Crc press okt 2019 (128 resultados)

Taschenbuch. Condición: Neu. Neuware - Wondrous One Sheet Origami is a how-to book full of beautiful origami designs covering a wide range of folding levels from simple to high intermediate, with more emphasis on the latter. The book is meant for audiences 12 years of age and above, and children folding at higher than age level. Most of the designs are flat and suitable for mounting on cards or framing as gifts.Features¿ Richly illustrated full-color book with clear, crisp diagrams following international standard, and an abundance of photographs of finished models¿ Select designs hand-picked by the author based on social media responses¿ Most of the designs incorporate color-change, a technique showing both sides of paper for enhanced beauty.…

Taschenbuch. Condición: Neu. Neuware - With the maturation of laser technology in diagnostic and conservation applications, conservation scientists, archeologists, art historians, researchers, and advanced science-oriented students now have the tools necessary for preserving the future of our past-our cultural heritage. Presenting recent developments in the field, Lasers in the Preservation of Cultural Heritage: Principles and Applications addresses the basic concepts of laser applications and supplies case studies of analytical, structural diagnostic, and laser cleaning applications. The book provides a comprehensive presentation of the fundamental principles and applications of modern laser technology in the analysis of composition, diagnostics of structural integrity, and conservation of artworks and antiquities.Beginning with an introduction to the basic techniques used in art conservation and archeology, the book describes the fundamental aspects of laser-matter interactions, emphasizing laser diagnostics and laser processing applications. The next few chapters focus on laser-based spectroscopic techniques for the analysis of the composition of materials in art and archaeology, including laser-induced breakdown, Raman, and laser-induced fluorescence spectroscopic techniques. The book proceeds to highlight nondestructive diagnostic techniques, laser processing applications, laser applications for the cleaning of paintings and stone, and methods for the removal of encrustations. It concludes with case studies for the conservation of materials like parchment, paper, metal, ivory, and wood, and includes conservation approaches for modern paintings.Bridging science with art, Lasers in the Preservation of Cultural Heritage presents a systematic overview of the fundamentals and applications of laser techniques in artwork conservation and archeological science.…

Taschenbuch. Condición: Neu. Neuware - Answering a long-standing need in the pharmaceutical and biotechnology fields, this definitive reference focuses on the biology, pharmacology, and therapeutic applications of endogenous peptide mediators and their analogues. It takes peptide science beyond chemical synthesis strategies and into the realms of peptide biology and therapeutics. It presents the overall contribution peptide science has made to molecular, cellular, and whole organism biology, while discussing future targets and therapeutic applications. With the mounting worldwide interest in the therapeutic potential of peptides, this is an indispensable work for researchers.…

Taschenbuch. Condición: Neu. Neuware - Despite the existence of two barrier systems in the brain, research over the last century has mostly focused on the blood-brain barrier rather than on the blood-CSF barrier. Today, there is a greater understanding of the function of the blood-CSF barrier and of the choroid plexus, a tissue that is the primary site of this barrier. With the growing number of studies that focus on the role of the blood-CSF barrier in CNS homeostasis and neurological disorders, a modern overview of the blood-CSF barrier is long overdue.The Blood-Cerebrospinal Fluid Barrier is exclusively devoted to the blood-CSF barrier. Internationally renowned experts discuss the most recent progress in the field of choroid plexus physiology and update our knowledge of the function of the blood-CSF barrier. The book begins with an overview of the development and morphology of the choroid plexus, and then covers various aspects of its function, such as the regulation of choroidal blood flow, ion transport, and the production and transport of polypeptides. Following an extensive section on the role of the choroid plexus in CNS disorders, the final section discusses in vitro, in vivo, and in situ models of the blood-CSF barrier.This unique book analyzes a wealth of new research on the proven and potential roles of the choroid plexus/blood-CSF barrier in the brain. It is a valuable resource that will foster future studies in neuroscience, pharmacology, and toxicology.…

Taschenbuch. Condición: Neu. Neuware - This unique reference examines the modern pharmaceutical compacting techniques used to form tablets out of powders-describing the physical structure of pharmaceutical compacts, the bonding phenomena that occur during powder compaction, and the compression mechanisms of pharmaceutical particles.…

