humana jun 2013 (146 resultados)

Taschenbuch. Condición: Neu. Neuware - Regulation of malignant cell growth by the immune system has been extensively studied by cancer researchers hoping to develop immuno therapeutic approaches to cancer management. For years these studies revolved around the recognition and destruction of tumors by cytotox. ic immune effector cells. Recently, however, attention has focused on the leukolysins, which are the soluble cytotoxic molecules secreted by activated leukocytes, because of their anticancer activities. The purpose of this book is to give an overview of the ieukolysins, with emphasis on their ability to regulate malignant cell growth. Because this is such a new field in cancer research, there remains some confusion regarding the tenninology of. and biological activity ascribed to, the different leukolysins. Therefore, we sought to present a comprehensive review of the leukolysins currently under intensive study and to compare and contrast their biological activities in an attempt to clarify the nature of these diverse biological species. This book is intended for both immunologists conducting basic research and clinical oncologists, since it reviews not only the clinical applications of the leukolysins, but presents a current update on those leukolysins that are in early developmental stages of research and could enter into clinical trials in a few years. The introduction gives an overview of the status of research on the leukolysins. In the first section, the biological activities and biochemical characteristics of the leukolysins are presented. The lymphokines.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present volume is based on the proceedings of the 9th INFN ELOISATRON Project workshop held at the Ettore Majorana Centre for Scien tific Culture, Erice-Trapani, Italy, in the period July 15-26, 1989. The topic of this workshop was: Higgs Particles - Physics Issues and Experimental Searches in High Energy Collisions and it was attended by over forty participants. The concept of Higgs mechanism, like most other scientific ideas, evolved over several years, with many independent and important contribu tions in the sixtees to which Peter Higgs has referred in his historical account in these proceedings. However, it was not until 1967, paraphra sing Weinberg, that 'the right ideas were applied to the right problem'! Higgs mechanism, i.e. spontaneous breaking of local gauge symmetries with scalar particles becoming the longitudinal degrees of freedom of {other wise) massless vector bosons and hence making them massive, is now an integral part of the standard {Glashow-Salam Weinberg) theory of electro weak interactions. Fortunately for us, the structure of the standard theory prevents at least one scalar field from being transformed away. This is the Higgs particle in the standard theory - whose physics and search strategies are the subject of this workshop. 516 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'lbere is much discussion today concerning 'Bioengineering' (or 'Biomedical Engineering'). It is not exactly clear what these names signify, particularly in chemical engineering. Some have suggested retreading the old war horse 'Biochemical Engineering' (or was it 'Biomedical Chemical Engineering). In an effort to demonstrate the on-going activities of chemical engineers in the life science area, we accepted the invitation of the Industrial and Engineering Division of the American Chemical Society to organize the 33rd Annual Chemical Engineering Symposium. We decided to call the symposium, Chemical Engineering in Medicine and Biology, and hence avoided the problem of having to decide which 'bio' prefix to use. Many chemical engineers in the academic and industrial world were contacted. From these contacts and a good deal of publicity arose the Symposium. The two-day meeting was held at the University of Cincinnati in the Losantiville Room of the Student Union Building on October 20-21, 1966. Twenty-one papers were presented on topics relating chemical engineering to medicine and biology. Tile papers were representation al of the scope of the activities across the country with presenters coming from Washington, California, Massachusetts, New York, South Carolina, Wisconsin, Iowa, Pennsylvania, Michigan, Indiana and Texas. TOpics ranged over blood flow properties, diffusion in blood phenomena, ix INTRODUCTION X mass transfer in the eye, artificial kidney analysis, separation of bacteria by ion exchange, mathematical modeling of drug distribution, carbon dioxide respiration, photosynthetic kinetics, water in frozen tissues, electrophoretic separation of proteins, and outerspace re search on life support systems. 672 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The theory of almost-periodic functions with complex values, created by H. Bohr [1] in his two classical papers published in Acta Mathematica in 1925 and 1926, has been developed by many authors and has had note worthy applications: we recall the works of Weyl, De la Vallee Poussin, Bochner, Stepanov, Wiener, Besicovic, Favard, Delsarte, Maak, Bogoliu bov, Levitan. This subject has been widely treated in the monographs by Bohr [2], Favard [1], Besicovic [1], Maak [1], Levitan [1], Cinquini [1], Corduneanu [1], [2]. An important class of almost-periodic functions was studied at the beginning of the century by Bohl and Esclangon. Bohr's theory has been extended by Muckenhoupt [1] in a particular case and, subsequently, by Bochner [1] and by Bochner and Von Neumann [1] to very general abstract spaces. The extension to Banach spaces is, in particular, of great interest, in view of the fundamental importance of these spaces in theory and application. 