Humana aug 2016 (Más de 1600 resultados)

Taschenbuch. Condición: Neu. Neuware -This text introduces upper division undergraduate/beginning graduate students in mathematics, finance, or economics, to the core topics of a beginning course in finance/financial engineering. Particular emphasis is placed on exploiting the power of the Monte Carlo method to illustrate and explore financial principles. Monte Carlo is the uniquely appropriate tool for modeling the random factors that drive financial markets and simulating their implications.The Monte Carlo method is introduced early and it is used in conjunction with the geometric Brownian motion model (GBM) to illustrate and analyze the topics covered in the remainder of the text. Placing focus on Monte Carlo methods allows for students to travel a short road from theory to practical applications. Coverage includes investment science, mean-variance portfolio theory, option pricing principles, exotic options, option trading strategies, jump diffusion and exponential Lévy alternative models, and the Kelly criterion for maximizing investment growth.Novel features:inclusion of both portfolio theory and contingent claim analysis in a single textpricing methodology for exotic optionsexpectation analysis of option trading strategiespricing models that transcend the Black-Scholes frameworkoptimizing investment allocationsconcepts thoroughly explored through numerous simulation exercisesnumerous worked examples and illustrationsThe mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. The mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. Also by the author: (with F. Mendivil) Explorations in Monte Carlo, (c)2009, ISBN: 978-0-387-87836-2; (with J. Herod) Mathematical Biology: An Introduction with Maple and Matlab, Second edition, (c)2009, ISBN: 978-0-387-70983-3.…

Taschenbuch. Condición: Neu. Neuware -Pattern recognition has its origins in engineering, whereas machine learning grew out of computer science. However, these activities can be viewed as two facets of the same field, and together they have undergone substantial development over the past ten years. In particular, Bayesian methods have grown from a specialist niche to become mainstream, while graphical models have emerged as a general framework for describing and applying probabilistic models. Also, the practical applicability of Bayesian methods has been greatly enhanced through the development of a range of approximate inference algorithms such as variational Bayes and expectation pro- gation. Similarly, new models based on kernels have had significant impact on both algorithms and applications. This new textbook reacts these recent developments while providing a comprehensive introduction to the fields of pattern recognition and machine learning. It is aimed at advanced undergraduates or first year PhD students, as wellas researchers and practitioners, and assumes no previous knowledge of pattern recognition or - chine learning concepts. Knowledge of multivariate calculus and basic linear algebra is required, and some familiarity with probabilities would be helpful though not essential as the book includes a self-contained introduction to basic probability theory. 760 pp. Englisch. …

Taschenbuch. Condición: Neu. Neuware - This text introduces upper division undergraduate/beginning graduate students in mathematics, finance, or economics, to the core topics of a beginning course in finance/financial engineering. Particular emphasis is placed on exploiting the power of the Monte Carlo method to illustrate and explore financial principles. Monte Carlo is the uniquely appropriate tool for modeling the random factors that drive financial markets and simulating their implications.The Monte Carlo method is introduced early and it is used in conjunction with the geometric Brownian motion model (GBM) to illustrate and analyze the topics covered in the remainder of the text. Placing focus on Monte Carlo methods allows for students to travel a short road from theory to practical applications. Coverage includes investment science, mean-variance portfolio theory, option pricing principles, exotic options, option trading strategies, jump diffusion and exponential Lévy alternative models, and the Kelly criterion for maximizing investment growth.Novel features:inclusion of both portfolio theory and contingent claim analysis in a single textpricing methodology for exotic optionsexpectation analysis of option trading strategiespricing models that transcend the Black-Scholes frameworkoptimizing investment allocationsconcepts thoroughly explored through numerous simulation exercisesnumerous worked examples and illustrationsThe mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. The mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. Also by the author: (with F. Mendivil) Explorations in Monte Carlo, 2009, ISBN: 978-0-387-87836-2; (with J. Herod) Mathematical Biology: An Introduction with Maple and Matlab, Second edition, 2009, ISBN: 978-0-387-70983-3.…

