Birkhäuser basel okt 2012 (288 resultados)

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -'Fractals in Biology and Medicine' explores the potential of fractal geometry for describing and understanding biological organisms, their development and growth as well as their structural design and functional properties. It extends these notions to assess changes associated with disease in the hope to contribute to the understanding of pathogenetic processes in medicine. The book is the first comprehensive presentation of the importance of the new concept of fractal geometry for biological and medical sciences. It collates in a logical sequence extended papers based on invited lectures and free communications presented at a symposium in Ascona, Switzerland, attended by leading scientists in this field, among them the originator of fractal geometry, Benoit Mandelbrot. 'Fractals in Biology and Medicine' begins by asking how the theoretical construct of fractal geometry can be applied to biomedical sciences and then addresses the role of fractals in the design and morphogenesis of biological organisms as well as in molecular and cell biology. The consideration of fractal structure in understanding metabolic functions and pathological changes is a particularly promising avenue for future research. 397 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -One of the key concerns in modern control theory is the design of steering strategies. The implementation of such strategies is done by a regulator. Presented here is a self-contained introduction to the mathematical background of this type of regulator design. The topics selected address the matter of greatest interest to the control community, at present, namely, when the design objective is the reduction of the influence of exogeneous disturbances upon the output of the system. In a first scenario the disturbance signal is regarded as a deterministic time series with known dynamics but unknown parameters. The design objective is then the asymptotic disturbance compensation. In a second scenario, no information about the disturbance signal is available apart from some bounds. Here, in an H-approach, control strategies are worked out which will prove efficient for all such disturbances. The intention of this book is to present ideas and methods on such a level that the beginning graduate student will be able to follow current research. New results are included, especially for nonlinear control systems, and as a service to the reader, an extensive appendix presents topics from linear algebra, invariant manifolds and calculus of variations, information which is hardly to be found in standard textbooks. Contents: Introduction - The problem of output regulation - Introduction - Problem statement - Output regulation via full information - Output regulation via full error feedback - A particular case - Well-posedness and robustness - The construction of a robust regulator - Disturbance attenuation via H-methods - Introduction - Problem statement - A characterization of the L2-gain of a linear system - Disturbance attenuation via full information - Disturbance attenuation via measured feedback - Full information regulators - Problem statement - Time-dependent control strategies - Examples - Time-independent control strategies- The local case - Nonlinear observers - Problem statement - Time-dependent observers - Error feedback regulators - Examples - Nonlinear H-techniques - Introduction - Construction of the saddle-point - The local scenario - Disturbance attenuation via linearization - Matrix equations - Linear matrix equations - Algebraic Riccati equations - Invariant manifolds - Existence theorem - Outflowing manifolds - Asymptotic phase - Convergence for T - A special case - Dichotomies and Lyapunov functions - Hamilton-Jacobi-Bellman-Isaacs equation - Introduction - Method of characteristics - The equation of Isaacs - The Hamiltonian version of Isaacs' equation - Bibliography 168 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The controversy between the wave theory and the emission theory of light early in the nineteenth century has been a subject of numerous studies. Yet many is sues remain unclear, in particular, the reasons for rejecting Young's theory of light. It appears that further progress in the field requires a better grasp of the overall situation in optics and related subjects at the time and a more thorough study of every factor suggested to be of importance for the dispute. This book is intended to be a step in this direction. It examines the impact of the concept of interference of light on the development of the early nineteenth century optics in general, and the theory of light, in particular. This is not a his tory of the wave theory of light, nor is it a history of the debate on the nature of light in general: it covers only that part of the controversy which involved the concept of interference. Although the book deals with a number of scientists, scientific institutions, and journals, its main character is a scientific concept, the principle of interference. While discussing the reasons for accepting or rejecting this concept I have primarily focused on scientific factors, although in some cases the human factor is examined as well. The book is a revised Ph. D. dissertation (University of Minnesota, 1984) writ ten under Alan E. Shapiro. 