birkhäuser birkhäuser feb 2012 (104 resultados)

Taschenbuch. Condición: Neu. Neuware -nen, zu erganzen und zu vertiefen.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 488 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -We present here the mathematical papers of Hassler Whitney. This collection contains all the published papers, with the exception of some short announcements that Whitney did not wish to be included. We also include the introduction to his book Geometric Integration Theory, and one previously unpublished manuscript on the four-color problem. The papers are presented under some broad categories: graphs and combinatorics, differentiable functions and singularities, analytic spaces, manifolds, bundles and characteristic classes, topology and algebraic topology, geometric integration theory. Whitney intended to write an introduction to this collection. Unfortunately he left us no manuscript at the time of his death, May 10, 1989. We had discussed the possibility of using his paper 'Moscow 1935 - Topology moving toward America,' written for the Centennial of the American Mathematical Society, as part of his introduction to this collection, an idea which he much liked. We therefore include this paper, which contains personal information as well as mathematical reflections, as Whitney's own introduction to these volumes. Whitney's mathematical style, like his personal style, was that of an explorer and pioneer. One of the pictures included in these volumes shows him as a mountain climber. In mathematics, he preferred to work on undeveloped areas: break new ground and build foundations. During the last twenty years of his life he concentrated his efforts on developing an educational system that builds on the natural tendency in children to be explorers.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 612 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -Life and work of a philosopher cannot be unravelled into separate strands. The true events of such a life are only thoughts. Kant has no other biography than the history of his thought. He lived most of his life in one city - Konigsberg, and never ventured beyond the fron tiers of East Prussia. He did not seek fame, he did not gain power; neither in living, nor in loving, did he encounter turbulence. He never married. Outwardly, Kant's life ran smoothly and uniformly. Perhaps it was more monotonous than the lives of other philosophers. That could not be said of the inner life, the life of the mind. There everything was wondrously alive. Daring ideas came into being, gathered strength, clashed with other ideas, yielded ground or ripened in the strife. Kant's thought roamed the continents, pushed beyond the confines of the earth, strove to the farthest reaches of the universe. His thought ix Immanuel Kant delved deeply into the human soul in order to know itself. It was in tense and dramatic. Almost all methods of modern philosophical enquiry are rooted in Kant. His ideas have undergone change, but they live on. A knowl edge of Kant's philosophy is a good introduction to the study of phi losophy in general. He teaches us to think independently.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 312 pp. Englisch.

Taschenbuch. Condición: Neu. Neuware -Bei gewissen Problemen der Instandhaltung von Maschinen, der Steuerung von Transport-, Umschlag- und Lagerhaltungsprozessen, aber auch bei Problemen der industriellen Rinderhaltung und der statistischen Qualitatskontrolle sind in zeitlicher Aufeinanderfolge Entscheidungen zu treffen, die selbst unter zufalIigen Einflussen in einem gewissen Sinne optimal sind. Das vorliegende Lehrbuch solI an Hand derartiger konkreter Entscheidungsprobleme den Leser auf induktivem Wege in die Methoden del' stochastischen dynamischen Optimierung einfUhren. Dabei wird besonderer Wert auf eine vom Einfachen zum Komplizierten fort schreitende, del' jeweiIigen Aufgabenstellung angepaBte ModelIierung gelegt. Fur die so gewonnenen MARKovschen Entscheidungsmodelle werden exemplarisch Losungs methoden entwickelt. Insbesondere werden Modelle untersucht, deren Struktur die Optimalitat von Strategien einfacher Bauart sichert. Derartige Strategien sind nicht nurleicht anwendbar, sondern lassen sich auch durch effektivere Verfahren rechen technisch ermitteln, als es Wertiteration und Entscheidungsiteration allgemein vermogen. Auf diese Weise wird das klassische dynamische Programmieren zugunsten einer strukturierten dynamischen Optimierung etwas zurUckgedrangt. Das Buch besteht aus drei Teilen. In den ersten beiden Kapiteln wird die BELLMAN sche dynamische Optimierung zur Losung endlichstufiger stochastischer Entschei dungsprobleme an Beispielen entwickelt.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 276 pp. Deutsch.