Taschenbuch. Condición: Neu. Neuware -Providing experimental methods and protocols for performing pheromone research in a variety of organisms ranging from invertebrates to vertebrates, Pheromone Signaling: Methods and Protocols covers a wide spectrum of experimental approaches necessary for handling pheromone molecules, measuring receptor response and neural activation, and analyzing behavioral output. A great deal of progress has been made in understanding the molecular mechanisms underlying pheromone action, largely due to the discovery of receptor genes, the advancement of imaging techniques, and key multi-disciplinary approaches including aspects of organic chemistry, biochemistry, molecular biology, electrophysiology, and behavioral science. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and practical, Pheromone Signaling: Methods and Protocols details the key methodologies utilized in laboratories all over the world, making them accessible to those who want to begin investigation in the area of pheromone research. 416 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - Through its scope and depth of coverage, this book addresses the needs of the vibrant and rapidly growing engineering fields, bioengineering and biomedical engineering, while implementing software that engineers are familiar with.The author integrates introductory statistics for engineers and introductory biostatistics as a single textbook heavily oriented to computation and hands on approaches. For example, topics ranging from the aspects of disease and device testing, Sensitivity, Specificity and ROC curves, Epidemiological Risk Theory, Survival Analysis, or Logistic and Poisson Regressions are covered.In addition to the synergy of engineering and biostatistical approaches, the novelty of this book is in the substantial coverage of Bayesian approaches to statistical inference. Many examples in this text are solved using both the traditional and Bayesian methods, and the results are compared and commented.…

Taschenbuch. Condición: Neu. Neuware -The discovery of DNA as the genetic material brought great hope to scientists all over the world. It was believed that many of the lingering questions in genetics and the mechanisms of heredity would fnally be answered. However, as often is the case in science, more qu- tions arose out of this discovery. What defnes a gene What are the mechanisms of gene regulation Further discovery and technological innovations brought about sequencing techniques that allowed the study of complete genomes from many organisms, including Arabidopsis and humans. Despite all the excitement surrounding these technologies, many features of the genome remained unclear. Peculiar characteristics in genome composition such as signifcant redundancy consisting of many repetitive elements and noncoding sequences, active transcriptional units with no protein product, and unusual sequences in promoter regions added to the mysteries of genetic make-up and gene regulation. Indeed, the more we discovered about the genome, the more diffcult it became to understand the complexity of cellular function and regulation. Out of the study of the intricacies of the genome and gene regulation, arose a new science that was independent of actual DNA changes, but critical in maintaining gene regulation and genetic stability. Epigenetics, literally translated as ¿above genetics,¿ is the science that describes the mechanisms of heritable changes in gene regulation that does not involve modifcations of DNA sequence. These changes may last through somatic cell division and, in some cases, throughout multiple generations. …

Taschenbuch. Condición: Neu. Neuware -Due to the complexity of the mitochondrial system and the myriad genes involved in their function, the clinical manifestations of mitochondrial diseases are remarkably variable and heterogeneous. The laboratory and clinical methodologies used to evaluate dysfunction may vary widely, and thusly a systematic presentation of the numerous protocols that are applied to the assessment of these clinically and genetically heterogeneous disorders has proven to be essential. Mitochondrial Disorders: Biochemical and Molecular Analysis strives to fill this need with a collection of key protocols provided by leading experts in the field. Beginning with overviews of complexity of mitochondrial and nuclear genome disorders, the book continues with a section devoted to current biochemical protocols and a part focused on the DNA-based approaches used to identify molecular defects. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters contain introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Detailed and authoritative, Mitochondrial Disorders: Biochemical and Molecular Analysis serves as a vital guide to researchers seeking to understand this incredibly complicated type of breakdown in cellular biology. 364 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware -This text introduces upper division undergraduate/beginning graduate students in mathematics, finance, or economics, to the core topics of a beginning course in finance/financial engineering. Particular emphasis is placed on exploiting the power of the Monte Carlo method to illustrate and explore financial principles. Monte Carlo is the uniquely appropriate tool for modeling the random factors that drive financial markets and simulating their implications.The Monte Carlo method is introduced early and it is used in conjunction with the geometric Brownian motion model (GBM) to illustrate and analyze the topics covered in the remainder of the text. Placing focus on Monte Carlo methods allows for students to travel a short road from theory to practical applications. Coverage includes investment science, mean-variance portfolio theory, option pricing principles, exotic options, option trading strategies, jump diffusion and exponential Lévy alternative models, and the Kelly criterion for maximizing investment growth.Novel features:inclusion of both portfolio theory and contingent claim analysis in a single textpricing methodology for exotic optionsexpectation analysis of option trading strategiespricing models that transcend the Black-Scholes frameworkoptimizing investment allocationsconcepts thoroughly explored through numerous simulation exercisesnumerous worked examples and illustrationsThe mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. The mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. Also by the author: (with F. Mendivil) Explorations in Monte Carlo, (c)2009, ISBN: 978-0-387-87836-2; (with J. Herod) Mathematical Biology: An Introduction with Maple and Matlab, Second edition, (c)2009, ISBN: 978-0-387-70983-3. 