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  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032931248 / 9781032931241

    Serie: Libro 3 de 8 - Routledge International Real Estate Markets

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    Taschenbuch. Condición: Neu. Neuware - This in-depth case study evaluates the recent evolution of the Italian real estate market, which has lately been subject to two interlocking phenomena: a serious devaluation of physical assets and, at the same time, a deep legislative innovation of the vehicles investing in this asset class.The novelty of the legal framework of some of the Italian real estate investment vehicles and the recent developments in the market make this detailed analysis a fascinating addition to the literature.The book starts with an analysis of the Italian real estate sector, covering the evolution and performance in light of the economic crisis and the most recent legislative innovations. Italian real estate investment vehicles are then compared with a broader European perspective. Each Italian investment vehicle (real estate investment funds, real estate fixed capital investment companies and real estate investment trusts) is then analysed in both legal and financial details, providing insights into management structure, the rights and powers of investors, the typical investment process and the related costs. The different management models are then compared in order to assess their advantages and disadvantages, especially for institutional investors. The performance measurement of Italian closed-end alternative investment funds and the phenomenon of discount to net asset value for listed real estate investment funds are then subject to a theoretical and empirical examination.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032930799 / 9781032930794

    Serie: Libro 5 de 8 - Global Science Education

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    Taschenbuch. Condición: Neu. Neuware - Students often think of science as disconnected pieces of information rather than a narrative that challenges their thinking, requires them to develop evidence-based explanations for the phenomena under investigation, and communicate their ideas in discipline-specific language as to why certain solutions to a problem work. The author provides teachers in primary and junior secondary school with different evidence-based strategies they can use to teach inquiry science in their classrooms. The research and theoretical perspectives that underpin the strategies are discussed as are examples of how different ones areimplemented in science classrooms to affect student engagement and learning. Key Features: - Presents processes involved in teaching inquiry-based science - Discusses importance of multi-modal representations in teaching inquiry based-science - Covers ways to develop scientifically literacy - Uses the Structure of Observed learning Outcomes (SOLO) Taxonomy to assess student reasoning, problem-solving and learning - Presents ways to promote scientific discourse, including teacher-student interactions, student-student interactions, and meta-cognitive thinking.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    0367300478 / 9780367300470

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    EUR 74,72

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    Taschenbuch. Condición: Neu. Neuware - At the core of the rational expectations revolution is the insight that economic policy does not operate independently of economic agents' knowledge of that policy and their expectations of the effects of that policy. This means that there are very complicated feedback relationships existing between policy and the behaviour of economic agents, and these relationships pose very difficult problems in econometrics when one tries to exploit the rational expectations insight in formal economic modelling. This volume consists of work by two rational expectations pioneers dealing with the nuts and bolts problems of modelling the complications introduced by rational expectations. Each paper deals with aspects of the problem of making inferences about parameters of a dynamic economic model on the basis of time series observations. Each exploits restrictions on an econometric model imposed by the hypothesis that agents within the model have rational expectations.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    0367301741 / 9780367301743

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    EUR 74,76

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    Taschenbuch. Condición: Neu. Neuware - This book reports the proceedings of the symposium, Chinese Rural Development: Strategies and Experience, organized by the China Com-mittee of the American Agricultural Economics Association (AAEA) and held in Baton Rouge, Louisiana, on July 30, 1989. The editors would like to thank members of the committee, listed below, for their time and efforts in planning, organizing, and hosting the symposium.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    0367303841 / 9780367303846

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    Taschenbuch. Condición: Neu. Neuware - Originally published in 1989. The author has the sincere hope that the reforms currently being introduced in the USSR will render much of this book obsolete. Yet, even if perestroika brings significant change to the Soviet Union, historians will want a record of what existed before. After four years, it has become apparent that perestroika is a pai.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    0367302780 / 9780367302788

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    EUR 75,08

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    Taschenbuch. Condición: Neu. Neuware - Presents the latest findings on past changes in structure, the factors that lead to structural change, its effect on societal welfare and what will happen to the structure of agriculture in the years ahead. The book provides insights on issues such as the family farm, the industrialization of agriculture and the impact of agricultural technology on the environment.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    0367304570 / 9780367304577