196 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Experimental Hematology Today - 1988 presents the latest results of research reflecting the diverse interests of basic and clinical hematologists. The major areas explored are hematopoietic regulation by cytokines; hematopoietic cellular growth regulation, with emphasis on the interaction of stromal with hematopoietic stem and progenitor cells; granulopoietic regulators; gene transfers into hematopoietic progenitor cells; leukemogenesis; and bone marrow transplantation. All chapters report on research or clinical findings of the past year. 204 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The purpose of this book is to give an introduction to the Laplace transform on the undergraduate level. The material is drawn from notes for a course taught by the author at the Milwaukee School of Engineering. Based on classroom experience, an attempt has been made to (1) keep the proofs short, (2) introduce applications as soon as possible, (3) concentrate on problems that are difficult to handle by the older classical methods, and (4) emphasize periodic phenomena. To make it possible to offer the course early in the curriculum (after differential equations), no knowledge of complex variable theory is assumed. However, since a thorough study of Laplace. transforms requires at least the rudiments of this theory, Chapter 3 includes a brief sketch of complex variables, with many of the details presented in Appendix A. This plan permits an introduction of the complex inversion formula, followed by additional applications. The author has found that a course taught three hours a week for a quarter can be based on the material in Chapters 1, 2, and 5 and the first three sections of Chapter 7. If additional time is available (e.g., four quarter-hours or three semester-hours), the whole book can be covered easily. The author is indebted to the students at the Milwaukee School of Engineering for their many helpful comments and criticisms. 216 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is on dependence concepts and general methods for dependence testing. Here, dependence means data dependence and the tests are compile-time tests. We felt the time was ripe to create a solid theory of the subject, to provide the research community with a uniform conceptual framework in which things fit together nicely. How successful we have been in meeting these goals, of course, remains to be seen. We do not try to include all the minute details that are known, nor do we deal with clever tricks that all good programmers would want to use. We do try to convince the reader that there is a mathematical basis consisting of theories of bounds of linear functions and linear diophantine equations, that levels and direction vectors are concepts that arise rather natu rally, that different dependence tests are really special cases of some general tests, and so on. Some mathematical maturity is needed for a good understand ing of the book: mainly calculus and linear algebra. We have cov ered diophantine equations rather thoroughly and given a descrip of some matrix theory ideas that are not very widely known. tion A reader familiar with linear programming would quickly recog nize several concepts. We have learned a great deal from the works of M. Wolfe, and K. Kennedy and R. Allen. Wolfe's Ph. D. thesis at the University of Illinois and Kennedy & Allen's paper on vectorization of Fortran programs are still very useful sources on this subject. 168 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Suppose an accountant discovers evidence of shady practices while ex amining the books of a client. What should he or she do Accountants have a professional obligation to respect the confidentiality of their cli ents' accounts. But, as an ordinary citizen, our accountant may feel that the authorities ought to be informed. Suppose a physician discov ers that a patient, a bus driver, has a weak heart. If the patient contin ues bus driving even after being informed of the heart condition, should the physician inform the driver's company Respect for patient confidentiality would say, no. But what if the driver should suffer a heart attack while on duty, causing an accident in which people are killed or seriously injured Would the doctor bear some responsibility for these consequences Special obligations, such as those of confidentiality, apply to any one in business or the professions. These obligations articulate, at least in part, what it is for someone to be, say, an accountant or a physician. Since these obligations are special, they raise a real possibility of con flict with the moral principles we usually accept outside of these spe cial relationships in business and the professions. These conflicts may become more accentuated for a professional who is also a corporate employee-a corporate attorney, an engineer working for a construction company, a nurse working as an employee of a hospital. 