272 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - The discovery of DNA as the genetic material brought great hope to scientists all over the world. It was believed that many of the lingering questions in genetics and the mechanisms of heredity would fnally be answered. However, as often is the case in science, more qu- tions arose out of this discovery. What defnes a gene What are the mechanisms of gene regulation Further discovery and technological innovations brought about sequencing techniques that allowed the study of complete genomes from many organisms, including Arabidopsis and humans. Despite all the excitement surrounding these technologies, many features of the genome remained unclear. Peculiar characteristics in genome composition such as signifcant redundancy consisting of many repetitive elements and noncoding sequences, active transcriptional units with no protein product, and unusual sequences in promoter regions added to the mysteries of genetic make-up and gene regulation. Indeed, the more we discovered about the genome, the more diffcult it became to understand the complexity of cellular function and regulation. Out of the study of the intricacies of the genome and gene regulation, arose a new science that was independent of actual DNA changes, but critical in maintaining gene regulation and genetic stability. Epigenetics, literally translated as 'above genetics,' is the science that describes the mechanisms of heritable changes in gene regulation that does not involve modifcations of DNA sequence. These changes may last through somatic cell division and, in some cases, throughout multiple generations. …

Taschenbuch. Condición: Neu. Neuware -The average physician and even cancer care-givers are not knowledgeable about the effects of cancer treatment on sex and reproductive life. They are even less aware of the options available for treatment of such patients. Cancer and Sexual Health fills a great need for a reference work devoted to the link between cancer and human sexuality. The volume is designed to give a comprehensive and state-of-the-art review of the sexual and reproductive consequences of cancer diagnosis and treatment. It will prove an invaluable resource for those clinicians caring for cancer patients as well as acting as a reference text for the sexual medicine clinician who may not see a large number of cancer patients.…

Taschenbuch. Condición: Neu. Neuware -The discovery of DNA as the genetic material brought great hope to scientists all over the world. It was believed that many of the lingering questions in genetics and the mechanisms of heredity would fnally be answered. However, as often is the case in science, more qu- tions arose out of this discovery. What defnes a gene What are the mechanisms of gene regulation Further discovery and technological innovations brought about sequencing techniques that allowed the study of complete genomes from many organisms, including Arabidopsis and humans. Despite all the excitement surrounding these technologies, many features of the genome remained unclear. Peculiar characteristics in genome composition such as signifcant redundancy consisting of many repetitive elements and noncoding sequences, active transcriptional units with no protein product, and unusual sequences in promoter regions added to the mysteries of genetic make-up and gene regulation. Indeed, the more we discovered about the genome, the more diffcult it became to understand the complexity of cellular function and regulation. Out of the study of the intricacies of the genome and gene regulation, arose a new science that was independent of actual DNA changes, but critical in maintaining gene regulation and genetic stability. Epigenetics, literally translated as 'above genetics,' is the science that describes the mechanisms of heritable changes in gene regulation that does not involve modifcations of DNA sequence. These changes may last through somatic cell division and, in some cases, throughout multiple generations. 284 pp. Englisch. …

Taschenbuch. Condición: Neu. Neuware - The average physician and even cancer care-givers are not knowledgeable about the effects of cancer treatment on sex and reproductive life. They are even less aware of the options available for treatment of such patients. Cancer and Sexual Health fills a great need for a reference work devoted to the link between cancer and human sexuality. The volume is designed to give a comprehensive and state-of-the-art review of the sexual and reproductive consequences of cancer diagnosis and treatment. It will prove an invaluable resource for those clinicians caring for cancer patients as well as acting as a reference text for the sexual medicine clinician who may not see a large number of cancer patients.…