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    EUR 74,83

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    Taschenbuch. Condición: Neu. Neuware - This book is the second in a series on arctic and alpine environments produced by Dr. Michael Vigdorchik at the Institute of Arctic and Alpine Research (INSTAAR), University of Colorado, Boulder. The first carried the title Arctic Pleistocene History and the Development of Submarine Permafrost. The complicated Arctic Basin development during the Pleistocene has been described in that book, including the paleoenvironmental problems posed by the isolation of the Arctic Basin during the Ice Ages. This sequel concerns the identification and estimation of the potential hazards posed by the arctic environment to petroleum exploration and development on the Alaskan continental shelf.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032920394 / 9781032920399

    Serie: Libro 42 de 110 - ISSN

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    EUR 90,34

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    Taschenbuch. Condición: Neu. Neuware - Despite research interest in functional data analysis in the last three decades, few books are available on the subject. Filling this gap, Analysis of Variance for Functional Data presents up-to-date hypothesis testing methods for functional data analysis. The book covers the reconstruction of functional observations, functional ANOVA, functional linear models with functional responses, ill-conditioned functional linear models, diagnostics of functional observations, heteroscedastic ANOVA for functional data, and testing equality of covariance functions. Although the methodologies presented are designed for curve data, they can be extended to surface data.Useful for statistical researchers and practitioners analyzing functional data, this self-contained book gives both a theoretical and applied treatment of functional data analysis supported by easy-to-use MATLAB® code. The author provides a number of simple methods for functional hypothesis testing. He discusses pointwise, L2-norm-based, F-type, and bootstrap tests. Assuming only basic knowledge of statistics, calculus, and matrix algebra, the book explains the key ideas at a relatively low technical level using real data examples. Each chapter also includes bibliographical notes and exercises. Real functional data sets from the text and MATLAB codes for analyzing the data examples are available for download from the author's website.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032919957 / 9781032919959

    Serie: Libro 3 de 8 - Chapman & Hall/CRC Mathematical and Computational Imaging Sciences

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    Taschenbuch. Condición: Neu. Neuware - The massive amount of nonstandard high-dimensional brain imaging data being generated is often difficult to analyze using current techniques. This challenge in brain image analysis requires new computational approaches and solutions. But none of the research papers or books in the field describe the quantitative techniques with detailed illustrations of actual imaging data and computer codes. Using MATLAB® and case study data sets, Statistical and Computational Methods in Brain Image Analysis is the first book to explicitly explain how to perform statistical analysis on brain imaging data. The book focuses on methodological issues in analyzing structural brain imaging modalities such as MRI and DTI. Real imaging applications and examples elucidate the concepts and methods. In addition, most of the brain imaging data sets and MATLAB codes are available on the author's website.By supplying the data and codes, this book enables researchers to start their statistical analyses immediately. Also suitable for graduate students, it provides an understanding of the various statistical and computational methodologies used in the field as well as important and technically challenging topics.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    103243435X / 9781032434353

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    Taschenbuch. Condición: Neu. Neuware - Interdisciplinary Rheumatology: Rheumatology and Gastroenterology is the first complete textbook to examine the myriad complications of rheumatic syndromes in the gastrointestinal tract. Each disease is summarized for a broad medical audience, with focus on the consequences of the disorder throughout the gut. The reader will formulate an understanding of the clinical, pharmacological, and nutritional aspects of the interface of these two specialties with expert contributors from a range of academic centers. Rheumatologists and gastroenterologists will be able to recognize, evaluate, and treat gastrointestinal symptoms of autoimmune diseases and collaborate in improving the experience and outcomes of these complex patients.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032925159 / 9781032925158

    Serie: Libro 37 de 110 - ISSN

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    Taschenbuch. Condición: Neu. Neuware - There is a huge amount of literature on statistical models for the prediction of survival after diagnosis of a wide range of diseases like cancer, cardiovascular disease, and chronic kidney disease. Current practice is to use prediction models based on the Cox proportional hazards model and to present those as static models for remaining lifetime after diagnosis or treatment. In contrast, Dynamic Prediction in Clinical Survival Analysis focuses on dynamic models for the remaining lifetime at later points in time, for instance using landmark models. Designed to be useful to applied statisticians and clinical epidemiologists, each chapter in the book has a practical focus on the issues of working with real life data. Chapters conclude with additional material either on the interpretation of the models, alternative models, or theoretical background. The book consists of four parts: - Part I deals with prognostic models for survival data using (clinical) information available at baseline, based on the Cox model - Part II is about prognostic models for survival data using (clinical) information available at baseline, when the proportional hazards assumption of the Cox model is violated - Part III is dedicated to the use of time-dependent information in dynamic prediction - Part IV explores dynamic prediction models for survival data using genomic data Dynamic Prediction in Clinical Survival Analysis summarizes cutting-edge research on the dynamic use of predictive models with traditional and new approaches. Aimed at applied statisticians who actively analyze clinical data in collaboration with clinicians, the analyses of the different data sets throughout the book demonstrate how predictive models can be obtained from proper data sets.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    103292005X / 9781032920054