271 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Generalized Schur functions are scalar- or operator-valued holomorphic functions such that certain associated kernels have a finite number of negative squares. This book develops the realization theory of such functions as characteristic functions of coisometric, isometric, and unitary colligations whose state spaces are reproducing kernel Pontryagin spaces. This provides a modern system theory setting for the relationship between invariant subspaces and factorization, operator models, Krein-Langer factorizations, and other topics. The book is intended for students and researchers in mathematics and engineering. An introductory chapter supplies background material, including reproducing kernel Pontryagin spaces, complementary spaces in the sense of de Branges, and a key result on defining operators as closures of linear relations. The presentation is self-contained and streamlined so that the indefinite case is handled completely parallel to the definite case. 252 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume is based on lectures notes for the courses delivered at the Cimpa Summer School: From Classical to Modern Probability, held at Temuco, Chile, be th th tween January 8 and 26 , 2001. This meeting brought together probabilists and graduate students interested in fields like particle systems, percolation, Brownian motion, random structures, potential theory and stochastic processes. We would like to express our gratitude to all the participants of the school as well as the people who contributed to its organization. In particular, to Servet Martinez, and Pablo Ferrari for their scientific advice, and Cesar Burgueiio for all his support and friendship. We want to thank all the professors for their stimulating courses and lectures. Special thanks to those who took the extra work in preparing each chapter of this book. We are also indebted to our sponsors and supporting institutions, whose interest and help was essential to organize this meeting: CIMPA, CNRS, CONI CYT, ECOS, FONDAP Program in Applied Mathematics, French Cooperation, Fundacion Andes, Presidential Fellowship, Universidad de Chile and Universidad de La Frontera. We are grateful to Miss Gladys Cavallone for her excellent work during the preparation of the meeting as well as for the considerable task of unifying the typography of the different chapters of this book. 240 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Many physical problems are meaningfully formulated in a cylindrical domain. When the size of the cylinder goes to infinity, the solutions, under certain symmetry conditions, are expected to be identical in every cross-section of the domain. The proof of this, however, is sometimes difficult and almost never given in the literature. The present book partially fills this gap by providing proofs of the asymptotic behaviour of solutions to various important cases of linear and nonlinear problems in the theory of elliptic and parabolic partial differential equations.The book is a valuable resource for graduates and researchers in applied mathematics and for engineers. Many results presented here are original and have not been published elsewhere. They will motivate and enable the reader to apply the theory to other problems in partial differential equations. 192 pp. Englisch.…

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Editorial: Springer, Basel, Birkhäuser Basel, Birkhäuser Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -It follows naturally from the widely accepted Darwinian dictum that failures of populations or of species to adapt and to evolve under changing environments will result in their extinction. Population geneti cists have proclaimed a centerstage role in developing conservation biology theory and applications. However, we must critically reexamine what we know and how we can make rational contributions. We ask: Is genetic variation really important for the persistence of species Has any species become extinct because it ran out of genetic variation or because of inbreeding depression Are demographic and environmental stochas ticity by far more important for the fate of a population or species than genetic stochasticity (genetic drift and inbreeding) Is there more to genetics than being a tool for assessing reproductive units and migration rates Does conventional wisdom on inbreeding and 'magic numbers' or rules of thumb on critical effective population sizes (MVP estimators) reflect any useful guidelines in conservation biology What messages or guidelines from genetics can we reliably provide to those that work with conservation in practice Is empirical work on numerous threatened habitats and taxa gathering population genetic information that we can use to test these guidelines These and other questions were raised in the invitation to a symposium on conservation genetics held in May 1993 in pleasant surroundings at an old manor house in southern Jutland, Denmark. 