Taschenbuch. Condición: Neu. Neuware -Dieses Buch behandelt die allgemeine Theorie der Orthogonalpoly nome beztiglich einer nichtnegativen Belegung tiber der reellen Zahlen geraden. Ala Vorkenntnis wurde bei dem Leser - auBer den tiblichen Grundlagen der Analysis - das Absolvieren eines einftihrenden Kurses uber reelle Funktionen vorausgesetzt. Nur fur das Studium des letzten Kapitela sind einige Kenntnisse aus der Theorie der Funktionen einer komplexen Veranderlichen erforderlich;' lch hoffe, jedemLeser etwas Nutzliches zu bieten, ob er sich zwecks Anwendungen der fertigen Resul tate, um Material ftir eine Vorlesung oder ala zukiinftiger Forscher an mein Buch wendet. Auch dem Fachmann hoffe ioh manches Neue sagen zu konnen. Seit dem ersten Erscheinen der MonographIe von G. SZEGlS sind dreiBig Jahre verflossen. In diesen drei Jahrzehnten galt sein ausgezeichnetes Buch als Richtschnur fur die weitere Forschung. Die 195,9 erschienene zweite Auflage des Szegoschen Werkes brachte verhaltnismaBig wenig Erganzungen zum Original. Neuere Erscheinungen, wie die Bucher von F. TRICOMI und G. SANSONE sowie die ftir uns interessanten Teile des »Bateman Project« beschaftigen sich in erster Linie mit den speziellen Orthogonalpolynomen. Die Monographie von JA. L. GERONIMUS he handelt ausschlieBlich die Szegosche Theorie. Es fehIte eine zeitgemaBe nbersicht der allgemeinen Theorle der Orthogonalpolynome. lch hoffe, mit meinem Buch diese Lucke ausftillen zu konnen. Dnter »allgemeine Theorie« sei verstanden, daB aHe Resultate aus den heiden Tatsachen hergeleitet wurden, daB es sich um Polynome handelt, und daB die Folge dieser Polynome beztiglich einer vorgegebenen Belegung ein Ortho gonalsystem bildet.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 296 pp. Deutsch.

Taschenbuch. Condición: Neu. Neuware -In den meisten Darstellungen der Entwicklung der Mathema tik im 17. Jahrhundert wird man den Namen Faulhaber ver geblich suchen, obwohl Johannes Faulhaber immer wieder, wenn auch nur bei einigen Spezialisten wie den Mathematikern C. G. J. Jacobi und A. F. Mobius aufgrund seiner mathematischen Lei stungen Interesse zu erwecken vermochte. Dennoch gibt es in den Faulhaber-Biographien, die seit dem 18. Jahrhundert zu meist in Ulm und Umgebung, der Heimat Faulhabers, erschienen sind, bislang keine angemessene oder gar vollstandige Wurdigung seines mathematischen Werks. Eine solche Wurdigung erscheint aus verschiedenen Grunden wunschenswert. Die mathematischen Entdeckungen Faulhabers sind nicht nur gemessen an den Lei stungen deutscher Mathematiker des 16. Jahrhunderts heraus ragend, sondern auch im Vergleich zu anderen Errungenschaf ten der Mathematik des 17. Jahrhunderts, das Zeitgenossen als ein Jahrhundert der Mathematik galt, durchaus bemerkenswert. Am auffalligsten und wohl auch von Faulhaber selbst als seine groBte Entdeckung eingeschatzt sind die Summen und hoheren Summen der Potenzen naturlicher Zahlen bis zum Exponenten 17 in Form der heute sogenannten Faulhaberpolynome. Die Re konstruktion des Findungsweges dieser Potenzsummen auf der Grundlage der Faulhaber zuganglichen elementaren Methoden hat Mathematiker bis in die jungste Zeit beschaftigt.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 288 pp. Deutsch.