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    EUR 91,80

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    Taschenbuch. Condición: Neu. Neuware - Pattern theory is a distinctive approach to the analysis of all forms of real-world signals. At its core is the design of a large variety of probabilistic models whose samples reproduce the look and feel of the real signals, their patterns, and their variability. Bayesian statistical inference then allows you to apply these models in the analysis of new signals. This book treats the mathematical tools, the models themselves, and the computational algorithms for applying statistics to analyze six representative classes of signals of increasing complexity. The book covers patterns in text, sound, and images. Discussions of images include recognizing characters, textures, nature scenes, and human faces. The text includes online access to the materials (data, code, etc.) needed for the exercises.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032920858 / 9781032920856

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    EUR 91,74

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    Taschenbuch. Condición: Neu. Neuware - Manual of Environmental Management is a practical guide for those involved in the control and reduction of environmental impacts in organisations. This comprehensive and practical guide takes you through the main environmental challenges organisations face and the improvement strategies used to manage them.Chapter by chapter, Manual of Environmental Management discusses the fundamental issues and principles surrounding environmental policy, law and management and provides crucial information on how to respond and implement environmental programmes.This book is the perfect reference tool for the environmental professional and an invaluable study text for those preparing for professional examinations such as the NEBOSH Environmental Diploma and IEMA Associate Membership Exam.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032919094 / 9781032919096

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    Taschenbuch. Condición: Neu. Neuware - Electrochemically Enabled Sustainability: Devices, Materials and Mechanisms for Energy Conversion covers topics related to current research in electrochemical power sources, highlighting some of the latest concepts in electrochemical conversion for sustainability. The book examines the most recent and innovative technologies employed in battery and fuel cell technology. It introduces the fundamental concepts applied to these electrochemical power sources and provides in-depth discussion on the materials, design, and performance of these devices.Written by internationally acclaimed experts, the chapters illustrate how key technologies for sustainability are enabled by electrochemical conversion. Topics include the reduction of carbon dioxide to resolve issues of carbon capture, energy storage, and generation of portable fuel; turning waste into energy using microbial fuel cells; the promise of vanadium redox flow batteries for massive energy storage; and improved performance of hybrid devices. The book addresses numerous aspects of lithium-type batteries for vehicle propulsion and energy storage, presenting a broad range of lithium batteries, and considering nano-structuring issues, layered-structure materials, and hierarchical structure.This book provides timely coverage of critical issues in emerging and conventional technologies, presenting a wide range of electrochemical devices, related materials, and operation mechanisms. It stimulates an appreciation for the novelty of these electrochemical power sources and offers a projection of future integration of these devices in practice.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032930950 / 9781032930954

    Serie: Libro 1 de 5 - Natural Stone and World Heritage

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    EUR 92,25

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    Taschenbuch. Condición: Neu. Neuware - Heritage stones are those stones that have been used for many years, even centuries, to build the historic buildings and monuments of places around the world. Some of these stones are still being used for construction, but others are no longer used, either because quarries were exhausted or closed or because architects and constructors do not know about their particularities and importance. Several scientific papers discuss many of these stones, and a number of papers are currently being prepared, but this book is the first to emphasize the importance and significance of natural stone in the construction of a city, Salamanca, recognized as a World Heritage Site by UNESCO since 1988. In light of this recognition, Salamanca has a duty to preserve all historic buildings that make up the city by restoring those that are starting to deteriorate centuries after their construction. This book describes the buildings, the stones (all quarried centuries ago in the surrounding area), and the stone quarries, some of them inactive for many years, but that should still allow extraction of blocks on demand to restore and replace damaged specimens in the buildings, preserving the very character that saw the city receive recognition by UNESCO in the first place. There are many other places around the world that should follow this initiative and disseminate the importance of their heritage stones. This book will be of interest to professionals and academics in Geology, Engineering, architectural and artistic work in stone, both construction and conservation, but also to the general public.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    0367712660 / 9780367712662