Taschenbuch. Condición: Neu. Neuware - These proceedings of EXPLOMET 90, the International Conference on the Materials Effects of Shock-Wave and High-Strain-Rate Phenomena, held August 1990, in La Jolla, California, represent a global and up-to-date appraisal of this field. Contributions (more than 100) deal with high-strain-rate deforma.…

Taschenbuch. Condición: Neu. Neuware - There is an ongoing data explosion transpiring that will make previous creations, collections, and storage of data look trivial. Big Data, Mining, and Analytics: Components of Strategic Decision Making ties together big data, data mining, and analytics to explain how readers can leverage them to extract valuable insights from their data. Facilitating a clear understanding of big data, it supplies authoritative insights from expert contributors into leveraging data resources, including big data, to improve decision making. Illustrating basic approaches of business intelligence to the more complex methods of data and text mining, the book guides readers through the process of extracting valuable knowledge from the varieties of data currently being generated in the brick and mortar and internet environments. It considers the broad spectrum of analytics approaches for decision making, including dashboards, OLAP cubes, data mining, and text mining. - Includes a foreword by Thomas H. Davenport, Distinguished Professor, Babson College; Fellow, MIT Center for Digital Business; and Co-Founder, International Institute for Analytics - Introduces text mining and the transforming of unstructured data into useful information - Examines real time wireless medical data acquisition for today's healthcare and data mining challenges - Presents the contributions of big data experts from academia and industry, including SAS - Highlights the most exciting emerging technologies for big data Filled with examples that illustrate the value of analytics throughout, the book outlines a conceptual framework for data modeling that can help you immediately improve your own analytics and decision-making processes. It also provides in-depth coverage of analyzing unstructured data with text mining methods.…

Taschenbuch. Condición: Neu. Neuware - A compilation of the fundamental knowledge, skills, techniques, and tools require by all security professionals, Information Security Handbook, Sixth Edition sets the standard on which all IT security programs and certifications are based. Considered the gold-standard reference of Information Security, Volume 2 includes coverage of each domain of the Common Body of Knowledge, the standard of knowledge required by IT security professionals worldwide. In step with the lightening-quick, increasingly fast pace of change in the technology field, this book is updated annually, keeping IT professionals updated and current in their field and on the job.…

Taschenbuch. Condición: Neu. Neuware - Face detection and recognition are the nonintrusive biometrics of choice in many security applications. Examples of their use include border control, driver's license issuance, law enforcement investigations, and physical access control.Face Detection and Recognition: Theory and Practice elaborates on andexplains the theory and practice of face detection and recognition systems currently in vogue. The book begins with an introduction to the state of the art, offering a general review of the available methods and an indication of future research using cognitive neurophysiology. The text then: - Explores subspace methods for dimensionality reduction in face image processing, statistical methods applied to face detection, and intelligent face detection methods dominated by the use of artificial neural networks - Covers face detection with colour and infrared face images, face detection in real time, face detection and recognition using set estimation theory, face recognition using evolutionary algorithms, and face recognition in frequency domain - Discusses methods for the localization of face landmarks helpful in face recognition, methods of generating synthetic face images using set estimation theory, and databases of face images available for testing and training systems - Features pictorial descriptions of every algorithm as well as downloadable source code (in MATLAB®/PYTHON) and hardware implementation strategies with code examples - Demonstrates how frequency domain correlation techniques can be used supplying exhaustive test results Face Detection and Recognition: Theory and Practice provides students, researchers, and practitioners with a single source for cutting-edge information on the major approaches, algorithms, and technologies used in automated face detection and recognition.…

Taschenbuch. Condición: Neu. Neuware - In the last few decades, significant advancements in the biology and engineering of stem cells have enabled progress in their clinical application to revascularization therapies. Some strategies involve the mobilization of endogenous stem cell populations, and others employ cell transplantation. However, both techniques have benefited from multidisciplinary efforts to create biomaterials and other biomedical tools that can improve and control the fate of stem cells, and advance our understanding of them.Stem Cells and Revascularization Therapies focuses on the fundamentals and applied studies in stem cell biology, and provides perspectives associated with the development of revascularization strategies. To help readers understand the multidisciplinary issues associated with this topic, this book has been divided into four sections: - Section 1: Explores how to define, isolate, and characterize various stem and progenitor cell populations for neovascularization - Section 2: Summarizes some especially useful model systems and approaches used to regulate angiogenesis, vasculogenesis, and arteriogenesis, and explores their impact on formation of functional vessels in vivo - Section 3: Focuses on stem cell homing to sites of injury and inflammation, as well as strategies to exploit this mobilization phenomenon - Section 4: Covers stem cell transplantation topics, including recreating features of endogenous stem cell niches to maintain the multipotency of transplanted cells and combinatorial delivery of cells and molecular factors Intended to inspire new contributions to improve the therapeutic efficacy, Stem Cells and Revascularization Therapies outlines emergent findings and challenges regarding the use of stem cells in revascularization therapies. Overcoming the significant.…