Taschenbuch. Condición: Neu. Neuware -The average physician and even cancer care-givers are not knowledgeable about the effects of cancer treatment on sex and reproductive life. They are even less aware of the options available for treatment of such patients. Cancer and Sexual Health fills a great need for a reference work devoted to the link between cancer and human sexuality. The volume is designed to give a comprehensive and state-of-the-art review of the sexual and reproductive consequences of cancer diagnosis and treatment. It will prove an invaluable resource for those clinicians caring for cancer patients as well as acting as a reference text for the sexual medicine clinician who may not see a large number of cancer patients. 804 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware -The International Handbook of Research on Teachers and Teaching provides a fresh look at the ever changing nature of the teaching profession throughout the world. This collection of over 70 original articles addresses a wide range of issues that are relevant for understanding the present educational climate in which the accountability of teachers and the standardized testing of students have become dominant.The international collection of authors brings to the handbook a breadth of knowledge and experience about the teaching profession and a wealth of material across a number of comparative dimensions, such as between developed and developing countries and between Eastern and Western cultures. In addition, many articles address the emerging challenges to education and to the lives of teachers which are brought about by the globalization trends of the 21st Century. 1248 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - The International Handbook of Research on Teachers and Teaching provides a fresh look at the ever changing nature of the teaching profession throughout the world. This collection of over 70 original articles addresses a wide range of issues that are relevant for understanding the present educational climate in which the accountability of teachers and the standardized testing of students have become dominant.The international collection of authors brings to the handbook a breadth of knowledge and experience about the teaching profession and a wealth of material across a number of comparative dimensions, such as between developed and developing countries and between Eastern and Western cultures. In addition, many articles address the emerging challenges to education and to the lives of teachers which are brought about by the globalization trends of the 21st Century.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This textbook is distinguished from other texts on the subject by the depth of the presentation and the discussion of the calculus of moving surfaces, which is an extension of tensor calculus to deforming manifolds. Designed for advanced undergraduate and graduate students, this text invites its audience to take a fresh look at previously learned material through the prism of tensor calculus. Once the framework is mastered, the student is introduced to new material which includes differential geometry on manifolds, shape optimization, boundary perturbation and dynamic fluid film equations. The language of tensors, originally championed by Einstein, is as fundamental as the languages of calculus and linear algebra and is one that every technical scientist ought to speak. The tensor technique, invented at the turn of the 20th century, is now considered classical. Yet, as the author shows, it remains remarkably vital and relevant. The author's skilled lecturing capabilities are evident by the inclusion of insightful examples and a plethora of exercises. A great deal of material is devoted to the geometric fundamentals, the mechanics of change of variables, the proper use of the tensor notation and the discussion of the interplay between algebra and geometry. The early chapters have many words and few equations. The definition of a tensor comes only in Chapter 6 - when the reader is ready for it. While this text maintains a consistent level of rigor, it takes great care to avoid formalizing the subject. The last part of the textbook is devoted to the Calculus of Moving Surfaces. It is the first textbook exposition of this important technique and is one of the gems of this text. A number of exciting applications of the calculus are presented including shape optimization, boundary perturbation of boundary value problemsand dynamic fluid film equations developed by the author in recent years. Furthermore, the moving surfaces framework is used to offer new derivations of classical results such as the geodesic equation and the celebrated Gauss-Bonnet theorem. 316 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This undergraduate textbook introduces students to the basics of real analysis, provides an introduction to more advanced topics including measure theory and Lebesgue integration, and offers an invitation to functional analysis. While these advanced topics are not typically encountered until graduate study, the text is designed for the beginner. The author's engaging style makes advanced topics approachable without sacrificing rigor. The text also consistently encourages the reader to pick up a pencil and take an active part in the learning process. Key features include: - examples to reinforce theory; - thorough explanations preceding definitions, theorems and formal proofs; - illustrations to support intuition; - over 450 exercises designed to develop connections between the concrete and abstract. This text takes students on a journey through the basics of real analysis and provides those who wish to delve deeper the opportunity to experience mathematical ideas that are beyond the standard undergraduate curriculum. 