443 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In several proofs from the theory of finite-dimensional Lie algebras, an essential contribution comes from the Jordan canonical structure of linear maps acting on finite-dimensional vector spaces. On the other hand, there exist classical results concerning Lie algebras which advise us to use infinite-dimensional vector spaces as well. For example, the classical Lie Theorem asserts that all finite-dimensional irreducible representations of solvable Lie algebras are one-dimensional. Hence, from this point of view, the solvable Lie algebras cannot be distinguished from one another, that is, they cannot be classified. Even this example alone urges the infinite-dimensional vector spaces to appear on the stage. But the structure of linear maps on such a space is too little understood; for these linear maps one cannot speak about something like the Jordan canonical structure of matrices. Fortunately there exists a large class of linear maps on vector spaces of arbi trary dimension, having some common features with the matrices. We mean the bounded linear operators on a complex Banach space. Certain types of bounded operators (such as the Dunford spectral, Foiadecomposable, scalar generalized or Colojoara spectral generalized operators) actually even enjoy a kind of Jordan decomposition theorem. One of the aims of the present book is to expound the most important results obtained until now by using bounded operators in the study of Lie algebras. 232 pp. Englisch.…

Idioma: Inglés
Editorial: Birkhäuser Basel Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In November 1998 many of the key leaders of new drug discovery forinflammatory diseases gathered at Hershey, Pennsylvania for the 9thInternational Conference of the Inflammation Research Association. TheConference was held over a five day period and provided a stimulatingenvironment for the open exchange of important advances in basicinflammation research as well as new drug discovery and development.This book encompasses some of the highlights of several presentationsmade at the Conference. It contains some of the latest and importantdevelopments in the field of inflammation research.Topics include the status of eotaxin and chemokines in asthma andallergy, signal transduction and regulation of diverse mediators such asthe JNK group of MAP kinases, TNF and IL-1 signaling of NF-kB as well asregulators of AP-1, macrophage metalloproteinases, lymphotoxin andfurther insights into the role of MCP-1 in disease. Also discussed aredrug targets in rheumatoid and osteoarthritis, fibrotic diseases, 160 pp. Englisch. …

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Symbolic rewriting techniques are methods for deriving consequences from systems of equations, and are of great use when investigating the structure of the solutions. Such techniques appear in many important areas of research within computer algebra: - the Knuth-Bendix completion for groups, monoids and general term-rewriting systems, - the Buchberger algorithm for Gröbner bases, - the Ritt-Wu characteristic set method for ordinary differential equations, and - the Riquier-Janet method for partial differential equations. This volume contains invited and contributed papers to the Symbolic Rewriting Techniques workshop, which was held at the Centro Stefano Franscini in Ascona, Switzerland, from April 30 to May 4, 1995. That workshop brought together 40 researchers from various areas of rewriting techniques, the main goal being the investigation of common threads and methods. Following the workshops, each contribution was formally refereed and 14 papers were selected for publication. 300 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Although surprising, it seems fitting that a drug developed at the dawn of the era of rational drug design and therapeutics, methotrexate, should remain in common use for the therapy of so many different kinds of illnesses. Moreover, methotrexate has completely revolutionized the way in which medicine is practiced in a number of speciality areas. First developed to treat malignancies, methotrexate is now commonly used to treat gynecological problems, inflammatory arthritis, skin disease and probably other ailments as well. This work is designed to give a broad overview of the history of methotrexate's development, its prior use and its current therapeutic uses. As discussed in Chapter I, aminopterin and methotrexate were designed to inhibit mammalian folate metabolism but the concept of folic acid antag onism was soon applied to the development of antibacterial and anti parasitic agents. Trimethoprim and sulfa drugs were among the first antibiotics developed and they also remain quite useful today for the treat ment of a variety of infections. 152 pp. Englisch.…

