Springer springer sep 2016 (Más de 6200 resultados)

Buch. Condición: Neu. Neuware -This book trains the next generation of scientists representing different disciplines to leverage the data generated during routine patient care. It formulates a more complete lexicon of evidence-based recommendations and support shared, ethical decision making by doctors with their patients. Diagnostic and therapeutic technologies continue to evolve rapidly, and both individual practitioners and clinical teams face increasingly complex ethical decisions. Unfortunately, the current state of medical knowledge does not provide the guidance to make the majority of clinical decisions on the basis of evidence. The present research infrastructure is inefficient and frequently produces unreliable results that cannot be replicated. Even randomized controlled trials (RCTs), the traditional gold standards of the research reliability hierarchy, are not without limitations. They can be costly, labor intensive, and slow, and can return results that are seldom generalizable to every patient population. Furthermore, many pertinent but unresolved clinical and medical systems issues do not seem to have attracted the interest of the research enterprise, which has come to focus instead on cellular and molecular investigations and single-agent (e.g., a drug or device) effects. For clinicians, the end result is a bit of a 'data desert' when it comes to making decisions. The new research infrastructure proposed in this book will help the medical profession to make ethically sound and well informed decisions for their patients. 452 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware -In dem vorliegenden Buch beleuchtet der langjährig erfahrene Psychotherapeut und Vorsitzende einer Hospizbewegung, Professor Knud Eike Buchmann, psychologische Aspekte in Bezug auf das eigene Sterben und den eigenen Tod. Er geht dabei Fragen nach wie: Wann und wie werde ich sterben Kann ich mich auf das Sterben vorbereiten Gibt es das Nichts nach dem Tod und wie lässt sich mit der Trauer umgehen Professor Buchmann zeigt anhand zahlreicher konkreter Beispiele wie es gelingt, mit einem klaren Konzept und einer bewussten Haltung dem Lebensende gelassen und angstfrei entgegen zu sehen. Das Werk wendet sich an alle, die sich mit dem eigenen Sterben, dem eigenen Tod und der Trauer auseinandersetzen möchten, aber auch an Angehörige und Hinterbliebene. 196 pp. Deutsch.…

Taschenbuch. Condición: Neu. Neuware -This book describes a novel approach for the design of embedded systems and industrial automation systems, using a unified model-driven approach that is applicable in both domains. The authors illustrate their methodology, using the IEC 61499 standard as the main vehicle for specification, verification, static timing analysis and automated code synthesis. The well-known synchronous approach is used as the main vehicle for defining an unambiguous semantics that ensures determinism and deadlock freedom. The proposed approach also ensures very efficient implementations either on small-scale embedded devices or on industry-scale programmable automation controllers (PACs). It can be used for both centralized and distributed implementations. Significantly, the proposed approach can be used without the need for any run-time support. This approach, for the first time, blurs the gap between embedded systems and automation systems and can be applied in wide-ranging applications in automotive, robotics, and industrial control systems. Several realistic examples are used to demonstrate for readers how the methodology can enable them to reduce the time-to-market, while improving the design quality and productivity. 212 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware -This book discusses the impact and effects of Information and Communication Technologies (ICT) on quality of working life of employees. It describes the changes and the acceleration of processes caused by the widespread use of ICT in a broad range of working areas and in different national contexts. It explores the important role ICT has come to play in nearly all work places in developed societies and the impact it is starting to have on work places in developing countries. The book brings together experts from the fields of ICT and quality of working life and from a variety of backgrounds and disciplines, including sociology, psychology, industrial engineering and macro ergonomics. It discusses the range of current positive and negatives effects as well as the possible increase of both kinds of effects in the future. The final chapter of the book integrates the diverse perspectives of the authors and gives recommendations on how to increase the possible positive outcomes and to diminish negative effects of ICT in an accelerated society. 244 pp. Englisch.…