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    Librería: AHA-BUCH GmbH, Einbeck, AlemaniaAHA-BUCH GmbH

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    EUR 92,09

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    Taschenbuch. Condición: Neu. Neuware - The COVID-19 pandemic has disrupted supply chains, hence corporations must devise and realign their policies and strategies accordingly to stay competitive in this dynamic situation. This book provides tools to cope with such a scenario and to make appropriate decisions to come out unscathed.Making Complex Decisions toward Revamping Supply Chains amid COVID-19 Outbreak presents the tools and technologies needed to revamp supply chains challenged by the COVID-19 pandemic. The book presents case studies along with historical perspectives for guidance. It explores the supply chain post-COVID-19, discusses the future scenarios of new and emerging supply chains, and describes various multi-criteria decision-making (MCDM) tools used to make complex decisions so companies can stay ahead. The book also offers domain experts' opinions and views to help organizations formulate real-time strategies.This book is written for researchers, professionals, and undergraduate and postgraduate students to provide an evidence-based cause, effect, and solution after the COVID-19 disaster.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032919310 / 9781032919317

    Serie: Libro 51 de 57 - Frontiers in Neuroscience

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    EUR 91,81

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    Taschenbuch. Condición: Neu. Neuware - Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain.Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer.Composed of contributions from distinguished researchers around the world, the book explores topics such as: - Neuropathic itch - Peripheral neuronal mechanism of itch - The role of PAR-2 in neuroimmune communication and itch - Mrgprs as itch receptors - The role of interleukin-31 and oncostatin M in itch and neuroimmune communication - Spinal coding of itch and pain - Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032923792 / 9781032923796

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    Taschenbuch. Condición: Neu. Neuware - Office ergonomics - whether we realize it or not - directly or indirectly affects every one of us. It is the study of the work we do, the environment we work in, and the tools we use to successfully perform our jobs. Office ergonomics helps us be comfortable and safe at work, which reduces the risk of injury, lowers stress, increases personal engagement, and raises overall work performance. This book embraces and addresses the new reality of the traditional 'office' work, which is ever changing and evolving, and offers tactical recommendations on how to make non-traditional office settings more comfortable.This book suggests how to - Set up the office, wherever that may be - at a company site, at home, at a corner café, on a commuter train - Interact with colleagues - Organize and pace work - Select and arrange equipment and furniture - Maintain the physical climate - lighting, sound, heating and cooling The book is a practical one, based on sound theory and solid research. Written for non-engineers as well as those in the industry, it has a conversational tone, reflects true-life situations that office workers face, and is adaptable to multiple office settings. While budding ergonomists will find it educational, office managers and designers will benefit from it as well. You will find ten fast-paced chapters, augmented with brief case studies and illustrations, and capped off with a series of practical design recommendations. Three appendices delve into ergonomic topics with more thorough details.This book suggests how best to achieve a harmonious work scenario by optimizing the 'fit' between the person and his or her environment. This, in a nutshell, is what ergonomics is all about: working with ease and efficiency.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032917822 / 9781032917825

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    Taschenbuch. Condición: Neu. Neuware - The latest edition of a perennial bestseller, Multistage Separation Processes, Fourth Edition provides a clear and thorough presentation of the theoretical foundation, and understanding of the development, evaluation, design, and optimization steps of these processes, from both an academic and industrial perspective. The book's emphasis on starting with theoretical models and their role in computer simulation, followed by practical applications, sets it apart from other texts on this topic. The author also highlights the importance of relating fundamental concepts to intuitive understanding of the processes.See What's New in the Fourth Edition: - Chapter on fluid-solid operations - Expanded development of theories and methods for many applications - Adds numerous industry-related examples and end-of-chapter problems - Case studies combined with examples - Updated and enhanced figures The book includes a generous number of examples from a wide variety of applications to relate theory to actual results, and to demonstrate the performance of process under varying conditions. The chapter topics follow a logical path that starts with basics and theoretical concepts, and progresses systematically into the various separation processes. Each chapter provides the information relevant to a specific topic, and refers to appropriate chapters in the book as needed. These features combine to give you the understanding required to make the best selections of property prediction and simulation techniques and avoid the cost incurred by the use of improper simulations.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032920289 / 9781032920283