428 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This text introduces upper division undergraduate/beginning graduate students in mathematics, finance, or economics, to the core topics of a beginning course in finance/financial engineering. Particular emphasis is placed on exploiting the power of the Monte Carlo method to illustrate and explore financial principles. Monte Carlo is the uniquely appropriate tool for modeling the random factors that drive financial markets and simulating their implications.The Monte Carlo method is introduced early and it is used in conjunction with the geometric Brownian motion model (GBM) to illustrate and analyze the topics covered in the remainder of the text. Placing focus on Monte Carlo methods allows for students to travel a short road from theory to practical applications. Coverage includes investment science, mean-variance portfolio theory, option pricing principles, exotic options, option trading strategies, jump diffusion and exponential Lévy alternative models, and the Kelly criterion for maximizing investment growth.Novel features:inclusion of both portfolio theory and contingent claim analysis in a single textpricing methodology for exotic optionsexpectation analysis of option trading strategiespricing models that transcend the Black-Scholes frameworkoptimizing investment allocationsconcepts thoroughly explored through numerous simulation exercisesnumerous worked examples and illustrationsThe mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. The mathematical background required is a year and one-half course in calculus, matrix algebra covering solutions of linear systems, and a knowledge of probability including expectation, densities and the normal distribution. A refresher for these topics is presented in the Appendices. The programming background needed is how to code branching, loops and subroutines in some mathematical or general purpose language. Also by the author: (with F. Mendivil) Explorations in Monte Carlo, 2009, ISBN: 978-0-387-87836-2; (with J. Herod) Mathematical Biology: An Introduction with Maple and Matlab, Second edition, 2009, ISBN: 978-0-387-70983-3. 272 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents various results and techniques from the theory of stochastic processes that are useful in the study of stochastic problems in the natural sciences. The main focus is analytical methods, although numerical methods and statistical inference methodologies for studying diffusion processes are also presented. The goal is the development of techniques that are applicable to a wide variety of stochastic models that appear in physics, chemistry and other natural sciences. Applications such as stochastic resonance, Brownian motion in periodic potentials and Brownian motors are studied and the connection between diffusion processes and time-dependent statistical mechanics is elucidated.The book contains a large number of illustrations, examples, and exercises. It will be useful for graduate-level courses on stochastic processes for students in applied mathematics, physics and engineering. Many of the topics covered in this book (reversible diffusions, convergence toequilibrium for diffusion processes, inference methods for stochastic differential equations, derivation of the generalized Langevin equation, exit time problems) cannot be easily found in textbook form and will be useful to both researchers and students interested in the applications of stochastic processes. 356 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This richly illustrated textbook explores the amazing interaction between combinatorics, geometry, number theory, and analysis which arises in the interplay between polyhedra and lattices. Highly accessible to advanced undergraduates, as well as beginning graduate students, this second edition is perfect for a capstone course, and adds two new chapters, many new exercises, and updated open problems. For scientists, this text can be utilized as a self-contained tooling device.The topics include a friendly invitation to Ehrhart's theory of counting lattice points in polytopes, finite Fourier analysis, the Frobenius coin-exchange problem, Dedekind sums, solid angles, Euler-Maclaurin summation for polytopes, computational geometry, magic squares, zonotopes, and more.With more than 300 exercises and open research problems, the reader is an active participant, carried through diverse but tightly woven mathematical fields that are inspired by an innocently elementary question: What are the relationships between the continuous volume of a polytope and its discrete volume Reviews of the first edition:'You owe it to yourself to pick up a copy of Computing the Continuous Discretely to read about a number of interesting problems in geometry, number theory, and combinatorics.'- MAA Reviews'The book is written as an accessible and engaging textbook, with many examples, historical notes, pithy quotes, commentary integrating the material, exercises, open problems and an extensive bibliography.'- Zentralblatt MATH'This beautiful book presents, at a level suitable for advanced undergraduates, a fairly complete introduction to the problem of counting lattice points inside a convex polyhedron.'- Mathematical Reviews'Many departments recognize the need for capstone courses in which graduating students can see the tools they have acquired come together in some satisfying way. Beck and Robinshave written the perfect text for such a course.'