Taschenbuch. Condición: Neu. Neuware -Dieses Lehrbuch bietet eine umfassende Darstellung derjenigen Verfahren zur Lösung nichtlinearer Optimierungsprobleme, die nach dem gegen- wärtigen Wissensstand als zuverlässig und effizient gelten. Es führt den Leser von den theoretischen Grundlagen bis auf den Stand der gegen- wärtigen Forschung. Dabei werden nur mathematische Vorkenntnisse vorausgesetzt, wie sie das Grundstudium sowohl für Mathematiker als auch für mathematisch orientierte Anwender üblicherweise bereitstellt. Neben einer sorgfältigen Erarbeitung der Konvergenzeigenschaften der Verfahren werden auch wichtige Details der Implementierung diskutiert. Das Buch enthält zahlreiche durchgerechnete Beispiele und Illustrationen, die dem Leser eine bessere Vorstellung über die Vorgehensweise und Leistungsfähigkeit der Verfahren vermitteln können. Zahlreiche Übungs- aufgaben verschiedenen Schwierigkeitsgrades ermöglichen dem Leser die Kontrolle seines Verständnisses. Das vorgelegte Werk geht sowohl in der Breite des behandelten Stoffes als auch in der Tiefe der mathematischen Analyse über die bestehenden Lehrbücher hinaus. Für die meisten Verfahren werden detailliert ausgearbeitete Konvergenzbeweise angegeben. Eine Fülle von Resultaten aus den letzten 10 Jahren erscheint hier zum ersten Mal in Buchform. Neben in Handrechnung nachvollziehbare einfache Beispiele treten ausgearbeitete Anwendungsbeispiele aus der Praxis.Springer Basel AG in Springer Science + Business Media, Heidelberger Platz 3, 14197 Berlin 572 pp. Deutsch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Volume 43 of 'Progress in Drug Research' contains five reviews and the various indexes which facilitate its use and establish the connection with the previous volumes. The articles in this volume deal with high cholesterol blood levels and other dyslipidemias; search of ideal antihypertensive drugs; the natural PQlyamines and the immune system; biologically active quinazolones and with production and action of interferons. In the 35 years the PDR has existed, the Editor has enjoyed the valuable help and advice of many colleagues. Readers, the authors of the reviews, and last but not least, the reviewers have all contributed greatly to the success of this series. Although the comments received so far have generally been favorable, it is nevertheless necessary to analyze and to reassess the current position and the future direction of such a review series. So far, it has been the Editors intention to help disseminate information on the vast domain of drug research, and to provide the reader with a tool with which to keep abreast of the latest developments and trends. The reviews in PDR are useful to the non-specialist, who can obtain an overview of a particular field of drug research in a relatively short time. The specialist readers of PDR will appreciate the reviews' comprehensive bibliographies, and, in addition, they may even get fresh impulses for their own research. Finally, the readers can use the 43 volumes of PDR as an encyclopedic source of information. 330 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -We have again brought together for the Third International Symposium on Charge and Field Effects in Biosystems (July 21-27, 1991), a group of scientists whose interests reside in the fields of bioelectrochemistry, bioenergetics, and bioelectric phenomena. Like the previous symposia at the University of Nottingham (1983) and Virginia Commonwealth University (1989) the topics discussed were related to bioelectric phenomena, including solid state theoretical and experimental approaches to charge and energy transfer in biomolecular and cellular systems, ion and electron transport properties of biological and artifical membranes, the effects of electric fields on biological systems, photoinduced bioelectrochemical phenomena, and the applications of bioelectrochemical technology. The present conference also introduced procedures which may well serve to define the mechanisms of various bioelectrical phenomena, including electroporation for gene transfer and electro fusion for hybridoma formation. Favorable comments made during and after the Symposium indicated that a further conference should be held. Tentatively, plans are being considered for 1993 or 1994. Milton 1. Allen Stephen F. Cleary Arthur E. Sowers Donald D. Shillady Acknowledgments The Editors wish to express their thanks to Rinnie O'Connor, Diane Ruff, Rae Gerber, and lody Allen for their assistance in preparing the Symposium volume for publication. Our special thanks also to the reviewers who performed their tasks with enthusiastic promptness. 516 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -From Sunday evening, April 5, until Thursday afternoon, April 9, 1992,49 scientists from 10 countries met at the Centro Stefano Franscini on Monte VeritA overlooking Ascona, in the state of Ticino in Switzerland, for an international workshop on Muonic Atoms and Molecules. More than two-thirds of the participants presented their results in talks of 20 to 40 minutes' duration. In addition, Prof. Gabriele Torelli gave, under the patronage of the Ministro del Ambiente of the state of Ticino, Dr. Mario Camani, a lecture in Italian entitled 'Un modo insolito di studiare Ie proprieta nucleari, atomiche e chimiche'. The scientific program commenced on Monday morning with discussions centering on nuclear muon capture and nuclear fusion and fission, moving on to muonic atom spectroscopy in the afternoon. All of Tuesday was devoted to muon catalyzed fusion and muon transfer. On Wednesday morning, different aspects of hot muonic atoms were discussed, followed by informal gatherings in the afternoon and evening. On Thursday morning we took a look at the prospects for the TRIUMF and PSI meson factories, and new experimental methods. The conference was brought to a close in the afternoon with C. P. summarizing the events of the past days. The two organizers want to thank all participants for their contributions and for the lively discussions which often followed the different talks. 