Idioma: Inglés
Editorial: Birkhäuser Basel Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Fatty acids play an important role in the barrier function of skin and represent a major source of proinflammatory mediators such as prostaglandins, leukotrienes and other lipids in inflammatory skin disorders. This book combines the two major functions of fatty acids in skin biology. In the first part the biosynthesis of fatty acids in skin with its role in barrier function as well as the role of dietary fatty acids on skin cell function and in the treatment of inflammatory skin diseases is presented. The second part deals with skin as a source of proinflammatory eicosanoids, especially with the keratinocyte as a major cellular source. Metabolism of eicosanoids in skin, its role in psoriasis and atopic dermatitis as well as pharmacological inhibition of eicosanoid biosynthesis is reviewed. The book finishes with a chapter describing the methods used for quantification of fatty acids and derivatives in skin inflammation. Anyone interested in skin physiology would benefit from the overviews about the two sites of fatty acids' function in skin integrity and in skin inflammation. 196 pp. Englisch.…

Idioma: Inglés
Editorial: Springer, Basel, Birkhäuser Basel, Birkhäuser Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains a selection from the papers presented at the Fourth European Multigrid Conference, held in Amsterdam, July 6-9,1993. There were 78 registered participants from 14 different countries, and 56 presentations were given. The preceding conferences in this series were held in Cologne (1981, 1985) and in Bonn (1990). Also at the other side of the Atlantic special multigrid conferences are held regularly, at intervals of two years, always in Copper Mountain, Colorado, US. The Sixth Copper Mountain Conference on Multigrid Methods took place in April, 1993. Circumstances prevented us from putting a larger time interval between the Copper and Amsterdam meetings. The next European meeting is planned in 1996, a year later than the next Copper Meeting. When the first multigrid conference was held in 1981 there was no doubt about the usefulness of a conference dedicated specially to multigrid, because multigrid was a new and relatively unexplored subject, still in a pioneering stage, and pursued by specialists. The past twenty years have shown a rapid growth in theoretical understanding, useful applications and widespread acceptance of multi grid in the applied disciplines. Hence, one might ask whether there is still a need today for conferences specially dedicated to multigrid. The general consensus is that the answer is affirmative. New issues have arisen that are best addressed or need also be addressed from a special multigrid point of view. 358 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -The lung and its contiguous structures are commonly involved in several of the rheumatic diseases (Table 1), either by direct manifestation of disease or as a secondary effect from infection or complications of therapy. In this chapter, we detail the various pulmonary manifestations of the major rheu matological conditions. The common symptoms of pulmonary diseases and how frequently they are implicated in rheumatic disorders are review ed. In addition, radiology and physiology of the lung, diagnostic proce dures and therapeutic options are discussed. Table l. Respiratory associations of the rheumatic disorders Disease Airways Parenchyma Vessels WalVmuscles Lung Pleura Pulmonary Chest pleurisy hypertension Rheumatoid bronchiectasis, pneumonia, arthritis obliterative fibrosing effusion bronchiolitis alveolitis, empyema nodules Systemic pneumonia pleurisy hypertension lupus fibrosing effusion shrinking lungs erythematosus alveolitis, with high atelectasis diaphragm Systemic bronchiectasis fibrosing hypertension 'encased chest' sclerosis alveolitis, aspiration pneumonia Sjogren's bronchitis fibrosing alveolitis syndrome lymphoma Dermatomyositis aspiration myopathy polymyositis pneumonia, fibrosing alveolitis Ankylosing upper lobe cos- spondylitis fibrosis vertebral fixation joint Behget's haemorrhage aneurysm syndrome Relapsing upper airway polychondritis narrowing Pulmonary vasculitides nodules The Respiratory System in Rheumatic Diseases 25 1. 2. Respiratory Symptoms The most common respiratory symptoms in patients with rheumatic disease and pulmonary involvement are non-specific and include cough, breathlessness and chest pain and can be the result of involvement of air ways, lung parenchyma, pleura, chest wall or pulmonary vessels. 1. 3. Tissue Involvement 1. 3. 1. 292 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is concerned with the role played by modules of infinite length when dealing with problems in the representation theory of groups and algebras, but also in topology and geometry; it shows the intriguing interplay between finite and infinite length modules. 