348 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As Chairmen of the Electrochemistry and Molten Salts Discussion Groups of the Chemical Society, it gave us great pleasure to welcome the confer ence Highly Concentrated Aqueous Solutions and Molten Salts, which our Groups cosponsored, at St. John's College, Oxford in July 1978. During the meeting the editors of the present volume, and those giving lectures, came to the conclusion that the verbal presentations deserved to be expanded and to be more widely disseminated in a permanent form. Thus the articles which appear in this volume were commissioned and prepared. A greater exchange of information between aqueous chemists and those concerned with molten salts is to be welcomed and to this end the present volume aims to focus attention on the borderline areas between the two in an attempt to facilitate a wider awareness of the concepts and methods appropriate to the respective specialities. Similarly, and parti cularly in the electrochemical field, a greater exchange of information be tween the academic and industrial practitioners of the subject is desirable. T!1e problems involved are not trivial but when the interactions in these largely (but not wholly) ionic liquids are better understood, this wiii surely be to the benefit of all concerned with solution chemistry. Douglas Inman, Imperial College Chairman, Electrochemistry Group David Kerridge, University of Southampton Chairman, Molten Salts Discussion Group v Preface A number of recent events led to the appearance of this text at this particu lar time. 464 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is about human behavior and, more particularly, about a class of human behaviors-those behaviors by people that have themselves as the object of their behaviors. These self-referent behaviors are social in nature in the sense that in large measure, they are the outcomes of pervasive social processes and are themselves major influences on social outcomes. As such, self-referent behaviors have the potential to be sig nificant organizing constructs in the study of the broader field of social psychology. In any case, they are regarded here as of intrinsic interest and are the focus of this volume. Four broad categories of self-referent behaviors are considered with regard to their social bases and conse quences as these are revealed in the social psychological and sociological literature. With appropriate discriminations made within each group ing, the four categories are: self-conceiving, self-evaluating, self-feeling, and self-protective-self-enhancing responses. Following a consideration of the social antecedents and consequences of each category of self referent behaviors, I present a final summary statement that outlines a theoretical model of the additive and interactive social influences on and consequences of the mutually influential self-referent behaviors. The outline of the theoretical model reflects my synthesis of the apparently relevant theoretical and empirical literature and is intended to function as a framework for the orderly incorporation of new theoretical asser tions and more or less apparently relevant empirical associations. 224 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The present volume contains a large variety of treatment approaches to the long-term rehabilitation of the alcoholic, ranging from the biological to the physiological to the psychological to the social. The multiplicity of proposed therapies, each of which has its strong proponents, suggests that alcoholism is either a complex medical-social disease syndrome requiring a multipronged treatment approach or a very simple illness for which we have not yet dis covered the remedy. The latter may, indeed, be true, but we cannot use what we do not know and must use what we do know. We do, however, have the obligation to be responsible in our treatment, to provide the best that is known at this time, and to be discriminating in our prescription of appropriate treat ment for individual patients. If there is one conclusion we would like to offer in our preface, it is that alcoholics constitute a markedly heterogeneous popula tion with widely disparate needs, for whom, at least at our present level of knowledge, a broad spectrum of treatment modalities is necessary. If this is true, then probably most of this book has validity. With this volume on the treatment and rehabilitation of the chronic alco holic, we bring to completion our five-volume series, The Biology of Alcoholism. As the title of the present volume indicates, we have departed from our original intention to deal solely with biological aspects of the syndrome and have attempted rather to produce a more comprehensive work. 660 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book discusses contemporary features of ject, creating, therefore, a lacuna the could be diagnosis of endocrine diseases using the filled by this project. radiologic technique of percutaneous venous This book is intended to be a practical guide blood sampling for hormone assay. A compre for vascular and interventional radiologists, in hensive survey of the field is provided by the ternists, surgeons, endocrinologists, and other contributing authors, who have considerable physicians who care for patients with endocrine expertise in the subject. Some have published diseases. The intention is to provide a practical several articles in