Buch. Condición: Neu. Neuware -This book provides a theoretical, empirical, and pragmatic understanding of social dilemmas (SDs). A SD is a social situation where cooperation maximizing collective or social profit is different from defection maximizing individual profit. Problems arise when too many group members choose to pursue individual profit and immediate satisfaction rather than behave in the group's best long-term interests. The problems include an environmental problem and various types of urban, economic, and political problems. Most books treating SDs are not monographs but are proceedings or omnibus volumes written by different researchers. Few monographs have been published for SDs, but those few deal only with basic theories and empirical findings. This book, by contrast, is a monograph by a single author and provides complete coverage from basic theories in Part I to applied theories and pragmatic solutions for urban, transportation, and environmental problems in Parts II and III. Various types of strategies are proposed in this book to overcome the problems caused by SDs in various situations based on the basic theories of those dilemmas. The strategies are psychological and structural ones. The book includes theories, empirical evidence in experiments, and practical policies in the real world for these strategies. Thus, the work effectively provides a bridge between basic behavioral scientists, applied behavioral scientists, and practitioners. With this useful source, basic scientists will understand how to apply their scientific knowledge to the real world and also will encounter new scientific problems that should be solved scientifically. Applied researchers and specialists will become familiar with new solutions through basic research on SDs and will be made aware of new pragmatic problems that should be solved with a practical approach. 232 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware -This important volume provides a holistic understanding of the cultural, psychological, neurological and biological elements involved in human facial expressions and of computational models in the analyses of expressions. It includes methodological and technical discussions by leading scholars across the world on the subject. Automated and manual analysis of facial expressions, involving cultural, gender, age and other variables, is a growing and important area of research with important implications for cross-cultural interaction and communication of emotion, including security and clinical studies. This volume also provides a broad framework for the understanding of facial expressions of emotion with inputs drawn from the behavioural sciences, computational sciences and neurosciences.…

Taschenbuch. Condición: Neu. Neuware -Thermodynamik kompakt stellt den Lehrstoff der Thermodynamik in kurzer und prägnanter Weise dar. Den Autoren gelingt es, die Sachverhalte inhaltlich auf hohem Niveau, aber gut verständlich zu vermitteln. Die Studierenden lernen so, das Wichtige vom Nebensächlichen zu unterscheiden. Das Buch beschreitet neue Wege in der Präsentation des Stoffes. So werden Bilanzgleichungen allgemein betrachtet, und es wird relativ früh auf das thermische und kalorische Verhalten der Stoffe eingegangen. Das ideale Gas und das reale Gasverhalten werden parallel für verschiedene Anwendungen gezeigt. Zahlreiche Verständnisfragen vertiefen den Stoff. Mehrere Anwendungskapitel runden das Buch ab und verdeutlichen, wozu die theoretischen Gleichungen verwendet werden. 3D-Animationen und weiteres Bildmaterial im Internet dienen der Veranschaulichung.Die Darstellungen der früheren Auflagen haben sich bewährt. Für die vierte Auflage wurden verschiedene Korrekturen durchgeführt, der Text an mehreren Stellen präzisiert und Bilder angepasst. Weiterhin wurden Schreibfehler im Text und in den Gleichungen beseitigt.Der InhaltEinleitung.- Grundlagen.- Hauptsätze der Thermodynamik.- Stoffe und deren thermodynamische Beschreibung.- Anwendungen der Hauptsätze.- Maximale Arbeit und Exergie.- Technische Anwendungen.Die Zielgruppen Studierendeim dritten und vierten Semester an Universitäten und Fachhochschulen.Die AutorenBernhard Weigand ist seit 1999 Professor am Institut für Thermodynamik der Luft- und Raumfahrt der Universität Stuttgart. Jürgen Köhler ist seit 1998 Professor für Thermodynamik in der Fakultät für Maschinenbau der Technischen Universität Braunschweig. Jens von Wolfersdorf ist seit 2001 Professor am Institut für Thermodynamik der Luft- und Raumfahrt an der Universität Stuttgart. 236 pp. Deutsch.…

