the nature of the molecular forces is no longer important. 296 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents the proceedings of the Third International Symposium on Acoustical Holography, which was held at the Newporter Inn, Newport Beach, on 29-31 July 1970. The symposium was sponsored by the Douglas Advanced Research Laboratories, McDonnell Douglas Corporation, and the Acoustical Society of America. Twenty papers were presented and these each appear as a chapter in this volume. The chapters are grouped into five sections. The sections are I Medical and Biolog ical, II Bragg Imaging, III Nondestructive Testing, IV Underwater and Long Wavelength, and V Theory and Methods. The reader is cautioned only to use the sec tional titles as a rough guide. For instance, the reader interested in new methods should not just read section V since he will find a new liquid surface relief method de scribed in chapter lOin section III. In an effort to reduce the time delay between the meeting and the publication date, the publishers have pro duced this volume using the shoot-from-manuscript method instead of the mote time consuming typesetting method that was used on the previous volumes. As a result there may be differences in notation and definitions used for one chapter to another. However this should not cause con fusion since all symbols and definitions are stated in each chapter. The editor wishes to thank the session chairmen, Dr. Vincent Salmon, Stanford Research Institute; Dr. Isadore Rudnick, University of California at Los Angeles; Dr. Lewis Larmore, McDonnell Douglas Corporation; Dr. 420 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The II. International Conference on Ion Beam Surface Layer Analysis was held on September 15-19, 1975 at the Nuclear Research Center, Karlsruhe, Germany. The date fell between two related con ferences: 'Application of Ion-Beams to Materials' at Warwick, Eng land and 'Atomic Collisions in Solids' at Amsterdam, the Nether lands. The first conference on Ion Beam Surface Layer Analysis was held at Yorktown Heights, New York, 1973. The major topic of that and the present conference was the material analysis with ion beams including backscattering and channeling, nuclear reactions and ion induced X-rays with emphasis on technical problems and no vel applications. The increasing interest in this field was docu mented by 7 invited papers and 85 contributions which were presen ted at the meeting in Karlsruhe to about 150 participants from 21 countries. The oral presentations were followed by parallel ses sions on 'Fundamental Aspects', 'Analytical Problems' and 'Appli cations' encouraging detailed discussions on the topics of most current interest. Summaries of these sessions were presented by the discussion leaders to the whole conference. All invited and contributed papers are included in these proceedings; summaries of the discussion sessions will appear in a separate booklet and are availble from the editors. The application of ion beams to material analysis is now well established. 512 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The idea for the present volume grew from discussions that the four of us had among ourselves and with our colleagues at recent scientific meetings. All of us were impressed by the wealth of empirical data that was being generated by investigators interested in brain damage and recovery from both behavioral and biological orientations. Nevertheless, we were concerned about the relative paucity of attempts to evaluate the data provided by new technologies in more than a narrow context or to present new theories or reexamine time-honored ideas in the light of new findings. We recognized that science is guided by new technologies, by hard data, and by theories and ideas. Yet we were forced to conclude that, although investi gators were often anxious to publicize new methods and empirical fmdings, the same could not be said about broad hypotheses, underlying concepts, or in ferences and speculations that extended beyond the empirical data. Not only were many scientists not formally discussing the broad implications of their data, but, when stimulating ideas were presented, they were more likely to be heard in the halls or over a meal than in organized sessions at scientific meetings. 392 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -6 Ions can pass through a single membrane channel at a rate of 10 ions/second. Over the last decade the ability to measure ion flux so precisely and to document the opening and closing of individual ion channels has provided a powerful tool to those working on smooth muscle physiology and vascular reactivity. The use of potassium channel blockers by Tom Lloyd in the 1960s and calcium channel blockers by Ivan McMurtry in the 1970s indicated the importance of ion flux in regulating pulmonary vascular tone. Recent advances in technology. principally the patch-clamp technique and fluorescent ion-sensitive dyes. now permit a more detailed description of physiologic mechanisms. This volume arises from the Sixth Grover Conference on the Pulmonary Circulation. a NATO Advanced Research Workshop. held in Colorado in October 1992. A group of international sCientists who are leaders in the field of ion flux focused their attention on the problems of the pulmonary vasculature. The chapters in this book describe the present state of knowledge of the movement and storage of ions in vascular endothelial and smooth muscle cells. Those who are not familiar with the techniques of patch clamping and calcium imaging will find an introduction to these methods in the chapters by Leblanc and Wan and Archer et al. The role of potassium channels in oxygen sensing illustrates the rapid progress which the study of ion currents has made possible. 