- CHOICE 308 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Considerable advances have taken place since the initial isolation and characterization of human embryonic stem (HES) cells; however, significant challenges remain before their potential for restoration and regeneration processes in patients can be realized. Understanding the diversity amongst HES cell lines and realizing the ability to isolate lines with robust differentiation potential remain difficult. In the Human Embryonic Stem Cells Handbook, experts in the field provide an assortment of protocols that have been used by various laboratories around the world so as to allow both novices and experienced investigators to compare and contrast different approaches to HES cell isolation and characterization with the hope that, from these protocols, researchers might standardize approaches for HES cell biology. Written in the Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips for troubleshooting and avoiding known pitfalls. Authoritative and accessible, Human Embryonic Stem Cells Handbook serves as a valuable reference for scientists pursuing this vital field and its enormous potential. 328 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As scientist begin to understand the complexity of lipid signaling and its roles in plant biology, there is an increasing interest in their analysis. Due to the low abundancy and transient nature of some of these hydrophobic compounds, this is not always easy. In Plant Lipid Signaling Protocols, expert researchers in the field detail experimental approaches by which plant signaling lipids can be studied. These methods and techniques include analysis of plant signaling lipids, including detailed protocols to detect various relevant compounds by targeted or non-targeted approaches; to assay relevant enzyme activities in biological material or using recombinant enzymes; to test for specific binding of signaling lipids to protein partners; or to visualize signaling lipids or lipid-derived signals in living plant cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Plant Lipid Signaling Protocols aids plant researchers in the continuing to study the roles of lipid signals. 320 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Understanding gene expression and how it changes under normal and pathological conditions is essential to our understanding of the fundamentals of cell biology through to the targeted treatment of disease. In Gene Expression Profiling: Methods and Protocols, Second Edition, experts in their particular fields compile detailed protocols for a broad range of techniques, currently available and being further developed, for the analysis of gene expression at the DNA, RNA, and protein levels. Written in the highly successful Methods in Molecular Biology(TM) series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Practical and easy-to-use, Gene Expression Profiling: Methods and Protocols, Second Edition presents a collection of clearly described and illustrated chapters, certain to be helpful to researchers in academia, in hospitals, and in industry who are interested in applying techniques, whether basic or advanced, for the analysis of gene expression. 224 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -The Art of Proof is designed for a one-semester or two-quarter course. A typical student will have studied calculus (perhaps also linear algebra) with reasonable success. With an artful mixture of chatty style and interesting examples, the student's previous intuitive knowledge is placed on solid intellectual ground. The topics covered include: integers, induction, algorithms, real numbers, rational numbers, modular arithmetic, limits, and uncountable sets. Methods, such as axiom, theorem and proof, are taught while discussing the mathematics rather than in abstract isolation. Some of the proofs are presented in detail, while others (some with hints) may be assigned to the student or presented by the instructor. The authors recommend that the two parts of the book -- Discrete and Continuous -- be given equal attention. The book ends with short essays on further topics suitable for seminar-style presentation by small teams of students, either in class or in a mathematics club setting. These include: continuity, cryptography, groups, complex numbers, ordinal number, and generating functions.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 204 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Pattern recognition has its origins in engineering, whereas machine learning grew out of computer science. However, these activities can be viewed as two facets of the same field, and together they have undergone substantial development over the past ten years. In particular, Bayesian methods have grown from a specialist niche to become mainstream, while graphical models have emerged as a general framework for describing and applying probabilistic models. Also, the practical applicability of Bayesian methods has been greatly enhanced through the development of a range of approximate inference algorithms such as variational Bayes and expectation pro- gation. Similarly, new models based on kernels have had significant impact on both algorithms and applications. This new textbook reacts these recent developments while providing a comprehensive introduction to the fields of pattern recognition and machine learning. It is aimed at advanced undergraduates or first year PhD students, as wellas researchers and practitioners, and assumes no previous knowledge of pattern recognition or - chine learning concepts. Knowledge of multivariate calculus and basic linear algebra is required, and some familiarity with probabilities would be helpful though not essential as the book includes a self-contained introduction to basic probability theory. 