the literature; others have text covering anatomical data, clinical prob extensive clinical experience. lems related to the diagnosis of the endocrine The approach to many of the endocrine dis diseases, patient preparation for the sampling, eases has been markedly improved ~uring the blood sampling techniques, sample manipula last two decades because of selective venous tion and storage, laboratory data, and clinical blood sampling, not only in the diagnosis of the significance of the hormone sampling and condition but especially in the precise localiza assay. tion of the hormone-producing lesion and its clinical significance. Scattered informationbn venous blood sam pling is available in the literature, but there is Renan Uftacker no comprehensive text dealing with the sub- Reingard Sorensen Contents Preface v Contributors xi 1 Selective Venous Sampling for the Differential Diagnosis of Female Hyperandrogenemia 1 Lathar Moltz and Reingard Sorensen Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 Diagnostic Procedures . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 Indications . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 Anatomy and Anatomical Variations. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 200 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Opening Address.- Prospects for High-Energy Particle Physics and Future Colliders.- Accelerator Amplitude and Phase Control.- RF Structures for Linear Accelerators.- RF Driven Linear Colliders.- Frequency Scaling and Gyroklystron Sources for Linear Colliders with SLAC-Type Linac Structures.- RF System of a Synchrotron for Protons and Heavy Ions.- Basic Features of Superconducting RF Cavities.- One Dimensional Model for the Interaction of a High Charged Bunched Beam with a Superconducting Cavity.- RF-Structures: A Survey.- Superconducting Radio Frequency Cavities for Accelerators.- RF System Design for Control of Heavy Beam Loading in Circular Machines.- Components for High-Power RF Systems in Modern Accelerators.- Radio Frequency Systems for Present and Future Accelerators.- RF Cavity Primer for Cyclic Proton Accelerators.- Concluding Remarks.- Participants. 376 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In his book, Global Purchasing: Reaching/or the World, Victor Pooler has stripped the supposed maze of complexity and misunderstanding from international com merce. This book provides extensive background materials for both the purchas ing/materials practitioner and the academic who wishes to use it as a text. The author's extensive international experience lends credibility. Of special interest are the global supplier sourcing strategies. The basics of good offshore buying are universal and of great importance to America. There is a need to analyze and investigate global supplier capabilities. On-the-job buyers need global techniques they can apply. Import prices are destined to rise, and it will take better buying strategies to deal with the multi-bil lions of dollars of purchases made outside the United States. This book brings together in great detail the full spectrum of benefits available to the global buyer. He or she has an opportunity to view the global economy and understand its financial implications. It contains a working knowledge of import regulations, customs tariffs,_ currency translation issues, hedging, cultural aware ness applied to negotiations, and logistics-all covered in detail. During the 1990s, the world of the global buyer will become a reality. Long neglected is the American buyer's study of other cultures and the techniques of dealing with suppliers outside our national boundaries. This book goes a long way in filling that knowledge void. 288 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the past ten years, the problem of child abuse has been the subject of increased attention both in the professional community and among the general public. The reasons for this widespread recogni tion are clear. First, professionals of many disciplines deal with child abusive families and do so in a variety of ways: Physicians, hospital staff, and teachers are often the first to assess a child as the victim of abuse; social workers and child-protective personnel investigate cases of suspected abuse; court and legal authorities make determinations concerning the needs of an abused child; and mental health profes sionals, including psychologists, social workers, and family coun selors, often have responsibility for treating abusive families. Few clinical problems have received this kind of widespread interdisci plinary recognition and, given the nature and seriousness of child abusive behavior, few problems receive such intensive attention within each profession's literature. A second factor responsible for increased study of child abuse is the fact that violence directed toward children is probably the most extreme form of family dysfunction seen by counselors, therapists, and other practitioners. While other types of child-management and anger-control problems occur far more frequently, the consequences of child-abusive behavior are much more serious than the conse quences of other problems seen in child or family clinics. It has been v vi PREFACE estimated that as many as 550,000 children are the targets of parental abuse in the country each year (Helfer & Kemper, 1976). 