388 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The conference on BIFURCATIONS: ANALYSIS, ALGORITHMS, APPLICATIONS took place in Dortmund in August 18 - 22, 1986. More then 150 Scientists from 16 countries participated in the meeting, among them mathematicians, engi neers, and physicists. A broad spectrum of new results on bifurcation was covered by 49 talks. The diversity of the range of treated topics and of involved fields inspired fruitful discussions. 36 refereed papers are contained in these proceedings. The subjects covered treat bifurcation problems, ranging from theoretical investigations to numerical results, with emphasis placed upon applications. The more theoreti cal papers include the topics symmetry breaking, delay differential equations, Cornu spirals, homoclinic orbits, and selfsimilarity. Different kinds of bifurcations are treated: Hopf bifurcation, bifurcation from continuous spec trum, complex bifurcation, and bifurcation near tori. Several numerical as pects are discussed, among them continuation, block elimination, and spectral methods. Algorithms are proposed for approximating manifolds, calculating pe riodic solutions and handling multi-parameter problems. Ample space is devoted to applications. Classical phenomena from fluid mechanics (such as convection rolls and th~ Taylor vortex problem), buckling, and reaction-diffusion pro blems are considered. Other applications of bifurcations include railway vehicle dynamics, computer graphics, semiconductors, drilling processes, simu lation of oil reservoirs, and rotor dynamics. The proceedings reflect current research in bifurcation. They are an attempt to bring together researchers from differ~nt disciplines to stimulate common effort towards a better understanding and handling of bifurcation pro blems. 368 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The Operator Theory conferences, organized by the Department of Mathematics of INCREST and the Department of Mathematics of the University of Timi~oara, are conceived as a means to promote cooperation and exchange of information between specialists in all areas of operator theory. This book comprises carefully selected papers on theory of linear operators and related fields. Original results of new research in fast developing areas are included. Several contributed papers focus on the action of linear operators in various function spaces. Recent advances in spectral theory and related topics, operators in indefinite metric spaces, dual algebras and the invariant subspace problem, operator algebras and group representations as well as applications to mathematical physics are presented. The research contacts of the Department of :viathematics of INCREST with the National Committee for Science and Technology of Romania provided means for developing the research activity in mathematics; they represent the generous framework of these meetings too. It is our pleasure to acknowledge the financial support of UNESCO which also contributed to the success of this meeting. We are indebted to Professor Israel Gohberg for including these Proceedings in the OT Series and for valuable advice in the editing process. Birkhauser Verlag was very cooperative in publishing this volume. Camelia Minculescu, Iren Nemethi and Rodica Stoenescu dealt with the difficult task of typing the whole manuscript using a Rank Xerox 860 word processor; we thank them for this exellent job. 356 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -If it is true that science proceeds from a romantic through a scientific to a technological stage, then research on bird orientation is certainly on its move from its first to its second grade, and recent developments in radiotelemetry and satellite tracking of migrating birds might already indicate the advent of the third stage. At this juncture, Orientation in Birds is a timely account. Even though the study of animal migration in general, and bird navigation in particular, has produced a literature of impressive proportions, the threads provided by the plethora of research papers, review articles and symposiums volumes have not yet been knitted into a theoretical fabric. This is partly due to our still incomplete understanding of fundamen tal topics in avian navigation. The answer to the most intriguing question of how a bird displaced to 'unknown' territory finds its way back home is as obscure now as it was a few decades ago. Whether and how birds solve this problem by using far ranging grid-maps or more local familiar-area maps, as has been proposed off and on, is still a matter of heated debates. These debates frequently center around provocative hypotheses - let alone the question about the physical (topographic, magnetic, infrasonic, olfactory) parameters which might constitute such maps. 344 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It is generally accepted that all living organisms present on earth derive from one single primordial cell born several billion years ago. One important step in the evolution occurred some 1. 