Taschenbuch. Condición: Neu. Neuware - A Thorough Overview of the Next Generation in ComputingPoised to follow in the footsteps of the Internet, grid computing is on the verge of becoming more robust and accessible to the public in the near future. Focusing on this novel, yet already powerful, technology, Introduction to Grid Computing explores state-of-the-art grid projects, core grid technologies, and applications of the grid.After comparing the grid with other distributed systems, the book covers two important aspects of a grid system: scheduling of jobs and resource discovery and monitoring in grid. It then discusses existing and emerging security technologies, such as WS-Security and OGSA security, as well as the functions of grid middleware at a conceptual level. The authors also describe famous grid projects, demonstrate the pricing of European options through the use of the Monte Carlo method on grids, and highlight different parallelization possibilities on the grid.Taking a tutorial approach, this concise book provides a complete introduction to the components of the grid architecture and applications of grid computing. It expertly shows how grid computing can be used in various areas, from computational mechanics to risk management in financial institutions. …

Taschenbuch. Condición: Neu. Neuware - The only guide to focus primarily on current molecular methods of diagnosis and early stage evaluation, this reference presents the latest techniques and technologies for dementia identification and evaluation, including neuropathological strategies, neuropsychological tests, biomarkers, CT, MRI, functional MRI, PET, and SPECT. Offering practical care and examination guidelines, each chapter provides findings that are particularly relevant for the assessment of disorders such as Alzheimer's disease, dementia with Lewy bodies, vascular dementia, and fronto-temporal dementia. …

Taschenbuch. Condición: Neu. Neuware - Industrial Applications of High-Performance Computing: Best Global Practices offers a global overview of high-performance computing (HPC) for industrial applications, along with a discussion of software challenges, business models, access models (e.g., cloud computing), public-private partnerships, simulation and modeling, visualization, big data analysis, and governmental and industrial influence. Featuring the contributions of leading experts from 11 different countries, this authoritative book: - Provides a brief history of the development of the supercomputer - Describes the supercomputing environments of various government entities in terms of policy and service models - Includes a case study section that addresses more subtle and technical aspects of industrial supercomputing - Shows how access to supercomputing matters, and how supercomputing can be used to solve large-scale and complex science and engineering problems - Emphasizes the need for collaboration between companies, political organizations, government agencies, and entire nations Industrial Applications of High-Performance Computing: Best Global Practices supplies computer engineers and researchers with a state-of-the-art supercomputing reference. This book also keeps policymakers and industrial decision-makers informed about the economic impact of these powerful technological investments.…

Taschenbuch. Condición: Neu. Neuware - These are exciting times for the field of optical imaging of brain function. Rapid developments in theory and technology continue to considerably advance understanding of brain function. Reflecting changes in the field during the past five years, the second edition of In Vivo Optical Imaging of Brain Function describes state-of-the-art techniques and their applications for the growing field of functional imaging in the live brain using optical imaging techniques.New in the Second Edition: - Voltage-sensitive dyes imaging in awake behaving animals - Imaging based on genetically encoded probes - Imaging of mitochondrial auto-fluorescence as a tool for cortical mapping - Using pH-sensitive dyes for functional mapping - Modulated imaging - Calcium imaging of neuronal activity using 2-photon microscopy - Fourier approach to optical imaging - Fully updated chapters from the first edition Leading Authorities Explore the Latest Techniques Updated to reflect continuous development in this emerging research area, this new edition, as with the original, reaches across disciplines to review a variety of non-invasive optical techniques used to study activity in the living brain. Leading authorities from such diverse areas as biophysics, neuroscience, and cognitive science present a host of perspectives that range from a single neuron to large assemblies of millions of neurons, captured at various temporal and spatial resolutions. Introducing techniques that were not available just a few years ago, the authors describe the theory, setup, analytical methods, and examples that highlight the advantages of each particular method.…