236 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Presents and addresses key space law and policy issues for the benefit of wider informed audiences that wish to acquaint themselves with the fundamentals of the space law field. This brief analyzes in a concise manner the combined influence of space law and policy on international space activities. Read in conjunction with the other books in the Springer 'Space Development' series, it supports a broader understanding of the business, economics, engineering, legal, and procedural aspects of space activities. This book will also give the casual reader as well as experts in the field insight on present and future space law and policy trends, challenges and opportunities. 128 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The completion of this volume would not have been possible without the generous and dedicated help of numerous people. The book had its genesis in a conference held at Cornell University in the fall of 1990 that was organized by Dudley Poston, Paul Eberts, and Michael Hannan, all professors at the time at Cornell. With the very generous financial assistance of David Call, then the dean of Cornell's College of Agriculture and Life Sciences, Poston, Eberts, and Hannan put together a two-day conference oflectures and papers by human ecologists from Cornell University and elsewhere. The conference focused on sociological human ecology and celebrated the fortieth anniversary of the publication of Amos Hawley's Human Ecology (Ronald Press 1950). Professor Hawley was the keynote speaker at the conference. Many of the authors of the chapters in this volume presented earlier versions at the Cornell conference in 1990. Cornell's Departments of Rural Sociology and Sociology also contrib uted financial assistance; however, without Dean Call's very generous support, the conference would not have been possible. A few months after the conference, Poston and Michael Micklin discussed the possibility of asking the various authors of the Cornell conference papers to revise them for publication in a volume on sociological human ecology. Many opted to do so, but others did not because of time and other kinds of commitments and constraints.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 392 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This book is on dependence concepts and general methods for dependence testing. Here, dependence means data dependence and the tests are compile-time tests. We felt the time was ripe to create a solid theory of the subject, to provide the research community with a uniform conceptual framework in which things fit together nicely. How successful we have been in meeting these goals, of course, remains to be seen. We do not try to include all the minute details that are known, nor do we deal with clever tricks that all good programmers would want to use. We do try to convince the reader that there is a mathematical basis consisting of theories of bounds of linear functions and linear diophantine equations, that levels and direction vectors are concepts that arise rather natu rally, that different dependence tests are really special cases of some general tests, and so on. Some mathematical maturity is needed for a good understand ing of the book: mainly calculus and linear algebra. We have cov ered diophantine equations rather thoroughly and given a descrip of some matrix theory ideas that are not very widely known. tion A reader familiar with linear programming would quickly recog nize several concepts. We have learned a great deal from the works of M. Wolfe, and K. Kennedy and R. Allen. Wolfe's Ph. D. thesis at the University of Illinois and Kennedy & Allen's paper on vectorization of Fortran programs are still very useful sources on this subject.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 168 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Sexually Transmitted Diseases: A Guide for Primary Care, second edition, covers the diagnosis and treatment of STDs and other information critical to patient care and reflects the last five years of significant changes in information about STDs. Updated to reflect the 2010 Center for Disease Control Guidelines on the Treatment of STDs, this book also contains new information about:the epidemiology of herpes virus infectionsexpedited partner therapychanges in recommendations for HPV vaccination for menchanges in resistance patterns for antimicrobial therapy for gonorrhea and chlamydiatreatment recommendations for bacterial vaginosistreatment recommendations for genital wartsIn order to better meet clinician needs, the book has been streamlined to quickly convey critical, evidence-based information. Whether seeking information about particular conditions (including HPV, herpes, syphilis, trichomoniasis, HIV and AIDS, and others) or related patient issues (such as STD exposure evaluation and evaluation of sexual assault), Sexually Transmitted Diseases, second edition, contains the knowledge doctors need in a friendly, to-the-point format.