360 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Alcohol abuse is this culture's most important drug problem. Statistics indicate that it is exacting a great and relentlessly increasing toll of human suffering. It is clear that the problem is not being dealt with in any effective manner. At the invitation of the. Canadian Hepatic Foundation, many of the world's experts gathered in Toronto, May 14-15 1976, to focus attention on one of the most important aspects of the alcohol problem -alcohol induced liver damage. The epidemiology of alcohol induced liver disease was discussed and current views on the pathogenesis of the problem were reviewed. New insight into the pathological alterations of the liver was presented and some of our current therapeutic capabilities were discussed. Dr. Hans Popper summarized the Symposium and presented some of his views on those aspects of the problem which will require early attention by the research community. The Symposium achieved its immediate objective -that of bringing together the committed experts of various disciplines for an updating of our understanding of alcohol and the liver and for a discussion of new approaches to the problem. As a backdrop to the Symposium, however, was large writing on the wall to the effect that we are expending our research talents and efforts on a totally unnecessary problem. Right now we probably know enough and have sufficient resources at our disposal to solve the problem. 420 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The first chapter of this volume deals with computer simulation of molten salt behavior by molecular dynamics calculations. The next four chapters are reviews of experimental work: Chapter 2 deals with the solubility of nonre active gases in molten salts, Chapter 3 with various types of organic reactions in molten tetrachloroaluminates, Chapter 4 with techniques for the study of molten fluorides, and Chapter 5 with the physical and chemical properties of thiocyanate melts. The last chapter is a collection of phase diagrams for binary and ternary fluoride systems. J. B., G. M., G. P. S. v CONTENTS Chapter 1 MOLECULAR DYNAMICS CALCULATIONS ON MOLTEN IONIC SALTS L. V. Woodcock 1. Introduction. . 4 2. Intermolecular Forces in Molten Salts 4 2.1. True and Effective Pair Potentials 2.2. Semiempirical Models 6 3. Computational Techniques 13 3.1. Molecular Dynamics Simulation 13 3.2. The Monte Carlo Method 15 3.3. Electrostatic Summations . . 18 4. Calculation of Physical Properties 23 4.1. Equilibrium Properties . 23 4.2. Transport Coefficients 27 4.3. Spectroscopic Properties 32 5. Applications. . . . . . . . 35 5.1. Studies of Interionic Forces. 35 5.2. Microstructure and Mechanisms 40 5.3. Interpretation of Experimental Observables 50 5.4. Reappraisal of Molten Salt Theories . 64 70 6. Conclusions 7. References. 72 vii Contents viii Chapter 2 GAS SOLUBILITY IN MOLTEN SALTS P. Field 1. Introduction 75 2. Experimental Techniques 78 3. Solution Thermodynamics. 476 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The meeting on experimental hepatocarcinogenesis which took place in Spa, Belgium at the end of May 1987 was the Second European Meeting. About 100 scientists, mostly from Europe but also from the United States, met there for three days in a very friendly atmosphere to exchange knowledge and ideas on experimental and human liver carcinogenesis. The main topics discussed during the meeting included general reviews on hepatocarcinogenesis, experimental models of hepa tocarcinogenesis, biology of hepatocarcinogenesis, and in vitro studies in hepatocarcinogenesis. They are all covered by the various chapters of this proceedings volume, which reflects the present state of knowledge in this important field of cancer research. The final aim of that research is to understand the basic mechanisms of carcinogenesis. The liver offers a parti cularly interesting tool to reach such a goal. Indeed, its biochemistry, its morphology, and its physiology are very diverse, but relatively well known. Various protocols have been developed to produce hepatocellular carcinomas or other malignant tumors. Their appearance is most often preceded by phenotypically altered foci and nodules which have been isolated and characterized. The major cell populations of normal, neoplastic, and malignant livers have been cultivated. 