Taschenbuch. Condición: Neu. Neuware - Shadow Algorithms Data Miner provides a high-level understanding of the complete set of shadow concepts and algorithms, addressing their usefulness from a larger graphics system perspective. It discusses the applicability and limitations of all the direct illumination approaches for shadow generation.With an emphasis on shadow fundamentals, the book gives an organized picture of the motivations, complexities, and categorized algorithms available to generate digital shadows. It helps readers select the most relevant algorithms for their needs by placing the shadow algorithms in real-world contexts and looking at them from a larger graphics system perspective. As a result, readers know where to start for their application needs, which algorithms to begin considering, and which papers and supplemental material should be consulted for further details.…

Taschenbuch. Condición: Neu. Neuware - In the U.S. alone, severe food-related allergic reactions account for an estimated 30,000 emergency room visits and 150 deaths per year - unsettling statistics for food product developers and manufacturers who are charged with ensuring food safety and quality throughout the entire farm-to-table production chain. Providing the clear-cut information necessary to conduct an effective allergen risk analysis, Chemical and Biological Properties of Food Allergens comprehensively examines the chemical, analytical, technological, and medical aspects of food allergies and the growing problem of cross-contact contamination during product processing.With contributions from an international team of research specialists, the book explains the basic mechanisms of allergenic reactions in humans, the molecular background of these mechanisms, and the problems of food tolerance and intolerance. It also discusses the issues related to common treatments of food allergies and the narrow groups into which they are categorized. Covering the most important recognized allergens in the U.S. and the EU, this resource also explores cutting-edge technological and biotechnological ways to lower the immuno-reactive and allergenic properties of foods. Chemical and Biological Properties of Food Allergens evaluates the current research literature in a concise format - a must for food product developers and biochemists.…

Taschenbuch. Condición: Neu. Neuware - Exploring theories and applications developed during the last 30 years, Digital Geometry in Image Processing presents a mathematical treatment of the properties of digital metric spaces and their relevance in analyzing shapes in two and three dimensions. Unlike similar books, this one connects the two areas of image processing and digital geometry, highlighting important results of digital geometry that are currently used in image analysis and processing.The book discusses different digital geometries in multi-dimensional integral coordinate spaces. It also describes interesting properties of the geometries, including metric and topological properties, shapes of circles and spheres, proximity to Euclidean norms, and number theoretic representations of geometric objects such as straight lines and circles. The authors-all active researchers in image processing and digital geometry-demonstrate how these concepts and properties are useful in various techniques for image processing and analysis. In particular, the book covers applications in object representation and shape analysis.With many figures (some in color) and end-of-chapter exercises, this book provides an in-depth, unified account of digital metrics, the characterization of digital curves and straight lines, and their uses in shape analysis. It gives you insight on the latest two- and three-dimensional image processing applications.…

Taschenbuch. Condición: Neu. Neuware - The typical computational approach to object understanding derives shape information from the 2D outline of the objects. For complex object structures, however, such a planar approach cannot determine object shape; the structural edges have to be encoded in terms of their full 3D spatial configuration. Computer Vision: From Surfaces to 3D Objects is the first book to take a full approach to the challenging issue of veridical 3D object representation. It introduces mathematical and conceptual advances that offer an unprecedented framework for analyzing the complex scene structure of the world.An Unprecedented Framework for Complex Object RepresentationPresenting the material from both computational and neural implementation perspectives, the book covers novel analytic techniques for all levels of the surface representation problem. The cutting-edge contributions in this work run the gamut from the basic issue of the ground plane for surface estimation through mid-level analyses of surface segmentation processes to complex Riemannian space methods for representing and evaluating surfaces.State-of-the-Art 3D Surface and Object RepresentationThis well-illustrated book takes a fresh look at the issue of 3D object representation. It provides a comprehensive survey of current approaches to the computational reconstruction of surface structure in the visual scene.…