Taschenbuch. Condición: Neu. Neuware -Dieses Buch hilft Patienten und Angehörigen, schizophrene Psychosen besser zu verstehen. Es erklärt die Symptome dieser Erkrankung, ihre möglichen Ursachen und ihre Behandlung, aber auch wie sie verläuft und wie man sich davor besser schützen kann. Schizophren erkrankte Menschen müssen oft mit dem Stigma leben, das diese Störung in unserer Gesellschaft immer noch hat. Angehörige sind vielfach überfordert und wissen sich häufig nicht zu helfen. Umso wichtiger ist eine umfassende Information über die Erkrankung durch erfahrene Experten. Dabei bleibt das Buch aber nicht stehen. Es befasst sich ausführlich mit schwierigen Alltagssituationen und gibt Hinweise für den Umgang mit Alltagsnöten.Das Buch ist aus der Zusammenarbeit mit Schizophreniekranken und ihren Angehörigen entstanden. Es ist sehr verständlich geschrieben. Die Kapitel können auch einzeln gelesen werden.Aus dem InhaltVerbreitete Vorurteile: psychotisches Erleben, was ist anders - Ursachenforschung - Welche Therapie für welches Problem - Ansätze zur Selbsthilfe - Anleitung und Unterstützung für Angehörige im Umgang mit schizophren erkrankten Familienmitgliedern - Glossar der wichtigsten Krankheits- und Fachbegriffe.Die Autoren Professor em. Dr. med. Daniel Hell, langjähriger ärztlicher Direktor der Psychiatrischen Universitätsklinik Zürich, an der Privatklinik Hohenegg am Zürichsee tätig. Privat-Dozent Dr. med. Daniel Schüpbach, Chefarzt, Klinikum am Weissenhof, Akademisches Lehrkrankenhaus der Universität Heidelberg. Deutsch.…

Buch. Condición: Neu. Neuware -With an emphasis on exploring measurable aspects of ancient narratives, Maths Meets Myths sets out to investigate age-old material with new techniques. This book collects, for the first time, novel quantitative approaches to studying sources from the past, such as chronicles, epics, folktales, and myths. It contributes significantly to recent efforts in bringing together natural scientists and humanities scholars in investigations aimed at achieving greater understanding of our cultural inheritance.Accordingly, each contribution reports on a modern quantitative approach applicable to narrative sources from the past, or describes those which would be amenable to such treatment and why they are important.This volume is a unique state-of-the-art compendium on an emerging research field which also addresses anyone with interests in quantitative approaches to humanities. 242 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - The kidneys participate in all vital processes of the body to maintain overall homeostasis and health. When kidneys are injured during surgical interventions, metabolic and hemodynamic control is disrupted, leading to dysfunction associated with greater mortality, length of hospital stay and cost.Peri-operative Kidney Injury presents the epidemiology, risk factors, diagnosis, treatment and outcomes associated with kidney injury during the peri-operative period. Concepts and principles of care to prevent kidney complications during surgical procedures are provided to equip health care professionals along with strategies to manage acute kidney injury and associated challenges when they occur. Chapters detail diverse surgical settings, ranging from the more common, such as abdominal, cardiac and vascular surgeries, to the intricately complex, including the use of the left ventricular assist device and organ transplants. This practical and comprehensive text blends theevidence-based standards of care with cutting edge advances in the field, while also providing the reader with a peek into innovations on the horizon.…

Taschenbuch. Condición: Neu. Neuware - The World Health Organization stated that approximately two-thirds of the world's population lacks adequate access to medical imaging. The scarcity of imaging services in developing regions contributes to a widening disparity of health care and limits global public health programs that require imaging. Radiology is an important component of many global health programs, including those that address tuberculosis, AIDS-related disease, trauma, occupational and environmental exposures, breast cancer screening, and maternal-infant health care. There is a growing need for medical imaging in global health efforts and humanitarian outreach, particularly as an increasing number of academic, government, and non-governmental organizations expand delivery of health care to disadvantaged people worldwide. To systematically deploy clinical imaging services to low-resource settings requires contributions from a variety of disciplines such as clinical radiology, epidemiology, public health, finance, radiation physics, information technology, engineering, and others. This book will review critical concepts for those interested in managing, establishing, or participating in a medical imaging program for resource-limited environments and diverse cross-cultural contexts undergoing imaging technology adaptation.…

Taschenbuch. Condición: Neu. Neuware -Protein Design: Method and Applications, Second Editionexpands upon the previous edition with current, detailed ideas on how to approach a potential protein design project. With new chapters onmetals as structure-forming elements and functional sites, the design and characterization of fluorinated proteins, top-down symmetric deconstruction and the design of protein libraries and novel or repurposed enzymes.Written in the highly successfulMethods in Molecular Biologyseries format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Thorough and intuitive,Protein Design: Method and Applications, Second Editionprovides a number of practical protocols and instructive reviews to aid in the creation of new experiments.Humana Press in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 292 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - Having indicators to assess the effect of zootechnical, sanitary, economic or political intervention or the impact of environmental risks makes it possible to draw up strategies for improving domestic animal populations. This handbook is a compilation of the main concepts relating to the definition and calculation of demographic rates for largely non-intensive tropical animal farms. It is intended to be educational, and should help students, technicians, engineers, researchers and development staff to understand the definitions and formulas encountered in the literature more clearly and make them more self-sufficient in terms of analyses.…