336 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The second volume of Condensed Matter Theories contains the proceedings of the 10th International Workshop held at Argonne National Laboratory, Argonne, IL, U.S.A. during the week of July 21, 1986. The workshop was attended by high-energy, nuclear and condensed-matter physicists as well as materials scientists. This diverse blend of participants was in keeping with the flavor of the previous workshops. This annual series of international workshops was'started in 1977 in Sao Paulo, Brazil. Subsequent'workshops were held in Trieste (Italy), Buenos Aires (Argentina), Caracas (Venezuela), Altenberg (West Germany), Granada (Spain), and San Francisco (U.S.A.). What began as a meeting of the physicists from the Western Hemisphere has expanded in the last three years into an international conference of scientists with diverse interests and backgrounds. This diversity has promoted a healthy exchange of ideas from different branches of physics and also fruitful interactions among the participants. The present volume is a continuation of the effort started last year when the invited papers from the 9th International Workshop were published by Plenum Press. Our only trepidation in organizing a book of this kind stemmed from the diversity of the material, which did not lend itself easily to well-defined topics. Still, the articles are loosely divided into eight categories, where the papers in each category have either a common theme or the same underlying technique. 424 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -General Editor: Peter Calow, Department of Zoology, University of Sheffield, England The main aim of this series will be to illustrate and to explain the way organisms 'make a living' in nature. At the heart of this - their functional biology - is the way organisms acquire and then make use of resources in metabolism, movement, growth, reproduction, and so on. These processes will form the fundamental framework of all the books in the series. Each book will concentrate on a particular taxon (species, family, class or even phylum) and will bring together information on the form, physiology, ecology and evolutionary biology of the group. The aim will be not only to describe how organisms work, but also to consider why they have come to work in that way. By concentrating on taxa which are well known, it is hoped that the series will not only illustrate the success of selection, but also show the constraints imposed upon it by the physiological, morpho logical and developmentallimhations of the groups. Another important feature of the series will be its organismic orientation. Each book will emphasise the importance of functional integration in the day-to-day lives and the evolution of organisms. This is crucial since, though it may be true that organisms can be considered as collections of gene-determined traits, they neverthe less interact with their environment as integrated wholes and it is in this context that individual traits have been subjected to natural selection and have evolved. 208 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A FEW DAYS after Smetana's body had been laid to rest in the Vysehrad Cemetery, Prague, Franz Liszt sent word to Karel Navrlitil: 'In haste I write to tell you that the death of Smetana has deeply affected me. He was indeed a genius!' Ironically, with his death Smetana was proclaimed the founder of modern Czech music, but only a few years before he had been spurned, labelled 'Wagnerian' and accused of impeding the way of musical progress. Like Verdi, Smetana was a confirmed patriot. Dramatic music was his platform and his greatest ambition was to see the Prague National Theatre become the permanent home of Czech opera. This he witnessed, but not without making countless enemies and spending years of bitterness in arduous struggle. Smetana's life was one long struggle and sadly he never lived to reap the rewards of his efforts. He developed late. Like Schumann, his early works were almost exclusively for the piano: like Dostoevsky, his first important essay appeared only in middle life. His was relatively small. Few of his. scores found their way into print and, output apart from The Bartered Bride and The Kiss, little of his music was performed with any regularity during his life. After ten busy years, during which he wrote five operas and worked as Musical Director of the Prague Provisional Theatre, he was halted by deafness. There followed a further ten years in which illness and mental disorder made composition increasingly difficult. 524 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Dr. Maurizio Andolfi, 'Andi' to my dog and me, is one of the fourth generation family therapy theorists. This book, which he calls 'interac tional,' is probably one you would not enjoy. Maybe you could give it to a rival colleague on his birthday. Combining the teachings of Zwerling and Laperriere with Ferber is confusing. Add to that a Horney analysis and stir with two ounces of Minuchin and a dram of Haley, and Andolfi becomes distracting to his friends and colleagues. His work with Can crini reacculturated him somewhat, but a Roman is a Roman, and, of course, he could not understand such problems as those we conquer in the United States. Assuming your rival is a well-trained, cause-and-effect thinker, you might find ways to watch him squirm. If he has not tried paradoxical methods, expect him to take a long vacation from work. If he is already a good family therapist, he may become a bit hypomanic, and his team may talk