5 billion years ago with the transition from small procaryote cells with relatively simple internal structures such as bacteria to larger and more compleX: eucaryotic cells such as those found in higher animals and plants. Large membrane proteins which enable the cells to communicate appeared early in evolution, and it is believed that the nerve membrane receptors and ionic channels which are observed today in both invertebrate and vertebrate species derive from a common ancestor. Basically, the three identified superfamilies, 1) ionotropic receptors (i. e. receptors containing an integral ionic channel), 2) metabotropic receptors (receptors coupled to G proteins) and 3) voltage-dependent ionic channels (Na+, K + and Ca2+ channels) were already well differentiated when vertebrates separated from invertebrate species. The large number of subtypes which are observed in each superfamily may be of more recent evolutionary origin. To understand how this happened, the best approach was to compare the sequences and the properties of the receptors and ionic channels in species sufficiently distant in the evolutionary tree. In the present volume, many of the best specialists in the field of comparative molecular neurobiology, several of them working on vertebrate and invertebrate species, have accepted to report their most recent findings. 448 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In evolutionary time scales natural disturbances have affected the vegetation on Earth. During the Quaternary the forest biomes of the tropics were subjected to manifold disturbances. Climate changes and climate oscillations were associated with changing precipitation and drought regimes, flooding, siltation, landslides, etc. The prehistorical forest was also influenced by the effects of large wildlife populations. Large-scale catastrophies in the forest biomes were mainly caused by abiotic environmental alterations, the small-scale disturbances were and still are related to both biotic and abiotic processes. Both the large-and the small-scale disturbances have played a significant role in shaping distribution, dynamics, structure and composition of the paleoforest. After the expansion of hominids and early humans, and later, by modern humans, the anthropogenic influences on the tropical forest began to overlap natural disturbances. Today's anthropogenic impacts on the tropical forests differ qualitatively and quanitatively from the natural disturbances. The speed of tropical deforestation and savannization is dramatically increasing. The physical and chemical impacts of forest conversion and biomass burning add to other anthropogenic influences on the atmosphere and climate. The expected anthropogenic climate change will also have considerable impacts on the tropical flora and fauna. The book on 'Tropical Forests in Transition' synthesizes information on changing environmental conditions and human impacts on the tropical forest by looking back to the paleoecology, analyzing the impact of modern human populations and modeling the future of the tropical forest in a changing environment. The aim of the book is to strengthen multidisciplinary thinking in disturbance ecology. 284 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This monograph aims to provide a powerful general-purpose proof tech nique for the verification of systems, whether finite or infinite. It extends the idea of finite local model-checking, which was introduced by Stirling and Walker: rather than traversing the entire state space of a model, as is done for model-checking in the sense of Emerson, Clarke et ai. (checking whether a (finite) model satisfies a formula), local model-checking asks whether a particular state satisfies a formula, and only explores the nearby states far enough to answer that question. The technique used was a tableau method, constructing a tableau according to the formula and the local structure of the model. This tableau technique is here generalized to the infinite case by considering sets of states, rather than single states; because the logic used, the propositional modal mu-calculus, separates simple modal and boolean connectives from powerful fix-point operators (which make the logic more expressive than many other temporal logics), it is possible to give a rela tively straightforward set of rules for constructing a tableau. Much of the subtlety is removed from the tableau itself, and put into a relation on the state space defined by the tableau-the success of the tableau then depends on the well-foundedness of this relation. The generalized tableau technique is exhibited on Petri nets, and various standard notions from net theory are shown to playa part in the use of the technique on nets-in particular, the invariant calculus has a major role. 124 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Beginning in 1983, the Swedish Council for Planning and Coordination of Research has organized an annual workshop devoted to some aspect of the behavior and modeling of complex systems. These workshops have been held at the Abisko Research Station of the Swedish Academy of Sciences, a remote location far above the Arctic Circle in northern Sweden. During the period of the midnight sun, from May 4-8, 1987 this exotic venue served as the gathering place for a small group of scientists, scholars, and other connoisseurs of the unknown to ponder the problem of how to model 'living systems,' a term singling out those systems whose principal components are living agents. The 1987 Abisko Workshop focused primarily upon the general system-theoretic concepts of process, function, and form. In particular, a main theme of the Workshop was to examine how these concepts are actually realized in biological, economic, and linguistic situations. As the Workshop unfolded, it became increasingly evident that the central concern of the participants was directed to the matter of how those quintessential aspects of living systems-metabolism, self-repair, and replication-might be brought into contact with the long-established modeling paradigms employed in physics, chemistry, and engineering. 