Taschenbuch. Condición: Neu. Neuware - Drawing on the authors' more than six years of R&D in location-based information systems (LBIS) as well as their participation in defining the Java ME Location API 2.0, Location-Based Information Systems: Developing Real-Time Tracking Applications provides information and examples for creating real-time LBIS based on GPS-enabled cellular phones. Each chapter presents a general real-time tracking system example that can be easily adapted to target any application domain and that can incorporate other sensor data to make the system 'participatory sensing' or 'human-centric sensing.'The book covers all of the components needed to develop an LBIS. It discusses cellular phone programming using the Java ME platform, positioning technologies, databases and spatial databases, communications, client- and server-side data processing, and real-time data visualization via Google Maps and Google Earth. Using freely available software, the authors include many code examples and detailed instructions for building your own system and setting up your entire development environment. Web ResourceA companion website at csee.usf.edu/~labrador/LBIS provides additional information and supporting material. It contains all of the software packages and applications used in the text as well as PowerPoint slides and laboratory examples.Although LBIS applications are still in the beginning stages, they have the potential to transform our daily lives, from warning us about possible health problems to monitoring pollution levels around us. Exploring this novel technology, Location-Based Information Systems describes the technical components needed to create location-based services with an emphasis on nonproprietary, freely available solutions that work across different technologies and platforms.…

Taschenbuch. Condición: Neu. Neuware - This book provides the connection between the growing body of literature on sustainability and the topics of energy and ICT. It aims to show how stakeholders active in this area need to play their part ensuring that the ICT-sector evolves towards a sector that can lead through 'greening by IT' and also shows that it can 'green its own IT' as well. This is the first book that integrates two seemingly incompatible approaches to sustainability: efficiency and effectiveness. The book builds on the efficiency initiatives already taken by industry, but it is not a 'how-to-do-it manual'. It offers insight in state of the art approaches to green IT and greening by IT. Attention to important stakeholders outside the sector, e.g. policy makers and the field of education, makes this book comprehensive. A more encompassing view on ICT and sustainability is offered to the reader and, as such, managers in higher education, educators, CIO's, policymakers and regulators are inspired to integrate their efforts and to contribute to a transition of one of the most important and prominent sectors in our global economy.…

Taschenbuch. Condición: Neu. Neuware - Although many books have been written on computational fluid dynamics (CFD) and many written on combustion, most contain very limited coverage of the combination of CFD and industrial combustion. Furthermore, most of these books are written at an advanced academic level, emphasize theory over practice, and provide little help to engineers who need to use CFD for combustion modeling.Computational Fluid Dynamics in Industrial Combustion fills this gap in the literature. Focusing on topics of interest to the practicing engineer, it codifies the many relevant books, papers, and reports written on this combined subject into a single, coherent reference. It looks at each topic from a somewhat narrow perspective to see how that topic affects modeling in industrial combustion. The editor and his team of expert authors address these topics within three main sections:Modeling Techniques-The basics of CFD modeling in combustionIndustrial Applications-Specific applications of CFD in the steel, aluminum, glass, gas turbine, and petrochemical industriesAdvanced Techniques-Subjects rarely addressed in other texts, including design optimization, simulation, and visualizationRapid increases in computing power and significant advances in commercial CFD codes have led to a tremendous increase in the application of CFD to industrial combustion. Thorough and clearly representing the techniques and issues confronted in industry, Computational Fluid Dynamics in Industrial Combustion will help bring you quickly up to date on current methods and gain the ability to set up and solve the various types of problems you will encounter.…

Taschenbuch. Condición: Neu. Neuware -Wondrous One Sheet Origami is a how-to book full of beautiful origami designs covering a wide range of folding levels from simple to high intermediate, with more emphasis on the latter. The book is meant for audiences 12 years of age and above, and children folding at higher than age level. Most of the designs are flat and suitable for mounting on cards or framing as gifts.Features¿ Richly illustrated full-color book with clear, crisp diagrams following international standard, and an abundance of photographs of finished models¿ Select designs hand-picked by the author based on social media responses¿ Most of the designs incorporate color-change, a technique showing both sides of paper for enhanced beauty 164 pp. Englisch.…