Taschenbuch. Condición: Neu. Neuware - This book provides the most recent findings and knowledge in advanced diagnostics technology, covering a wide spectrum including brain activity analysis, breast and lung cancer detection, echocardiography, computer aided skeletal assessment to mitochondrial biology imaging at the cellular level. The authors explored magneto acoustic approaches and tissue elasticity imaging for the purpose of breast cancer detection. Perspectives in fetal echocardiography from an image processing angle are included. Diagnostic imaging in the field of mitochondrial diseases as well as the use of Computer-Aided System (CAD) are also discussed in the book. This book will be useful for students, lecturers or professional researchers in the field of biomedical sciences and image processing.…

Taschenbuch. Condición: Neu. Neuware - This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others.Written by world-renowned scientists in the field, Neural Stem Cells in Development, Adulthood and Disease presents cutting-edge studies of interest to both established neurogenesis researchers and readers with general interests in nervous system science. It is an authoritative addition to the Stem Cell Biology and Regenerative Medicine series.…

Taschenbuch. Condición: Neu. Neuware - The aim of this book is to offer a river-basin management plan which is directly implementable and consistent with the European Union -Water Framework Directive (EU WFD).The contributors, who are leading world experts in their respective fields, develop an integrated water resources management plan for the Asopos river basin in Greece which is economically efficient, socially equitable and environmentally sustainable. The program offers explicit technical and investment solutions, socioeconomic and legal instruments and recommendations for institutional restructuring. The introductory chapter describes the water situation in Greece and assesses the potential of timely implementation of the EU WFD. Special emphasis is given to the cost-recovery principle. Chapter 2 introduces the case study area highlighting the particular pressures and impacts as well as the environmental functions and values of Asopos River and Oropos Lagoon. Chapters 3 and 4 focus on the economic characterisation of Asopos River Basin in order to identify the economic sectors and social groups that will bear the cost and benefits of the implementation of the EU WFD. In particular, Chapter 3 presents the main water uses and pricing for water supply in the industrial and the agricultural sectors. Chapter 4 completes the baseline appraisal, presenting the details of water use by the residential and touristic sectors. The following chapters assess valuation and decision-making tools from a range of perspectives, including agricultural needs, valuing the impacts of industrial activity, the costs and benefits of environmental preservation and management. The water resources management plan is presented in Chapter 9; the concluding chapter offers recommendations on institutional changes and presents the lessons learned as resources applicable to other river basins in Greece and elsewhere. The book applies state-of-the art market and non-market valuation methods to estimate water demands in the residential, industrial, agricultural, tourism, environmental and health sectors and to balance these, over time and space, with water supply. Given the well-known challenge of managing natural resources in a way that maximizes and sustains social welfare, this book will provide an invaluable point of reference for applied researchers and policy makers working in water resources management.…

Taschenbuch. Condición: Neu. Neuware - For many years, the authors have investigated the adaptive role of heat shock proteins (HSPs) in different animals, including the representatives of homothermic and poikilothermic organisms that inhabit regions with contrasting thermal conditions. This book will summarize the data accumulated in the course of these studies and describe the general molecular mechanisms underlying the adaptation of various organisms to aggressive environments. We also concentrate on different evolutionary trends characteristic for HSP systems in the course of adaptation to fluctuating environmental conditions. In addition, we describe the peculiarities in the regulatory regions of heat shock genes necessary for fine tuning of these systems providing the adaptation to adverse conditions. Special emphasis is given to the role of mobile elements in the evolution and functioning of various groups of HSP genes. The book combines the results of field studies and laboratory analysis of stress genes systems.…