296 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Robust Control is one of the fastest growing and promising areas of research today. In many practical systems there exist uncertainties which have to be considered in the analysis and design of control systems. In the last decade methods were developed for dealing with dynamic systems with unstructured uncertainties such as HOO_ and Pds. I-optimal control. For systems with parameter uncertainties, the seminal paper of V. L. Kharitonov has triggered a large amount of very promising research. An international workshop dealing with all aspects of robust control was successfully organized by S. P. Bhattacharyya and L. H. Keel in San Antonio, Texas, USA in March 1991. We organized the second international workshop in this area in Ascona, Switzer land in April 1992. However, this second workshop was restricted to robust control of dynamic systems with parameter uncertainties with the objective to concentrate on some aspects of robust control. This book contains a collection of papers presented at the International Workshop on Robust Control held at the Centro Stefano Franscini, Monte Verita, Ascona, Switzer land on April 12-17, 1992 as well as a list of open problems presented during a dis cussion session at the workshop. Thirtyfive leading researchers from all over the world working in the area of robust control of dynamic systems with parameter uncertainties were invited to present their recent results and to discuss with their colleagues the recent advances in this field. 332 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the week of October 23-27,1989, Northwestern University hosted an international conference on the theme 'Diffusion Processes and Related Problems in Analysis.' This was attended by 105 partici pants representing 14 different countries. The conference, which is part of the 'Emphasis Year' program traditionally supported by the Mathematics Department, was additionally supported by grants from the National Science Foundation, the National Security Agency, the Institute for Mathematics and Applications, as well as by supplemen tary sources from Northwestern University. The purpose of this meeting was to bring together workers in vari ous parts of probability theory, mathematical physics, and partial dif ferential equations. Previous efforts in this direction were represented by the 1987 AMS Summer Research Conference 'Geometry of Random Motion' co-sponsored with Rick Durrett, the proceedings of which ap peared as volume 73 in the AMS series 'Contemporary Mathematics.' The present effort is intended to extend beyond the strictly geometric theme and to include problems of large deviations, stochastic flows, and other areas of stochastic analysis in which diffusion processes play a leading role. 536 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Welcome to the world of computer programming. Your Texas Instruments TI-99/4A is a real 16-bit microcomputer, complete with sound and color graphics. Making these features do what you want may seem impossible at fIrst, but don't worry; there's nothing mysterious about computer programming. Learning to program computers simply means learning a new language-in this case, TI BASIC (for Beginner's All purpose Symbolic Instruction Code), a version of the most popular language used on today's microcomputers. This book will teach you, step by step, how to tell your machine what you wish it to do-in other words, how to program it. But that's not all. You'll also find chapters on general microcomputer principles, cassette deck use, the TI-99/4A as a terminal for much larger systems, options for expansion, and a list of resources for getting the most out of your home computer. With the 99/4A you have access to a large library of programs, or software, already written by someone else. Without knowing anything about programming, you can use this software to play games, learn math, or store addresses. But at some point you'll want to make your personal computer really personal. You might want to create your own video game or compose a tune. And that's when you'll want to learn programming. 200 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Die Arzneimittelforschung hat sich in den letzten zwanzig J ahren stiirmisch ent wickelt und bewegt sich nicht mehr nur auf den naheliegenden Disziplinen der Chemie, Pharmakologie, Toxikologie und Medizin, sondern greift auch auf die der Physiologie, Biochemie, physikalischen Chemie und Physik iiber. Dem einzelnen ist es deshalb kaum noch moglich, die Originalliteratur zu verfolgen, soweit sie auBerhalb seiner eigenen Forschungsrichtung liegt, und auch da besteht die groBe Gefahr der aIlzu engen Spezialisierung. Die Erkenntnis dieser Entwicklung und ihrer Folgeerscheinungen hat den Herausgeber vor einigen J ahren dazu bewogen, diese Monographienreihe ins Leben zu rufen, und er empfindet groBe Genugtuung, hiermit bereits den sechsten Band seinen Lesern iibergeben zu konnen. Er ergreift freudig die Gelegenheit, nicht nur den Autoren flir ihre Bereitwilligkeit, mit welcher sie einzelne Forschungsgebiete in Ubersichtsreferaten dargestellt haben, sondern auch befreundeten Forschern und Fachkollegen fiir ihre vielen wertvollen Anre gungen, Kritiken und Vorschlage zu danken, ist es ihm doch nur dank dieser Unter stiitzung von seiten der Fachwelt ermoglicht worden, diese Zusammenarbeit auf internationaler Ebene zu organisieren und die Fortschritte der Arzneimittel/orschung zu einem niitzlichen Werk auszugestalten. Er hofft, daB ihm diese wertvolle Unter stiitzung, ohne die die Fortsetzung eines derartigen Werkes unmoglich ware, auch weiterhin in vollem Umfang erhalten bleibt. In den bis jetzt vorliegenden sechs Banden wurden ganz verschiedene Gebiete der Arzneimittelforschung dargesteIlt, und die Arbeiten flir die Berichterstattung werden nach verschiedenen aktuellen Richtungen hin weiter vorgetrieben. 