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 200 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -There are many unanswered questions regarding the molecular nature of antibodies, components of complement, and other substances which participate in the immune response. The list of substances which need to be analyzed chemically is increasing. Plasma cell products, of course, have long been of great interest because the most prevalent ones are immunoglobulins. Other cell types, however, are the source of the broad spectrum of additional substances which classically fall into the sanctum of the molecular immunologist. It is these substances, and especially those more recently discovered, which are responsible for the broadening investigative interests of immunologists. In this volume we have provided you with descriptions of research being done with immunoglobulins and with complement. Additionally, we have in cluded two reports that deal with molecules which are among the more recent acquisitions of the molecular immunologist. The components of complement are known to react in a cascading manner which results in the lysis of cellular antigens. The first step in the classical pathway requires the activation of CI by the antibody-antigen aggregates. This volume of Contemporary Topics in Molecular Immunology begins with the report of Reid and Porter which describes their investigation of the mechanism of activation of C I. Their descriptions of C I q and of the reaction of C I with immunoglobulins are especially intriguing. It is clearly apparent from their report that activation of the components of complement is a complex phenome non.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 260 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -An Advanced Study Institute on Radiative Processes in Discharge Plasmas was held at the Atholl Palace Hotel, Pitlochry, Perthshire, Scotland, June 23 through July 5, 1985. This publication is the Pro ceedings from that Institute. The Institute was attended by eighty-five Participants and Lecturers representing the United States, Canada, France, West Germany, Greece, The Netherlands, Portugal, Turkey, the United Kingdom, and Switzerland. A distinguished faculty of eighteen Lecturers was assembled and the topical program organized with the assistance of an Advisory Committee composed of: Dr. John Waymouth, USA; Dr. Timm Teich, Switzerland; Dr. Arthur Phelps, USA; Dr. Nicol Peacock, England; Professor Erich Kunhardt, USA; Dr. Anthony Hyder, USA; and Dr. Arthur Guenther, USA. The underlying theme and objective of the Institute was the enhance ment of scientific communication and exchange among academic, industrial, and national laboratory groups having a common concern for radiative processes in discharge plasmas. The program was organized into four major sessions sequentially treating: the fundamental science of visible and near-visible radiation in plasmas; the technology of discharge light sources; recent and novel methods for the generation of plasmas; and an update on advances in laser-based diagnostics. Each major session culmi nated in a panel discussion comprised of the Lecturers for that session.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 604 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -Suppose an accountant discovers evidence of shady practices while ex amining the books of a client. What should he or she do Accountants have a professional obligation to respect the confidentiality of their cli ents' accounts. But, as an ordinary citizen, our accountant may feel that the authorities ought to be informed. Suppose a physician discov ers that a patient, a bus driver, has a weak heart. If the patient contin ues bus driving even after being informed of the heart condition, should the physician inform the driver's company Respect for patient confidentiality would say, no. But what if the driver should suffer a heart attack while on duty, causing an accident in which people are killed or seriously injured Would the doctor bear some responsibility for these consequences Special obligations, such as those of confidentiality, apply to any one in business or the professions. These obligations articulate, at least in part, what it is for someone to be, say, an accountant or a physician. Since these obligations are special, they raise a real possibility of con flict with the moral principles we usually accept outside of these spe cial relationships in business and the professions. These conflicts may become more accentuated for a professional who is also a corporate employee-a corporate attorney, an engineer working for a construction company, a nurse working as an employee of a hospital.Springer-Verlag GmbH, Tiergartenstr. 17, 69121 Heidelberg 348 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -There are many kinds of books on formal logic. Some have philosophers as their intended audience, some mathematicians, some computer scien tists. Although there is a common core to all such books, they will be very different in emphasis, methods, and even appearance. This book is intended for computer scientists. But even this is not precise. Within computer science formal logic turns up in a number of areas, from pro gram verification to logic programming to artificial intelligence. This book is intended for computer scientists interested in automated theo rem proving in classical logic. To be more precise yet, it is essentially a theoretical treatment, not a how-to book, although how-to issues are not neglected. This does not mean, of course, that the book will be of no interest to philosophers or mathematicians. It does contain a thorough presentation of formal logic and many proof techniques, and as such it contains all the material one would expect to find in a course in formal logic covering completeness but, not incompleteness issues. The first item to be addressed is, What are we talking about and why are we interested in it We are primarily talking about truth as used in mathematical discourse, and our interest in it is, or should be, self evident. Truth is a semantic concept, so we begin with models and their properties. These are used to define our subject. 