Taschenbuch. Condición: Neu. Neuware - The first OZCOTS conference in 1998 was inspired by papers contributed by Australians to the 5th International Conference on Teaching Statistics. In 2008, as part of the program of one of the first National Senior Teaching Fellowships, the 6 th OZCOTS was held in conjunction with the Australian Statistical Conference, with Fellowship keynotes and contributed papers, optional refereeing and proceedings. This venture was so successful that the 7 th and 8 th OZCOTS were similarly run, conjoined with Australian Statistical Conferences in 2010 and 2012. Authors of papers from these OZCOTS conferences were invited to develop chapters for refereeing and inclusion in this volume. There are sections on keynote topics, undergraduate curriculum and learning, professional development, postgraduate learning, and papers from OZCOTS 2012. Because OZCOTS aim to unite statisticians and statistics educators, the approaches this volume takes are immediately relevant to all who have a vested interest in good teaching practices. Globally, statistics as a discipline, statistical pedagogy and statistics in academia and industry are all critically important to the modern information society. This volume addresses these roles within the wider society as well as questions that are specific to the discipline itself. Other chapters share research on learning and teaching statistics in interdisciplinary work and student preparation for futures in academia, government and industry.…

Taschenbuch. Condición: Neu. Neuware - This book discusses recent developments and contemporary research in mathematics, statistics and their applications in computing. All contributing authors are eminent academicians, scientists, researchers and scholars in their respective fields, hailing from around the world. The conference has emerged as a powerful forum, offering researchers a venue to discuss, interact and collaborate and stimulating the advancement of mathematics and its applications in computer science. The book will allow aspiring researchers to update their knowledge of cryptography, algebra, frame theory, optimizations, stochastic processes, compressive sensing, functional analysis, complex variables, etc. Educating future consumers, users, producers, developers and researchers in mathematics and computing is a challenging task and essential to the development of modern society. Hence, mathematics and its applications in computer science are of vital importance to a broad range of communities, including mathematicians and computing professionals across different educational levels and disciplines.…

Taschenbuch. Condición: Neu. Neuware - The book departs from the approach of related titles by focusing on describing and reflecting upon the notion of seamless learning with regard to salient characteristics of learner mobility and bridging of learning experiences across learning spaces. It is the first such work that is solely dedicated to research on and the practice of seamless learning, uniquely combining interpretations, visions, and past research on and practices in seamless learning from diversified perspectives. The book also strikes a good balance between theoretical and practical perspectivess, going beyond a collection of reports on specific research projects. Instead of thick descriptions of research processes and findings, readers will find significant insights and food for thought intended to inspire further advances in the research on and practice of seamless learning.…

Taschenbuch. Condición: Neu. Neuware -Kindliches Verhalten mit neuen Augen sehen - verständlich, praxisbezogen und umsetzbarDr. Jean Ayres' Theorie der Sensorischen Integration hat in den letzten 30 Jahren die Welt erobert und unser Verständnis der kindlichen Entwicklung entscheidend verändert. Jean Ayres ist es gelungen, die Erkenntnisse ihrer langjährigen wissenschaftlichen Arbeit für alle, die mit Kindern zu tun haben, verständlich darzustellen. Sie zeigt, wie die Verarbeitung von Sinnesinformationen die kindliche Entwicklung grundlegend beeinflusst und wie sich Störungen dieses Prozesses auf das Lernen, die Gefühlswelt, das Verhalten und die sozialen Beziehungen auswirken.Neu:- Didaktisch wesentlich erweitert, komplett überarbeitetund farbig gestaltet- Besonders verständlich durch Fallgeschichten und Beispiele- Zahlreiche Abbildungen verdeutlichen neurologischeZusammenhänge- Checklisten und zahlreiche Tipps für Eltern, PädagogenundTherapeutenPlus: Kommentare von Experten aus heutiger Sicht zurSensorischen IntegrationEin Standardwerk zur kindlichen Entwicklung, das einen Stammplatzin Kindergärten, Arztpraxen, Therapieabteilungen und im Bücherregaljeder Familie mit Kindern - mit und ohne Wahrnehmungsstörungen -verdient. 304 pp. Deutsch.…

