Crc press nov 2009 (5 resultados)

Buch. Condición: Neu. Neuware - In the past, an organization's technical methodologies were expected to fulfill project management process needs. However, they sometimes fell short of applying what is known today as 'professional project management' concepts and practices. Written by one of the nation's most highly regarded project management mentors, The Complete Project Management Methodology and Toolkit delineates a 'business-relevant' methodology that can be introduced across different industries and business environments.The book describes the ProjectPRISM(TM) Project Management Methodology, an innovative, matrix-based approach to conducting project management that introduces relevant concepts, practices, and tools in an effective project management solution. Aligned with common business practices, Gerard Hill's method demonstrates how to develop project plans, keep on schedule, manage budgets, maintain areas of responsibility, and evaluate a project's progress from concept to completion. The text also offers insight for customizing the methodology to meet the unique needs of individual organizations.Project management has emerged as a professional discipline and is coming into the mainstream just when it appears to be most needed in the business environment. Demonstrating that project management, in many ways, is business management, the author provides an exceptional foundation for creating a fine-tuned project management practice and a relevant business solution for every organization.…

Buch. Condición: Neu. Neuware - The existence and functioning of intrinsically disordered proteins (IDPs) challenge the classical structure-function paradigm that equates function with a well-defined 3D structure. Uncovering the disordered complement of proteomes and understanding their functioning can extend the structure-function paradigm to herald new breakthroughs in drug development. Structure and Function of Intrinsically Disordered Proteins thoroughly covers the history up to the latest developments in this field.After examining the principles of protein structure, the classical paradigm, and the history of structural disorder, the book focuses on physical techniques for the identification and characterization of IDPs. It discusses proteomic and bioinformatic approaches and shows how IDPs behave under crowding conditions in living cells. The next several chapters describe the structure, correlating biological processes, and molecular mechanisms of IDPs. The author also explores the evolutionary advancement of structural disorder in proteomes and possible ways of extending the structure-function paradigm to encompass both ordered and disordered states of proteins. He concludes with discussions on the involvement of IDPs in various diseases and how to establish rational drug design through detailed characterization of IDPs.Although drug discovery rates have leveled off, new insight generated by the study of IDPs may offer fresh strategies for drug development. This work illustrates how these proteins defy the structure-function paradigm and play important regulatory and signaling roles.…

Buch. Condición: Neu. Neuware - Widely used in medical research, pharmaceutical and fine chemicals industries, biological and physical sciences, and security and environmental agencies, mass spectrometry techniques are continually under development. In Practical Aspects of Trapped Ion Mass Spectrometry: Volume V, Applications of Ion Trapping Devices, an international panel of authors presents a world-wide view of the practical aspects of recent progress using trapped ion devices.In contrast to previous texts, which have concentrated generally on a single or limited range of ion trapping techniques, a key feature of this compilation of contributions is its coverage of all the ion trapping techniques currently in use. Spanning sixteen chapters, the text examines: - Ion/neutral and ion/ion reactions - Structural characterization of proteins and peptides using quadrupole ion trap mass spectrometry, Fourier transform - ion cyclotron resonance (FT-ICR) mass spectrometry, and traveling wave ion mobility mass spectrometry - Ion spectroscopy and electron diffraction - Conformational analysis of protein isobaric charge states - Practical examples of trapped-ion technology that reflect the wide diversity of applications of trapped-ion devices This text is the first detailed account of the application of new and established mass spectrometric techniques utilizing trapped or confined ions for prolonged investigation and increased sensitivity. Each chapter contains complete references and utilizes a consistent format and writing style, with all terms, acronyms, procedures, and equations thoroughly explained. The strong editorial input to the diverse sections enables readers to readily appreciate the commonalities of topics ranging from theory of instrument operation to proteins, flavonoids, atomic clocks, and single ion mass spectrometry.…

Buch. Condición: Neu. Neuware - Enterprise-Scale Agile Software Development is the collective sum of knowledge accumulated during the full-scale transition of a 1400-person organization to agile development-considered the largest implementation of agile development and Scrum ever attempted anywhere in the world. Now James Schiel, a certified Scrum trainer and member of the Scrum Alliance, draws from his experience at the helm of that global four-year project to guide you and your organization through the transition. He lends his insight on how you can use Scrum as an organizational framework and implement XP practices to define how software is written and tested. He provides key information and tools to assess potential outcomes and then make the best corresponding choices in any given situation. Schiel sequences chapters to match typical developmental progression, and in addition to practical guidance, he provides a tool kit from which you can take ideas and select what works for you. Covering quality development practices based on ISO 9001, which help you create consistently high-quality software in a cost-efficient manner, this invaluable resource shows you how to- - Improve project management practices and product quality assurance - Adopt new management methods and requirements - Involve your current customers in development, while inviting new ones Much more than a mere 'body of knowledge,' this volume goes beyond standardizing agile and Scrum practices. It breaks up the process into manageable tasks, illustrating how to set the stage for the change, plan it, and then initiate it. Using the methods and information presented, any organization should be able to achieve a nearly seamless transition to agile.…

Buch. Condición: Neu. Neuware - Computing is ubiquitous and if you think otherwise, that in itself might be the best evidence that it is so. Computers are omnipresent in modern life and the multimedia computing environment of today is becoming more and more seamless.Bringing together contributions from dozens of leading experts, Ubiquitous Multimedia Computing educates readers on Ubi-Media Computing on three levels: infrastructures, where fundamental technologies are being developed; middleware, where the integration of technologies and software systems continues to be defined; and applications, where its concepts are evolving into real-world products and processes. In presenting a wealth of new directions and new technology that is changing the way we communicate, learn, play, and live day by day, this book - - Examines various architectures for delivering multimedia content including streaming devices , wireless networks, and various hybrids - Looks at rapidly developing sensor technology including wearable computers - Demonstrates the use of advanced HCI devices that allow the simplest body gestures to govern increasingly complex tasks - Introduces newsputers that take the use of embedded image information in a host of practical directions - Looks at how ubiquitous computing can eliminate traffic congestion and improve the efficiency and quality of medical care - Looks at how computing is personalizing learning environments and revolutionizing our approach to the three R's. While these pages serve as a timely reference for researchers working in all areas of product development and human computer interaction, they also provide engineers, doctors, and many other professionals, as well as educators and graduate students with a view that reveals the otherwise invisible seams of this age of ubi-media computing.…