348 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The subject of the book is a biography of the theoretical physicist Arnold Sommerfeld (1868-1951). Although Sommerfeld is famous as a quantum theorist for the elaboration of the semi-classical atomic theory (Bohr-Sommerfeld model, Sommerfeld's fine-structure constant), his role in the history of modern physics is not confined to atoms and quanta. Sommerfeld left his mark in the history of mathematics, fluid mechanics, a number of physical subdisciplines and, in particular, as founder of a most productive 'school' (Peter Debye, Wolfgang Pauli, Werner Heisenberg, Linus Pauling and Hans Bethe were his pupils, to name only the Nobel laureates among them). This biography is to a large extent based on primary source material (correspondence, diaries, unpublished manuscripts). It should be of particular interest to students who are keen to know more about the historical roots of modern science. Sommerfeld lived through turbulent times of German history (Wilhelmian Empire, Weimar Republic, Nazi period). His life, therefore, illustrates how science and scientists perform in changing social environments. From this perspective, the biography should also attract readers with a general interest in the history of science and technology. 488 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Rcpp is the glue that binds the power and versatility of R with the speed and efficiency of C++. With Rcpp, the transfer of data between R and C++ is nearly seamless, and high-performance statistical computing is finally accessible to most R users. Rcpp should be part of every statistician's toolbox. -- Michael Braun, MIT Sloan School of Management 'Seamless R and C++ integration with Rcpp' is simply a wonderful book. For anyone who uses C/C++ and R, it is an indispensable resource. The writing is outstanding. A huge bonus is the section on applications. This section covers the matrix packages Armadillo and Eigen and the GNU Scientific Library as well as RInside which enables you to use R inside C++. These applications are what most of us need to know to really do scientific programming with R and C++. I love this book. -- Robert McCulloch, University of Chicago Booth School of Business Rcpp is now considered an essential package for anybody doing serious computational research using R. Dirk's book is an excellent companion and takes the reader from a gentle introduction to more advanced applications via numerous examples and efficiency enhancing gems. The book is packed with all you might have ever wanted to know about Rcpp, its cousins (RcppArmadillo, RcppEigen .etc.), modules, package development and sugar. Overall, this book is a must-have on your shelf. -- Sanjog Misra, UCLA Anderson School of ManagementThe Rcpp package represents a major leap forward for scientific computations with R. With very few lines of C++ code, one has R's data structures readily at hand for further computations in C++. Hence, high-level numerical programming can be made in C++ almost as easily as in R, but often with a substantial speed gain. Dirk is a crucial person in these developments, and his book takes the reader from the first fragile steps on to using the full Rcpp machinery. A very recommended book! --Søren Højsgaard, Department of Mathematical Sciences, Aalborg University, Denmark 'Seamless R and C ++ Integration with Rcpp' provides the first comprehensive introduction to Rcpp. Rcpp has become the most widely-used language extension for R, and is deployed by over one-hundred different CRAN and BioConductor packages. Rcpp permits users to pass scalars, vectors, matrices, list or entire R objects back and forth between R and C++ with ease. This brings the depth of the R analysis framework together with the power, speed, and efficiency of C++.Dirk Eddelbuettel has been a contributor to CRAN for over a decade and maintains around twenty packages. He is the Debian/Ubuntu maintainer for R and other quantitative software, edits the CRAN Task Views for Finance and High-Performance Computing, is a co-founder of the annual R/Finance conference, and an editor of the Journal of Statistical Software. He holds a Ph.D. in Mathematical Economics from EHESS (Paris), and works in Chicago as a Senior Quantitative Analyst. 