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    Taschenbuch. Condición: Neu. Neuware - Encyclopedic in scope, Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 3: Environmental Manifestations of the Neurocardiovascular Systems draws deeply from clinical histories of thousands of patients. It focuses on clinical syndromes within the musculoskeletal, neurological, and cardiovascular systems with a special focus on vascular dysfunction and heart failure treatment. The book explores mechanisms of chemical sensitivity and chronic degenerative disease, their manifestations, diagnosis, and approaches to reverse dysfunction. It covers a wide variety of topics including environmental sensitivity due to external pollutants, environmental control for reducing total body load, pollutant damage to vascular perfusion, altered blood volume, fluctuations of oxygen extraction, effects of endocrine on the vascular system, effects of pollutants on myocardial cells, and mechanisms in vascular damage.The book also discusses in detail a wide variety of clinical manifestations including vasculitis, cardiac arrhythmias, cardiac metabolic syndrome, myocarditis, atherosclerosis, heart failure, urticaria, and anaphylaxis. Treatment for heart failure is also discussed. The third volume of a five-volume set, the book provides an essential resource for health care providers diagnosing and treating chemical sensitivity and chronic degenerative disease.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032919523 / 9781032919522

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    EUR 92,07

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    Taschenbuch. Condición: Neu. Neuware - Drug discovery for ocular diseases has taken great strides in the last two decades. From cornea to choroid, new drugs have been formulated to address a great variety of ocular diseases. Yet without good drug delivery systems, these drugs are less effective than they might be or could even cause serious side effects. Ocular Drug Delivery Systems: Barriers and Application of Nanoparticulate Systems presents research on the development of currently marketed devices and recent trends in the topical delivery of drugs to the posterior of the eye. With contributions from leading pharmaceutical researchers and industry experts, eye researchers, surgeons, pharmacologists from academia, the National Eye Institute, and leading ophthalmic companies such as Pfizer, Allergan, and Novartis, the book presents the state of the art in the use of nanoparticles in ocular drug delivery systems and also sets the stage for future developments.This volume provides both a current evaluation and a future roadmap for developments in ocular drug delivery. The subjects range from biological needs to material challenges and finally to clinical applications for improving drug delivery for conditions where treatments already exist. It also explores areas where effective drugs may be currently available but yet need a safe, efficient, and efficacious delivery vehicle.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032921390 / 9781032921396

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    Taschenbuch. Condición: Neu. Neuware - Decision makers are often faced with several conflicting alternatives. How do they evaluate trade-offs when there are more than three criteria To help people make optimal decisions, scholars in the discipline of multiple criteria decision making (MCDM) continue to develop new methods for structuring preferences and determining the correct relative weights for criteria. A compilation of modern decision-making techniques, Multiple Attribute Decision Making: Methods and Applications focuses on the fuzzy set approach to multiple attribute decision making (MADM). Drawing on their experience, the authors bring together current methods and real-life applications of MADM techniques for decision analysis. They also propose a novel hybrid MADM model that combines DEMATEL and analytic network process (ANP) with VIKOR procedures.The first part of the book focuses on the theory of each method and includes examples that can be calculated without a computer, providing a complete understanding of the procedures. Methods include the analytic hierarchy process (AHP), ANP, simple additive weighting method, ELECTRE, PROMETHEE, the gray relational model, fuzzy integral technique, rough sets, and the structural model. Integrating theory and practice, the second part of the book illustrates how methods can be used to solve real-world MADM problems. Applications covered in the book include: - AHP to select planning and design services for a construction project - TOPSIS and VIKOR to evaluate the best alternative-fuel vehicles for urban areas - ELECTRE to solve network design problems in urban transportation planning - PROMETEE to set priorities for the development of new energy systems, from solar thermal to hydrogen energy - Fuzzy integrals to evaluate enterprise intranet web sites - Rough sets to make decisions in insurance marketing Helping readers understand how to apply MADM techniques to their decision making, this book is suitable for undergraduate and graduate students as well as practitioners.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032920335 / 9781032920337

    Serie: Libro 54 de 57 - Frontiers in Neuroscience

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    Taschenbuch. Condición: Neu. Neuware - Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: - Epidemiology - Pathophysiology - Diagnosis - Current treatment strategies and sequelae - Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032922680 / 9781032922683