760 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This engineering dynamics textbook is aimed at beginning graduate students in mechanical engineering and other related engineering disciplines who need training in dynamics as applied to engineering mechanisms. It introduces the formal mathematical development of Lagrangian mechanics (and its corollaries), while solving numerous engineering applications.The author¿s goal is to instill an understanding of the basic physics required for engineering dynamics, while providing a recipe (algorithm) for the simulation of engineering mechanisms such as robots.The book will be reasonably self-contained so that the practicing engineer interested in this area can also make use of it.This book is made accessible to the widest possible audience by numerous, solved examples and diagrams that apply the principles to real engineering applications.¿Provides an applied textbook for intermediate/advanced engineering dynamics courses;¿Discusses Lagrangian mechanics in the context of numerous engineering applications;¿Includes numerous, solved examples, illustrative diagrams and applied exercises in every chapterSpringer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 284 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume is meant to provide the practitioner with information on the natural mixing processes occurring in aquifers as well as to describe basic strategies that can be implemented to enhance mixing in particular cases. For example, when it comes to mixing miscible liquids, one can speed up mixing in the formation by manipulating the flow such as through the use of recirculation wells. Furthermore, much of the mixing can be achieved partially within recirculation wells themselves, where contaminated water is admixed with additives, volatile products may be removed through a vapor mass exchanger, etc. Thus, adding mixing wells can significantly increase the performance of the delivery and mixing system and speed up the process of remediation.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 356 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This undergraduate textbook introduces students to the basics of real analysis, provides an introduction to more advanced topics including measure theory and Lebesgue integration, and offers an invitation to functional analysis. While these advanced topics are not typically encountered until graduate study, the text is designed for the beginner. The author¿s engaging style makes advanced topics approachable without sacrificing rigor. The text also consistently encourages the reader to pick up a pencil and take an active part in the learning process. Key features include: - examples to reinforce theory; - thorough explanations preceding definitions, theorems and formal proofs; - illustrations to support intuition; - over 450 exercises designed to develop connections between the concrete and abstract. This text takes students on a journey through the basics of real analysis and provides those who wish to delve deeper the opportunity to experience mathematical ideas that are beyond the standard undergraduate curriculum.Springer-Verlag KG, Sachsenplatz 4-6, 1201 Wien 428 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -This volume presents detailed, recently-developed protocols ranging from isolation of nuclei to purification of chromatin regions containing single genes, with a particular focus on some less well-explored aspects of the nucleus. The methods described include new strategies for isolation of nuclei, for purification of cell type-specific nuclei from a mixture, and for rapid isolation and fractionation of nucleoli. For gene delivery into and expression in nuclei, a novel gentle approach using gold nanowires is presented. As the concentration and localization of water and ions are crucial for macromolecular interactions in the nucleus, a new approach to measure these parameters by correlative optical and cryo-electron microscopy is described. The Nucleus, Second Edition presents methods and software for high-throughput quantitative analysis of 3D fluorescence microscopy images, for quantification of the formation of amyloid fibrils in the nucleus, and for quantitative analysis of chromosome territory localization. Written in the successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.Authoritative and easily accessible, The Nucleus, Second Edition seeks to serve both professionals and novices with its well-honed methods for the study of the nucleus.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 252 pp. Englisch.…

Taschenbuch. Condición: Neu. This item is printed on demand - Print on Demand Titel. Neuware -In Apoptosis and Cancer: Methods and Protocols, Second Edition, expert researches in the field detail the performance of molecular and cellular biology techniques for studying and detecting the activation of the apoptotic pathway. Chapters focus on assays developed to detect its activation not only in vitro but also in vivo, optimized multiplex analysis, medium- to high-throughput screens, and the cellular process. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.Authoritative and practical, Apoptosis and Cancer: Methods and Protocols, Second Edition aids scientists as a stand-alone resource for the execution and analysis of the described protocols and as a reference for the study and detection of apoptosis within and outside the area of cancer research.Libri GmbH, Europaallee 1, 36244 Bad Hersfeld 220 pp. Englisch.…