Taschenbuch. Condición: Neu. Neuware -Kindliches Verhalten mit neuen Augen sehen - verständlich, praxisbezogen und umsetzbarDr. Jean Ayres' Theorie der Sensorischen Integration hat in den letzten 30 Jahren die Welt erobert und unser Verständnis der kindlichen Entwicklung entscheidend verändert. Jean Ayres ist es gelungen, die Erkenntnisse ihrer langjährigen wissenschaftlichen Arbeit für alle, die mit Kindern zu tun haben, verständlich darzustellen. Sie zeigt, wie die Verarbeitung von Sinnesinformationen die kindliche Entwicklung grundlegend beeinflusst und wie sich Störungen dieses Prozesses auf das Lernen, die Gefühlswelt, das Verhalten und die sozialen Beziehungen auswirken.Neu:- Didaktisch wesentlich erweitert, komplett überarbeitetund farbig gestaltet- Besonders verständlich durch Fallgeschichten und Beispiele- Zahlreiche Abbildungen verdeutlichen neurologischeZusammenhänge- Checklisten und zahlreiche Tipps für Eltern, PädagogenundTherapeutenPlus: Kommentare von Experten aus heutiger Sicht zurSensorischen IntegrationEin Standardwerk zur kindlichen Entwicklung, das einen Stammplatzin Kindergärten, Arztpraxen, Therapieabteilungen und im Bücherregaljeder Familie mit Kindern - mit und ohne Wahrnehmungsstörungen -verdient. 304 pp. Deutsch.…

Taschenbuch. Condición: Neu. Neuware - This important volume provides a holistic understanding of the cultural, psychological, neurological and biological elements involved in human facial expressions and of computational models in the analyses of expressions. It includes methodological and technical discussions by leading scholars across the world on the subject. Automated and manual analysis of facial expressions, involving cultural, gender, age and other variables, is a growing and important area of research with important implications for cross-cultural interaction and communication of emotion, including security and clinical studies. This volume also provides a broad framework for the understanding of facial expressions of emotion with inputs drawn from the behavioural sciences, computational sciences and neurosciences.…

Taschenbuch. Condición: Neu. Neuware -Achieving operational excellence isachallenge for the pharmaceutical industry, with many companies setting successful examples time and again. This bookpresents such leading practices for managing operational excellence throughout the pharmaceutical industry. Based on the St.Gallen OPEX Model the authors describe the current status of OPEX and the future challenges that have to be dealt with. The ample theoretical background is complemented hand-in-hand by case studies contributed by authors from leading pharmaceutical companies.¿. …

Taschenbuch. Condición: Neu. Neuware -There is a tremendous interest among researchers for the development of virtual, augmented reality and games technologies due to their widespread applications in medicine and healthcare. To date the major applications of these technologies include medical simulation, telemedicine, medical and healthcare training, pain control, visualisation aid for surgery, rehabilitation in cases such as stroke, phobia and trauma therapies. Many recent studies have identified the benefits of using Virtual Reality, Augmented Reality or serious games in a variety of medical applications.This research volume on Virtual, Augmented Reality and Serious Games for Healthcare 1 offers an insightful introduction to the theories, development and applications of virtual, augmented reality and digital games technologies in medical and clinical settings and healthcare in general. It is divided into six sections: section one presents a selection of applications in medical education and healthcare management; Section two relates to the nursing training, health literacy and healthy behaviour; Section three presents the applications of Virtual Reality in neuropsychology; Section four includes a number of applications in motor rehabilitation; Section five aimed at therapeutic games for various diseases; and the final section presents the applications of Virtual Reality in healing and restoration.This book is directed to the healthcare professionals, scientists, researchers, professors and the students who wish to explore the applications of virtual, augmented reality and serious games in healthcare further.…

Taschenbuch. Condición: Neu. Neuware - Squamous cell cancers of the head and neck (SCCHN), also known as head and neck cancers (HNC) encompass malignancies of the oral cavity, larynx, nasopharynx and pharynx, and are diagnosed in over 500,000 patients worldwide each year, accounting for 5% of all malignancies. In the past several years, there have been significant developments in understanding of HNC. It is now recognized that although alcohol and tobacco use has represented the likely predominant cause of SCCHN, the incidence of a second class of SCCHN related to oncogenic human papillomavirus (HPV) infection is increasing, with a four-fold increase in the past 2 decades, and now thought to represent up to 30% of cases. The first effective target for SCCHN, the EGFR-targeting antibody cetuximab, was approved as recently as in 2006; since then, a growing body of research has identified additional signaling pathways as important in disease pathogenesis, and in resistance to treatment. Proteins such as c-Met, Src, and HER2 are emerging as new therapeutic targets, with a considerable ferment in the clinical trial community. As a capstone of research progress, 2011 marked the first reports of high throughput sequencing of SCCHN tumors, with these efforts identifying unexpected players such as Notch as frequent subject of mutation, spawning new hypotheses for future research. This book will be of interest to researchers who are interested in better understanding the biology of head and neck cancers, with the goals of better designing therapies, identifying risk factors, or investigating the molecular basis of the disease.…