    Serie: Libro 24 de 50 - Chapman & Hall/CRC Computational Biology Series

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    Taschenbuch. Condición: Neu. Neuware - While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL mapping. After introducing basic genetics topics and statistical principles, the author discusses the principles of quantitative genetics, general statistical issues of QTL mapping, commonly used one-dimensional QTL mapping approaches, and multiple interval mapping methods. He then explains how to use a feature selection approach to tackle a QTL mapping problem with dense markers. The book also provides comprehensive coverage of Bayesian models and MCMC algorithms and describes methods for multi-trait QTL mapping and eQTL mapping, including meta-trait methods and multivariate sequential procedures.This book emphasizes the modern statistical methodology for QTL mapping as well as the statistical issues that arise during this process. It gives the necessary biological background for statisticians without training in genetics and, likewise, covers statistical thinking and principles for geneticists. Written primarily for geneticists and statisticians specializing in QTL mapping, the book can also be used as a supplement in graduate courses or for self-study by PhD students working on QTL mapping projects.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032924675 / 9781032924670

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    Taschenbuch. Condición: Neu. Neuware - Microscopy is at the forefront of multidisciplinary research. It was developed by physicists, made specific by chemists, and applied by biologists and doctors to better understand how the human body works. For this very reason, the field has been revolutionized in past decades.The objective of Optical Nanoscopy and Novel Microscopy Techniques is to choose some of those revolutionary ideas and serve a general audience from broad disciplines to achieve a fundamental understanding of these technologies and to better apply them in their daily research.The book begins with coverage of super-resolution optical microscopy, which discusses targeted modulation such as STED and SIM or localization methods such as PALM. It then discusses novel development of fluorescent probes, such as organic small-molecule probes, fluorescent proteins, and inorganic labels such as quantum dots. Finally, it describes advanced optical microscopy, such as fluorescence lifetime imaging, fiber optic microscopy, scanning ion conductance microscopy, and the joining of optics and acoustics-photoacoustic microscopy. Following each chapter, a detailed list of references is provided. Problems at the end of each chapter are also included.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032920270 / 9781032920276

    Serie: Libro 55 de 57 - Frontiers in Neuroscience

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    Taschenbuch. Condición: Neu. Neuware - Statistical Techniques for Neuroscientists introduces new and useful methods for data analysis involving simultaneous recording of neuron or large cluster (brain region) neuron activity. The statistical estimation and tests of hypotheses are based on the likelihood principle derived from stationary point processes and time series. Algorithms and software development are given in each chapter to reproduce the computer simulated results described therein.The book examines current statistical methods for solving emerging problems in neuroscience. These methods have been applied to data involving multichannel neural spike train, spike sorting, blind source separation, functional and effective neural connectivity, spatiotemporal modeling, and multimodal neuroimaging techniques. The author provides an overview of various methods being applied to specific research areas of neuroscience, emphasizing statistical principles and their software. The book includes examples and experimental data so that readers can understand the principles and master the methods.The first part of the book deals with the traditional multivariate time series analysis applied to the context of multichannel spike trains and fMRI using respectively the probability structures or likelihood associated with time-to-fire and discrete Fourier transforms (DFT) of point processes. The second part introduces a relatively new form of statistical spatiotemporal modeling for fMRI and EEG data analysis. In addition to neural scientists and statisticians, anyone wishing to employ intense computing methods to extract important features and information directly from data rather than relying heavily on models built on leading cases such as linear regression or Gaussian processes will find this book extremely helpful.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032924594 / 9781032924595

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    Taschenbuch. Condición: Neu. Neuware - The inverse design approach is new to the built environment research and design community, though it has been used in other industries including automobile and airplane design. This book, from some of the pioneers of inverse design applications in the built environment, introduces the basic principles of inverse design and the specific techniques that can be applied to built environment systems. The authors' inverse design concept uses the desired enclosed environment as the design objective and inversely determines the systems required to achieve the objective. The book discusses a number of backward and forward methods for inverse design. Backward methods, such as the quasi-reversibility method, the pseudo-reversibility method, and the regularized inverse matrix method, can be used to identify contaminant sources in an enclosed environment. However, these methods cannot be used to inversely design a desired indoor environment. Forward methods, such as the computational-fluid-dynamics (CFD)-based genetic algorithm (GA) method, the CFD-based adjoint method, the CFD-based artificial neural network (ANN) method, and the CFD-based proper orthogonal decomposition (POD) method, show the promise in the inverse design of airflow and heat transfer in an enclosed environment. The book describes the fundamentals of the methods for beginners, provides exciting design examples for the reader to duplicate, discusses the pros and cons of each design method and points out the knowledge gaps for further development.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032917687 / 9781032917689