to you in private. Encourage them to suggest that he work harder and stop reading the book or, better still, donate it to the social work school library; they will read anything. If the team complains that the book advises teaching sick families how to be their own therapists, resist any impulse to check this out. No family could become self reparative when it is already dysfunctional. We know that professional help is the only hope. 192 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The concept of chemical transmission in the central nervous system has taken some time to be generally accepted, but an increasing number of compounds are now being recognized as hav ing a transmitter role in the brain. The acetylcholine system was the first to be discovered in the periphery and its charac teristic features of storage of transmitter in vesicles in the nerve terminal, its electrically-evoked release and rapid extra neuronal breakdown were considered to be necessary criteria for any neurotransmitter candidate. The subsequent elucidation of the noradrenergic system made it apparent that rapid enzymatic breakdown was not essential for a released transmitter, and the possibility of high-affinity re-uptake processes became establ ished as an alternative means of terminating the synaptic actions of a transmitter. With the eventual acceptance of the amino acids as excitat ory or inhibitory transmitters, the requirement for a transmit ter to be present in a low concentration overall (although locally concentrated in specific terminals) also had to be discarded. This necessitated the additional concept of specif ic metabolic pools with different functions being located in different cells or within different regions of the same cell. Some localization of glutamate and aspartate remote from excit able membranes is clearly essential since their overall brain concentrations would be sufficient to maximally depolarize the majority of neurones in the brain. The concept of separate metabolic pools has been supported by stUdies on turnover rate (see Chapter 5). 212 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book discusses how human beings cope with serious physical ill ness and injury. A conceptual model for understanding the process of coping with the crisis of illness is provided, and basic adaptive tasks and types of coping skills are identified. The major portion of the book is organized around various types of physical illness. These physical illnesses, which almost all people face either in themselves or their family members, raise common relevant coping issues. The last few sections cover 'the crisis of treatment,' emphasizing the importance of unusual hospital environments and radical new medical treatments, of stresses on professional staff, and of issues related to death and the fear of dying. The material highlights the fact that people can successfully cope with life crises such as major ill ness and inj ury, rather than the fact that severe symptoms and/or breakdowns sometimes occur. The importance of support from professional care-givers, such as physicians, nurses, and social workers, and from family, friends, and other sources of help in the community, is emphasized. Many of the selections include case examples which serve to illustrate the material. Coping with Physical Illness has been broadly conceived to meet the needs of a diverse audience. There is substantial information about how human beings cope with illness and physical disability, but this material has never been collected in one place. 456 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We respectfully submit these proceedings of the 1982 Orbis Scientiae for your reading enjoyment. As always, the success of the conference was due to the hard work and wisdom of the moderators and dissertators. This year, in addition to the excellent overview of QCD and GUT, and the customary reports of the latest progress in theoretical and experimental particle physics, there have been discussions of new developments in astrophysics and especially of field theory and composite models. We wish also to note here that the 1981 Orbis paper by Stephen S. Pinsky on 'Death of Fractional Topological Charge' was actually co-authored by William F. Palmer of Ohio State University, whose name was inadvertently omitted from the authorship, due to a series of misunderstandings. As in the past, this Orbis Scientiae 1982 was supported on a small scale by the Department of Energy, and this year as well by the National Science Foundation, on the same scale. We would like to thank Mrs. Helga S. Billings for her excellent typing for the n-th time, where n is a large number. This series of proceedings is also enhanced by Linda Scott's editorial help which includes improvements in the presentation of some of the papers. 480 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contains the proceedings of a symposium held at the College of Charleston. Charleston. South Carolina. USA. 16-20 June. 1986. The seed for this symposium arose from a group of physiologists. soil scientists and biochemists that met in Leningrad USSR in July 1975 at the 12th Botanical Conference in a Session organized by Professor B.B. Vartepetian. This group and others later conspired to contribute to a book entitled Plant Life in Anaerobic Environments (eds. D.D. Hook and R.M.M. Crawford. Ann Arbor Science. 