452 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Plate tectonics has significantly broadened our view of the dynamics of continental evolution, involving both the processes currently active at the surface and those extending deep into the interior of the Earth. Seismic anisotropy provides some of the most diagnostic evidence for mapping past and present deformation of the entire crustmantle system. This volume contains papers presented originally at an international workshop at the Chateau of Trest in the Czech Republic in 1996. This workshop brought together geophysicists and geologists who work in the field of observational and theoretical seismology, mineral and rock physics, gravity studies and geodynamic modelling. Topics include large-scale anisotropy of the Earth's mantle, mantle heterogeneity vs. anisotropy 3-D velocity and density structures and inferences on mantle dynamics, mineral and rock physics studies, and mathematical aspects of complex wave propagation. 520 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book presents the original proof of Gromov's compactness theorem for pseudo-holomorphic curves in detail. Local properties of pseudo-holomorphic curves are investigated and proved from a geometric viewpoint. Properties of particular interest are isoperimetric inequalities, a monotonicity formula, gradient bounds and the removal of singularities. 148 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Award-winning monograph of the Ferran Sunyer i Balaguer Prize 2002.The subject of this book is the study of automorphic distributions, by which is meant distributions on R 2 invariant under the linear action of SL(2,Z), and of the operators associated with such distributions under the Weyl rule of symbolic calculus. Researchers and postgraduates interested in pseudodifferential analyis, the theory of non-holomorphic modular forms, and symbolic calculi will benefit from the clear exposition and new results and insights. 260 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This book is devoted to a study of the unit groups of orders in skew fields, finite dimensional and central over the rational field; it thereby belongs to the field of noncommutative arithmetic. Its purpose is a synopsis of results and methods, including full proofs of the most important results. It is addressed to researchers in number theory and arithmetic groups. 92 pp. Englisch.…

Idioma: Inglés
Editorial: Birkhäuser Basel Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -As in so many fields of scientific endeavour following the molecular biology revo lution, our knowledge of the role of radicals not only in pathological states, but in basic physiology has developed exponentially. Indeed, our evolving concepts have, like so many political parties, been forced into dramatic 'V-turns' and contortions. Within our working lives, we have had to debate whether radicals made any con tribution to any pathology, whilst now it is difficult not to entertain the view that every physiological process is pivotally controlled by exquisitely sensitive radical reactions. Inflammation is, of course, an example of pathology evolving from physiology, and in this book we have called upon both scientists and clinicians who have research interests in the complex switching mechanisms that sustain these transi tions. The book as a whole explores, from a physiological standpoint, how deter ministic radical systems sensitive to their initial conditions can interdigitate, iterate and feed back to control diverse cellular processes that create the inflammatory response. Whilst systems such as these to a mathematician would provide the basis for a chaotic response, one is forced to marvel how, for all stages of an inflammatory reaction, this system appears exquisitely controlled, making therapeutic manipula tion both possible and, to some extent, predictable. 276 pp. Englisch.…

Idioma: Inglés
Editorial: Birkhäuser Basel, Springer Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Stroke is a leading cause of death in developed countries. However,current therapeutic strategies for stroke have been largelyunsuccessful. One possible explanation is that research andpharmacological management have focused on very early events in brainischemia. New research has shown that brain ischemia and trauma elicitstrong inflammatory reactions driven by both external and brain cells.The recognition of inflammation as a fundamental response to brainischemia provides novel opportunities for new anti-inflammatorytherapies.For the first time, an international body of researchers presents thelatest findings about the cellular and humoral aspects of immune andinflammatory reactions in the brain. The work may have an impact on thetreatment of neuroinjuries and ancillary brain diseases, and increasethe understanding of the roles infections and immune reactions play inthe brain milieu. 376 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -From the contents: C. Brater and M. D. Murray: The effects of NSAIDs on the kidney G. Edwards and A. H. Weston: Latest developments in potassium channel modulator drugs M.R. Juchau and Y. Huang: Chemical teratogenesis in humans: Biochemical and molecular mechanisms S.P. Gupta: Studies on cardiovascular drugs G. Polak: Antifungal chemotherapy: An everlasting battle O. Valdenaire: New insights into the bioamine receptor family 376 pp. Englisch. …