424 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -During the first half century of genetics, coinciding with the first half of this cen tury, geneticists dreamt of the repair of genetic disease by altering or replacing defective genes. H. J. Muller wrote of the great advantages of mutations, 'nanoneedles' in his apt term, for delicately probing physiological and chemical processes. In the same spirit, genes could be used to provide treatments of needle point delicacy. Yet, during this period no realistic possibility appeared; it remained but a dream. The situation changed abruptly at the half century. Microbial genetics and its offshoot, cell culture genetics, provided the route. Pneumococcus transformation showed that exogenous DNA could become a permanent part of the genome; yet attempts to reproduce this in animals produced a few tantalizing hints of success, but mostly failures. Transduction, using a virus as mediator, offered a better op portunity. The fITSt reproducible in vivo gene therapy in a whole animal came in 1981. This was in Drosophila, with a transposable element as carrier. Flies were 'cured' of a mutant eye color by incorporation of the normal allele, and the effect was transmissible, foreshadowing not only somatic, but germ line gene therapy. At the same time, retroviruses carrying human genes were found to be ex tremely efficient in transferring their contents to the chromosomes of cultured cells. 440 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Nullius in verba. . . Truth will be tested not by words. Horace (Epistles) Few read introductions except for book reviewers, who want to take a shortcut and avoid reading the book itself. However, tradition requires that the preface make public why the book was written at all (this is not supposed to include powerful reasons such as augmenting the ego of the editor and authors). Frequently, the inflationary tendency to publish in verbose length is in conflict with market forces and interest. No doubt, multidrug resistance is a 'fashionable' topic, but there are many fashions displayed on the cat-walk of scientific literature. One can rationalize that the forces driving our concern with multi drug resistance reflect the frustration of pharmaceutical companies and oncologists alike: as soon as a new anticancer drug enters clinical trials, cancer cells start eluding extinction with their elaborate and successful mechanisms. Many grants have been awarded and spent, only to confirm the futility of our efforts to defeat this cellular Darwinism. Our medical and scientific training makes it hard, if not impossible, to accept that the survival of a malignant cell, alone or as part of a tissue, is part of the continuance of life. Since exposure to noxious and lethal substances is unavoidable, cells have been forced to develop a multitude of mechanisms to prevent entry or accelerate exit of such materials from intracellular space. 296 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -1: Statics.- 1.1 Mean Field Models.- Hopfield Models as Generalized Random Mean Field Models.- The Martingale Method for Mean-Field Disordered Systems at High Temperature.- On the Central Limit Theorem for the Overlap in the Hopfield Model.- Limiting Behavior of Random Gibbs Measures: Metastates in Some Disordered Mean Field Models.- On the Storage Capacity of the Hopfield Model.- 1.2 Lattice Models.- Typical Profiles of the Kac-Hopfield Model.- Thermodynamic Chaos and the Structure of Short-Range Spin Glasses.- Random Spin Systems with Long-Range Interactions.- 2: Dynamics.- Langevin Dynamics for Sherrington-Kirkpatrick Spin Glasses.- Sherrington-Kirkpatrick Spin-Glass Dynamics Part II: The Discrete Setting. 396 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Perspectives on Anti-Inflammatory Drugs Inflammation is a very complicated process of interrelated events and cas cades that does not allow for an easily defined, focused attack for drug discovery. It is evident from years of research and development that certain classes of compounds (e.g., NSAIDs, steroids, and so on) have had a meas ure of success in alleviating pain and even dampening cellularlhormonal mechanisms involved in the process. Clear, mechanism-related therapies (e.g., for arthritis) and targeted drugs (e.g., for transplantation) have not been available in the past and, in reality, research in inflammation has re lied on more phenomenological approaches for resolving symptoms or on blatant cytoreductive approaches in cases like organ transplantation. In the last decade, approaches that have revealed novel cellular pathways in which intervention is possible for lymphocyte regulation (for example, cyclosporine and FK506) and small molecular weight mediators (e.g., leu kotriene inhibitors) are now either standard therapy or will be in a short time. These latter approaches have been the result of research from the 1970s up to the present. 320 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -\* Introduces a state-of-the-art method for the study of the asymptotic behavior of solutions to evolution partial differential equations.\* Written by established mathematicians at the forefront of their field, this blend of delicate analysis and broad application is ideal for a course or seminar in asymptotic analysis and nonlinear PDEs.