Taschenbuch. Condición: Neu. Neuware - The product of 20 years of research, this book covers topics in soft tissue elasticity in vivo, from measurement techniques to clinical applications. It provides, for the first time, a single source that systematically introduces the various techniques for in vivo measurement of soft tissue elasticity in an effort to ease the difficulty between learning technical details and clinical applications of techniques.Measurement of Soft Tissue Elasticity in Vivo: Techniques and Applications presents an overview of the existing measurement methods, their physical principles, assumptions, advantages, and disadvantages. Clinical applications discussed include assessment of tissue fibrosis after radiotherapy, articular cartilage degeneration, muscle contraction, cancer staging, liver fibrosis progression, diabetic foot ulceration, cornea stiffening, and wound healing. Techniques covered include shear wave propagation methods, vibro-ultrasound methods, dynamic holography, ultrasound and other indentation methods, and OCT-based and other suction measurement methods.The book also proposes two critical directions for future research in the field. One is to standardize the terms, parameters, and test protocols used in different fields. The second proposal is to standardize one technique to dominate the field, while devices can be adapted to fit the measuring requirements of different tissues. In doing so, the results obtained for the same tissue by different clinicians can be comparable and a standardized protocol can be established.This book bridges the gap between the complexity of measuring techniques and simplicity and accuracy of their clinical use. Its comprehensiveness and clarity help new engineers in the field develop analytical methods and allow clinicians to use these techniques in their practice with greater confidence.…

Taschenbuch. Condición: Neu. Neuware - Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing paradigms and biomimetic artifacts for chemical sensing. The implications of these findings are relevant to a wide audience, including researchers in artifical olfaction, neuroscientists, physiologists, and scientists working with chemical sensors.Developing neuromorphic olfaction from conceptual points of view to practical applications, this cross-disciplinary book examines: - The biological components of vertebrate and invertebrate chemical sensing systems - The early coding pathways in the biological olfactory system, showing how nonspecific receptor populations may have significant advantages in encoding odor intensity as well as odor identity - The redundancy and the massive convergence of the olfactory receptor neurons to the olfactory bulb - A neuromorphic approach to artificial olfaction in robots - Reactive and cognitive search strategies for olfactory robots - The implementation of a computational model of the mammalian olfactory system The book's primary focus is on translating aspects of olfaction into computationally practical algorithms. These algorithms can help us understand the underlying behavior of the chemical senses in biological systems. They can also be translated into practical applications, such as robotic navigation and systems for uniquely detecting chemical species in a complex background.…

Taschenbuch. Condición: Neu. Neuware - In the medical imaging field, clinicians and researchers are increasingly moving from the qualitative assessment of printed images to the quantitative evaluation of digital images since the quantitative techniques often improve diagnostic accuracy and complement clinical assessments by providing objective criteria. Despite this growing interest, the field lacks a comprehensive body of knowledge. Filling the need for a complete manual on these novel techniques, Quantifying Morphology and Physiology of the Human Body Using MRI presents a wide range of quantitative MRI techniques to study the morphology and physiology of the whole body, from the brain to musculoskeletal systems.Illustrating the growing importance of quantitative MRI, the book delivers an indispensable reference for readers who would like to explore in vivo MRI techniques to quantify changes in the morphology and physiology of tissues caused by various disease mechanisms. With internationally renowned experts sharing their insight on the latest developments, the book goes beyond conventional MRI contrast mechanisms to include new techniques that measure electromagnetic and mechanical properties of tissues.Each chapter offers comprehensive information on data acquisition, processing, and analysis techniques as well as clinical applications. The text organizes the techniques based on their primary use either in the brain or the body. Some of the techniques, such as diffusion-weighted imaging and diffusion tensor imaging, span several application areas, including brain imaging, cancer imaging, and musculoskeletal imaging. The book also covers up-and-coming quantitative techniques that explore tissue properties other than the presence of protons (or other MRI-observable nuclei) and their interactions with their environment. These novel techniques provide unique information about the electromagnetic and mechanical properties of tissues and introd.…