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -In step with our growing lifespan, dementia is becoming a widespreadhandicap to the health and well-being of individuals and a burden onhuman society world-wide. The increasing prevalence of this tragiccondition has stimulated an explosion of scientific research in the lastten years, which resulted in numerous profound insights and technicalinnovations. This timely volume presents both an overall and a detailedoverview of the current worldwide knowledge about the neuroscientificbasis of dementia.Leading authorities in their fields provide a far-reaching synthesis ofall topics in dementia research, including pathogenesis of dementia,neuroimaging of the earliest alterations, potential biological andgenetic markers for Alzheimer`s Disease and new therapeutic strategies.Each chapter discusses clinical implications and areas of controversy,highlights the wide range of current and future therapeuticpossibilities and indicates promising directions for further research. 324 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume contains the refereed proceedings of the Workshop on Cryptography and Computational Number Theory, CCNT'99, which has been held in Singapore during the week of November 22-26, 1999. The workshop was organized by the Centre for Systems Security of the Na tional University of Singapore. We gratefully acknowledge the financial support from the Singapore National Science and Technology Board under the grant num ber RP960668/M. The idea for this workshop grew out of the recognition of the recent, rapid development in various areas of cryptography and computational number the ory. The event followed the concept of the research programs at such well-known research institutions as the Newton Institute (UK), Oberwolfach and Dagstuhl (Germany), and Luminy (France). Accordingly, there were only invited lectures at the workshop with plenty of time for informal discussions. It was hoped and successfully achieved that the meeting would encourage and stimulate further research in information and computer security as well as in the design and implementation of number theoretic cryptosystems and other related areas. Another goal of the meeting was to stimulate collaboration and more active interaction between mathematicians, computer scientists, practical cryptographers and engineers in academia, industry and government. 392 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Discrete stochastics is the theory of discrete probability spaces. This undergraduate textbook gives a concise introduction into discrete stochastics in general, and into a variety of typical special topics in this field, such as information theory, fluctuation theory, and semigroups of stochastic matrices. The emphasis lies on probability theory rather than on statistical methodology. Motivations, interpretations, and numerous examples and exercises relate the mathematical theory to stochastic experience. 296 pp. Englisch.…

Idioma: Inglés
Editorial: Birkhäuser Basel Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume will be of great value to all those researchers in the area of the inflam matory response, notably academics, clinicians and members of the pharmaceutical industry. The book has in the main been restricted to three inducible enzymes, namely nitric oxide synthase (iNOS), cyclooxygenase (COX-2) and hemeoxygenase (HO-l), although matrix metalloproteinases, xanthine oxidoreductase and tissue transgluta minases are reviewed. The modulation of these enzymes is viewed as possible novel therapeutic advances in the area of inflammation and also cancer. The latter topic may well be the subject of a further book. It will be interesting to observe the progress of such new therapies in the next decade. Already some of these enzyme modulators have been approved for the treat ment of inflammatory disease, as evidenced by the new families of COX-2 inhibitors. We believe such advances will herald a series of new and exciting agents to be included in the clinician's armamentarium in the constant struggle against inflammatory disease. The editors wish to thank all contributors to this volume on inducible enzymes. It should however be stressed that the views expressed by the authors are personal and do not necessarily reflect those of the editors. Indeed, the reader may find con flicting statements in a number of the chapters. We believe that this is entirely appro priate as this volume reflects the latest work in a rapidly developing area. 228 pp. Englisch.…

Idioma: Inglés