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    Taschenbuch. Condición: Neu. Neuware - Ultrasonic irradiation and the associated sonochemical and sonophysical effects are complementary techniques for driving more efficient chemical reactions and yields. Sonochemistry-the chemical effects and applications of ultrasonic waves-and sustainable (green) chemistry both aim to use less hazardous chemicals and solvents, reduce energy consumption, and increase product selectivity. A comprehensive collection of knowledge, Handbook on Applications of Ultrasound covers the most relevant aspects linked to and linking green chemistry practices to environmental sustainability through the uses and applications of ultrasound-mediated and ultrasound-assisted biological, biochemical, chemical, and physical processes. Chapters are presented in the areas of: - Medical applications - Drug and gene delivery - Nanotechnology - Food technology - Synthetic applications and organic chemistry - Anaerobic digestion - Environmental contaminants degradation - Polymer chemistry - Industrial syntheses and processes - Reactor design - Electrochemical systems - Combined ultrasound-microwave technologies While the concepts of sonochemistry have been known for more than 80 years, in-depth understanding of this phenomenon continues to evolve. Through a review of the current status of chemical and physical science and engineering in developing more environmentally friendly and less toxic synthetic processes, this book highlights many existing applications and the enormous potential of ultrasound technology to upgrade present industrial, agricultural, and environmental processes.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032921161 / 9781032921167

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    Taschenbuch. Condición: Neu. Neuware - Governments across the globe are setting targets for reducing their carbon emissions. For example, the UK Government has committed to an eighty per cent reduction by 2050, when twenty-eight million buildings that currently exist will still be standing; this represents a challenge to improve the energy efficiency of more than one building per minute between now and 2050! This is a problem that needs tackling worldwide and is a challenge to both the refurbishment sector of the global construction industry and to those who own and operate existing buildings.Sustainable Retrofit and Facilities Management provides comprehensive guidance to those involved in the refurbishment and management of existing buildings on minimizing carbon emissions, water consumption and waste to landfill, along with enhancing the long term sustainability of a building. Practical guidance is provided on measures that can be used to improve the efficiency and sustainability of existing buildings, through both good management and refurbishment. Also explored is the relationship between the refurbishment of existing buildings, facility management and the wider community infrastructure. The book looks at management tools such as post occupancy evaluation, building health checks, energy management software, green building management toolkits and green leases. Illustrated throughout with case studies and examples of best practice, this is a must-have handbook for engineers, architects, developers, contractors and facility managers.…

  • Idioma: Inglés

    Editorial: CRC Press Okt 2024, 2024

    1032926945 / 9781032926940

    Serie: Libro 46 de 110 - ISSN

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    Taschenbuch. Condición: Neu. Neuware - Drawing on the authors' substantial expertise in modeling longitudinal and clustered data, Quasi-Least Squares Regression provides a thorough treatment of quasi-least squares (QLS) regression-a computational approach for the estimation of correlation parameters within the framework of generalized estimating equations (GEEs). The authors present a detailed evaluation of QLS methodology, demonstrating the advantages of QLS in comparison with alternative methods. They describe how QLS can be used to extend the application of the traditional GEE approach to the analysis of unequally spaced longitudinal data, familial data, and data with multiple sources of correlation. In some settings, QLS also allows for improved analysis with an unstructured correlation matrix. Special focus is given to goodness-of-fit analysis as well as new strategies for selecting the appropriate working correlation structure for QLS and GEE. A chapter on longitudinal binary data tackles recent issues raised in the statistical literature regarding the appropriateness of semi-parametric methods, such as GEE and QLS, for the analysis of binary data; this chapter includes a comparison with the first-order Markov maximum-likelihood (MARK1ML) approach for binary data.Examples throughout the book demonstrate each topic of discussion. In particular, a fully worked out example leads readers from model building and interpretation to the planning stages for a future study (including sample size calculations). The code provided enables readers to replicate many of the examples in Stata, often with corresponding R, SAS, or MATLAB® code offered in the text or on the book's website.…