248 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is an articulate, concise, contemporary introduction to the study of important variables underlying cardiovascular reactivity. Its strength is in the combination of a scholarly but nonpedantic approach to cardiovascular psychophysiology and a solid understanding of be havioral medicine approaches to the study of hypertension. The topics covered are central to the study of relationships between behavior and cardiovascular reactivity; the list of suggested readings at the end of each chapter provides excellent guidance for more detailed study of specific issues. It has now been more than a dozen years since Plenum Press published Paul Obrist's seminal monograph Cardiovascular Psycho physiology. The volume had a major impact in relating cardiovascular regulation to behaving individuals and in developing thoughtful hy potheses concerning such factors as they might pertain to hypertension. The impact of that work extended across scientific disciplines as well as aross continents. At the time the Obrist book was published, a young psychologist, J. Rick Turner, was completing his Ph. D. thesis in psychol ogy at the University of Birmingham, England, on heart rate reactions to psychological challenge. After continued collaboration for the next several years with his former Ph. D. mentor, Douglas Carroll, Turner joined the Obrist laboratory at the University of North Carolina. Al though Obrist unfortunately died during Turner's tenure in the labora tory, collaboration continued with Kathleen Light and Andrew Sher wood. The enlightened legacy of the North Carolina laboratory can clearly be seen in this text. 260 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nanobiotechnology holds the promise of providing revolutionary insight into aspects biology ranging from fundamental questions such as elucidating molecular mechanisms of brain disorders to extraordinary applications such as the detection of a single cancer cell in a population of a million cells. The second edition of Nanobiotechnology Protocols expands upon the previous editions with current, detailed protocols for nanobiotechnology; imaging and detection. With new chapters that explore nano-bio constructs and toxicology of nanomaterials. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Nanobiotechnology Protocol, Second Edition highlights important current areas of development and directions of the field for the future. 208 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Urological Emergencies: A Practical Approach, Second Edition provides a concise, evidence based review of common urgent and emergent urological conditions in children and adults. Descriptions of the appropriate diagnostic and therapeutic considerations on topics of traumatic, infectious, obstructive, hemorrhagic, iatrogenic, vascular and congenital urological emergencies in adults and children are provided. The text is organized by pathophysiology rather than organ system, allowing the reader to develop approaches to the care of patients with acute urological conditions based on mechanism of disease. Relevant pathophysiological background and epidemiology are reviewed, necessary diagnostic testing recommended, and detailed medical, surgical and endourological management approaches have been provided. All chapters incorporate published guidelines and best practice recommendations from appropriate organizations including the American Urological Association, the Centers for Disease Control and Prevention, and various International Consultations on Urological Diseases. New or significantly revised chapters in each of the subsections address innovations in trauma care and prevention, new strategies in management of kidney stones, and special care needs of children with acute urological problems.Urological Emergencies: A Practical Approach, Second Edition is of great value to practicing urologists, urology residents, emergency medicine trainees and practitioners, and primary care providers including MD's, PA's, and NP's without immediate access to urological consultation. 356 pp. Englisch.

Buch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Embryonic stem cells and adult stem cells are the two major types of stem cells that have been used for experimental and clinical studies. Embryonic stem cells are totipotent cells that have the capability to differentiate into any type of cell in the body. In Cellular Cardiomyoplasty: Methods and Protocols, expert researchers in the field detail many of the methods which are now commonly used to study cellular cardiomyoplasty. Methods and techniques described in this volume use only adult stem cells or adult progenitor cells.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and Practical, Cellular Cardiomyoplasty: Methods and Protocols will benefit the cardiologist, cardiothoracic surgeons, biologist (cell, molecular, or structural), biochemist, and physiologist who are interested in understanding and treating damaged myocardium and failing heart. 228 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Experienced cancer researchers from pharmaceutical companies, government laboratories, and academia comprehensively review and describe the arduous process of cancer drug discovery and approval. They focus on using preclinical in vivo and in vitro methods to identify molecules of interest, detailing the targets and criteria for success in each type of testing and defining the value of the information obtained from the various tests. They also define each stage of clinical testing, explain the criteria for success, and outline the requirements for FDA approval. A companion volume by the same editor (Cancer Therapeutics: Experimental and Clinical Agents) reviews existing anticancer drugs and potential anticancer therapies. These two volumes in the Cancer Drug Discovery and Development series reveal how and why molecules become anticancer drugs and thus offer a blueprint for the present and the future of the field. 328 pp. Englisch.