Taschenbuch. Condición: Neu. Neuware - Neuronal communication forms the basis for all behavior, from the smallest movement to our grandest thought processes. Among the many mechanisms that support these functions, spike timing is among the most powerful and-until recently-perhaps the least studied. In the last two decades, however, the study of spike timing has exploded. The heightened interest is due to several factors. These include the development of physiological tools for measuring the activity of neural ensembles and analytical tools for assessing and characterizing spike timing. These advances are coupled with a growing appreciation of spike timing's theoretical importance for the design principles of the brain.Spike Timing: Mechanisms and Function examines the function of spike timing in sensory, motor, and integrative processes, providing readers with a broad perspective on how spike timing is produced and used by the nervous system. It brings together the work and ideas of leaders in the field to address current thinking as well as future possibilities. The first section of the book describes the foundation for quantitative analysis and theory. It examines the information contained in spike timing, how it can be quantified, and how neural systems can extract it. The second section explores how input-output relationships are reflected in spike timing across a range of sensory systems.Drawing together multiple perspectives, including theoretical and computational studies as well as experimental studies in a range of model systems, the book provides a firm background for investigators to consider spike timing as it applies to their own work. It also offers a glimpse of future advances related to mechanisms of spike timing and its role in neural function, such as the development of novel computational technologies. …

Taschenbuch. Condición: Neu. Neuware - Developments in mesoporous ceramics in drug delivery, nanomedicine, and bone tissue regeneration have opened promising developments in biomedical research, many applicable in the clinic in the near future. Due to the ability to fine-tune the physicochemical properties of these materials, the field has experienced an impressive burst in the number of publications. As controlled drug delivery systems are one of the most promising applications for human health care, it is now necessary to set the milestones of this technology, from the very basic to the most advanced.Biomedical Applications of Mesoporous Ceramics: Drug Delivery, Smart Materials and Bone Tissue Engineering is a comprehensive overview of silica-based mesoporous materials with special attention given to their use in drug delivery systems, sophisticated stimuli-responsive materials, and bone tissue engineering. The book provides a comprehensive overview of the basic aspects of the properties of mesoporous materials, with a focus on textural properties such as surface and porosity. Starting from this consolidated knowledge, it then addresses various aspects of more sophisticated stimuli-responsive materials and bone tissue engineering, detailing the research and development of these biomedical applications.…

Taschenbuch. Condición: Neu. Neuware - The unprecedented potential of nanotechnology for early detection, diagnosis, and personalized treatment of diseases has found application in every biomedical imaging modality. However, with the increasing concern about the ethical and toxicity issues associated with some 'nanoplatforms,' biomedical researchers are in pursuit of safer, more precise, and effective ways to practice nanomedicine. Designed and written to be accessible to anyone, with or without previous knowledge of nanotechnology, Nanomedicine: A Soft Matter Perspective takes a balanced look at potential pitfalls and challenges faced by the field and how they can be translated into nonomedicine technologies.A multidisciplinary and fast-evolving research area, nanomedicine presents new clinically relevant promises grounded in the disciplines of molecular biology, genomics, chemistry, and nanotechnology. Nanoparticle-based theranostic approaches have emerged as an interdisciplinary area, which shows promise to understand the components, processes, dynamics, and therapies of a disease at a molecular level. This book discusses some of the unique opportunities presented by biomaterials at the nanoscale. The book provides a broad introduction to the areas of nanomedicinal application with an emphasis on imaging and therapeutics. It covers 'soft' nanoscopic objects with prerequisite features for different imaging modalities with a potential for image-guided drug delivery. The book also offers a general introduction to the various drug delivery systems and their opportunities from chemistry, materials, biology, and nanomedical standpoints. The chapters provide a comprehensive introduction to the field and the subfield, with a deeper discussion on the individual modalities for molecular imaging and their present status of clinical translation.…

Taschenbuch. Condición: Neu. Neuware - Bioceramics play an important role in repairing and regenerating defective or damaged bone. This volume reviews the latest advances in the field. Offering guidance for biomedical engineering researchers and material scientists, the book summarizes innovative concepts, bioceramic design, and methods for material synthesis and drug delivery. It covers design and fabrication of these materials, down to the nanoscale, and includes chapters on medical device engineering using these materials. The book is designed to enhance study and career development for those in this field and to facilitate further research and opportunities for new solutions.…

Taschenbuch. Condición: Neu. Neuware - The endothelium is an excellent example of where biology meets physics and engineering. It must convert mechanical forces into chemical signals to maintain homeostasis. It also controls the immune response, drug delivery through the vasculature, and cancer metastasis. Basic understanding of these processes is starting to emerge and the knowledge gained from research is now being used in applications from drug delivery to imaging modalities. This book reviews current knowledge in mechanobiology of the endothelium and its implications for the development of theranostic devices.…