1978). Several contributors to the book suggested in 1983 that a broad-scoped symposium on wetlands would be useful (a) in facilitating communication among the diverse research groups involved in wetlands research (b) in bringing researchers and managers together (c) and in presenting a comprehensive and balanced coverage on the status of ecology and management of wetlands from a global perspective. With this encouragement. the senior editor organized a planning committee that encompassed expertise from many disciplines of wetland scientists and managers. This committee, with input from their colleagues around the world, organized a symposium that addressed almost every aspect of wetland ecology and management. 420 pp. Englisch. …

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Biodeterioration held April 20-23, 1981, at the Uniformed Services University of the Health Sciences, Bethesda, Maryland. The symposium was sponsored by the Office of Naval Research to provide an organized forum for the discussion of progress in basic and applied research con cerning marine biodeterioration. The symposium was structured to cover interdisciplinary topics of interest both to the basic research community and the applied science and engineering communities. In each major topic area, a comprehensive overview paper summarizing highlights of the past two decades of research is followed by current technical papers concerning both basic and applied re search. Authors were urged to provide extensive refer ences, and their papers were subjected to external peer review. In some respects, the symposium was structured to pro vide a reference tool for the marine engineering com munity that would supplement the excellent monograph entitled 'Marine Fouling and Its Prevention' prepared for the U.S. Navy Bureau of Ships in 1952 by the Woods Hole Oceanographic Institution. While these proceedings can not begin to update that work, they can, by presenting the in research direction, recent workers in the field, changes ac and current references, give the interdisciplinary user cess to the current literature in key topic areas. 412 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The purpose of this series is to provide a continuing critical review of the literature concerned with mechanistic aspects of inorganic and organo metallic reactions in solution, with coverage being complete in each volume. The papers discussed are selected on the basis of relevance to the elucidation of reaction mechanisms and many include results of a nonkinetic nature when useful mechanistic information can be deduced. The period of literature covered by this volume is July 1982 through December 1983, and in some instances papers not available for inclusion in the previous volume are also included. Numerical results are usually reported in the units used by the original authors, except where data from different papers are com pared and conversion to common units is necessary. As in previous volumes material included covers the major areas of redox processes, reactions of the nonmetallic elements, reaction of inert and labile metal complexes and the reactions of organometallic compounds. While maintaining the space devoted to other areas, that given to the nonmetallic elements has been increased. In recognition of the increasing importance of the determination of volumes of activation in understanding the mechanisms of both inorganic and organometallic reactions a special reference section giving tabulated Ll V\* values has been included and this extensive compilation will be updated in future volumes. 540 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book by Kaplan and Vekhter brings together the molecular world of the chemist with the condensed matter world of the physicist. Prior to the collapse of the Soviet Union, chemists in the West devoted lit to relationships between molecular electronic structure and tle attention solid-state vibronic phenomena. Treating quantum mechanical problems wherein the adiabatic Born-Oppenheimer approximation fails was done by 'brute force. ' With bigger and better computers available in the West, molecular orbital calculations were done on observed and conceived static structures with little concern for any cooperativity of vibrational behavior that might connect these states. While it had long been understood in the West that situations do occur in which different static structures are found for molecules that have identical or nearly identical electronic structures, little attention had been paid to understanding the vibrational states that could connect such structures. It was easier to calculate the electronic structure observed with several possible distortions than to focus on ways to couple electronic and vibrational behavior. In the former Soviet Union, computational power was not as acces sible as in the West. Much greater attention, therefore, was devoted to conserving computational time by considering fundamental ways to han dle the vibrational connectivity between degenerate or nearly degenerate electronic states. 444 pp. Englisch.…