Taschenbuch. Condición: Neu. Neuware -This important volume provides a holistic understanding of the cultural, psychological, neurological and biological elements involved in human facial expressions and of computational models in the analyses of expressions. It includes methodological and technical discussions by leading scholars across the world on the subject. Automated and manual analysis of facial expressions, involving cultural, gender, age and other variables, is a growing and important area of research with important implications for cross-cultural interaction and communication of emotion, including security and clinical studies. This volume also provides a broad framework for the understanding of facial expressions of emotion with inputs drawn from the behavioural sciences, computational sciences and neurosciences. 300 pp. Englisch.…

Buch. Condición: Neu. Neuware -Thoroughly revised and extensively expanded, this encyclopedic, highly acclaimed title addresses all aspects of the etiology, pathogenesis, diagnosis, initial treatment and long-term management of all varieties of thyroid cancer. Expertly edited by Drs. Leonard Wartofsky and Douglas Van Nostrand, this gold standard reference is divided into 11 Parts: General Considerations on Thyroid Cancer; General Considerations on Nuclear Medicine; the Thyroid Nodule; Well-Differentiated Thyroid Cancer; Variants of Thyroid Cancer, Undifferentiated Tumors: Medullary Thyroid Carcinoma; Undifferentiated Tumors: Thyroid Lymphoma; Undifferentiated Tumors: Anaplastic Thyroid Cancer; New Frontiers and Future Directions; and Additional Resources. With exceptional breadth and depth, the book includes chapters dedicated to isotopes, isotope uptake and scanning procedures such as SPECT/CT, radioiodine ablation (with or without recombinant human TSH), stunning, dosimetry (with or without recombinant human TSH), Octreotide and FDG-PET scanning and other alternative imaging modalities. There is a valuable reference atlas of scan images and illustrations, and a scholarly summary of the side effects of radioiodine and how to avoid or minimize adverse effects of treatment. In addition to an updated section on ultrasonography of the thyroid gland, new sections have been added, including ones on ultrasonography of cervical lymph nodes and imaging for thyroid cancer employing computerized tomography (CT), positron emission tomography (PET) and magnetic resonance imaging (MRI). An indispensable reference source with chapters written by the field's leading authoritative experts, Thyroid Cancer: A Comprehensive Guide to Clinical Management, Third Edition, will be of great interest to not only pathologists, endocrine surgeons, endocrinologists, nuclear medicine physicians, and oncologists but all clinicians with an interest in thyroid cancer. 1049 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - Cutting edge technologies can propel a simple finding in basic science to a concept that can be of immense value to the society. While applying novel techniques to unravel the mysteries of biological processes, an offshoot of applied branch emerged. This field, which is now widely referred to as Translational Research utilizes basic science findings and translates these findings into innovative concepts for the benefit of mankind. This branch of science has evolved into a multidisciplinary juggernaut encompassing all known fields of science as varied as biomedicine, environment, law, economics, sociology, etc. With the ever increasing interest in this branch and the dreams and aspirations that this field can bring, basic science researchers are now taking a bold step into this new realm, merging different fields of knowledge to come up with novel inventions. This book 'Translational research in environmental and occupational stress' provides and insight into the research that led to discoveries, inventions and development of novel technologies which will have a tremendous impact on the future of mankind. …

Taschenbuch. Condición: Neu. Neuware - DNA and RNA fractions can be isolated from a variety of body fluids including whole blood, serum, plasma, urine, saliva and cerebrospinal fluid from both patients and healthy individuals. Such isolates can be exploited in the early detection of clinical disorders, stratification of patients for treatment, treatment monitoring and clinical follow-up. In addition, the use in fetal medicine allows the early detection of fetal sex, Rh factor and aneuploid disorders as well as following both fetal and premature born infant development. This volume is intended as a primer for those who are interested in entering the field of circulating nucleic acids.The areas covered in this volume include: Background and general biology of circulating nucleic acids Methodology Applications of circulating nucleic acids Quality Assurance Ethics.…