\* Well-organized text with detailed index and bibliography, suitable as a course text or reference volume. 400 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Ever since the introduction of the polymerase chain reaction (peR) in 1986, morphologists, whose interests lie in the analysis of intact tissue structures, have been attempting to adapt this technique to intact cells or tissue sections to detect low copy numbers of DNA or RNA in situ while preserving tissue morphology. The significance of this objective is obvious. A technique finally materialized in 1990 when Dr. Ashley T. Haase and coworkers published results that used multiple prim ers with complementary tails in intact cells. Since then, a number of laboratories have successfully developed their own versions of the technique. In situ peR is now a well-recognized method that permits the detection of minute quantities of DNA or RNA in intact cells or tissue sections. As a result, morphological analysis of those target nucleotide sequences becomes possible. As anticipated, this ad vancement has led to significant improvement in our understanding of many nor mal and abnormal conditions, and its impact is becoming more evident as time passes. In situ peR has the characteristics of a new landmark in morphologic technol ogy-it is scientifically fascinating and technically challenging. In essence, it is a combination of in situ hybridization and conventional peR. The wealth of litera ture, experience and protocols for the two latter techniques can be applied to in situ peR. In situ peR also has its own unique aspects that were not addressed by the other two techniques. 152 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book contains both a synthesis and mathematical analysis of a wide set of algorithms and theories whose aim is the automatic segmen tation of digital images as well as the understanding of visual perception. A common formalism for these theories and algorithms is obtained in a variational form. Thank to this formalization, mathematical questions about the soundness of algorithms can be raised and answered. Perception theory has to deal with the complex interaction between regions and 'edges' (or boundaries) in an image: in the variational seg mentation energies, 'edge' terms compete with 'region' terms in a way which is supposed to impose regularity on both regions and boundaries. This fact was an experimental guess in perception phenomenology and computer vision until it was proposed as a mathematical conjecture by Mumford and Shah. The third part of the book presents a unified presentation of the evi dences in favour of the conjecture. It is proved that the competition of one-dimensional and two-dimensional energy terms in a variational for mulation cannot create fractal-like behaviour for the edges. The proof of regularity for the edges of a segmentation constantly involves con cepts from geometric measure theory, which proves to be central in im age processing theory. The second part of the book provides a fast and self-contained presentation of the classical theory of rectifiable sets (the 'edges') and unrectifiable sets ('fractals'). 268 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -With the help of recent technological advances in the study of cen tral nervous system function, important strides have been made in our knowledge regarding the pathophysiology of high blood pres sure. The understanding of neural mechanisms involved in the reg ulation of the cardiovascular system is of critical importance to the development of rational approaches to both the treatment and pre vention of this disease. It was in this spirit that a satellite symposium of the 13th Scientific Meeting of the International Society of Hyper tension was held in June 1990, in Bethesda, Maryland. The chapters, in this first of two volumes on the same general theme, are based on lectures presented at the symposium and it is hoped that these sum maries of recent research findings from prominent laboratories around the world will provide a stimulus for future research. The symposium would not have been possible without generous support from the National Institute on Alcohol Abuse and Alcoholism, Merck Frosst Canada, G. D. Searle Co. , Squibb Institute of Medical Research, Smith, Kline & Beecham Co. , Pfizer Co. , E. I. Dupont de Nemours Co. , Merck, Sharp & Dohme Co. , The UpJohn Co. , and Wyeth-Ayerst Co. While this volume was being prepared for publication, one of its contributors, Dr. Michael J. Brody, died suddenly. It is with deep sorrow and sympathy that we mourn the loss of our colleague. Dr. 300 pp. Englisch.

Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The simplest model of nuclear matter is a collection of point nucleons interacting through a two-body potential that accounts for scattering data and the properties of the deuteron. In order to use and to test this model we must be able, for a given two-body potential, to 'calculate the l 9 corresponding saturation curve of nucle~r matter. The Brueckner-Bethe metho- is one method of making this calculation. The available evidence suggests that, at present, the Brueckner-Bethe method can be used to locate the saturation point with an uncertainty of -1 2-3 MeV in energy and about 0.1 fm in~. This is not very high accuracy, but it is good enough to make a start on physically interesting calculations. In this paper I describe the Brueckner-Bethe method and illustrate it with numerical results. Some of the results are designed to test the accuracy of the method, some are comparisons with variational calculations, and a saturation curve for the full Reid potential is given. 400 pp. Englisch.