Editorial: Birkhäuser Basel, Birkhäuser Basel Okt 2012, 2012
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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -This volume presents the proceedings of the 11th Conference on Problems and Methods in Mathematical Physics (11th TMP), held in Chemnitz, March 25-28, 1999. The conference was dedicated to the memory of Siegfried Prössdorf, who made important contributions to the theory and numerical analysis of operator equations and their applications in mathematical physics and mechanics. The main part of the book comprises original research papers. The topics are ranging from integral and pseudodifferential equations, boundary value problems, operator theory, boundary element and wavelet methods, approximation theory and inverse problems to various concrete problems and applications in physics and engineering, and reflect Prössdorf's broad spectrum of research activities. The volume also contains articles describing the life and mathematical achievements of Siegfried Prössdorf and includes a list of his publications. The book is addressed to a wide audience in the mathematical and engineering sciences. 536 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -These proceedings contain the main topics and results presented at the Fourth International Conference on Multivariate Approximation. The meeting took place during the week of September 24-29, 2000 at the now well-known 'Haus Bommerholz', the guest-house of the University of Dortmund. It hosted 43 participants from 16 countries, and the program included 9 invited one-hour lectures, 21 contributed talks, and two problem sessions. The articles collected here are carefully peer-refereed and suitably edited for publication. Following the tradition of this series of conferences, the meeting was aimed at advancing selected topics of Multivariate Approximation Theory. These include approximation on compact sets (such as spheres, balls, or compact ho mogeneous manifolds), spherical designs and energy functionals, interpolation by radial basis functions and by splines, frame theory and Gabor analysis, re finable function systems and subdivision, properties of harmonic, polyharmonic and blending functions, sampling and data compression, among others. The editors would like to express their thanks to all who have given their sup port to the conference, and to the preparation of this book. In particular, our thanks go to the Deutsche Forschungsgemeinschaft for their funding of the con ference, to the University of Dortmund, and to the staff of Haus Bommerholz for their help running the conference, and to the Universities of Dortmund and Duisburg for the financial support of this proceedings volume. 268 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -A set in complex Euclidean space is called C-convex if all its intersections with complex lines are contractible, and it is said to be linearly convex if its complement is a union of complex hyperplanes. These notions are intermediates between ordinary geometric convexity and pseudoconvexity. Their importance was first manifested in the pioneering work of André Martineau from about forty years ago. Since then a large number of new related results have been obtained by many different mathematicians. The present book puts the modern theory of complex linear convexity on a solid footing, and gives a thorough and up-to-date survey of its current status. Applications include the Fantappié transformation of analytic functionals, integral representation formulas, polynomial interpolation, and solutions to linear partial differential equations. 180 pp. Englisch.…

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Taschenbuch. Condición: Neu. This item is printed on demand - it takes 3-4 days longer - Neuware -Research into inflammatory mechanisms that may cause damage to the Alzheimer's disease (AD) brain has now been ongoing for nearly two decades. Some two dozen clinical studies have strongly suggested that conventional anti-inflammatory drugs may be useful to delay the onset or slow the progression of the disorder. Moreover, virtually all the major systems of the innate immune response appear to be present, and most are upregulated, in pathologically-vulnerable regions of the AD brain. These new findings are described in this volume - first in overview form, followed by chapters on topics of special interest. In many ways, to understand AD brain inflammation, one need only review a text on peripheral inflammation biology, leaving out the chapters on humoral medi ators and substituting microglia for macrophages. In several other key respects, however, AD brain inflammation is unique, due primarily to idiosyncratic interac tions of inflammatory mediators and mechanisms with classical AD pathology: amyloid ~ peptide(A~) deposits and neurofibrillary tangles (NFTs). For this reason, some key concepts about the inflammation that occurs in AD may warrant discus sion in preparation for the more detailed chapters that follow. 284 pp. Englisch.…